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The map label for this gene is rppH [H]

Identifier: 117921482

GI number: 117921482

Start: 3647913

End: 3648437

Strand: Reverse

Name: rppH [H]

Synonym: Shewana3_3043

Alternate gene names: 117921482

Gene position: 3648437-3647913 (Counterclockwise)

Preceding gene: 117921485

Following gene: 117921481

Centisome position: 73.38

GC content: 46.67

Gene sequence:

>525_bases
GTGATTGATAGCGACGGCTTTCGCGCAAATGTGGGCATAATAATTTGTAATAGATACGGCCAAGTCATGTGGGCCAGACG
ATTCGGACAACATTCATGGCAATTTCCTCAGGGCGGTGTCGATGATGGTGAATCGGCCGAAGAGGCGATGTACCGTGAAT
TGTATGAGGAAGTAGGCTTAAGACCCGAGCATGTCACTATATTAACCTCGACCCGTTCTTGGTTAAGATACCGCTTGCCC
AAGCGTTTAGTGAGACAGGACAGCAAGCCTGTGTGCATTGGCCAAAAACAAAAATGGTTTCTGTTACAACTCAAAAGCCA
AGATAGTGCGATTAATTTAAGTTCCTCAGGCCACCCTGAGTTTGACGATTGGCGTTGGGTAAGTTATTGGTATCCCGTGC
GGCAGGTTGTCTCATTTAAGCGTGATGTTTATCGTAAGGTAATGAAAGAGTTTGCGGTAACGGCATTGTCATTCCAAACC
CAGGAAATTCCGAGGAAGCGGGTAAGACAAAGAACAACGGGCTGA

Upstream 100 bases:

>100_bases
AAGGTATTTATCCAAAAAATAGCTGTAAATAGAGGTTTGCTGAGAGACTGGCTTTGTGAAACAATCGGTTTATTAAAAGT
TATCCTTATTTGGAGTCCAT

Downstream 100 bases:

>100_bases
TTTTCAAAAGAGGATTGAAAACAGTGTTAAATACGCTCAGGGATATTACTCAAGCTGTGGCGTCCGCCCACAGCTTAGAA
ACCGCATTAGAAGTCCTAGT

Product: dinucleoside polyphosphate hydrolase

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase [H]

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MIDSDGFRANVGIIICNRYGQVMWARRFGQHSWQFPQGGVDDGESAEEAMYRELYEEVGLRPEHVTILTSTRSWLRYRLP
KRLVRQDSKPVCIGQKQKWFLLQLKSQDSAINLSSSGHPEFDDWRWVSYWYPVRQVVSFKRDVYRKVMKEFAVTALSFQT
QEIPRKRVRQRTTG

Sequences:

>Translated_174_residues
MIDSDGFRANVGIIICNRYGQVMWARRFGQHSWQFPQGGVDDGESAEEAMYRELYEEVGLRPEHVTILTSTRSWLRYRLP
KRLVRQDSKPVCIGQKQKWFLLQLKSQDSAINLSSSGHPEFDDWRWVSYWYPVRQVVSFKRDVYRKVMKEFAVTALSFQT
QEIPRKRVRQRTTG
>Mature_174_residues
MIDSDGFRANVGIIICNRYGQVMWARRFGQHSWQFPQGGVDDGESAEEAMYRELYEEVGLRPEHVTILTSTRSWLRYRLP
KRLVRQDSKPVCIGQKQKWFLLQLKSQDSAINLSSSGHPEFDDWRWVSYWYPVRQVVSFKRDVYRKVMKEFAVTALSFQT
QEIPRKRVRQRTTG

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1789194, Length=159, Percent_Identity=77.3584905660377, Blast_Score=265, Evalue=2e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 20609; Mature: 20609

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDSDGFRANVGIIICNRYGQVMWARRFGQHSWQFPQGGVDDGESAEEAMYRELYEEVGL
CCCCCCCEEEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
RPEHVTILTSTRSWLRYRLPKRLVRQDSKPVCIGQKQKWFLLQLKSQDSAINLSSSGHPE
CCCEEEEEECHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEEECCCCEEECCCCCCCC
FDDWRWVSYWYPVRQVVSFKRDVYRKVMKEFAVTALSFQTQEIPRKRVRQRTTG
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIDSDGFRANVGIIICNRYGQVMWARRFGQHSWQFPQGGVDDGESAEEAMYRELYEEVGL
CCCCCCCEEEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
RPEHVTILTSTRSWLRYRLPKRLVRQDSKPVCIGQKQKWFLLQLKSQDSAINLSSSGHPE
CCCEEEEEECHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEEECCCCEEECCCCCCCC
FDDWRWVSYWYPVRQVVSFKRDVYRKVMKEFAVTALSFQTQEIPRKRVRQRTTG
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA