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The map label for this gene is rocR [H]

Identifier: 118476180

GI number: 118476180

Start: 487608

End: 489011

Strand: Reverse

Name: rocR [H]

Synonym: BALH_0427

Alternate gene names: 118476180

Gene position: 489011-487608 (Counterclockwise)

Preceding gene: 118476184

Following gene: 118476173

Centisome position: 9.3

GC content: 34.19

Gene sequence:

>1404_bases
ATGCGTACAGAAGACATTAATTTTAAACAGATCATTGAAATGAATATGCTATATGAAACTTTACTCAATAAACTCGATAT
CGGGATTCATATTATTAATGAGGAAAGTAAAACGATTATCTATAACCGCAAAATGATGGAAATTGAATCAATGGAACGCT
CAGATGTGTTATATAAAAGTCCTTTAGAAGTATTCGCATTTGAAGAAAATAAAAATAGTACTCTTATAGAAGCATTAAAA
TTAGGAAAAACAAACAAAAATATAAAACAGACGTACTTTAACAATAAAGGGCAAGAAATCACGACGATTAACGATACTTT
CCCTATAATAGAAAATGGAAAAATTAAAGGCGCTATTGAAATTTCAAAAGAGATGAATCACTTAAAGCAAACAATAAAAA
TGGACTCTTTCCGAAAACAAAACACTAAATTTACCTTTGATCACATAATTGGTGATTCTGAAGCCATTCAATCAACCATT
GCGGAAGGAAAAAGGGTAATTCGTACATCTTCCTCCATACTTCTCGTAGGAGAAACAGGAACTGGAAAAGAACTATTTGC
ACAAAGTATCCATAATGAAAGTCAACGTTCAACAAAACCGTTCATTTCACAAAACTGTGCCGCTATACCTGATACGTTAA
TGGAAAGTTTATTATTTGGTACGAACCGAGGTGCATTTACAGGAGCGATTGATAAAGCTGGTTTATTTGAAGAAGCGAAC
GGAGGCACTTTATTATTAGATGAGATCAACTCATTAAGTCCAGCACTTCAAGCAAAGTTGCTGCGAGCTATACAAGAAAA
AACAATACGAAGAATCGGGGGCACACAAGAAAAAGAAATTGATGTTCGTATTATAGCAACTATTAATGAAGACCCCCTTG
AAGCTATTACACACAATCGATTACGGGAAGACTTATATTACCGATTAAGCGTCGTTACTTTATGCCTCCCGCCTTTACGT
GAACGAAAAGAAGATATTTCCGCTCTTGTTCAGCACTTTATCGAAAAGTACAACATTCAATTTGGACTCGCTGTAACGGA
TGTAGATATACATGTAAGAGAATTCTTGTATGCATATGATTGGCCTGGAAACGTCCGAGAATTGGAACATATCATTGAAG
GTTCAATGAACTTGGTTGAAGATGAAAATATTATTACGGCGTTTCATCTTCCTACTCGCTTTCGCGAACAAATAAAAAAA
GAATTCAATACGCAACCTTTCCTAACTAATAACGCCACTGATGCGCCAAAAACATTAAAGCACACAATAGAAGAAATGGA
AAAAAACTACATCACTCAAATTTTGAAAGAGTATCACGGTAATATTTCACAAGCTGCAAAGTTTTTGGGGTTAAGTAGGC
AAAACTTACAATATCGAATTAAAAAACTGCATTTACACATATGA

Upstream 100 bases:

>100_bases
TTAAAAAGAAAATAGCAAAAAAATTTTGCGGTTTTATAAGAATTTTAATAAAATTATAAAAAGTCAGTCTTCATAGGGTG
GAATGAGGAGAAGATAATCT

Downstream 100 bases:

>100_bases
AATGAACATTTCTCCAAGTGCAAAAATAACTTGGTAAAATATGTTACAATAAACATATAACATACTAGAAAGGAACGATA
TATATGAGTAATGATAACAA

Product: arginine utilization regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MRTEDINFKQIIEMNMLYETLLNKLDIGIHIINEESKTIIYNRKMMEIESMERSDVLYKSPLEVFAFEENKNSTLIEALK
LGKTNKNIKQTYFNNKGQEITTINDTFPIIENGKIKGAIEISKEMNHLKQTIKMDSFRKQNTKFTFDHIIGDSEAIQSTI
AEGKRVIRTSSSILLVGETGTGKELFAQSIHNESQRSTKPFISQNCAAIPDTLMESLLFGTNRGAFTGAIDKAGLFEEAN
GGTLLLDEINSLSPALQAKLLRAIQEKTIRRIGGTQEKEIDVRIIATINEDPLEAITHNRLREDLYYRLSVVTLCLPPLR
ERKEDISALVQHFIEKYNIQFGLAVTDVDIHVREFLYAYDWPGNVRELEHIIEGSMNLVEDENIITAFHLPTRFREQIKK
EFNTQPFLTNNATDAPKTLKHTIEEMEKNYITQILKEYHGNISQAAKFLGLSRQNLQYRIKKLHLHI

Sequences:

>Translated_467_residues
MRTEDINFKQIIEMNMLYETLLNKLDIGIHIINEESKTIIYNRKMMEIESMERSDVLYKSPLEVFAFEENKNSTLIEALK
LGKTNKNIKQTYFNNKGQEITTINDTFPIIENGKIKGAIEISKEMNHLKQTIKMDSFRKQNTKFTFDHIIGDSEAIQSTI
AEGKRVIRTSSSILLVGETGTGKELFAQSIHNESQRSTKPFISQNCAAIPDTLMESLLFGTNRGAFTGAIDKAGLFEEAN
GGTLLLDEINSLSPALQAKLLRAIQEKTIRRIGGTQEKEIDVRIIATINEDPLEAITHNRLREDLYYRLSVVTLCLPPLR
ERKEDISALVQHFIEKYNIQFGLAVTDVDIHVREFLYAYDWPGNVRELEHIIEGSMNLVEDENIITAFHLPTRFREQIKK
EFNTQPFLTNNATDAPKTLKHTIEEMEKNYITQILKEYHGNISQAAKFLGLSRQNLQYRIKKLHLHI
>Mature_467_residues
MRTEDINFKQIIEMNMLYETLLNKLDIGIHIINEESKTIIYNRKMMEIESMERSDVLYKSPLEVFAFEENKNSTLIEALK
LGKTNKNIKQTYFNNKGQEITTINDTFPIIENGKIKGAIEISKEMNHLKQTIKMDSFRKQNTKFTFDHIIGDSEAIQSTI
AEGKRVIRTSSSILLVGETGTGKELFAQSIHNESQRSTKPFISQNCAAIPDTLMESLLFGTNRGAFTGAIDKAGLFEEAN
GGTLLLDEINSLSPALQAKLLRAIQEKTIRRIGGTQEKEIDVRIIATINEDPLEAITHNRLREDLYYRLSVVTLCLPPLR
ERKEDISALVQHFIEKYNIQFGLAVTDVDIHVREFLYAYDWPGNVRELEHIIEGSMNLVEDENIITAFHLPTRFREQIKK
EFNTQPFLTNNATDAPKTLKHTIEEMEKNYITQILKEYHGNISQAAKFLGLSRQNLQYRIKKLHLHI

Specific function: Positive regulator of arginine catabolism. Controls the transcription of the two operons rocABC and rocDEF and probably acts by binding to the corresponding upstream activating sequences [H]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=345, Percent_Identity=40.8695652173913, Blast_Score=265, Evalue=6e-72,
Organism=Escherichia coli, GI1790437, Length=391, Percent_Identity=36.3171355498721, Blast_Score=228, Evalue=5e-61,
Organism=Escherichia coli, GI87082117, Length=323, Percent_Identity=39.6284829721362, Blast_Score=228, Evalue=9e-61,
Organism=Escherichia coli, GI1789233, Length=479, Percent_Identity=31.5240083507307, Blast_Score=224, Evalue=9e-60,
Organism=Escherichia coli, GI87082152, Length=331, Percent_Identity=39.2749244712991, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI1788905, Length=383, Percent_Identity=34.4647519582245, Blast_Score=211, Evalue=5e-56,
Organism=Escherichia coli, GI1789087, Length=327, Percent_Identity=39.7553516819572, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1790299, Length=330, Percent_Identity=36.0606060606061, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1786524, Length=334, Percent_Identity=35.3293413173653, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1787583, Length=343, Percent_Identity=32.6530612244898, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI87081872, Length=324, Percent_Identity=33.3333333333333, Blast_Score=171, Evalue=9e-44,
Organism=Escherichia coli, GI87081858, Length=445, Percent_Identity=28.0898876404494, Blast_Score=146, Evalue=4e-36,
Organism=Escherichia coli, GI1789828, Length=239, Percent_Identity=34.7280334728033, Blast_Score=121, Evalue=8e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR000014
- InterPro:   IPR013656
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF08448 PAS_4; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 53607; Mature: 53607

