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The map label for this gene is purE [H]

Identifier: 117921593

GI number: 117921593

Start: 3784624

End: 3785115

Strand: Direct

Name: purE [H]

Synonym: Shewana3_3155

Alternate gene names: 117921593

Gene position: 3784624-3785115 (Clockwise)

Preceding gene: 117921592

Following gene: 117921594

Centisome position: 76.12

GC content: 51.42

Gene sequence:

>492_bases
ATGCAAGCCCTTGTTGCTGTTGTTATGGGTTCTAAGAGTGATTGGCCCACAATGGAAGCCGCCGCTGAGATCATGGATAA
ACTGCAAGTGCCTTACCATGTTGAAGTCGTATCTGCCCATAGAACGCCAGATAAACTGATGGAGTTTGCAGCCGGAGCCG
CTGACCGTGGTTTTAAAATTATTATCGGTGGTGCGGGCGGTGCTGCTCACTTACCCGGTATGATTGCCTCAAAAACTCGC
TTACCCGTATTAGGTGTACCAGTACAAAGCAAAGCGCTGTCGGGCATGGATAGCTTACTGTCTATCGTGCAGATGCCAAA
AGGCATTGCCGTTGGCACTCTGGCCATCGGAACCGCAGGTGCCTTTAACGCCGGTCTACTCGCCTGCCAAATCTTAGCCA
ATAACGATGCTGAACTTGCCGCACGTTTAGAAGCCTTTAGAGAAGAACAAACCCGCGCAGTGCTGGACAATCCCGACCCG
AGGGAAGCCTAA

Upstream 100 bases:

>100_bases
CATGATGCTCCCGGCTCTGATAGGGGTTGCGGACATCGACTGTACCCAGACCTGATACAAGGTCAAAATATAATTAAAAT
TAGTGAGTTAAGGAGTTATC

Downstream 100 bases:

>100_bases
TGACTCAAGCAAGTGCAAAACCTAAGGTTTGGGTATTAGGTAATGGCCAACTTGGCGCCATGCTGACCCACGCGGGCGAG
CCTTTGGCGATTGATGTTCG

Product: phosphoribosylaminoimidazole carboxylase, catalytic subunit

Products: NA

Alternate protein names: N5-CAIR mutase; 5-(carboxyamino)imidazole ribonucleotide mutase [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MQALVAVVMGSKSDWPTMEAAAEIMDKLQVPYHVEVVSAHRTPDKLMEFAAGAADRGFKIIIGGAGGAAHLPGMIASKTR
LPVLGVPVQSKALSGMDSLLSIVQMPKGIAVGTLAIGTAGAFNAGLLACQILANNDAELAARLEAFREEQTRAVLDNPDP
REA

Sequences:

>Translated_163_residues
MQALVAVVMGSKSDWPTMEAAAEIMDKLQVPYHVEVVSAHRTPDKLMEFAAGAADRGFKIIIGGAGGAAHLPGMIASKTR
LPVLGVPVQSKALSGMDSLLSIVQMPKGIAVGTLAIGTAGAFNAGLLACQILANNDAELAARLEAFREEQTRAVLDNPDP
REA
>Mature_163_residues
MQALVAVVMGSKSDWPTMEAAAEIMDKLQVPYHVEVVSAHRTPDKLMEFAAGAADRGFKIIIGGAGGAAHLPGMIASKTR
LPVLGVPVQSKALSGMDSLLSIVQMPKGIAVGTLAIGTAGAFNAGLLACQILANNDAELAARLEAFREEQTRAVLDNPDP
REA

Specific function: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) [H]

COG id: COG0041

COG function: function code F; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AIR carboxylase family [H]

Homologues:

Organism=Escherichia coli, GI1786734, Length=161, Percent_Identity=70.8074534161491, Blast_Score=195, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6324702, Length=155, Percent_Identity=49.0322580645161, Blast_Score=152, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000031 [H]

Pfam domain/function: PF00731 AIRC [H]

EC number: =5.4.99.18 [H]

Molecular weight: Translated: 16960; Mature: 16960

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQALVAVVMGSKSDWPTMEAAAEIMDKLQVPYHVEVVSAHRTPDKLMEFAAGAADRGFKI
CCHHEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHCCCCCCCCEE
IIGGAGGAAHLPGMIASKTRLPVLGVPVQSKALSGMDSLLSIVQMPKGIAVGTLAIGTAG
EEECCCCHHHCCCHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
AFNAGLLACQILANNDAELAARLEAFREEQTRAVLDNPDPREA
CCCHHHHEEHEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MQALVAVVMGSKSDWPTMEAAAEIMDKLQVPYHVEVVSAHRTPDKLMEFAAGAADRGFKI
CCHHEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHCCCCCCCCEE
IIGGAGGAAHLPGMIASKTRLPVLGVPVQSKALSGMDSLLSIVQMPKGIAVGTLAIGTAG
EEECCCCHHHCCCHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
AFNAGLLACQILANNDAELAARLEAFREEQTRAVLDNPDPREA
CCCHHHHEEHEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA