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The map label for this gene is hisI [H]

Identifier: 118476972

GI number: 118476972

Start: 1414474

End: 1414779

Strand: Direct

Name: hisI [H]

Synonym: BALH_1266

Alternate gene names: 118476972

Gene position: 1414474-1414779 (Clockwise)

Preceding gene: 118476971

Following gene: 118476973

Centisome position: 26.91

GC content: 34.64

Gene sequence:

>306_bases
ATGAAACCTAACTTTTCAAAAGGACTATTACCGGCAGTTGTAATTGAAGAAGGTACAAAAGAAGTTTTAATGCTAGCTTA
TATGAATGAAGAAGCATATGAAAAAACGCTAAAAACGAAAAGAACATGGTTTTATTCTCGTTCAAGAAGGTCGCTATGGA
ATAAAGGAGAAACGTCAGGTCATGTCCAACATGTGCAATCTCTTTATTTAGATTGTGATCAAGATTCAATTGTTGTTGTC
GTAAAGCAAGTTGGCCCAGCTTGCCATACGGGAGAAAAAACGTGTTTTCATTACAAAATTATATAG

Upstream 100 bases:

>100_bases
CAGTTGATGCAGCGTTAGCAGCATCCATCTTTCATTATGGCGAGGCGACAGTGCAGGACGTAAAGAGAAAGTTAAGAAAT
GCAAACGTCGAGGTGCGGTT

Downstream 100 bases:

>100_bases
GGGGATACATATGGAAAATACCTTCAAATTACTATTCGAAACAATTGGAGAACGAAAGAGAAATCCACTTCCTGAATCAT
ATACAAATTACTTGTTTTCA

Product: phosphoribosyl-AMP cyclohydrolase

Products: NA

Alternate protein names: PRA-CH [H]

Number of amino acids: Translated: 101; Mature: 101

Protein sequence:

>101_residues
MKPNFSKGLLPAVVIEEGTKEVLMLAYMNEEAYEKTLKTKRTWFYSRSRRSLWNKGETSGHVQHVQSLYLDCDQDSIVVV
VKQVGPACHTGEKTCFHYKII

Sequences:

>Translated_101_residues
MKPNFSKGLLPAVVIEEGTKEVLMLAYMNEEAYEKTLKTKRTWFYSRSRRSLWNKGETSGHVQHVQSLYLDCDQDSIVVV
VKQVGPACHTGEKTCFHYKII
>Mature_101_residues
MKPNFSKGLLPAVVIEEGTKEVLMLAYMNEEAYEKTLKTKRTWFYSRSRRSLWNKGETSGHVQHVQSLYLDCDQDSIVVV
VKQVGPACHTGEKTCFHYKII

Specific function: Histidine biosynthesis; second step. Histidine biosynthesis; third step. [C]

COG id: COG0139

COG function: function code E; Phosphoribosyl-AMP cyclohydrolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PRA-CH family [H]

Homologues:

Organism=Escherichia coli, GI2367128, Length=91, Percent_Identity=46.1538461538462, Blast_Score=100, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002496
- ProDom:   PD002610 [H]

Pfam domain/function: PF01502 PRA-CH [H]

EC number: =3.5.4.19 [H]

Molecular weight: Translated: 11624; Mature: 11624

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPNFSKGLLPAVVIEEGTKEVLMLAYMNEEAYEKTLKTKRTWFYSRSRRSLWNKGETSG
CCCCCCCCCCCEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
HVQHVQSLYLDCDQDSIVVVVKQVGPACHTGEKTCFHYKII
HHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEEEEC
>Mature Secondary Structure
MKPNFSKGLLPAVVIEEGTKEVLMLAYMNEEAYEKTLKTKRTWFYSRSRRSLWNKGETSG
CCCCCCCCCCCEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
HVQHVQSLYLDCDQDSIVVVVKQVGPACHTGEKTCFHYKII
HHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA