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The map label for this gene is pheA [H]

Identifier: 117921446

GI number: 117921446

Start: 3612019

End: 3614022

Strand: Direct

Name: pheA [H]

Synonym: Shewana3_3007

Alternate gene names: 117921446

Gene position: 3612019-3614022 (Clockwise)

Preceding gene: 117921445

Following gene: 117921458

Centisome position: 72.64

GC content: 50.35

Gene sequence:

>2004_bases
ATGCAAAAACCACAGCCTTTAAATCAAACGCGAGAACAAATTACTCACCTCGACAATGAGCTTCTCTCGTTACTCGCCGA
ACGTCGACGCCTAAGCCTTGAAGTGGCCCGCAGTAAAGAAGTTGATGTGAGACCCATTCGCGACACCCAAAGGGAAAAAG
AACTGCTGGCAAGATTAGTCACCGCTGGCCGAGAAAAAGGTTTAGATGCCCATTATGTAATATCACTGTATCAAAGCATT
ATCGAAGACTCAGTCCTCAACCAGCAGGCTTATCTCCACGGCCGCGCCAATCCAGAAACGCAAAAACAACAATACTGTAT
CGCCTACCTTGGCGCCCGCGGCTCCTACTCTTACCTGGCCGCCTCTCGCTATTGCCAACGTCGTCAGGTTGAGATGCTCG
ATTTAGGCTGCCAAAGTTTCGATGAGATTGTCCAAGCCGTTGAGTCAGGCCACGCCGACTATGGCTTTTTGCCGATTGAA
AACACTTCGTCCGGCTCGATCAACGAAGTATATGATGTGCTGCAACACACCAGCCTCTCCATCGTTGGCGAGACAACTAT
CGAAGTCAGCCATTGTTTGTTGGGCAAACCGGGCAGCAAACTGAGTGATATCAAAACCGTCTACGCCCATCCGCAGCCTA
TCAGTCAGTGCAGCCGTTATCTGAGCCAGCACAAAGACTTAAGACTGGAATATTGCTCAAGCAGCGCCGAAGCAATGGAG
AAGGTCAATCAATCTGCCGACAATAGCGCCGCAGCAATTGGTAGCACTGAAGGTGGCGCGCTGTACCAACTCGAGTCGAT
TGAGTCGGGTCTTGCGAACCAAAAAATTAACCAGAGTCGCTTTATCGTGGTGGCTCGAAAAGCCGTAGCCGTACCCGAGC
AACTGCCTGCCAAAACCACCCTGATCATGGCCACTGGCCAAAAGGCTGGCGCCTTGGTTGAAGCCCTATTGGTGCTCAAG
GCGCATCAGCTGAATATGAGTAAACTCGAGTCTCGCCCTATTCCTGGCACGCCGTGGGAAGAAATGTTCTATCTGGATAT
CGATGCCAATATCTCCAGCGAAGCCATGCAGCAAGGGCTCAAGCAGCTCGAGAGGATCACGCGTTTTATCAAAGTATTAG
GATGTTACCCCTGTGAAACCGTCAAACCGACACAACTCAGTAATAGCCAATTACTTATCGAGCCGAGCACCTCAAAAGCG
CAGGTGATAAGTACGGTGAGCCTTGACCCATCGCCCTATCGCTTCAGTAAGGCGTACAAGGCGCAGGCGAGTGAAATTCA
CTGCGGCCCCTTTACCATTGGTGCAGGCCATATTGGAGCCATTGCCAAGATCACGCTGAGCAAAAGCCTGCTGCAGCTAG
AGTCGTCACAGGCCGCCTTATCCGCCTTTGAGCGCAGAGTAAAACAGCTAAAAGAGGCGGGTTTTCAAGCGGTAATTTTA
GACGGATGCCACTCACTCGTCTCGGCCGAAGCTATCATCCCTAAGCTGCGCCAAACCCTGCATCAGTATGATTTGCTTTG
TGTTATCGCCATCGAACAGGCGACGGATATGCCATTGGCGACTGGTCATGCCGACATGTTGTTCTTAACGGGCAAACAAA
TGTTTAATCAGGCTCTGCTGGCTCAGGCAGGCACCTTGCCGATCCCGCTATTCCTCGAACGCAACGATATGGCAAGTTAT
GAGGAGTTTATGGCGGCAACGGAGGCGATTTTAAGTCAAGGTAACCAACAGCTTATCCTATGTGACTCAGGCATTCGTAC
CTATAACAATGCCAACTTACCCACCTTGGATTTAGCAAGCCTTATCCAAATTAAGGCCAATAGTCATCTCCCCATAGTAA
TTAACCCTTGTTATGCCATCAGCGAAGATACGCTGCCACTGCAAACTCAAGGAATTAAACAGCTGAAAGCCGATGGCCTA
GTGCTGAATTGCTCCCTCGAAGAAGATAAAGCACATGACGCATTAGCGCTGATGGCCGAGGTCGTGAGGGAGTTATATCG
CTAA

