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The map label for this gene is dnaC [H]

Identifier: 118476572

GI number: 118476572

Start: 976128

End: 977423

Strand: Direct

Name: dnaC [H]

Synonym: BALH_0845

Alternate gene names: 118476572

Gene position: 976128-977423 (Clockwise)

Preceding gene: 118476571

Following gene: 118476574

Centisome position: 18.57

GC content: 43.83

Gene sequence:

>1296_bases
GTGGCGTCCATGAGTATTCAAAATGTGGAGGCGGAAAAGACGGTATTAGGTTCTCTATTACTTGATGGAGAGCTTATTAA
GGAGTGCCGTTTGACGGAGCAGTATTTTTCGATGCCAGTGCATAAGTCTATATTTCAGTTAATGCGAAAGATGGAAGGAG
AGGGGCAACCGATTGATCTTGTGACCTTCACTTCTAGGGTCGATCCGAATTTTTTGAAGGGGATCGGGGGAATGGAGTAT
TTTATAGGGTTAATGGATGGTGTGCCTACAACTGCGAACTTCTCATATTATGAGGGGCTTGTTCGAGGTGCCTGGAAAAT
GTATCAGGCGGGTGTTCTCGGGCACAAGATGGGAGAGCGCCTTATTGCGGAGAAGAGTGAGAAAATTATTGGTGAGACGA
TTACGGCACTTTGTGAGTTAGAGGAGAAGGACTGTGTATGTGAGTTTGATTTGAAGGATGCGCTAGTGGATTTATATGAA
GAGCTTCATCAAGATGCGAAAGAGATTACTGGTATTGGGACTGGTTATACATCGCTAAATAAAATGACGTGCGGATTGCA
GGAAGGTGATTTTGTCGTCCTTGGTGCGCGTCCTTCTATGGGGAAGACTGCGTTCGCACTAAATGTTGGACTGCATGCGG
CGAAGTCTGGATCGGCGGTTGGCCTATTTTCATTAGAGATGAGTAGTAAGCAATTGTTAAAACGGATGGCATCTTGCGTA
GGTGAAGTGTCAGGAGGTAGGCTGAAAAATCCGAAGCACCGTTTTGCAATGGAAGATTGGGAAAGGGTGAGTAAGGCGTT
TGCGGAGATTGGTGAATTGCCACTTGAGATTTACGACAATGCAGGGGTTACGGTGCAAGATATTTGGATGCAAACTCGTA
AGTTAAAGAGGAAGCATGGTGATAAAAAGATTTTAATTATTGTAGATTACTTGCAGCTTATTACGGGCGATCCGAAGCAT
AAGGGCAATCGATTTCAGGAAATTAGTGAGATTTCGCGTAAGCTTAAGTTATTAGCACGTGAATTAAATGTTTGTGTAGT
AGCATTATCGCAATTGTCTCGTTCTGTAGAGTCACGGCAAGATAAGCGTCCTCTTTTATCTGATTTAAGAGAGACCGGAC
AAATTGAGCAAGATGCGGATGTCATTATGCTTATGTATCGTGAAGATTATTACGATAAGGAAACGGTGCAGAAAGAGATG
ACGGAGATTCATGTGGCGAAGCATCGGAATGGGCCTGTTGGTAGTTTTAAGCTGAGGTTTTTGAAGGAGTTTGGGCGGTT
TGTGGAGATTGGATGA

Upstream 100 bases:

>100_bases
TTAGTACGGGGGAGACGGAGGAGTTTTTGGCGAGGTGTGGGGAGTGGGAGAAGAATGCGCCGTCTGAGGAAGAGTTGCAG
CGCTTTTTAGCGGAGCGCGG

Downstream 100 bases:

>100_bases
TAAAATAGAAGAAGGCATATAAAAAGGTAAAGGAGTGGTTACGGATGACAAAAGTAGGTCGTTTATATGAGCAAGAGAAG
CAAGAAGAAATTGATAAAGC

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MASMSIQNVEAEKTVLGSLLLDGELIKECRLTEQYFSMPVHKSIFQLMRKMEGEGQPIDLVTFTSRVDPNFLKGIGGMEY
FIGLMDGVPTTANFSYYEGLVRGAWKMYQAGVLGHKMGERLIAEKSEKIIGETITALCELEEKDCVCEFDLKDALVDLYE
ELHQDAKEITGIGTGYTSLNKMTCGLQEGDFVVLGARPSMGKTAFALNVGLHAAKSGSAVGLFSLEMSSKQLLKRMASCV
GEVSGGRLKNPKHRFAMEDWERVSKAFAEIGELPLEIYDNAGVTVQDIWMQTRKLKRKHGDKKILIIVDYLQLITGDPKH
KGNRFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQDKRPLLSDLRETGQIEQDADVIMLMYREDYYDKETVQKEM
TEIHVAKHRNGPVGSFKLRFLKEFGRFVEIG

Sequences:

>Translated_431_residues
MASMSIQNVEAEKTVLGSLLLDGELIKECRLTEQYFSMPVHKSIFQLMRKMEGEGQPIDLVTFTSRVDPNFLKGIGGMEY
FIGLMDGVPTTANFSYYEGLVRGAWKMYQAGVLGHKMGERLIAEKSEKIIGETITALCELEEKDCVCEFDLKDALVDLYE
ELHQDAKEITGIGTGYTSLNKMTCGLQEGDFVVLGARPSMGKTAFALNVGLHAAKSGSAVGLFSLEMSSKQLLKRMASCV
GEVSGGRLKNPKHRFAMEDWERVSKAFAEIGELPLEIYDNAGVTVQDIWMQTRKLKRKHGDKKILIIVDYLQLITGDPKH
KGNRFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQDKRPLLSDLRETGQIEQDADVIMLMYREDYYDKETVQKEM
TEIHVAKHRNGPVGSFKLRFLKEFGRFVEIG
>Mature_430_residues
ASMSIQNVEAEKTVLGSLLLDGELIKECRLTEQYFSMPVHKSIFQLMRKMEGEGQPIDLVTFTSRVDPNFLKGIGGMEYF
IGLMDGVPTTANFSYYEGLVRGAWKMYQAGVLGHKMGERLIAEKSEKIIGETITALCELEEKDCVCEFDLKDALVDLYEE
LHQDAKEITGIGTGYTSLNKMTCGLQEGDFVVLGARPSMGKTAFALNVGLHAAKSGSAVGLFSLEMSSKQLLKRMASCVG
EVSGGRLKNPKHRFAMEDWERVSKAFAEIGELPLEIYDNAGVTVQDIWMQTRKLKRKHGDKKILIIVDYLQLITGDPKHK
GNRFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQDKRPLLSDLRETGQIEQDADVIMLMYREDYYDKETVQKEMT
EIHVAKHRNGPVGSFKLRFLKEFGRFVEIG

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=442, Percent_Identity=38.2352941176471, Blast_Score=269, Evalue=3e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 48502; Mature: 48371

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASMSIQNVEAEKTVLGSLLLDGELIKECRLTEQYFSMPVHKSIFQLMRKMEGEGQPIDL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEE
VTFTSRVDPNFLKGIGGMEYFIGLMDGVPTTANFSYYEGLVRGAWKMYQAGVLGHKMGER
EEECCCCCHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIAEKSEKIIGETITALCELEEKDCVCEFDLKDALVDLYEELHQDAKEITGIGTGYTSLN
HHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
KMTCGLQEGDFVVLGARPSMGKTAFALNVGLHAAKSGSAVGLFSLEMSSKQLLKRMASCV
HHCCCCCCCCEEEEECCCCCCCEEEEEECCCEECCCCCEEEEEEECCCHHHHHHHHHHHH
GEVSGGRLKNPKHRFAMEDWERVSKAFAEIGELPLEIYDNAGVTVQDIWMQTRKLKRKHG
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHCC
DKKILIIVDYLQLITGDPKHKGNRFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQ
CCEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DKRPLLSDLRETGQIEQDADVIMLMYREDYYDKETVQKEMTEIHVAKHRNGPVGSFKLRF
CCCHHHHHHHHCCCCCCCCCEEEEEEHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHH
LKEFGRFVEIG
HHHHHHHCCCC
>Mature Secondary Structure 
ASMSIQNVEAEKTVLGSLLLDGELIKECRLTEQYFSMPVHKSIFQLMRKMEGEGQPIDL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEE
VTFTSRVDPNFLKGIGGMEYFIGLMDGVPTTANFSYYEGLVRGAWKMYQAGVLGHKMGER
EEECCCCCHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIAEKSEKIIGETITALCELEEKDCVCEFDLKDALVDLYEELHQDAKEITGIGTGYTSLN
HHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
KMTCGLQEGDFVVLGARPSMGKTAFALNVGLHAAKSGSAVGLFSLEMSSKQLLKRMASCV
HHCCCCCCCCEEEEECCCCCCCEEEEEECCCEECCCCCEEEEEEECCCHHHHHHHHHHHH
GEVSGGRLKNPKHRFAMEDWERVSKAFAEIGELPLEIYDNAGVTVQDIWMQTRKLKRKHG
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHCC
DKKILIIVDYLQLITGDPKHKGNRFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQ
CCEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DKRPLLSDLRETGQIEQDADVIMLMYREDYYDKETVQKEMTEIHVAKHRNGPVGSFKLRF
CCCHHHHHHHHCCCCCCCCCEEEEEEHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHH
LKEFGRFVEIG
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]