| Definition | Shewanella sp. ANA-3 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_008577 |
| Length | 4,972,204 |
Click here to switch to the map view.
The map label for this gene is dkgB [H]
Identifier: 117922035
GI number: 117922035
Start: 4322843
End: 4323685
Strand: Direct
Name: dkgB [H]
Synonym: Shewana3_3599
Alternate gene names: 117922035
Gene position: 4322843-4323685 (Clockwise)
Preceding gene: 117922034
Following gene: 117922038
Centisome position: 86.94
GC content: 46.62
Gene sequence:
>843_bases ATGACTCAAACCAATGCGACAACATCTAACCAAGCGCCTCTGACAGCGATGCCGATGCTAGGCACAGGAACCTTCAGACT TAAAGATAACGCCGCTTTCGATGCCGTGTTGATGGCACTCGAAGAAGGTTCACGCCATATCGATACGGCGCAGATTTATG GCAATGAACAAGCGGTCGGGGATGCGATTAACACCTCAGGGATCCCACGTGAAGAACTGTTTATCACAACCAAAGTGTGG ACTGAAAACCTGACCAAGGAACGCTTTGAGACTAGCGTTATCGACAGCCTAACGGCGCTACAAACCAAGTATCTTGATTT GTTACTCATTCATTGGCCGTTGAACAGCGATGAGCCGAGTATGGTCGAGTATCTCTCAGAGCTAAAAGCAGTATTAGATA AAGGCCTGACTCGTCGCATTGGCGTATCAAACTTTACCAATGCACAACTCGCGCAAGCGATTGCCATCTTAGGCGAAGGC GTTATTTATACCAATCAAGTAGAAGTGCATCCCTATCTCATCAATCGCAAAGTGACGGATTTTTGCAGACAACACAATGT ATTAGTAACTGGGTATATGCCATTTGCCTATGGCGCAGTCTTGCAGGATGAAACCATAGTCAACTTAGCATCAGTGCATC AAGCCACTCCCGCACAAATTGTGTTGGCTTGGTTGCGACAATTAGGTTTTGCCACCATTCCCTCCTCAACCAAAAGAGAC AATGTTCGCAGCAACTTAGCGGCTGCAAGCATTAACTTAACGCCAGCAGAAATCGAGCAAATCAATCAACTGGATCGCAA TCATAGAGTTGCCAATCCTGACTTTGCCCCACATTGGGATTAG
Upstream 100 bases:
>100_bases GATTGTTGCAATAATAGCAAAAATCATTTGTGCTTTAGCCTCTTTATCGACAAAGCACGATCGGCGACAGTTGCCCCATC CACAGAATAAGGGGAAGAAT
Downstream 100 bases:
>100_bases CTCGAGCGCGCTTGAGTTAGCCTTTAGCTTCTAATGCCCAAGCGTCGATAAAGCTCTGATAATTGGCGATAAGCAAATCC GCCGCTTGGGCATAGTCCGG
Product: aldo/keto reductase
Products: NA
Alternate protein names: 2,5-DKG reductase B; 2,5-DKGR B; 25DKGR-B; AKR5D [H]
Number of amino acids: Translated: 280; Mature: 279
Protein sequence:
>280_residues MTQTNATTSNQAPLTAMPMLGTGTFRLKDNAAFDAVLMALEEGSRHIDTAQIYGNEQAVGDAINTSGIPREELFITTKVW TENLTKERFETSVIDSLTALQTKYLDLLLIHWPLNSDEPSMVEYLSELKAVLDKGLTRRIGVSNFTNAQLAQAIAILGEG VIYTNQVEVHPYLINRKVTDFCRQHNVLVTGYMPFAYGAVLQDETIVNLASVHQATPAQIVLAWLRQLGFATIPSSTKRD NVRSNLAAASINLTPAEIEQINQLDRNHRVANPDFAPHWD
Sequences:
>Translated_280_residues MTQTNATTSNQAPLTAMPMLGTGTFRLKDNAAFDAVLMALEEGSRHIDTAQIYGNEQAVGDAINTSGIPREELFITTKVW TENLTKERFETSVIDSLTALQTKYLDLLLIHWPLNSDEPSMVEYLSELKAVLDKGLTRRIGVSNFTNAQLAQAIAILGEG VIYTNQVEVHPYLINRKVTDFCRQHNVLVTGYMPFAYGAVLQDETIVNLASVHQATPAQIVLAWLRQLGFATIPSSTKRD NVRSNLAAASINLTPAEIEQINQLDRNHRVANPDFAPHWD >Mature_279_residues TQTNATTSNQAPLTAMPMLGTGTFRLKDNAAFDAVLMALEEGSRHIDTAQIYGNEQAVGDAINTSGIPREELFITTKVWT ENLTKERFETSVIDSLTALQTKYLDLLLIHWPLNSDEPSMVEYLSELKAVLDKGLTRRIGVSNFTNAQLAQAIAILGEGV IYTNQVEVHPYLINRKVTDFCRQHNVLVTGYMPFAYGAVLQDETIVNLASVHQATPAQIVLAWLRQLGFATIPSSTKRDN VRSNLAAASINLTPAEIEQINQLDRNHRVANPDFAPHWD
Specific function: Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG) [H]
COG id: COG0656
COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aldo/keto reductase family [H]
Homologues:
Organism=Homo sapiens, GI24497577, Length=291, Percent_Identity=31.6151202749141, Blast_Score=152, Evalue=3e-37, Organism=Homo sapiens, GI5174391, Length=291, Percent_Identity=31.6151202749141, Blast_Score=152, Evalue=3e-37, Organism=Homo sapiens, GI310109922, Length=276, Percent_Identity=33.695652173913, Blast_Score=149, Evalue=3e-36, Organism=Homo sapiens, GI5453543, Length=293, Percent_Identity=32.0819112627986, Blast_Score=144, Evalue=6e-35, Organism=Homo sapiens, GI310109920, Length=293, Percent_Identity=32.4232081911263, Blast_Score=144, Evalue=1e-34, Organism=Homo sapiens, GI45446745, Length=293, Percent_Identity=32.4232081911263, Blast_Score=143, Evalue=1e-34, Organism=Homo