Upstream 100 bases:

>100_bases
CGGATTTACTGTGTAAAAACGAAAGTAAAAATCCAAAGCCTCCCACTGGGAGGCTTTTTCGTCTTAAACGCTCGATAATA
CGGTGGCAAATGAGGTCAGA

Downstream 100 bases:

>100_bases
TTTGAGCATATAAGGATACTAAGGAACATACAGCCACGAATATCGTGGCTGTCTTGTTTAGAACTTAGGCTTCATAGCTG
TGGATTTAGGACTGTAGATT

Product: chorismate mutase / prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 667; Mature: 667

Protein sequence:

>667_residues
MQKPQPLNQTREQITHLDNELLSLLAERRRLSLEVARSKEVDVRPIRDTQREKELLARLVTAGREKGLDAHYVISLYQSI
IEDSVLNQQAYLHGRANPETQKQQYCIAYLGARGSYSYLAASRYCQRRQVEMLDLGCQSFDEIVQAVESGHADYGFLPIE
NTSSGSINEVYDVLQHTSLSIVGETTIEVSHCLLGKPGSKLSDIKTVYAHPQPISQCSRYLSQHKDLRLEYCSSSAEAME
KVNQSADNSAAAIGSTEGGALYQLESIESGLANQKINQSRFIVVARKAVAVPEQLPAKTTLIMATGQKAGALVEALLVLK
AHQLNMSKLESRPIPGTPWEEMFYLDIDANISSEAMQQGLKQLERITRFIKVLGCYPCETVKPTQLSNSQLLIEPSTSKA
QVISTVSLDPSPYRFSKAYKAQASEIHCGPFTIGAGHIGAIAKITLSKSLLQLESSQAALSAFERRVKQLKEAGFQAVIL
DGCHSLVSAEAIIPKLRQTLHQYDLLCVIAIEQATDMPLATGHADMLFLTGKQMFNQALLAQAGTLPIPLFLERNDMASY
EEFMAATEAILSQGNQQLILCDSGIRTYNNANLPTLDLASLIQIKANSHLPIVINPCYAISEDTLPLQTQGIKQLKADGL
VLNCSLEEDKAHDALALMAEVVRELYR

Sequences:

>Translated_667_residues
MQKPQPLNQTREQITHLDNELLSLLAERRRLSLEVARSKEVDVRPIRDTQREKELLARLVTAGREKGLDAHYVISLYQSI
IEDSVLNQQAYLHGRANPETQKQQYCIAYLGARGSYSYLAASRYCQRRQVEMLDLGCQSFDEIVQAVESGHADYGFLPIE
NTSSGSINEVYDVLQHTSLSIVGETTIEVSHCLLGKPGSKLSDIKTVYAHPQPISQCSRYLSQHKDLRLEYCSSSAEAME
KVNQSADNSAAAIGSTEGGALYQLESIESGLANQKINQSRFIVVARKAVAVPEQLPAKTTLIMATGQKAGALVEALLVLK
AHQLNMSKLESRPIPGTPWEEMFYLDIDANISSEAMQQGLKQLERITRFIKVLGCYPCETVKPTQLSNSQLLIEPSTSKA
QVISTVSLDPSPYRFSKAYKAQASEIHCGPFTIGAGHIGAIAKITLSKSLLQLESSQAALSAFERRVKQLKEAGFQAVIL
DGCHSLVSAEAIIPKLRQTLHQYDLLCVIAIEQATDMPLATGHADMLFLTGKQMFNQALLAQAGTLPIPLFLERNDMASY
EEFMAATEAILSQGNQQLILCDSGIRTYNNANLPTLDLASLIQIKANSHLPIVINPCYAISEDTLPLQTQGIKQLKADGL
VLNCSLEEDKAHDALALMAEVVRELYR
>Mature_667_residues
MQKPQPLNQTREQITHLDNELLSLLAERRRLSLEVARSKEVDVRPIRDTQREKELLARLVTAGREKGLDAHYVISLYQSI
IEDSVLNQQAYLHGRANPETQKQQYCIAYLGARGSYSYLAASRYCQRRQVEMLDLGCQSFDEIVQAVESGHADYGFLPIE
NTSSGSINEVYDVLQHTSLSIVGETTIEVSHCLLGKPGSKLSDIKTVYAHPQPISQCSRYLSQHKDLRLEYCSSSAEAME
KVNQSADNSAAAIGSTEGGALYQLESIESGLANQKINQSRFIVVARKAVAVPEQLPAKTTLIMATGQKAGALVEALLVLK
AHQLNMSKLESRPIPGTPWEEMFYLDIDANISSEAMQQGLKQLERITRFIKVLGCYPCETVKPTQLSNSQLLIEPSTSKA
QVISTVSLDPSPYRFSKAYKAQASEIHCGPFTIGAGHIGAIAKITLSKSLLQLESSQAALSAFERRVKQLKEAGFQAVIL
DGCHSLVSAEAIIPKLRQTLHQYDLLCVIAIEQATDMPLATGHADMLFLTGKQMFNQALLAQAGTLPIPLFLERNDMASY
EEFMAATEAILSQGNQQLILCDSGIRTYNNANLPTLDLASLIQIKANSHLPIVINPCYAISEDTLPLQTQGIKQLKADGL
VLNCSLEEDKAHDALALMAEVVRELYR

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=386, Percent_Identity=55.1813471502591, Blast_Score=433, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6324013, Length=294, Percent_Identity=25.5102040816327, Blast_Score=77, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 73459; Mature: 73459

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKPQPLNQTREQITHLDNELLSLLAERRRLSLEVARSKEVDVRPIRDTQREKELLARLV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
TAGREKGLDAHYVISLYQSIIEDSVLNQQAYLHGRANPETQKQQYCIAYLGARGSYSYLA
HHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHEECCCCCCHHHHHEEHHEECCCCCHHHHH
ASRYCQRRQVEMLDLGCQSFDEIVQAVESGHADYGFLPIENTSSGSINEVYDVLQHTSLS
HHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHCCEE
IVGETTIEVSHCLLGKPGSKLSDIKTVYAHPQPISQCSRYLSQHKDLRLEYCSSSAEAME
EEECCHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHCCHHHHHH
KVNQSADNSAAAIGSTEGGALYQLESIESGLANQKINQSRFIVVARKAVAVPEQLPAKTT
HHHCCCCCCCEECCCCCCCCEEEHHHHHHCHHCCCCCCCEEEEEEHHHHCCCCCCCCCEE
LIMATGQKAGALVEALLVLKAHQLNMSKLESRPIPGTPWEEMFYLDIDANISSEAMQQGL
EEEECCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHEEEEEECCCCCHHHHHHHH
KQLERITRFIKVLGCYPCETVKPTQLSNSQLLIEPSTSKAQVISTVSLDPSPYRFSKAYK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEEECCCCCCHHHHHHH
AQASEIHCGPFTIGAGHIGAIAKITLSKSLLQLESSQAALSAFERRVKQLKEAGFQAVIL
CCCCEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEH
DGCHSLVSAEAIIPKLRQTLHQYDLLCVIAIEQATDMPLATGHADMLFLTGKQMFNQALL
HHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCEECCCCCEEEEECHHHHHHHHH
AQAGTLPIPLFLERNDMASYEEFMAATEAILSQGNQQLILCDSGIRTYNNANLPTLDLAS
HHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHH
LIQIKANSHLPIVINPCYAISEDTLPLQTQGIKQLKADGLVLNCSLEEDKAHDALALMAE
HHHEECCCCCCEEEECCEECCCCCCCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHH
VVRELYR
HHHHHHC
>Mature Secondary Structure
MQKPQPLNQTREQITHLDNELLSLLAERRRLSLEVARSKEVDVRPIRDTQREKELLARLV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
TAGREKGLDAHYVISLYQSIIEDSVLNQQAYLHGRANPETQKQQYCIAYLGARGSYSYLA
HHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHEECCCCCCHHHHHEEHHEECCCCCHHHHH
ASRYCQRRQVEMLDLGCQSFDEIVQAVESGHADYGFLPIENTSSGSINEVYDVLQHTSLS
HHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHCCEE
IVGETTIEVSHCLLGKPGSKLSDIKTVYAHPQPISQCSRYLSQHKDLRLEYCSSSAEAME
EEECCHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHCCHHHHHH
KVNQSADNSAAAIGSTEGGALYQLESIESGLANQKINQSRFIVVARKAVAVPEQLPAKTT
HHHCCCCCCCEECCCCCCCCEEEHHHHHHCHHCCCCCCCEEEEEEHHHHCCCCCCCCCEE
LIMATGQKAGALVEALLVLKAHQLNMSKLESRPIPGTPWEEMFYLDIDANISSEAMQQGL
EEEECCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHEEEEEECCCCCHHHHHHHH
KQLERITRFIKVLGCYPCETVKPTQLSNSQLLIEPSTSKAQVISTVSLDPSPYRFSKAYK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEEECCCCCCHHHHHHH
AQASEIHCGPFTIGAGHIGAIAKITLSKSLLQLESSQAALSAFERRVKQLKEAGFQAVIL
CCCCEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEH
DGCHSLVSAEAIIPKLRQTLHQYDLLCVIAIEQATDMPLATGHADMLFLTGKQMFNQALL
HHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCEECCCCCEEEEECHHHHHHHHH
AQAGTLPIPLFLERNDMASYEEFMAATEAILSQGNQQLILCDSGIRTYNNANLPTLDLAS
HHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHH
LIQIKANSHLPIVINPCYAISEDTLPLQTQGIKQLKADGLVLNCSLEEDKAHDALALMAE
HHHEECCCCCCEEEECCEECCCCCCCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHH
VVRELYR
HHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]