Click here to switch to the map view.

The map label for this gene is yrkH [H]

Identifier: 118476442

GI number: 118476442

Start: 815326

End: 816456

Strand: Direct

Name: yrkH [H]

Synonym: BALH_0706

Alternate gene names: 118476442

Gene position: 815326-816456 (Clockwise)

Preceding gene: 118476441

Following gene: 118476443

Centisome position: 15.51

GC content: 35.9

Gene sequence:

>1131_bases
ATGGAAGTTAAATTATTACAAGCAAAAGATGTTGCAGAGAAAGTTTTATTCGGAGAGTTGTTTATTTTAGATGTTCGTAA
TGAGATGGATTATGAAGATTGGAAAATTGAAGGGAAACAAATCTCATCTATAAATAAACCGTATTTTGATTTGTTAGATG
GTGTAGATCATATTGTAAGTGAATTACCTAAAGATAAAGATGTTTTAGTAGTATGTGCAAAAGAAGGGTCTTCTATATTT
GTGGCAGAGCAATTAACAGAGGCTGGATTAGAAAATATTTATTATTTAGCTGGTGGTATGAAGGCTTGGAGTGAATATGT
AAAGCCTATAAAAGTTGGAGATTTAAAAAATGGCGGAAGTATGTACCAGTTTAACCGCCTTGGAAAAGGCTGTTTATCTT
ATATGGTCGTTTCAAACGGTGAAGCAGCAGTTATTGATGCAATAAGAACAGTTGAAGCGTATGAACAATTTGCGAAAGAG
AATGACGTTACGATTACGAATGTAATGGATACACATTTACATGCAGACCATATTTCTGGAGGACGTAAGTTAGCGGAAAA
AGTAGGGGGTACGTATTGGTTACCGCCAAAAGATGCGGAGGAAGTTGTTTTCTCATATGAACCGCTCGTTGAAGGATCTG
TTATTACGATGGGGGGTACTAAAATTGAAATTGATGCATTATACTCACCGGGGCATACGATTGGAAGTACATCATTTATT
GTAGATGATTCCTATTTATTATCAGGCGATATTTTATTTGTAGATTCCATCGGGCGTCCAGATCTTGCTGGGAAGGCTGA
AGATTGGGTAAGTGATTTACGTAATACTTTGTATAGCCGATATAAAGAACTATCTCAAAATTTAATTGTGTTACCGGCTC
ATTATTCAAAAATAAGTGAAATGGACGAAAGTGGTATTGTTAGTGCAAAATTAAAAGATTTATTTGAGCATAATGCCGGA
TTAAATATTGAGGATGAGGGAGAGTTCCGTAAAGTGGTAACAGAGAATTTACCACCTCAACCAAATGCATATGAAGAAAT
CCGTCAAACCAATATGGGTAAAATTCACCCGAGTGTGGATGAAGAGCGTGAAATGGAGATTGGTCCAAATCGTTGTGCAG
TTCACAAATAA

Upstream 100 bases:

>100_bases
ATACAAATGTGAAAAATGTTATTCCCGGTATGATAGAGTGGCAAGGGAATATAGAGAATTAAATTTTTTTAAATAAAAAT
ATACCTCAGGGGGTAAGAAG

Downstream 100 bases:

>100_bases
ATAAATAAATAAATAAATAAATGAAAAATGGAGGAATAGATGATGAATGTAAAACAAGTATTAGATGCGAAAGATTTAGC
ATGTCCAATGCCGATTGTAA

Product: metallo-beta-lactamase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MEVKLLQAKDVAEKVLFGELFILDVRNEMDYEDWKIEGKQISSINKPYFDLLDGVDHIVSELPKDKDVLVVCAKEGSSIF
VAEQLTEAGLENIYYLAGGMKAWSEYVKPIKVGDLKNGGSMYQFNRLGKGCLSYMVVSNGEAAVIDAIRTVEAYEQFAKE
NDVTITNVMDTHLHADHISGGRKLAEKVGGTYWLPPKDAEEVVFSYEPLVEGSVITMGGTKIEIDALYSPGHTIGSTSFI
VDDSYLLSGDILFVDSIGRPDLAGKAEDWVSDLRNTLYSRYKELSQNLIVLPAHYSKISEMDESGIVSAKLKDLFEHNAG
LNIEDEGEFRKVVTENLPPQPNAYEEIRQTNMGKIHPSVDEEREMEIGPNRCAVHK

Sequences:

>Translated_376_residues
MEVKLLQAKDVAEKVLFGELFILDVRNEMDYEDWKIEGKQISSINKPYFDLLDGVDHIVSELPKDKDVLVVCAKEGSSIF
VAEQLTEAGLENIYYLAGGMKAWSEYVKPIKVGDLKNGGSMYQFNRLGKGCLSYMVVSNGEAAVIDAIRTVEAYEQFAKE
NDVTITNVMDTHLHADHISGGRKLAEKVGGTYWLPPKDAEEVVFSYEPLVEGSVITMGGTKIEIDALYSPGHTIGSTSFI
VDDSYLLSGDILFVDSIGRPDLAGKAEDWVSDLRNTLYSRYKELSQNLIVLPAHYSKISEMDESGIVSAKLKDLFEHNAG
LNIEDEGEFRKVVTENLPPQPNAYEEIRQTNMGKIHPSVDEEREMEIGPNRCAVHK
>Mature_376_residues
MEVKLLQAKDVAEKVLFGELFILDVRNEMDYEDWKIEGKQISSINKPYFDLLDGVDHIVSELPKDKDVLVVCAKEGSSIF
VAEQLTEAGLENIYYLAGGMKAWSEYVKPIKVGDLKNGGSMYQFNRLGKGCLSYMVVSNGEAAVIDAIRTVEAYEQFAKE
NDVTITNVMDTHLHADHISGGRKLAEKVGGTYWLPPKDAEEVVFSYEPLVEGSVITMGGTKIEIDALYSPGHTIGSTSFI
VDDSYLLSGDILFVDSIGRPDLAGKAEDWVSDLRNTLYSRYKELSQNLIVLPAHYSKISEMDESGIVSAKLKDLFEHNAG
LNIEDEGEFRKVVTENLPPQPNAYEEIRQTNMGKIHPSVDEEREMEIGPNRCAVHK

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Escherichia coli, GI1787158, Length=173, Percent_Identity=28.3236994219653, Blast_Score=66, Evalue=5e-12,
Organism=Drosophila melanogaster, GI221330176, Length=211, Percent_Identity=28.436018957346, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR001763 [H]

Pfam domain/function: PF00753 Lactamase_B; PF00581 Rhodanese [H]

EC number: NA

Molecular weight: Translated: 41896; Mature: 41896

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVKLLQAKDVAEKVLFGELFILDVRNEMDYEDWKIEGKQISSINKPYFDLLDGVDHIVS
CCEEEECHHHHHHHHHHCEEEEEEECCCCCCCCEEECCHHHCCCCCCHHHHHHHHHHHHH
ELPKDKDVLVVCAKEGSSIFVAEQLTEAGLENIYYLAGGMKAWSEYVKPIKVGDLKNGGS
HCCCCCCEEEEEECCCCEEEEHHHHHHHHHHHEEEECCCHHHHHHHCCCEEECCCCCCCC
MYQFNRLGKGCLSYMVVSNGEAAVIDAIRTVEAYEQFAKENDVTITNVMDTHLHADHISG
CHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCC
GRKLAEKVGGTYWLPPKDAEEVVFSYEPLVEGSVITMGGTKIEIDALYSPGHTIGSTSFI
HHHHHHHCCCEEECCCCCHHHHHEECCCCCCCCEEEECCCEEEEEEEECCCCCCCCEEEE
VDDSYLLSGDILFVDSIGRPDLAGKAEDWVSDLRNTLYSRYKELSQNLIVLPAHYSKISE
EECCEEEECCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHH
MDESGIVSAKLKDLFEHNAGLNIEDEGEFRKVVTENLPPQPNAYEEIRQTNMGKIHPSVD
CCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCC
EEREMEIGPNRCAVHK
CCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEVKLLQAKDVAEKVLFGELFILDVRNEMDYEDWKIEGKQISSINKPYFDLLDGVDHIVS
CCEEEECHHHHHHHHHHCEEEEEEECCCCCCCCEEECCHHHCCCCCCHHHHHHHHHHHHH
ELPKDKDVLVVCAKEGSSIFVAEQLTEAGLENIYYLAGGMKAWSEYVKPIKVGDLKNGGS
HCCCCCCEEEEEECCCCEEEEHHHHHHHHHHHEEEECCCHHHHHHHCCCEEECCCCCCCC
MYQFNRLGKGCLSYMVVSNGEAAVIDAIRTVEAYEQFAKENDVTITNVMDTHLHADHISG
CHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCC
GRKLAEKVGGTYWLPPKDAEEVVFSYEPLVEGSVITMGGTKIEIDALYSPGHTIGSTSFI
HHHHHHHCCCEEECCCCCHHHHHEECCCCCCCCEEEECCCEEEEEEEECCCCCCCCEEEE
VDDSYLLSGDILFVDSIGRPDLAGKAEDWVSDLRNTLYSRYKELSQNLIVLPAHYSKISE
EECCEEEECCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHH
MDESGIVSAKLKDLFEHNAGLNIEDEGEFRKVVTENLPPQPNAYEEIRQTNMGKIHPSVD
CCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCC
EEREMEIGPNRCAVHK
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]