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The map label for this gene is hlyB [H]

Identifier: 117921611

GI number: 117921611

Start: 3813267

End: 3814892

Strand: Direct

Name: hlyB [H]

Synonym: Shewana3_3173

Alternate gene names: 117921611

Gene position: 3813267-3814892 (Clockwise)

Preceding gene: 117921610

Following gene: 117921612

Centisome position: 76.69

GC content: 46.8

Gene sequence:

>1626_bases
ATGAATGGTCTACAAATAAAACAAAAAATGTTTATCGGCATTCTCGTGCCGCTCCTAATGCTACTGACTATCGGTTTTAT
CGCCATCAATATGATGGGAAAAATCGAATATGGTGTCGAACGCATCTATAACGACCGAGTCGTCCCCCTTGATGATCTCA
AAGTGATTGCCGATAAATATGCCGTGGATGTGATTGATGCGGTGAACAAGGCTAATGCCGGCGGCTTTACGGCTTCTCAG
GCCATCAATGCCCTTGAAAGTGCTAAATCCACAGTCAATCAACGCTGGCAGAAATATCTATCAACTGAGCTTACCAAGGA
AGAATCGCAACTCGCGCAGCAAGCTGAGCGTTTATTTACTCCCGCCAATGAACAAATAGAGCAGTTAATCACGTATCTTC
GGGGATTAAATGGCGATGTGGTGCATCAACTGAACGACAAAATATTACCTCTGTATAACGCCATCGATCCCATCAGCGGT
AAAGTCTCCGAGCTGATTGATCTGCAAATTAAGATCGCCGGTCAGGAGAAAGATGCCGTAAACGGTATTTACCAATCCTC
TATTTCTATTTTTATCACCCTTGCGGGTATCGCCATGCTGATAAGCATAGTGATTGGGCTCTGGGTGAATCGCAGCGTGA
TGAATCCGATCCGTGATATTGTTGAAAATCTTAAGACGATACGACAAGACTCTGATCTCACCGTTAAGTTTAAAACTTTC
AACGACGATGAACTCGGGCAGATCTCCACTAGCCTGACCCAAGTGATTGAACATCTGCGGGGCATTTTGCACTCAATTGC
CGAAGCCGCAAATACGGTCAATAGTTCAGCCACTGAACTAAGTAGTTTTACCCAAGCAACCAATAAACGCATGCAGCAGC
AACAGGCGGAAACCGAACAAACGGCAACGGCCATGAATGAAATGACGGCAACTGTTGCCGAAGTGGCTCAAAGCGCCGCA
GCGGCTGCAGATTCTGCCAAGGATGCGGATAGTTATGCCGCCAACGGTAATCATATTGTGATGCAATCCATCACCAGCAT
GTCGCAACTTTCGGAGCAAATTCAGAAAACGGCGCAAGTGATTGGCTTTTTATCCAATGAAAGCCAAAACATAGGTCGGG
TATTGGATGTGATCAAAAGCATTGCCGAACAAACCAATCTACTGGCATTAAATGCGGCGATTGAAGCCGCCCGCGCCGGA
GAGCAAGGTCGAGGCTTTGCGGTGGTCGCCGATGAAGTCAGGACATTGGCGCAGCGCACCCAAAAATCGACTCAAGAGAT
TGAAGCTATGATCGCCACTCTACAACAAGGTGTAAAAGAAGCGGTGAATGCAATGGAGGTCGGTATCAATCAAGTCGATG
ATGCCAACGATAAGGCGAATCAAGCTGGCCAAGCGTTAAAAGAGATTGTCGCCTCCGTCGACAATATCACCGAGTTAAAT
ACTCATATCGCCACGGCTGCCGAGGAGCAAAGCAGCGTAGCCGAGAGCATCAACCGCAGCATTATCGCCATCAGTGATAT
TGCCGAACACTCCACTAACTCAGCCTTAGAGTTGAGTGAATCCGTACTTAATCTCACAAAACTTGCCAACAGTATGCGTA
ATCAGGTGAGTGCATTTAGGCTTTAA

Upstream 100 bases:

>100_bases
TCACCTTCCTTAAATTTGCTATAACTATTCATACAGACTCATCATAGGGACAGCTCGAGCTCTGCCTAAAGGACTCCCTT
GTTTCACCGAGGAAATCCAT

Downstream 100 bases:

>100_bases
CACTTCTTCGTAGGCACAGGTTCACTGTGCCTACGACTTCATTACTCAATACCTATCTTCACAAAAATCACACCTAACAG
TTTTAGGTGTGATTTTTATT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MNGLQIKQKMFIGILVPLLMLLTIGFIAINMMGKIEYGVERIYNDRVVPLDDLKVIADKYAVDVIDAVNKANAGGFTASQ
AINALESAKSTVNQRWQKYLSTELTKEESQLAQQAERLFTPANEQIEQLITYLRGLNGDVVHQLNDKILPLYNAIDPISG
KVSELIDLQIKIAGQEKDAVNGIYQSSISIFITLAGIAMLISIVIGLWVNRSVMNPIRDIVENLKTIRQDSDLTVKFKTF
NDDELGQISTSLTQVIEHLRGILHSIAEAANTVNSSATELSSFTQATNKRMQQQQAETEQTATAMNEMTATVAEVAQSAA
AAADSAKDADSYAANGNHIVMQSITSMSQLSEQIQKTAQVIGFLSNESQNIGRVLDVIKSIAEQTNLLALNAAIEAARAG
EQGRGFAVVADEVRTLAQRTQKSTQEIEAMIATLQQGVKEAVNAMEVGINQVDDANDKANQAGQALKEIVASVDNITELN
THIATAAEEQSSVAESINRSIIAISDIAEHSTNSALELSESVLNLTKLANSMRNQVSAFRL

