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The map label for this gene is sdaC [H]

Identifier: 117921803

GI number: 117921803

Start: 4034331

End: 4035623

Strand: Reverse

Name: sdaC [H]

Synonym: Shewana3_3365

Alternate gene names: 117921803

Gene position: 4035623-4034331 (Counterclockwise)

Preceding gene: 117921804

Following gene: 117921801

Centisome position: 81.16

GC content: 49.19

Gene sequence:

>1293_bases
ATGCAAAAAGATGCGATCAGTGTTCTCGAAACACCTCAAAGCACGCAAGAAAGCACAACAAGACACTTACCATGGACGCG
CCAAGACACCACTTGGATGCTAAGTTTATTCGGCACCGCTGTGGGGGCGGGCATTCTATTTCTTCCTATCAATGCGGGCA
TGGGCGGTTTTTGGCCCTTAGTCTTGATGGCCATTATCATCGGCCCAATGACCTATCTTGCCCACCGCGGCCTGTCACGC
TTCGTATGTTCATCGAGTATTCCCGGCAGTGACATTACCCAAGTCGTTGAAGAACACTTTGGAATTGGCGCGGGCAAGGC
GATTACATTGCTGTATTTCTTAGCGATTTATCCCATTGTGTTGATCTACGGTGTGGGGATCACTAACACAGTCGACAGTT
TTATCGTCAACCAGTTGGGCATGGCCTCACCACCACGTTTCCTGCTGTCAGGCGTGTTGATTTTCGGCATGATGGCCGTG
ATGGTTGCTGGTGAGCAATTTATGCTGAAGGTGACTCAGCTGCTGGTCTATCCGCTGGTGGGCATTTTGGCTTTTATGTC
CATCTATTTGATCCCGGAGTGGAAAATGGATGCGCTGCAAGTCGTGCCAGACACCGGCGCCTTTTTAGGTACTGTATGGT
TAACCATTCCTGTGTTGGTGTTTGCCTTCAACCATTCTCCGGCGATTTCGCAATTTTCGGTTTCCCTTAAGCGTGACCAT
GGTGTCAACGCGGCCCGTAAGGCCGATGTGATCCTGCGTAATACCTCGATGATGTTAGTCGGCTTTGTGATGTTATTCGT
GTTCTCCTGCGTGTTGTCACTGTCGCCAGAACAGTTGGCCGAAGCGAAGGCGAAGAACCTGCCGATTTTATCTTACCTTG
CGAACGTGCATGACAGTGGTTTTGTCAGCTATTTCGGGCCTTTTATCGCATTTGTGGCGATTGTGTCTTCTTTCTTTGGC
CATTACATGGGCGCGACTGAGGGCATGAAGGGCATTATCGTTAAGCAGCTGCGCTCAAGTAACAAACAAATCAGTGAGAA
CAAGCTGAACAAGTTTATCTTAGTGTTTATGTTTGCCACGATTTGGGCCGTTGCGATTAAAAACCCAAGTATTTTGGGGA
TGATTGAGGCGCTGGGCGGCCCGATTATTGCGGCAATTTTGTACTTAATGCCAATGTATGCCGTGTACAAAGTGCCGGCT
CTGAAGGCTTACCGTAACCGCATCAGCAACGTGTTTGTGATTATTGCGGGCCTGCTGGCGATGACGGCTATTCTGTTTGG
CTTGTTAAGCTAA

Upstream 100 bases:

>100_bases
TTTCATTACTTAAAATGGTGTTAGATCAACTTTTGCTTAAGCTTTTTCGCTATCCTTACGCCGAATTTTTTATGCGGTAT
CACCGTAAGGTAATTTTAAT

Downstream 100 bases:

>100_bases
GCTTGGAATTCAAAGCGGTTTGAAACGAAAGGATCGGGTGATGCCCGATCCTTTTTTTATTACTTTTCTTCGTACATCAG
ATAGTAGCTTTGCTTCATCC

Product: serine transporter

Products: Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MQKDAISVLETPQSTQESTTRHLPWTRQDTTWMLSLFGTAVGAGILFLPINAGMGGFWPLVLMAIIIGPMTYLAHRGLSR
FVCSSSIPGSDITQVVEEHFGIGAGKAITLLYFLAIYPIVLIYGVGITNTVDSFIVNQLGMASPPRFLLSGVLIFGMMAV
MVAGEQFMLKVTQLLVYPLVGILAFMSIYLIPEWKMDALQVVPDTGAFLGTVWLTIPVLVFAFNHSPAISQFSVSLKRDH
GVNAARKADVILRNTSMMLVGFVMLFVFSCVLSLSPEQLAEAKAKNLPILSYLANVHDSGFVSYFGPFIAFVAIVSSFFG
HYMGATEGMKGIIVKQLRSSNKQISENKLNKFILVFMFATIWAVAIKNPSILGMIEALGGPIIAAILYLMPMYAVYKVPA
LKAYRNRISNVFVIIAGLLAMTAILFGLLS

Sequences:

>Translated_430_residues
MQKDAISVLETPQSTQESTTRHLPWTRQDTTWMLSLFGTAVGAGILFLPINAGMGGFWPLVLMAIIIGPMTYLAHRGLSR
FVCSSSIPGSDITQVVEEHFGIGAGKAITLLYFLAIYPIVLIYGVGITNTVDSFIVNQLGMASPPRFLLSGVLIFGMMAV
MVAGEQFMLKVTQLLVYPLVGILAFMSIYLIPEWKMDALQVVPDTGAFLGTVWLTIPVLVFAFNHSPAISQFSVSLKRDH
GVNAARKADVILRNTSMMLVGFVMLFVFSCVLSLSPEQLAEAKAKNLPILSYLANVHDSGFVSYFGPFIAFVAIVSSFFG
HYMGATEGMKGIIVKQLRSSNKQISENKLNKFILVFMFATIWAVAIKNPSILGMIEALGGPIIAAILYLMPMYAVYKVPA
LKAYRNRISNVFVIIAGLLAMTAILFGLLS
>Mature_430_residues
MQKDAISVLETPQSTQESTTRHLPWTRQDTTWMLSLFGTAVGAGILFLPINAGMGGFWPLVLMAIIIGPMTYLAHRGLSR
FVCSSSIPGSDITQVVEEHFGIGAGKAITLLYFLAIYPIVLIYGVGITNTVDSFIVNQLGMASPPRFLLSGVLIFGMMAV
MVAGEQFMLKVTQLLVYPLVGILAFMSIYLIPEWKMDALQVVPDTGAFLGTVWLTIPVLVFAFNHSPAISQFSVSLKRDH
GVNAARKADVILRNTSMMLVGFVMLFVFSCVLSLSPEQLAEAKAKNLPILSYLANVHDSGFVSYFGPFIAFVAIVSSFFG
HYMGATEGMKGIIVKQLRSSNKQISENKLNKFILVFMFATIWAVAIKNPSILGMIEALGGPIIAAILYLMPMYAVYKVPA
LKAYRNRISNVFVIIAGLLAMTAILFGLLS

Specific function: Involved in the import of serine into the cell [H]

COG id: COG0814

COG function: function code E; Amino acid permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789160, Length=429, Percent_Identity=55.4778554778555, Blast_Score=458, Evalue=1e-130,
Organism=Escherichia coli, GI1789504, Length=443, Percent_Identity=43.5665914221219, Blast_Score=345, Evalue=4e-96,
Organism=Escherichia coli, GI1789211, Length=408, Percent_Identity=35.0490196078431, Blast_Score=241, Evalue=7e-65,
Organism=Escherichia coli, GI1789961, Length=399, Percent_Identity=27.0676691729323, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI145693183, Length=434, Percent_Identity=25.5760368663594, Blast_Score=128, Evalue=7e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004694
- InterPro:   IPR018227 [H]

Pfam domain/function: PF03222 Trp_Tyr_perm [H]

EC number: NA

Molecular weight: Translated: 46891; Mature: 46891

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]