sapiens, GI4503285, Length=293, Percent_Identity=32.4232081911263, Blast_Score=143, Evalue=1e-34, Organism=Homo sapiens, GI24497585, Length=297, Percent_Identity=31.6498316498317, Blast_Score=141, Evalue=6e-34, Organism=Homo sapiens, GI24497583, Length=303, Percent_Identity=31.6831683168317, Blast_Score=141, Evalue=7e-34, Organism=Homo sapiens, GI93277124, Length=300, Percent_Identity=31, Blast_Score=140, Evalue=9e-34, Organism=Homo sapiens, GI223468663, Length=290, Percent_Identity=28.9655172413793, Blast_Score=139, Evalue=2e-33, Organism=Homo sapiens, GI5174695, Length=304, Percent_Identity=29.6052631578947, Blast_Score=132, Evalue=4e-31, Organism=Homo sapiens, GI291291012, Length=320, Percent_Identity=27.8125, Blast_Score=124, Evalue=1e-28, Organism=Homo sapiens, GI300116273, Length=284, Percent_Identity=29.5774647887324, Blast_Score=123, Evalue=2e-28, Organism=Homo sapiens, GI4502049, Length=289, Percent_Identity=30.4498269896194, Blast_Score=122, Evalue=5e-28, Organism=Homo sapiens, GI300116271, Length=286, Percent_Identity=28.3216783216783, Blast_Score=107, Evalue=9e-24, Organism=Homo sapiens, GI207028673, Length=109, Percent_Identity=38.5321100917431, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI310109926, Length=109, Percent_Identity=38.5321100917431, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI310109924, Length=158, Percent_Identity=32.9113924050633, Blast_Score=80, Evalue=1e-15, Organism=Escherichia coli, GI1786400, Length=266, Percent_Identity=50.7518796992481, Blast_Score=275, Evalue=3e-75, Organism=Escherichia coli, GI87082198, Length=264, Percent_Identity=34.469696969697, Blast_Score=155, Evalue=2e-39, Organism=Escherichia coli, GI1788081, Length=265, Percent_Identity=29.0566037735849, Blast_Score=104, Evalue=6e-24, Organism=Escherichia coli, GI1787674, Length=280, Percent_Identity=25, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI87081735, Length=299, Percent_Identity=27.7591973244147, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI48994888, Length=268, Percent_Identity=29.1044776119403, Blast_Score=65, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17537077, Length=289, Percent_Identity=33.2179930795848, Blast_Score=157, Evalue=5e-39, Organism=Caenorhabditis elegans, GI17550248, Length=292, Percent_Identity=33.5616438356164, Blast_Score=155, Evalue=2e-38, Organism=Caenorhabditis elegans, GI17537075, Length=290, Percent_Identity=32.4137931034483, Blast_Score=154, Evalue=6e-38, Organism=Caenorhabditis elegans, GI71998625, Length=260, Percent_Identity=31.9230769230769, Blast_Score=144, Evalue=4e-35, Organism=Caenorhabditis elegans, GI17537079, Length=296, Percent_Identity=29.7297297297297, Blast_Score=135, Evalue=3e-32, Organism=Caenorhabditis elegans, GI17566692, Length=284, Percent_Identity=29.5774647887324, Blast_Score=124, Evalue=4e-29, Organism=Caenorhabditis elegans, GI17562292, Length=282, Percent_Identity=31.2056737588652, Blast_Score=124, Evalue=7e-29, Organism=Caenorhabditis elegans, GI17564128, Length=297, Percent_Identity=29.6296296296296, Blast_Score=121, Evalue=5e-28, Organism=Caenorhabditis elegans, GI17552492, Length=271, Percent_Identity=28.7822878228782, Blast_Score=120, Evalue=1e-27, Organism=Caenorhabditis elegans, GI17538386, Length=268, Percent_Identity=30.5970149253731, Blast_Score=119, Evalue=1e-27, Organism=Caenorhabditis elegans, GI17561298, Length=266, Percent_Identity=28.1954887218045, Blast_Score=116, Evalue=1e-26, Organism=Caenorhabditis elegans, GI17561300, Length=262, Percent_Identity=27.8625954198473, Blast_Score=108, Evalue=4e-24, Organism=Saccharomyces cerevisiae, GI6324694, Length=293, Percent_Identity=33.7883959044369, Blast_Score=160, Evalue=1e-40, Organism=Saccharomyces