Sequences:

>Translated_541_residues
MNGLQIKQKMFIGILVPLLMLLTIGFIAINMMGKIEYGVERIYNDRVVPLDDLKVIADKYAVDVIDAVNKANAGGFTASQ
AINALESAKSTVNQRWQKYLSTELTKEESQLAQQAERLFTPANEQIEQLITYLRGLNGDVVHQLNDKILPLYNAIDPISG
KVSELIDLQIKIAGQEKDAVNGIYQSSISIFITLAGIAMLISIVIGLWVNRSVMNPIRDIVENLKTIRQDSDLTVKFKTF
NDDELGQISTSLTQVIEHLRGILHSIAEAANTVNSSATELSSFTQATNKRMQQQQAETEQTATAMNEMTATVAEVAQSAA
AAADSAKDADSYAANGNHIVMQSITSMSQLSEQIQKTAQVIGFLSNESQNIGRVLDVIKSIAEQTNLLALNAAIEAARAG
EQGRGFAVVADEVRTLAQRTQKSTQEIEAMIATLQQGVKEAVNAMEVGINQVDDANDKANQAGQALKEIVASVDNITELN
THIATAAEEQSSVAESINRSIIAISDIAEHSTNSALELSESVLNLTKLANSMRNQVSAFRL
>Mature_541_residues
MNGLQIKQKMFIGILVPLLMLLTIGFIAINMMGKIEYGVERIYNDRVVPLDDLKVIADKYAVDVIDAVNKANAGGFTASQ
AINALESAKSTVNQRWQKYLSTELTKEESQLAQQAERLFTPANEQIEQLITYLRGLNGDVVHQLNDKILPLYNAIDPISG
KVSELIDLQIKIAGQEKDAVNGIYQSSISIFITLAGIAMLISIVIGLWVNRSVMNPIRDIVENLKTIRQDSDLTVKFKTF
NDDELGQISTSLTQVIEHLRGILHSIAEAANTVNSSATELSSFTQATNKRMQQQQAETEQTATAMNEMTATVAEVAQSAA
AAADSAKDADSYAANGNHIVMQSITSMSQLSEQIQKTAQVIGFLSNESQNIGRVLDVIKSIAEQTNLLALNAAIEAARAG
EQGRGFAVVADEVRTLAQRTQKSTQEIEAMIATLQQGVKEAVNAMEVGINQVDDANDKANQAGQALKEIVASVDNITELN
THIATAAEEQSSVAESINRSIIAISDIAEHSTNSALELSESVLNLTKLANSMRNQVSAFRL

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=499, Percent_Identity=28.0561122244489, Blast_Score=158, Evalue=7e-40,
Organism=Escherichia coli, GI2367378, Length=374, Percent_Identity=31.0160427807487, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1788194, Length=359, Percent_Identity=30.3621169916435, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1788195, Length=302, Percent_Identity=30.4635761589404, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1789453, Length=259, Percent_Identity=30.8880308880309, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58660; Mature: 58660

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGLQIKQKMFIGILVPLLMLLTIGFIAINMMGKIEYGVERIYNDRVVPLDDLKVIADKY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AVDVIDAVNKANAGGFTASQAINALESAKSTVNQRWQKYLSTELTKEESQLAQQAERLFT
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PANEQIEQLITYLRGLNGDVVHQLNDKILPLYNAIDPISGKVSELIDLQIKIAGQEKDAV
CCHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHEEEECCCHHHH
NGIYQSSISIFITLAGIAMLISIVIGLWVNRSVMNPIRDIVENLKTIRQDSDLTVKFKTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
NDDELGQISTSLTQVIEHLRGILHSIAEAANTVNSSATELSSFTQATNKRMQQQQAETEQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TATAMNEMTATVAEVAQSAAAAADSAKDADSYAANGNHIVMQSITSMSQLSEQIQKTAQV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHH
IGFLSNESQNIGRVLDVIKSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLAQRT
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHH
QKSTQEIEAMIATLQQGVKEAVNAMEVGINQVDDANDKANQAGQALKEIVASVDNITELN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
THIATAAEEQSSVAESINRSIIAISDIAEHSTNSALELSESVLNLTKLANSMRNQVSAFR
HHHHHHHHHHHHHHHHHCCCEEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
L
C
>Mature Secondary Structure
MNGLQIKQKMFIGILVPLLMLLTIGFIAINMMGKIEYGVERIYNDRVVPLDDLKVIADKY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AVDVIDAVNKANAGGFTASQAINALESAKSTVNQRWQKYLSTELTKEESQLAQQAERLFT
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PANEQIEQLITYLRGLNGDVVHQLNDKILPLYNAIDPISGKVSELIDLQIKIAGQEKDAV
CCHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHEEEECCCHHHH
NGIYQSSISIFITLAGIAMLISIVIGLWVNRSVMNPIRDIVENLKTIRQDSDLTVKFKTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
NDDELGQISTSLTQVIEHLRGILHSIAEAANTVNSSATELSSFTQATNKRMQQQQAETEQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TATAMNEMTATVAEVAQSAAAAADSAKDADSYAANGNHIVMQSITSMSQLSEQIQKTAQV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHH
IGFLSNESQNIGRVLDVIKSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLAQRT
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHH
QKSTQEIEAMIATLQQGVKEAVNAMEVGINQVDDANDKANQAGQALKEIVASVDNITELN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
THIATAAEEQSSVAESINRSIIAISDIAEHSTNSALELSESVLNLTKLANSMRNQVSAFR
HHHHHHHHHHHHHHHHHCCCEEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]