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The map label for this gene is gluQ [H]

Identifier: 117921842

GI number: 117921842

Start: 4073739

End: 4074638

Strand: Direct

Name: gluQ [H]

Synonym: Shewana3_3405

Alternate gene names: 117921842

Gene position: 4073739-4074638 (Clockwise)

Preceding gene: 117921841

Following gene: 117921843

Centisome position: 81.93

GC content: 53.67

Gene sequence:

>900_bases
ATGATGGCGACTCACTCTTCCAACATTTCCGCTTTACATCCCTATGTTGGCCGTTTTGCCCCTTCGCCCTCGGGCGCGCT
GCATTTTGGCTCACTGATCGCCGCCCTTGGCAGTTATCTGCGGGCACGCTCATTGGGGGGAAAGTGGTTAATTCGGGTTG
AAGATATTGATCCACCGAGGGAAGTCGCAGGCGCAGCCGATGATATTTTACGTACCTTAGAAGCCTACGGTTTCGAATGG
GATGACACAGTGCTGTACCAAAGTGCCCGCACCGAGGCCTATCAAGCCAAGCTCGACGAGTTACTCGCCGAAGATAACGC
CTACTTTTGCCAGTGCAGTCGTAAACAGATCCAAGCCATGGGCGGGATTTACGATGGACGCTGCCATCAGTTAGCCACGC
CGCATCAATCGGGCGCAATTCGCATTGTCAATCGACAACAAGTAGCCGAATTTAGCGATAACCTGATGGGAAAAGTCGTA
GTGGACCATGCCTTTGCCGCCGAAGATTTTATTATCAAACGCAGCGATGGCCTGTATGCCTATCAACTCGCTGTGGTGCT
GGATGATGCCTATCAAGGCATTACCGAAGTGGTACGGGGCTATGATTTAATCGAAGCCAGTTGTCGCCAATTAAGCCTGT
ATCAAACCTTTGGCCTAAGCGCGCCGCAGTGGTTGCATTTACCCTTGGCCTGCTTGACGCCGGGATTTAAGCTGTCGAAA
CAAAACCATGCGCAGGCTATCGACAAACAGCATCCGCAGGCAAGCCTTAATGCCGCCCTCGCCTTTTTAGGCCAAGCGCC
GGTGGAGCCGACAGCGGCGCCGCAAATGCTGGCCCAAGCGGTGGCGCAGTTTCAACTGTCGGCCATTCCGAAGCAGCGGG
AAATCTTGATAGCGCCTTAA

Upstream 100 bases:

>100_bases
GTTTGTGCGTCTCGCATGAACATCCTTCGTTTCACTTCGCTTTTTTGTTCGTATCCCCCTAAAATACAGCCACTTTGACT
GGTTATTCCTGCACATTCCT

Downstream 100 bases:

>100_bases
TCCCCGTGGGGCGAGTTGCGGCCAAAAAGCATCGTTTTAGCTGTGCTAAGTCGTGGCATAGCTCAAAAATCGCGATATAC
CCATCGGTGCGCAATTGGTA

Product: glutamyl-tRNA synthetase, class Ic

Products: NA

Alternate protein names: Glu-Q-RSs [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MMATHSSNISALHPYVGRFAPSPSGALHFGSLIAALGSYLRARSLGGKWLIRVEDIDPPREVAGAADDILRTLEAYGFEW
DDTVLYQSARTEAYQAKLDELLAEDNAYFCQCSRKQIQAMGGIYDGRCHQLATPHQSGAIRIVNRQQVAEFSDNLMGKVV
VDHAFAAEDFIIKRSDGLYAYQLAVVLDDAYQGITEVVRGYDLIEASCRQLSLYQTFGLSAPQWLHLPLACLTPGFKLSK
QNHAQAIDKQHPQASLNAALAFLGQAPVEPTAAPQMLAQAVAQFQLSAIPKQREILIAP

Sequences:

>Translated_299_residues
MMATHSSNISALHPYVGRFAPSPSGALHFGSLIAALGSYLRARSLGGKWLIRVEDIDPPREVAGAADDILRTLEAYGFEW
DDTVLYQSARTEAYQAKLDELLAEDNAYFCQCSRKQIQAMGGIYDGRCHQLATPHQSGAIRIVNRQQVAEFSDNLMGKVV
VDHAFAAEDFIIKRSDGLYAYQLAVVLDDAYQGITEVVRGYDLIEASCRQLSLYQTFGLSAPQWLHLPLACLTPGFKLSK
QNHAQAIDKQHPQASLNAALAFLGQAPVEPTAAPQMLAQAVAQFQLSAIPKQREILIAP
>Mature_299_residues
MMATHSSNISALHPYVGRFAPSPSGALHFGSLIAALGSYLRARSLGGKWLIRVEDIDPPREVAGAADDILRTLEAYGFEW
DDTVLYQSARTEAYQAKLDELLAEDNAYFCQCSRKQIQAMGGIYDGRCHQLATPHQSGAIRIVNRQQVAEFSDNLMGKVV
VDHAFAAEDFIIKRSDGLYAYQLAVVLDDAYQGITEVVRGYDLIEASCRQLSLYQTFGLSAPQWLHLPLACLTPGFKLSK
QNHAQAIDKQHPQASLNAALAFLGQAPVEPTAAPQMLAQAVAQFQLSAIPKQREILIAP

Specific function: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble positi

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily [H]

Homologues:

Organism=Homo sapiens, GI134288884, Length=249, Percent_Identity=34.5381526104418, Blast_Score=127, Evalue=2e-29,
Organism=Escherichia coli, GI226510925, Length=280, Percent_Identity=55, Blast_Score=307, Evalue=6e-85,
Organism=Escherichia coli, GI1788743, Length=258, Percent_Identity=33.7209302325581, Blast_Score=143, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71993394, Length=312, Percent_Identity=30.4487179487179, Blast_Score=121, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6324540, Length=290, Percent_Identity=31.3793103448276, Blast_Score=140, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24665321, Length=306, Percent_Identity=33.0065359477124, Blast_Score=137, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022380
- InterPro:   IPR000924
- InterPro:   IPR020058
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c [H]

EC number: NA

Molecular weight: Translated: 32758; Mature: 32758

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMATHSSNISALHPYVGRFAPSPSGALHFGSLIAALGSYLRARSLGGKWLIRVEDIDPPR
CCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHH
EVAGAADDILRTLEAYGFEWDDTVLYQSARTEAYQAKLDELLAEDNAYFCQCSRKQIQAM
HHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHH
GGIYDGRCHQLATPHQSGAIRIVNRQQVAEFSDNLMGKVVVDHAFAAEDFIIKRSDGLYA
CCCCCCCHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEE
YQLAVVLDDAYQGITEVVRGYDLIEASCRQLSLYQTFGLSAPQWLHLPLACLTPGFKLSK
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHCCCCCCCC
QNHAQAIDKQHPQASLNAALAFLGQAPVEPTAAPQMLAQAVAQFQLSAIPKQREILIAP
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECC
>Mature Secondary Structure
MMATHSSNISALHPYVGRFAPSPSGALHFGSLIAALGSYLRARSLGGKWLIRVEDIDPPR
CCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHH
EVAGAADDILRTLEAYGFEWDDTVLYQSARTEAYQAKLDELLAEDNAYFCQCSRKQIQAM
HHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHH
GGIYDGRCHQLATPHQSGAIRIVNRQQVAEFSDNLMGKVVVDHAFAAEDFIIKRSDGLYA
CCCCCCCHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEE
YQLAVVLDDAYQGITEVVRGYDLIEASCRQLSLYQTFGLSAPQWLHLPLACLTPGFKLSK
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHCCCCCCCC
QNHAQAIDKQHPQASLNAALAFLGQAPVEPTAAPQMLAQAVAQFQLSAIPKQREILIAP
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]