| Definition | Bacillus thuringiensis str. Al Hakam chromosome, complete genome. |
|---|---|
| Accession | NC_008600 |
| Length | 5,257,091 |
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The map label for this gene is gyrB [H]
Identifier: 118475783
GI number: 118475783
Start: 4570
End: 6507
Strand: Direct
Name: gyrB [H]
Synonym: BALH_0005
Alternate gene names: 118475783
Gene position: 4570-6507 (Clockwise)
Preceding gene: 118475782
Following gene: 118475784
Centisome position: 0.09
GC content: 37.0
Gene sequence:
>1938_bases GTGATCTTTGTGTCAATGGAACAAAAGCAAATGCAAGAAAATTCATATGATGAAAGTCAAATACAGGTACTTGAAGGACT AGAAGCAGTTCGAAAACGCCCTGGTATGTATATTGGATCTACAAGTGGAAAAGGACTTCACCATCTTGTATGGGAAATCG TTGATAATAGTATCGATGAAGCACTTGCAGGGTACTGTGACGAAATTAACGTTAGTATCGAAGAAGATAATAGTATTCGT GTAACAGATAATGGACGTGGTATTCCAGTTGGTATACAAGAAAAAATGGGACGTCCTGCTGTAGAAGTTATTATGACCGT TCTTCATGCTGGTGGTAAGTTTGGCGGCGGGGGTTATAAAGTTTCTGGTGGTTTGCATGGTGTTGGGGCATCTGTAGTAA ATGCTCTATCAACAGAACTAGAGGTATTTGTACATCGTGAAGGTAAAATCCATTATCAAAAATACGAAAGAGGTATTCCG GTTGCGGATTTAAAAGTCATTGGTGATACAGATCAAACGGGAACGATAACTCGATTTAAACCAGATCCAGAAATTTTTCA GGAAACAACAGTATACGAATTTGATACACTAGCAACTCGTATGCGTGAATTAGCATTTTTAAATCGTAATATTAAACTGA CGATTGAAGATAAACGTGAACATAAGCAAAAAAAAGAATTCCATTATGAAGGTGGAATTAAATCATATGTTGAGCATTTA AACCGCTCAAAACAACCAATCCATGAAGAGCCTGTATATGTAGAAGGATCAAAAGATGGTATTCAAGTTGAAGTTTCCTT ACAGTATAACGAAGGATATACAAATAATATTTACTCATTTACGAACAACATTCACACGTATGAAGGTGGAACACATGAAG TAGGGTTTAAAACAGCTTTAACTCGTGTGATTAACGATTATGGGCGTAAAAATAGTATTCTAAAAGATGCAGACAGTAAT TTAACTGGTGAGGACGTTCGTGAAGGTTTAACTGCAATTGTATCAATTAAACATCCAAATCCACAATTTGAAGGACAAAC GAAGACGAAACTTGGGAATAGTGAAGCGAGAACGATTACAGAGTCTGTGTTTTCAGAGGCATTTGAAAAGTTCTTACTAG AAAACCCGAACGTTGCACGAAAAATCGTAGAAAAAGGTACGATGGCAGCGCGTGCACGTGTTGCAGCGAAAAAAGCACGT GAATTGACACGTCGTAAGAGCGCGTTAGAAGTTTCGAGTTTACCTGGTAAATTAGCAGATTGCTCTTCAAAAGATCCAGC AATTAGTGAAATTTACATTGTAGAGGGTGACTCTGCCGGTGGATCAGCAAAGCAAGGGCGTGATCGTCACTTCCAAGCGA TTTTACCACTGAAAGGTAAAATTATTAACGTTGAAAAGGCAAGATTAGATAAAATCTTATCTAACGATGAAGTGCGTACA ATTATTACTGCAATTGGTACGAACATTGGCGGAGATTTTGATATTGAGAAAGCTCGTTATCATAAAGTTATTATTATGAC GGATGCCGACGTAGATGGTGCGCATATTCGTACCCTATTATTAACGTTCTTCTATCGTTATATGCGTCAAATTATTGAAC ATGGTTATATCTATATTGCACAGCCACCGTTGTTTAAAGTACAACAAGGTAAAAAAATTCAATATGCTTATAATGAGAAA GAGCTTGAAAAGATTTTAGCTGAATTACCAGCTCAACCTAAACCTGGAATCCAACGTTACAAAGGTTTAGGAGAAATGAA TCCAACTCAGCTTTGGGAAACAACAATGGACCCAGAAGTACGTTCATTACTTCAAGTTTCCCTTCAAGATGCAATTGAAG CAGATGAAACATTTGAAATTTTAATGGGGGATAAAGTAGAGCCACGTCGTAACTTTATCCAAGAAAATGCAAAATACGTG AAAAACCTTGATATTTAA
Upstream 100 bases:
>100_bases AACACGAAACATTAAAAGAAGCGAAAACAATTCATGTAACGAACGGCACGGTAGATTGTGAAATAGATAGGGCGTAATCC CTGTTTAAATGGAAAAGTAG
Downstream 100 bases:
>100_bases ATGAGTAATGACAGGAATCTGAGTATTCCTGTCTTCTACATATAAATCAATGTATGTATAACGGAAATGTAAGAGGAGGT GCTCGTTGATGTCAGACAAT
Product: DNA gyrase subunit B
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 645; Mature: 645
Protein sequence:
>645_residues MIFVSMEQKQMQENSYDESQIQVLEGLEAVRKRPGMYIGSTSGKGLHHLVWEIVDNSIDEALAGYCDEINVSIEEDNSIR VTDNGRGIPVGIQEKMGRPAVEVIMTVLHAGGKFGGGGYKVSGGLHGVGASVVNALSTELEVFVHREGKIHYQKYERGIP VADLKVIGDTDQTGTITRFKPDPEIFQETTVYEFDTLATRMRELAFLNRNIKLTIEDKREHKQKKEFHYEGGIKSYVEHL NRSKQPIHEEPVYVEGSKDGIQVEVSLQYNEGYTNNIYSFTNNIHTYEGGTHEVGFKTALTRVINDYGRKNSILKDADSN LTGEDVREGLTAIVSIKHPNPQFEGQTKTKLGNSEARTITESVFSEAFEKFLLENPNVARKIVEKGTMAARARVAAKKAR ELTRRKSALEVSSLPGKLADCSSKDPAISEIYIVEGDSAGGSAKQGRDRHFQAILPLKGKIINVEKARLDKILSNDEVRT IITAIGTNIGGDFDIEKARYHKVIIMTDADVDGAHIRTLLLTFFYRYMRQIIEHGYIYIAQPPLFKVQQGKKIQYAYNEK ELEKILAELPAQPKPGIQRYKGLGEMNPTQLWETTMDPEVRSLLQVSLQDAIEADETFEILMGDKVEPRRNFIQENAKYV KNLDI
Sequences:
>Translated_645_residues MIFVSMEQKQMQENSYDESQIQVLEGLEAVRKRPGMYIGSTSGKGLHHLVWEIVDNSIDEALAGYCDEINVSIEEDNSIR VTDNGRGIPVGIQEKMGRPAVEVIMTVLHAGGKFGGGGYKVSGGLHGVGASVVNALSTELEVFVHREGKIHYQKYERGIP VADLKVIGDTDQTGTITRFKPDPEIFQETTVYEFDTLATRMRELAFLNRNIKLTIEDKREHKQKKEFHYEGGIKSYVEHL NRSKQPIHEEPVYVEGSKDGIQVEVSLQYNEGYTNNIYSFTNNIHTYEGGTHEVGFKTALTRVINDYGRKNSILKDADSN LTGEDVREGLTAIVSIKHPNPQFEGQTKTKLGNSEARTITESVFSEAFEKFLLENPNVARKIVEKGTMAARARVAAKKAR ELTRRKSALEVSSLPGKLADCSSKDPAISEIYIVEGDSAGGSAKQGRDRHFQAILPLKGKIINVEKARLDKILSNDEVRT IITAIGTNIGGDFDIEKARYHKVIIMTDADVDGAHIRTLLLTFFYRYMRQIIEHGYIYIAQPPLFKVQQGKKIQYAYNEK ELEKILAELPAQPKPGIQRYKGLGEMNPTQLWETTMDPEVRSLLQVSLQDAIEADETFEILMGDKVEPRRNFIQENAKYV KNLDI >Mature_645_residues MIFVSMEQKQMQENSYDESQIQVLEGLEAVRKRPGMYIGSTSGKGLHHLVWEIVDNSIDEALAGYCDEINVSIEEDNSIR VTDNGRGIPVGIQEKMGRPAVEVIMTVLHAGGKFGGGGYKVSGGLHGVGASVVNALSTELEVFVHREGKIHYQKYERGIP VADLKVIGDTDQTGTITRFKPDPEIFQETTVYEFDTLATRMRELAFLNRNIKLTIEDKREHKQKKEFHYEGGIKSYVEHL NRSKQPIHEEPVYVEGSKDGIQVEVSLQYNEGYTNNIYSFTNNIHTYEGGTHEVGFKTALTRVINDYGRKNSILKDADSN LTGEDVREGLTAIVSIKHPNPQFEGQTKTKLGNSEARTITESVFSEAFEKFLLENPNVARKIVEKGTMAARARVAAKKAR ELTRRKSALEVSSLPGKLADCSSKDPAISEIYIVEGDSAGGSAKQGRDRHFQAILPLKGKIINVEKARLDKILSNDEVRT IITAIGTNIGGDFDIEKARYHKVIIMTDADVDGAHIRTLLLTFFYRYMRQIIEHGYIYIAQPPLFKVQQGKKIQYAYNEK ELEKILAELPAQPKPGIQRYKGLGEMNPTQLWETTMDPEVRSLLQVSLQDAIEADETFEILMGDKVEPRRNFIQENAKYV KNLDI
