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The map label for this gene is nhaR [H]

Identifier: 117921475

GI number: 117921475

Start: 3640469

End: 3641377

Strand: Reverse

Name: nhaR [H]

Synonym: Shewana3_3036

Alternate gene names: 117921475

Gene position: 3641377-3640469 (Counterclockwise)

Preceding gene: 117921476

Following gene: 117921474

Centisome position: 73.23

GC content: 47.52

Gene sequence:

>909_bases
ATGCTGCATCTTAATTACAACCATCTGTATTATTTCTGGATGATCAAGAAGAAGGGCTCTGTGGCCAAGGCGGCCGAAGC
CCTTTGTCTGACGCCTCAAACCATCACGGGGCAAATTCGCGCCCTCGAAGATCGTCTTAATGGTAGTCTATTCAAACGTG
TCGGACGCAATTTAGAGGCGACGGAACTCGGTGAGCTGGTATTTCGCTACGCCGATAAGATGTTTTCCCTCAGTTATGAG
ATGCTCGATTTACTCAACTATCAAAAAGATGATGCCATTTTATTTGAAGTGGGGATTGCCGATGCCTTGTCTAAAGCCTT
GGCGAGTCGCGTATTGCTTTCTGTTGTGCCCAATGACGGCTCCATGCACCTTGCTTGTTATGAAGCGACCCACGAAAGTT
TAATGACCCGTTTACGCGAGCATAAACTGGATATGATCCTCTCGGACTGTGCGGGTGAGTCATTGAAATATCCTGAGATT
TTATCGAAAAAACTGGGTGAGTGTGGCGTGAGCTTTTTCTCCGCCGAAACCTACAGCGCCGATTTCCCCGCTTGTTTAGA
GCAAGGGCAATTGCTGATCCCCGGTCGTAGAACATCGCTTGGGCAACAATTATACCGTTGGTTTGATGAGCAAAATCTTA
AGGTCAGTATCTTAGGTGAGTTTGATGATGCGGCGATGATGAAGGCCTTTGGCTACCTTAAACGCGGGATCTTCGTCACG
CCGTCGGTCTATCCGCAAGAAGTGATTTCCCACGGCATGCATTTGCTCGGCGAAACCTTAGATGTTAAGGAAGAATACCA
TGTGATGTTTGCCGAGCGGATGATCCAACATCCAGCGGTGAAACGTTTATTAGAGACGGATTTCAGTGATTTATTTGCCG
GATTAGACAGCCAAGTTCAGCGGTGCTAA

Upstream 100 bases:

>100_bases
AATAGCGCAATCGACTCATCATTTGTTAAGCTGAGTCACTGCGATCCGACATACCGCAGCCCTTGAGGCTGCGGTATCCA
TTAGAGGAAGCTCATTGGCG

Downstream 100 bases:

>100_bases
ACCGAGTTTCAATACGGCTTGCATCGACACTCTACGGCGTGAACTGGTAAACTAGGGCGAAATTTGTTTTGGGAGAATTA
ACTTGGAGTTAATGAACATT

Product: transcriptional activator NhaR

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MLHLNYNHLYYFWMIKKKGSVAKAAEALCLTPQTITGQIRALEDRLNGSLFKRVGRNLEATELGELVFRYADKMFSLSYE
MLDLLNYQKDDAILFEVGIADALSKALASRVLLSVVPNDGSMHLACYEATHESLMTRLREHKLDMILSDCAGESLKYPEI
LSKKLGECGVSFFSAETYSADFPACLEQGQLLIPGRRTSLGQQLYRWFDEQNLKVSILGEFDDAAMMKAFGYLKRGIFVT
PSVYPQEVISHGMHLLGETLDVKEEYHVMFAERMIQHPAVKRLLETDFSDLFAGLDSQVQRC

Sequences:

>Translated_302_residues
MLHLNYNHLYYFWMIKKKGSVAKAAEALCLTPQTITGQIRALEDRLNGSLFKRVGRNLEATELGELVFRYADKMFSLSYE
MLDLLNYQKDDAILFEVGIADALSKALASRVLLSVVPNDGSMHLACYEATHESLMTRLREHKLDMILSDCAGESLKYPEI
LSKKLGECGVSFFSAETYSADFPACLEQGQLLIPGRRTSLGQQLYRWFDEQNLKVSILGEFDDAAMMKAFGYLKRGIFVT
PSVYPQEVISHGMHLLGETLDVKEEYHVMFAERMIQHPAVKRLLETDFSDLFAGLDSQVQRC
>Mature_302_residues
MLHLNYNHLYYFWMIKKKGSVAKAAEALCLTPQTITGQIRALEDRLNGSLFKRVGRNLEATELGELVFRYADKMFSLSYE
MLDLLNYQKDDAILFEVGIADALSKALASRVLLSVVPNDGSMHLACYEATHESLMTRLREHKLDMILSDCAGESLKYPEI
LSKKLGECGVSFFSAETYSADFPACLEQGQLLIPGRRTSLGQQLYRWFDEQNLKVSILGEFDDAAMMKAFGYLKRGIFVT
PSVYPQEVISHGMHLLGETLDVKEEYHVMFAERMIQHPAVKRLLETDFSDLFAGLDSQVQRC

Specific function: Plays a role in the positive regulation of nhaA (Probable) [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=295, Percent_Identity=58.3050847457627, Blast_Score=353, Evalue=6e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34249; Mature: 34249

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHLNYNHLYYFWMIKKKGSVAKAAEALCLTPQTITGQIRALEDRLNGSLFKRVGRNLEA
CEEEEECCEEEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHCCCCCH
TELGELVFRYADKMFSLSYEMLDLLNYQKDDAILFEVGIADALSKALASRVLLSVVPNDG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCC
SMHLACYEATHESLMTRLREHKLDMILSDCAGESLKYPEILSKKLGECGVSFFSAETYSA
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHCCCCCCC
DFPACLEQGQLLIPGRRTSLGQQLYRWFDEQNLKVSILGEFDDAAMMKAFGYLKRGIFVT
CCHHHHHCCCEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCEEEC
PSVYPQEVISHGMHLLGETLDVKEEYHVMFAERMIQHPAVKRLLETDFSDLFAGLDSQVQ
CCCCHHHHHHHHHHHHCCHHCHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHH
RC
CC
>Mature Secondary Structure
MLHLNYNHLYYFWMIKKKGSVAKAAEALCLTPQTITGQIRALEDRLNGSLFKRVGRNLEA
CEEEEECCEEEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHCCCCCH
TELGELVFRYADKMFSLSYEMLDLLNYQKDDAILFEVGIADALSKALASRVLLSVVPNDG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCC
SMHLACYEATHESLMTRLREHKLDMILSDCAGESLKYPEILSKKLGECGVSFFSAETYSA
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHCCCCCCC
DFPACLEQGQLLIPGRRTSLGQQLYRWFDEQNLKVSILGEFDDAAMMKAFGYLKRGIFVT
CCHHHHHCCCEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCEEEC
PSVYPQEVISHGMHLLGETLDVKEEYHVMFAERMIQHPAVKRLLETDFSDLFAGLDSQVQ
CCCCHHHHHHHHHHHHCCHHCHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHH
RC
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8231807; 9457888; 10952301 [H]