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The map label for this gene is benK [H]

Identifier: 118476110

GI number: 118476110

Start: 405463

End: 406773

Strand: Reverse

Name: benK [H]

Synonym: BALH_0354

Alternate gene names: 118476110

Gene position: 406773-405463 (Counterclockwise)

Preceding gene: 118476111

Following gene: 118476107

Centisome position: 7.74

GC content: 37.83

Gene sequence:

>1311_bases
GTGAATACTATGCAACCTTCAGCTCCACCTCATCTAGAATCTACAAAAACCATCTTTTCAAACTCTATTACAAAACTTGT
TGTTTTTATTTGTTGGCTAGCCATTCTAGCTGACGGCTATGATTTAGGTATTTACGGGGCCGTTCTGCCTAAGCTACTGG
AAGACAACAGCTGGGCACTATCACCAGCTCATGCTGGTACAATTGCAAGCTATGCTTTGTTTGGAATGTTTATTGGCGCT
ATTCTAGTTGGAACTATTACAGATCTAATTGGACGAAAATGGACACTTATATGCTGTTTAGCACTTTTTTCTATTACAAT
GGGCCTAGCTGCTATCGCTCTTTCTCCTGAATTATTTGGGCTATGGCGATTTATCGGAGGAATTGGACTAGGCGGTGTCA
TTCCAACAGCTTCCGCACTTACTGTTGAATATTCACCAAAAAAGCGACAATCTTTTATTTATGCTCTTATGTTTACTGGC
TATCCTTTAGGTATCGTGTTAGGCGCTATTTTGTCCATGTTTATGTTAGAAGACTTCGGATGGAGAATTATGTTTGGCAT
CGGAATGATTCCACTACTCCTCATTCCTTTCATTATTCGTTATTTACCTGAATCCATTCAATTTTTATTATCACGTAATC
GCCAAGAAGAAGTGGATAAAATTCTTAATCGTTTTCAAATTGAATTCCATGCAAAAGAGAAAACTCATCAAGCCCCATCT
AATATACGAAAGAAAAATGGATTTCTTACTTTATTCTCAAAAGAATACATAAAAGCAACGCTGCTTTTTTGGATCACTTA
TATAATGGGGATGTTTTTAATATACGGTTTAAATACTTGGTTACCTCAGATGATGCGACAGGCAGGATATCCTCTTGGAT
CTAGTTTATCATTTCTACTTATGCTAAATATTACCGCCGCTATCGGCGCATTATTTGCTGGAGCAATCGCGGATCGTATA
GGAGCCAAAATCGTTATTAGCATCTCCTATCTTATGGCAGCTATATGTATTGGACTATTAACAATTAAACCATCTGTTAC
AATCATCTATCTTTTAATTGGCCTTGCTGGGATTGGATCAGTTGGCATTACTCAAATATTAAATGCATATGTGACACAAT
ACTTCCCATCCCATATCCGAGCTACTTCCTTAGGTTGGGGACTTGGACTTGGCCGAGTTGGTGCGATTGCTGCTCCTATT
CTTATCGGTATTATTATGACAATGCAATATGATTTAGCATGGAATTTCTATTTATTCTCATTCGCAGGTCTTCTCGCAGC
TATATCTGTTTTCCTTATTCCTGCAAAGTAA

Upstream 100 bases:

>100_bases
CTTCTTTATTTGTTATAAAACCTTTTCAGATAAATTTCGACAGGAAGGAGGGAAATATTAACATGAAATAAAATAATATA
TTCATCTACAAATAAAAGAG

Downstream 100 bases:

>100_bases
AAAAGGGCACAAATTTACTCGTGCTCTTTTTTGTATACTTCGAATAACATATCTCGAAACAATGTATTTAAACTCTCAAT
ATCTATCCCTGATCCCTTTT

Product: MFS family benzoate membrane transporter

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MNTMQPSAPPHLESTKTIFSNSITKLVVFICWLAILADGYDLGIYGAVLPKLLEDNSWALSPAHAGTIASYALFGMFIGA
ILVGTITDLIGRKWTLICCLALFSITMGLAAIALSPELFGLWRFIGGIGLGGVIPTASALTVEYSPKKRQSFIYALMFTG
YPLGIVLGAILSMFMLEDFGWRIMFGIGMIPLLLIPFIIRYLPESIQFLLSRNRQEEVDKILNRFQIEFHAKEKTHQAPS
NIRKKNGFLTLFSKEYIKATLLFWITYIMGMFLIYGLNTWLPQMMRQAGYPLGSSLSFLLMLNITAAIGALFAGAIADRI
GAKIVISISYLMAAICIGLLTIKPSVTIIYLLIGLAGIGSVGITQILNAYVTQYFPSHIRATSLGWGLGLGRVGAIAAPI
LIGIIMTMQYDLAWNFYLFSFAGLLAAISVFLIPAK

Sequences:

>Translated_436_residues
MNTMQPSAPPHLESTKTIFSNSITKLVVFICWLAILADGYDLGIYGAVLPKLLEDNSWALSPAHAGTIASYALFGMFIGA
ILVGTITDLIGRKWTLICCLALFSITMGLAAIALSPELFGLWRFIGGIGLGGVIPTASALTVEYSPKKRQSFIYALMFTG
YPLGIVLGAILSMFMLEDFGWRIMFGIGMIPLLLIPFIIRYLPESIQFLLSRNRQEEVDKILNRFQIEFHAKEKTHQAPS
NIRKKNGFLTLFSKEYIKATLLFWITYIMGMFLIYGLNTWLPQMMRQAGYPLGSSLSFLLMLNITAAIGALFAGAIADRI
GAKIVISISYLMAAICIGLLTIKPSVTIIYLLIGLAGIGSVGITQILNAYVTQYFPSHIRATSLGWGLGLGRVGAIAAPI
LIGIIMTMQYDLAWNFYLFSFAGLLAAISVFLIPAK
>Mature_436_residues
MNTMQPSAPPHLESTKTIFSNSITKLVVFICWLAILADGYDLGIYGAVLPKLLEDNSWALSPAHAGTIASYALFGMFIGA
ILVGTITDLIGRKWTLICCLALFSITMGLAAIALSPELFGLWRFIGGIGLGGVIPTASALTVEYSPKKRQSFIYALMFTG
YPLGIVLGAILSMFMLEDFGWRIMFGIGMIPLLLIPFIIRYLPESIQFLLSRNRQEEVDKILNRFQIEFHAKEKTHQAPS
NIRKKNGFLTLFSKEYIKATLLFWITYIMGMFLIYGLNTWLPQMMRQAGYPLGSSLSFLLMLNITAAIGALFAGAIADRI
GAKIVISISYLMAAICIGLLTIKPSVTIIYLLIGLAGIGSVGITQILNAYVTQYFPSHIRATSLGWGLGLGRVGAIAAPI
LIGIIMTMQYDLAWNFYLFSFAGLLAAISVFLIPAK

Specific function: Probable uptake of benzoate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=425, Percent_Identity=26.5882352941176, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI216548223, Length=309, Percent_Identity=23.6245954692557, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI7662270, Length=309, Percent_Identity=22.3300970873786, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI166064021, Length=369, Percent_Identity=24.6612466124661, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI87081723, Length=387, Percent_Identity=28.6821705426357, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI87082404, Length=425, Percent_Identity=25.1764705882353, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI87082159, Length=371, Percent_Identity=28.3018867924528, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1786229, Length=391, Percent_Identity=27.3657289002558, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1788074, Length=367, Percent_Identity=24.5231607629428, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082231, Length=425, Percent_Identity=20.7058823529412, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788068, Length=377, Percent_Identity=26.2599469496021, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1789312, Length=349, Percent_Identity=26.3610315186246, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789207, Length=352, Percent_Identity=23.0113636363636, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790550, Length=427, Percent_Identity=24.5901639344262, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=429, Percent_Identity=25.1748251748252, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71989525, Length=362, Percent_Identity=25.414364640884, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71989531, Length=362, Percent_Identity=25.414364640884, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322632, Length=126, Percent_Identity=36.5079365079365, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6320595, Length=205, Percent_Identity=27.3170731707317, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI19922874, Length=430, Percent_Identity=22.7906976744186, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24640198, Length=446, Percent_Identity=22.6457399103139, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24640196, Length=446, Percent_Identity=22.6457399103139, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24640200, Length=446, Percent_Identity=22.6457399103139, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24668456, Length=359, Percent_Identity=26.1838440111421, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI62484254, Length=380, Percent_Identity=25.7894736842105, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24648211, Length=349, Percent_Identity=25.5014326647564, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47746; Mature: 47746

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTMQPSAPPHLESTKTIFSNSITKLVVFICWLAILADGYDLGIYGAVLPKLLEDNSWAL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEE
SPAHAGTIASYALFGMFIGAILVGTITDLIGRKWTLICCLALFSITMGLAAIALSPELFG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHH
LWRFIGGIGLGGVIPTASALTVEYSPKKRQSFIYALMFTGYPLGIVLGAILSMFMLEDFG
HHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
WRIMFGIGMIPLLLIPFIIRYLPESIQFLLSRNRQEEVDKILNRFQIEFHAKEKTHQAPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEECCHHHCCCHH
NIRKKNGFLTLFSKEYIKATLLFWITYIMGMFLIYGLNTWLPQMMRQAGYPLGSSLSFLL
HHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
MLNITAAIGALFAGAIADRIGAKIVISISYLMAAICIGLLTIKPSVTIIYLLIGLAGIGS
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCH
VGITQILNAYVTQYFPSHIRATSLGWGLGLGRVGAIAAPILIGIIMTMQYDLAWNFYLFS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAGLLAAISVFLIPAK
HHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNTMQPSAPPHLESTKTIFSNSITKLVVFICWLAILADGYDLGIYGAVLPKLLEDNSWAL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEE
SPAHAGTIASYALFGMFIGAILVGTITDLIGRKWTLICCLALFSITMGLAAIALSPELFG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHH
LWRFIGGIGLGGVIPTASALTVEYSPKKRQSFIYALMFTGYPLGIVLGAILSMFMLEDFG
HHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
WRIMFGIGMIPLLLIPFIIRYLPESIQFLLSRNRQEEVDKILNRFQIEFHAKEKTHQAPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEECCHHHCCCHH
NIRKKNGFLTLFSKEYIKATLLFWITYIMGMFLIYGLNTWLPQMMRQAGYPLGSSLSFLL
HHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
MLNITAAIGALFAGAIADRIGAKIVISISYLMAAICIGLLTIKPSVTIIYLLIGLAGIGS
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCH
VGITQILNAYVTQYFPSHIRATSLGWGLGLGRVGAIAAPILIGIIMTMQYDLAWNFYLFS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAGLLAAISVFLIPAK
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9294456 [H]