Specific function: DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings [H]
COG id: COG0187
COG function: function code L; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 Toprim domain [H]
Homologues:
Organism=Homo sapiens, GI19913406, Length=609, Percent_Identity=27.0935960591133, Blast_Score=136, Evalue=6e-32, Organism=Homo sapiens, GI19913408, Length=627, Percent_Identity=26.3157894736842, Blast_Score=131, Evalue=2e-30, Organism=Escherichia coli, GI48994957, Length=553, Percent_Identity=59.4936708860759, Blast_Score=652, Evalue=0.0, Organism=Escherichia coli, GI1789408, Length=628, Percent_Identity=39.6496815286624, Blast_Score=448, Evalue=1e-127, Organism=Caenorhabditis elegans, GI17535065, Length=618, Percent_Identity=25.0809061488673, Blast_Score=134, Evalue=1e-31, Organism=Caenorhabditis elegans, GI212645845, Length=541, Percent_Identity=25.3234750462107, Blast_Score=123, Evalue=3e-28, Organism=Caenorhabditis elegans, GI212645657, Length=227, Percent_Identity=26.431718061674, Blast_Score=73, Evalue=6e-13, Organism=Saccharomyces cerevisiae, GI6324241, Length=616, Percent_Identity=26.2987012987013, Blast_Score=108, Evalue=2e-24, Organism=Drosophila melanogaster, GI17136538, Length=620, Percent_Identity=25.1612903225806, Blast_Score=119, Evalue=7e-27,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003594 - InterPro: IPR011557 - InterPro: IPR020568 - InterPro: IPR014721 - InterPro: IPR001241 - InterPro: IPR013759 - InterPro: IPR002288 - InterPro: IPR013506 - InterPro: IPR013760 - InterPro: IPR018522 - InterPro: IPR006171 [H]
Pfam domain/function: PF00204 DNA_gyraseB; PF00986 DNA_gyraseB_C; PF02518 HATPase_c; PF01751 Toprim [H]
EC number: =5.99.1.3 [H]
Molecular weight: Translated: 72475; Mature: 72475
Theoretical pI: Translated: 6.39; Mature: 6.39
Prosite motif: PS00177 TOPOISOMERASE_II
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIFVSMEQKQMQENSYDESQIQVLEGLEAVRKRPGMYIGSTSGKGLHHLVWEIVDNSIDE CEEEECHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHH ALAGYCDEINVSIEEDNSIRVTDNGRGIPVGIQEKMGRPAVEVIMTVLHAGGKFGGGGYK HHHCCCCCCEEEEECCCEEEEECCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCEE VSGGLHGVGASVVNALSTELEVFVHREGKIHYQKYERGIPVADLKVIGDTDQTGTITRFK ECCCCCHHHHHHHHHHHHHEEEEEECCCCEEHHHHHCCCCEEEEEEECCCCCCCCEEEEC