cerevisiae, GI6320576, Length=282, Percent_Identity=31.9148936170213, Blast_Score=155, Evalue=5e-39, Organism=Saccharomyces cerevisiae, GI6322556, Length=259, Percent_Identity=26.2548262548263, Blast_Score=127, Evalue=3e-30, Organism=Saccharomyces cerevisiae, GI6321896, Length=304, Percent_Identity=25.6578947368421, Blast_Score=114, Evalue=3e-26, Organism=Saccharomyces cerevisiae, GI6319625, Length=293, Percent_Identity=32.4232081911263, Blast_Score=108, Evalue=1e-24, Organism=Saccharomyces cerevisiae, GI6320079, Length=285, Percent_Identity=28.4210526315789, Blast_Score=105, Evalue=7e-24, Organism=Drosophila melanogaster, GI24644950, Length=317, Percent_Identity=34.384858044164, Blast_Score=158, Evalue=4e-39, Organism=Drosophila melanogaster, GI221378297, Length=337, Percent_Identity=32.9376854599407, Blast_Score=152, Evalue=3e-37, Organism=Drosophila melanogaster, GI20129731, Length=278, Percent_Identity=32.3741007194245, Blast_Score=137, Evalue=7e-33, Organism=Drosophila melanogaster, GI24663317, Length=285, Percent_Identity=34.0350877192982, Blast_Score=137, Evalue=9e-33, Organism=Drosophila melanogaster, GI24662789, Length=290, Percent_Identity=33.1034482758621, Blast_Score=135, Evalue=4e-32, Organism=Drosophila melanogaster, GI24657054, Length=288, Percent_Identity=31.25, Blast_Score=134, Evalue=8e-32, Organism=Drosophila melanogaster, GI24662785, Length=286, Percent_Identity=32.8671328671329, Blast_Score=133, Evalue=1e-31, Organism=Drosophila melanogaster, GI45553081, Length=290, Percent_Identity=31.0344827586207, Blast_Score=132, Evalue=3e-31, Organism=Drosophila melanogaster, GI24662781, Length=285, Percent_Identity=32.6315789473684, Blast_Score=130, Evalue=8e-31, Organism=Drosophila melanogaster, GI21356425, Length=269, Percent_Identity=29.368029739777, Blast_Score=121, Evalue=5e-28, Organism=Drosophila melanogaster, GI281366140, Length=264, Percent_Identity=29.1666666666667, Blast_Score=109, Evalue=2e-24,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001395 - InterPro: IPR018170 - InterPro: IPR020471 - InterPro: IPR023210 [H]
Pfam domain/function: PF00248 Aldo_ket_red [H]
EC number: =1.1.1.274 [H]
Molecular weight: Translated: 31035; Mature: 30903
Theoretical pI: Translated: 5.11; Mature: 5.11
Prosite motif: PS00062 ALDOKETO_REDUCTASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 2.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTQTNATTSNQAPLTAMPMLGTGTFRLKDNAAFDAVLMALEEGSRHIDTAQIYGNEQAVG CCCCCCCCCCCCCCEEECEECCCEEEEECCCHHHHHHHHHHCCCCCCCHHEEECCCHHHC DAINTSGIPREELFITTKVWTENLTKERFETSVIDSLTALQTKYLDLLLIHWPLNSDEPS CCCCCCCCCHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCHH MVEYLSELKAVLDKGLTRRIGVSNFTNAQLAQAIAILGEGVIYTNQVEVHPYLINRKVTD HHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHCCCEEEECEEEECCEEECCHHHH FCRQHNVLVTGYMPFAYGAVLQDETIVNLASVHQATPAQIVLAWLRQLGFATIPSSTKRD HHHHCCEEEEECHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHH NVRSNLAAASINLTPAEIEQINQLDRNHRVANPDFAPHWD HHHHHHHHEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCC >Mature Secondary Structure TQTNATTSNQAPLTAMPMLGTGTFRLKDNAAFDAVLMALEEGSRHIDTAQIYGNEQAVG CCCCCCCCCCCCCEEECEECCCEEEEECCCHHHHHHHHHHCCCCCCCHHEEECCCHHHC DAINTSGIPREELFITTKVWTENLTKERFETSVIDSLTALQTKYLDLLLIHWPLNSDEPS CCCCCCCCCHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCHH MVEYLSELKAVLDKGLTRRIGVSNFTNAQLAQAIAILGEGVIYTNQVEVHPYLINRKVTD HHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHCCCEEEECEEEECCEEECCHHHH FCRQHNVLVTGYMPFAYGAVLQDETIVNLASVHQATPAQIVLAWLRQLGFATIPSSTKRD HHHHCCEEEEECHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHH NVRSNLAAASINLTPAEIEQINQLDRNHRVANPDFAPHWD HHHHHHHHEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796; 11108008 [H]