| Definition | Bacillus thuringiensis str. Al Hakam chromosome, complete genome. |
|---|---|
| Accession | NC_008600 |
| Length | 5,257,091 |
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The map label for this gene is gyrA [H]
Identifier: 118475784
GI number: 118475784
Start: 6593
End: 9067
Strand: Direct
Name: gyrA [H]
Synonym: BALH_0006
Alternate gene names: 118475784
Gene position: 6593-9067 (Clockwise)
Preceding gene: 118475783
Following gene: 118475786
Centisome position: 0.13
GC content: 36.61
Gene sequence:
>2475_bases TTGATGTCAGACAATCAACAACAAGCACGAATTCGAGAAATTAATATTAGCCATGAAATGCGTACCTCATTTTTAGATTA CGCAATGAGTGTTATCGTATCTCGTGCATTACCAGATGTTCGTGATGGATTAAAACCTGTGCATCGTAGGGTTTTATATG CGATGAATGATTTAGGAATTACGGCTGATAAAGCGTATAAAAAATCAGCACGTATTGTTGGTGAAGTAATCGGTAAGTAT CACCCTCATGGTGATTCAGCTGTTTATGAAACGATGGTACGTATGGCGCAAGATTTCAGTCAACGTTATATGCTTGTTGA TGGGCATGGTAACTTTGGATCTGTCGATGGAGATTCAGCGGCAGCAATGCGTTATACAGAAGCAAGAATGTCTAAAATCT CTATGGAATTAATACGTGATATTTCAAAAAATACAATTGATTATCAAGATAACTATGATGGTTCTGAAAGAGAGCCGATT GTGTTACCAGCGCGTTTTCCTAACTTACTAGTAAATGGTACGACAGGTATTGCAGTTGGTATGGCAACAAATATTCCGCC GCATCAACTTGGTGAAGTAATTGATGGCGTATTGGCATTAAGTCATAATCCCGATATTACTATTGCAGAATTAATGGAGT GCATTCCAGGACCAGATTTCCCGACGGCAGGTTTAATTTTAGGAAGAAGTGGTATTCGTAGAGCTTATGAAACAGGACGC GGGTCTATTATACTTCGTGCTAAAGTTGAAATTGAAGAGAAGTCAAATGGCAAACAATCTATTATCGTAACGGAACTACC TTATCAAGTGAATAAGGCGCGATTGATTGAAAAAATTGCAGAATTAGTTCGCGATAAGAAAATTGAAGGTATTACAGATT TACGTGATGAATCAGATCGAAATGGTATGCGTATTGTTATGGAAGTACGTCGTGATGCCAATGCTAATGTATTATTAAAT AACTTATATAAACATACAGCACTTCAAACAAGTTTTGGTATTAACATGCTGTCTCTTGTAAATGGAGAACCACAAGTACT GAATTTAAAACAAAATTTATATCATTACTTGGAACATCAAAAGGTAGTAATTCGTAGACGTACTGCTTATGAACTTGAAA AGGCAGAAGCACGTGCTCATATCTTAGAAGGATTACGAATTGCTTTAGACCATCTGGATGAAGTTATTACATTAATTCGT AGTTCGAAAACAGCGGAAATTGCAAAGCAAGGTTTAATGGAACGTTTTGGCTTAAGTGAAAAACAAGCGCAAGCTATTTT AGATATGCGTCTGCAACGCTTAACAGGATTAGAACGCGAAAAAATTGAACAAGAATATCAAGATTTAATGAAGTTAATCG CTGAATTAAAAGCAATCTTAGCAGATGAAGAAAAGGTTCTTGAGATTATTCGTGAAGAATTAACAGAAGTAAAAGAGCGC TTCAATGATAAGAGACGTACAGAAATTACAATTGGTGGTATGGAGTCTATTGAAGATGAAGACTTGATTCCAGAACAAAA CATCGCCATTACGTTAACTCATAATGGTTATATTAAGAGGTTGCCAGCTTCTACGTACAAAACACAGAACCGTGGTGGAC GTGGTGTGCAGGGAATGGGAACAAATGATGATGATTTCGTAGAGCATTTATTAACCACTTCTACGCATGATCATATTCTA TTCTTCACTAATAAGGGGAAAGTATACCGTACGAAAGGATATGAAATCCCAGAGTATAGTCGTACAGCGAAAGGTATACC TATTATTAACTTATTAGGTGTAGATAAGGGTGAATGGATTAACGCCATTATTCCAATTCGTGAATTTGGTGACGATGAAT TCTTATTCTTCACAACAAAACAAGGTATCTCTAAGAGAACACCACTTTCATCATTTGCGAATATACGTACAAATGGTTTA ATTGCAATTTCTCTTCGTGAAGAGGATGAAGTAATATCTGTACGTTTAACATCTGGTGATAAGGATATTATTGTAGGTAC AAGCAATGGTATGCTAATTCGTTTTAACGAGCAAGATGTACGTTCTATGGGACGTAATGCGGCTGGTGTAAAAGCAATTA CATTAGGTGAAGAAGATCAAGTTGTAGGTATGGAAATTGTCGAAGAGGATGTAAATGTTTTAATTGTAACGAAAAATGGT TATGGAAAACGTACGCCGATTGATGAATATCGCTTGCAAAGCCGTGGTGGTAAAGGTCTGAAGACTTGTAATATTACAGA TAAAAACGGTAAATTAGTAGCTGTTAAATCTGTAACAGGTGAAGAAGATATCATGTTAATTACAGCAGCAGGTGTTATTA TTCGTATGCCAGTTGATCAAATCTCTCAAATGGGACGTAATACACAAGGTGTTCGTCTAATTCGATTAGAGGATGAGCAA GAGGTAGCGACAGTAGCAAAAGCACAAAAAGATGATGAGGAAGAAACGAGCGAAGAGGTTTCTTCAGAAGAATAA
Upstream 100 bases:
>100_bases AACCTTGATATTTAAATGAGTAATGACAGGAATCTGAGTATTCCTGTCTTCTACATATAAATCAATGTATGTATAACGGA AATGTAAGAGGAGGTGCTCG
Downstream 100 bases:
>100_bases GAGGGGAGATATCTCCTCTCTTTATTTTTTTATAATAATACTTGCATGGGGAAGAGAAAGTCTATATAATAGGCAGAGTC AGCAAATGAGAGATACAAGT
Product: DNA gyrase subunit A
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 824; Mature: 824
Protein sequence:
>824_residues MMSDNQQQARIREINISHEMRTSFLDYAMSVIVSRALPDVRDGLKPVHRRVLYAMNDLGITADKAYKKSARIVGEVIGKY HPHGDSAVYETMVRMAQDFSQRYMLVDGHGNFGSVDGDSAAAMRYTEARMSKISMELIRDISKNTIDYQDNYDGSEREPI VLPARFPNLLVNGTTGIAVGMATNIPPHQLGEVIDGVLALSHNPDITIAELMECIPGPDFPTAGLILGRSGIRRAYETGR GSIILRAKVEIEEKSNGKQSIIVTELPYQVNKARLIEKIAELVRDKKIEGITDLRDESDRNGMRIVMEVRRDANANVLLN NLYKHTALQTSFGINMLSLVNGEPQVLNLKQNLYHYLEHQKVVIRRRTAYELEKAEARAHILEGLRIALDHLDEVITLIR SSKTAEIAKQGLMERFGLSEKQAQAILDMRLQRLTGLEREKIEQEYQDLMKLIAELKAILADEEKVLEIIREELTEVKER FNDKRRTEITIGGMESIEDEDLIPEQNIAITLTHNGYIKRLPASTYKTQNRGGRGVQGMGTNDDDFVEHLLTTSTHDHIL FFTNKGKVYRTKGYEIPEYSRTAKGIPIINLLGVDKGEWINAIIPIREFGDDEFLFFTTKQGISKRTPLSSFANIRTNGL IAISLREEDEVISVRLTSGDKDIIVGTSNGMLIRFNEQDVRSMGRNAAGVKAITLGEEDQVVGMEIVEEDVNVLIVTKNG YGKRTPIDEYRLQSRGGKGLKTCNITDKNGKLVAVKSVTGEEDIMLITAAGVIIRMPVDQISQMGRNTQGVRLIRLEDEQ EVATVAKAQKDDEEETSEEVSSEE
Sequences:
>Translated_824_residues MMSDNQQQARIREINISHEMRTSFLDYAMSVIVSRALPDVRDGLKPVHRRVLYAMNDLGITADKAYKKSARIVGEVIGKY HPHGDSAVYETMVRMAQDFSQRYMLVDGHGNFGSVDGDSAAAMRYTEARMSKISMELIRDISKNTIDYQDNYDGSEREPI VLPARFPNLLVNGTTGIAVGMATNIPPHQLGEVIDGVLALSHNPDITIAELMECIPGPDFPTAGLILGRSGIRRAYETGR GSIILRAKVEIEEKSNGKQSIIVTELPYQVNKARLIEKIAELVRDKKIEGITDLRDESDRNGMRIVMEVRRDANANVLLN NLYKHTALQTSFGINMLSLVNGEPQVLNLKQNLYHYLEHQKVVIRRRTAYELEKAEARAHILEGLRIALDHLDEVITLIR SSKTAEIAKQGLMERFGLSEKQAQAILDMRLQRLTGLEREKIEQEYQDLMKLIAELKAILADEEKVLEIIREELTEVKER FNDKRRTEITIGGMESIEDEDLIPEQNIAITLTHNGYIKRLPASTYKTQNRGGRGVQGMGTNDDDFVEHLLTTSTHDHIL FFTNKGKVYRTKGYEIPEYSRTAKGIPIINLLGVDKGEWINAIIPIREFGDDEFLFFTTKQGISKRTPLSSFANIRTNGL IAISLREEDEVISVRLTSGDKDIIVGTSNGMLIRFNEQDVRSMGRNAAGVKAITLGEEDQVVGMEIVEEDVNVLIVTKNG YGKRTPIDEYRLQSRGGKGLKTCNITDKNGKLVAVKSVTGEEDIMLITAAGVIIRMPVDQISQMGRNTQGVRLIRLEDEQ EVATVAKAQKDDEEETSEEVSSEE >Mature_824_residues MMSDNQQQARIREINISHEMRTSFLDYAMSVIVSRALPDVRDGLKPVHRRVLYAMNDLGITADKAYKKSARIVGEVIGKY HPHGDSAVYETMVRMAQDFSQRYMLVDGHGNFGSVDGDSAAAMRYTEARMSKISMELIRDISKNTIDYQDNYDGSEREPI VLPARFPNLLVNGTTGIAVGMATNIPPHQLGEVIDGVLALSHNPDITIAELMECIPGPDFPTAGLILGRSGIRRAYETGR GSIILRAKVEIEEKSNGKQSIIVTELPYQVNKARLIEKIAELVRDKKIEGITDLRDESDRNGMRIVMEVRRDANANVLLN NLYKHTALQTSFGINMLSLVNGEPQVLNLKQNLYHYLEHQKVVIRRRTAYELEKAEARAHILEGLRIALDHLDEVITLIR SSKTAEIAKQGLMERFGLSEKQAQAILDMRLQRLTGLEREKIEQEYQDLMKLIAELKAILADEEKVLEIIREELTEVKER FNDKRRTEITIGGMESIEDEDLIPEQNIAITLTHNGYIKRLPASTYKTQNRGGRGVQGMGTNDDDFVEHLLTTSTHDHIL FFTNKGKVYRTKGYEIPEYSRTAKGIPIINLLGVDKGEWINAIIPIREFGDDEFLFFTTKQGISKRTPLSSFANIRTNGL IAISLREEDEVISVRLTSGDKDIIVGTSNGMLIRFNEQDVRSMGRNAAGVKAITLGEEDQVVGMEIVEEDVNVLIVTKNG YGKRTPIDEYRLQSRGGKGLKTCNITDKNGKLVAVKSVTGEEDIMLITAAGVIIRMPVDQISQMGRNTQGVRLIRLEDEQ EVATVAKAQKDDEEETSEEVSSEE
Specific function: DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings [H]
COG id: COG0188
COG function: function code L; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the topoisomerase gyrA/parC subunit family [H]
Homologues:
Organism=Homo sapiens, GI19913408, Length=318, Percent_Identity=25.7861635220126, Blast_Score=79, Evalue=1e-14, Organism=Homo sapiens, GI19913406, Length=317, Percent_Identity=25.2365930599369, Blast_Score=74, Evalue=4e-13, Organism=Escherichia coli, GI1788562, Length=850, Percent_Identity=52.9411764705882, Blast_Score=877, Evalue=0.0, Organism=Escherichia coli, GI1789396, Length=695, Percent_Identity=37.1223021582734, Blast_Score=435, Evalue=1e-123, Organism=Caenorhabditis elegans, GI17535065, Length=212, Percent_Identity=30.6603773584906, Blast_Score=77, Evalue=5e-14, Organism=Caenorhabditis elegans, GI212645657, Length=211, Percent_Identity=30.3317535545024, Blast_Score=72, Evalue=9e-13, Organism=Saccharomyces cerevisiae, GI6324241, Length=200, Percent_Identity=28, Blast_Score=81, Evalue=7e-16, Organism=Drosophila melanogaster, GI17136538, Length=166, Percent_Identity=31.3253012048193, Blast_Score=73, Evalue=7e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR020899 - InterPro: IPR005743 - InterPro: IPR006691 - InterPro: IPR002205 - InterPro: IPR013758 - InterPro: IPR013757 - InterPro: IPR013760 [H]
Pfam domain/function: PF03989 DNA_gyraseA_C; PF00521 DNA_topoisoIV [H]
EC number: =5.99.1.3 [H]
Molecular weight: Translated: 92470; Mature: 92470
Theoretical pI: Translated: 5.48; Mature: 5.48
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 3.3 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 3.3 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MMSDNQQQARIREINISHEMRTSFLDYAMSVIVSRALPDVRDGLKPVHRRVLYAMNDLGI CCCCCCHHHHHEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC TADKAYKKSARIVGEVIGKYHPHGDSAVYETMVRMAQDFSQRYMLVDGHGNFGSVDGDSA CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCH AAMRYTEARMSKISMELIRDISKNTIDYQDNYDGSEREPIVLPARFPNLLVNGTTGIAVG HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCEEEE MATNIPPHQLGEVIDGVLALSHNPDITIAELMECIPGPDFPTAGLILGRSGIRRAYETGR EECCCCHHHHHHHHHHHHEECCCCCEEHHHHHHHCCCCCCCCCCEEECCHHHHHHHHCCC GSIILRAKVEIEEKSNGKQSIIVTELPYQVNKARLIEKIAELVRDKKIEGITDLRDESDR CCEEEEEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHCCCCCCC NGMRIVMEVRRDANANVLLNNLYKHTALQTSFGINMLSLVNGEPQVLNLKQNLYHYLEHQ CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEHHHHHHHHHHHH KVVIRRRTAYELEKAEARAHILEGLRIALDHLDEVITLIRSSKTAEIAKQGLMERFGLSE HHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCH KQAQAILDMRLQRLTGLEREKIEQEYQDLMKLIAELKAILADEEKVLEIIREELTEVKER HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH FNDKRRTEITIGGMESIEDEDLIPEQNIAITLTHNGYIKRLPASTYKTQNRGGRGVQGMG HCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCEEEECCCHHHCCCCCCCCCCCCCC TNDDDFVEHLLTTSTHDHILFFTNKGKVYRTKGYEIPEYSRTAKGIPIINLLGVDKGEWI CCHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCCCCCCCHHCCCCCEEEEEECCCCCCE NAIIPIREFGDDEFLFFTTKQGISKRTPLSSFANIRTNGLIAISLREEDEVISVRLTSGD EEEEEHHHCCCCCEEEEEECCCCCCCCCHHHHHHCCCCCEEEEEECCCCCEEEEEEECCC KDIIVGTSNGMLIRFNEQDVRSMGRNAAGVKAITLGEEDQVVGMEIVEEDVNVLIVTKNG CEEEEECCCCEEEEECHHHHHHCCCCCCCEEEEEECCCCCEEHHHHHCCCCCEEEEEECC YGKRTPIDEYRLQSRGGKGLKTCNITDKNGKLVAVKSVTGEEDIMLITAAGVIIRMPVDQ CCCCCCHHHHHHHCCCCCCCEEEEEECCCCCEEEEEECCCCCCEEEEEECCEEEECCHHH ISQMGRNTQGVRLIRLEDEQEVATVAKAQKDDEEETSEEVSSEE HHHCCCCCCCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHCCCC >Mature Secondary Structure MMSDNQQQARIREINISHEMRTSFLDYAMSVIVSRALPDVRDGLKPVHRRVLYAMNDLGI CCCCCCHHHHHEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC TADKAYKKSARIVGEVIGKYHPHGDSAVYETMVRMAQDFSQRYMLVDGHGNFGSVDGDSA CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCH AAMRYTEARMSKISMELIRDISKNTIDYQDNYDGSEREPIVLPARFPNLLVNGTTGIAVG HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCEEEE MATNIPPHQLGEVIDGVLALSHNPDITIAELMECIPGPDFPTAGLILGRSGIRRAYETGR EECCCCHHHHHHHHHHHHEECCCCCEEHHHHHHHCCCCCCCCCCEEECCHHHHHHHHCCC GSIILRAKVEIEEKSNGKQSIIVTELPYQVNKARLIEKIAELVRDKKIEGITDLRDESDR CCEEEEEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHCCCCCCC NGMRIVMEVRRDANANVLLNNLYKHTALQTSFGINMLSLVNGEPQVLNLKQNLYHYLEHQ CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEHHHHHHHHHHHH KVVIRRRTAYELEKAEARAHILEGLRIALDHLDEVITLIRSSKTAEIAKQGLMERFGLSE HHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCH KQAQAILDMRLQRLTGLEREKIEQEYQDLMKLIAELKAILADEEKVLEIIREELTEVKER HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH FNDKRRTEITIGGMESIEDEDLIPEQNIAITLTHNGYIKRLPASTYKTQNRGGRGVQGMG HCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCEEEECCCHHHCCCCCCCCCCCCCC TNDDDFVEHLLTTSTHDHILFFTNKGKVYRTKGYEIPEYSRTAKGIPIINLLGVDKGEWI CCHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCCCCCCCHHCCCCCEEEEEECCCCCCE NAIIPIREFGDDEFLFFTTKQGISKRTPLSSFANIRTNGLIAISLREEDEVISVRLTSGD EEEEEHHHCCCCCEEEEEECCCCCCCCCHHHHHHCCCCCEEEEEECCCCCEEEEEEECCC KDIIVGTSNGMLIRFNEQDVRSMGRNAAGVKAITLGEEDQVVGMEIVEEDVNVLIVTKNG CEEEEECCCCEEEEECHHHHHHCCCCCCCEEEEEECCCCCEEHHHHHCCCCCEEEEEECC YGKRTPIDEYRLQSRGGKGLKTCNITDKNGKLVAVKSVTGEEDIMLITAAGVIIRMPVDQ CCCCCCHHHHHHHCCCCCCCEEEEEECCCCCEEEEEECCCCCCEEEEEECCEEEECCHHH ISQMGRNTQGVRLIRLEDEQEVATVAKAQKDDEEETSEEVSSEE HHHCCCCCCCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 2987847; 7584024; 9384377 [H]