PDPEIFQETTVYEFDTLATRMRELAFLNRNIKLTIEDKREHKQKKEFHYEGGIKSYVEHL CCHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHH NRSKQPIHEEPVYVEGSKDGIQVEVSLQYNEGYTNNIYSFTNNIHTYEGGTHEVGFKTAL CCCCCCCCCCCEEEECCCCCEEEEEEEEECCCCCCCHHHHCCCEEECCCCCCCCHHHHHH TRVINDYGRKNSILKDADSNLTGEDVREGLTAIVSIKHPNPQFEGQTKTKLGNSEARTIT HHHHHHHCCCCCCHHCCCCCCCHHHHHCCCEEEEEEECCCCCCCCCHHHCCCCCHHHHHH ESVFSEAFEKFLLENPNVARKIVEKGTMAARARVAAKKARELTRRKSALEVSSLPGKLAD HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC CSSKDPAISEIYIVEGDSAGGSAKQGRDRHFQAILPLKGKIINVEKARLDKILSNDEVRT CCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCEEEECHHHHHHHHHCCCHHHH IITAIGTNIGGDFDIEKARYHKVIIMTDADVDGAHIRTLLLTFFYRYMRQIIEHGYIYIA HHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEE QPPLFKVQQGKKIQYAYNEKELEKILAELPAQPKPGIQRYKGLGEMNPTQLWETTMDPEV CCCCEECCCCCEEEEECCHHHHHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHCCCCHHH RSLLQVSLQDAIEADETFEILMGDKVEPRRNFIQENAKYVKNLDI HHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCC >Mature Secondary Structure MIFVSMEQKQMQENSYDESQIQVLEGLEAVRKRPGMYIGSTSGKGLHHLVWEIVDNSIDE CEEEECHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHH ALAGYCDEINVSIEEDNSIRVTDNGRGIPVGIQEKMGRPAVEVIMTVLHAGGKFGGGGYK HHHCCCCCCEEEEECCCEEEEECCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCEE VSGGLHGVGASVVNALSTELEVFVHREGKIHYQKYERGIPVADLKVIGDTDQTGTITRFK ECCCCCHHHHHHHHHHHHHEEEEEECCCCEEHHHHHCCCCEEEEEEECCCCCCCCEEEEC PDPEIFQETTVYEFDTLATRMRELAFLNRNIKLTIEDKREHKQKKEFHYEGGIKSYVEHL CCHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHH NRSKQPIHEEPVYVEGSKDGIQVEVSLQYNEGYTNNIYSFTNNIHTYEGGTHEVGFKTAL CCCCCCCCCCCEEEECCCCCEEEEEEEEECCCCCCCHHHHCCCEEECCCCCCCCHHHHHH TRVINDYGRKNSILKDADSNLTGEDVREGLTAIVSIKHPNPQFEGQTKTKLGNSEARTIT HHHHHHHCCCCCCHHCCCCCCCHHHHHCCCEEEEEEECCCCCCCCCHHHCCCCCHHHHHH ESVFSEAFEKFLLENPNVARKIVEKGTMAARARVAAKKARELTRRKSALEVSSLPGKLAD HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC CSSKDPAISEIYIVEGDSAGGSAKQGRDRHFQAILPLKGKIINVEKARLDKILSNDEVRT CCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCEEEECHHHHHHHHHCCCHHHH IITAIGTNIGGDFDIEKARYHKVIIMTDADVDGAHIRTLLLTFFYRYMRQIIEHGYIYIA HHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEE QPPLFKVQQGKKIQYAYNEKELEKILAELPAQPKPGIQRYKGLGEMNPTQLWETTMDPEV CCCCEECCCCCEEEEECCHHHHHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHCCCCHHH RSLLQVSLQDAIEADETFEILMGDKVEPRRNFIQENAKYVKNLDI HHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12721629; 10103241 [H]