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTEDINFKQIIEMNMLYETLLNKLDIGIHIINEESKTIIYNRKMMEIESMERSDVLYKS
CCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECHHHHHHHCCCCCCHHCC
PLEVFAFEENKNSTLIEALKLGKTNKNIKQTYFNNKGQEITTINDTFPIIENGKIKGAIE
CCEEEEEECCCCHHHHHHHHHCCCCCCHHHHHCCCCCCEEEEECCCCCCEECCCEEEEEE
ISKEMNHLKQTIKMDSFRKQNTKFTFDHIIGDSEAIQSTIAEGKRVIRTSSSILLVGETG
HHHHHHHHHHHHHHHHHHHCCCCEEHHHHCCCHHHHHHHHHHCHHEEEECCCEEEEECCC
TGKELFAQSIHNESQRSTKPFISQNCAAIPDTLMESLLFGTNRGAFTGAIDKAGLFEEAN
CCHHHHHHHHHCCHHHCCCCHHHCCCCCCHHHHHHHHHHCCCCCCEECCCCCCCCCCCCC
GGTLLLDEINSLSPALQAKLLRAIQEKTIRRIGGTQEKEIDVRIIATINEDPLEAITHNR
CCEEEEECHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHH
LREDLYYRLSVVTLCLPPLRERKEDISALVQHFIEKYNIQFGLAVTDVDIHVREFLYAYD
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEECHHHHHHHHHHCC
WPGNVRELEHIIEGSMNLVEDENIITAFHLPTRFREQIKKEFNTQPFLTNNATDAPKTLK
CCCCHHHHHHHHHCCCCEECCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
HTIEEMEKNYITQILKEYHGNISQAAKFLGLSRQNLQYRIKKLHLHI
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRTEDINFKQIIEMNMLYETLLNKLDIGIHIINEESKTIIYNRKMMEIESMERSDVLYKS
CCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECHHHHHHHCCCCCCHHCC
PLEVFAFEENKNSTLIEALKLGKTNKNIKQTYFNNKGQEITTINDTFPIIENGKIKGAIE
CCEEEEEECCCCHHHHHHHHHCCCCCCHHHHHCCCCCCEEEEECCCCCCEECCCEEEEEE
ISKEMNHLKQTIKMDSFRKQNTKFTFDHIIGDSEAIQSTIAEGKRVIRTSSSILLVGETG
HHHHHHHHHHHHHHHHHHHCCCCEEHHHHCCCHHHHHHHHHHCHHEEEECCCEEEEECCC
TGKELFAQSIHNESQRSTKPFISQNCAAIPDTLMESLLFGTNRGAFTGAIDKAGLFEEAN
CCHHHHHHHHHCCHHHCCCCHHHCCCCCCHHHHHHHHHHCCCCCCEECCCCCCCCCCCCC
GGTLLLDEINSLSPALQAKLLRAIQEKTIRRIGGTQEKEIDVRIIATINEDPLEAITHNR
CCEEEEECHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHH
LREDLYYRLSVVTLCLPPLRERKEDISALVQHFIEKYNIQFGLAVTDVDIHVREFLYAYD
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEECHHHHHHHHHHCC
WPGNVRELEHIIEGSMNLVEDENIITAFHLPTRFREQIKKEFNTQPFLTNNATDAPKTLK
CCCCHHHHHHHHHCCCCEECCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
HTIEEMEKNYITQILKEYHGNISQAAKFLGLSRQNLQYRIKKLHLHI
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8113162; 9384377 [H]