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The map label for this gene is aer [H]

Identifier: 117921426

GI number: 117921426

Start: 3591250

End: 3592818

Strand: Direct

Name: aer [H]

Synonym: Shewana3_2987

Alternate gene names: 117921426

Gene position: 3591250-3592818 (Clockwise)

Preceding gene: 117921425

Following gene: 117921427

Centisome position: 72.23

GC content: 51.56

Gene sequence:

>1569_bases
ATGAGCCAGAGTAACCCTAGCCGCAGTAAAACCAGCCAACTCCACAGTAACGCACAGGAAGTCCGCCTCACACCGCAAGA
CGAATTGATTTCAACCACAGATACCCGTGGGATTATTACCTACGTTAATCAACGCTTTGCCGAAGTTTCGGGTTATAAGG
CCGAGGAATTGATCGGCCAGCCTCATAACAAAGTGCGCCACCCTGATATGCCCAGTGCCGCCTTTAAAGAAATGTGGGAA
AAGCTGAAATCCGGCCAATCCTGGCGAGGCATAGTCAAAAACCGCTGTAAGAATGGCGGTTTCTATTGGGTCGATGCCTT
TGTTTCTCCCCTGTTTGAGAATGGGACTATCATAGGTTATCAGTCGGTGCGTATTCAGCCGCAGGCGGCCTATGTCAGTA
AAGCCACGGATATCTACCGCAGGCTAGTACAAAACAAACCCATCCCTAAACCGCTGAGTTTAATGCAAAAACGATTTGTC
TCCGCCGTCGTTGCTACCACAGGGTTACTGATTGCGGGTTACTTTTGGGGTTGGGGAGTGATTTTCGCAGGGGCGATTCT
GATGAGCCTCAATCTGGCGATCTTCTACGATGAGGCCTTTCGCATTCCAGCCAAACTGGTTGAAATGCAAGAAAAATATG
ATTCCATCAGCCGCTATATCTACTCAGGCGCCGATACCTCATCGATTCTCGATTTCCAATTGATCCTATTGCAAGCCAAG
ATGAACGGCGTGCTTGGCCGCACCCAAGATCAGGCCCACCACTTACATGCGATTGCCGATCAGCTGGTGGTGACGACAGA
ACAAACCTATGTCAGCCTAGACCAAGAGAAAAACCAGCTAGAGCAACTCGCCAGTGCAATGGAAGAAATGAGCTCAACCA
TTGCCGAGGTTGCACAAAATACCCAACTGACCTCGACCAGTATCAACACTGCCTACGATCTCTGCCTCAAAAGCAGCGCC
AATATGAAAGCCAACACCCAAAAGGTTGAGCAATTAGCCAAATCCGTGGCCGATGCCGCCAATAATGCCCATCAACTCAA
TAAGGAAGCCGAACGGGTGGCCAGCGCCATGGGCGAGATTGACTCGATTGCCGAGCAGACTAACTTGCTCGCGCTCAACG
CTGCGATTGAGGCGGCTCGCGCAGGCGAGCAAGGCCGCGGGTTTGCGGTTGTCGCCGACGAAGTACGCGCGCTGTCGAGC
CGTACCCAATTGTCGACTAACAGTATTTCCCAGAGCGTCGACAAGATGTTCAGCATGCTAAATGCCTGGGCGAAGGAGAT
GGAGCAGAGCCGTCAGCATGCAGAGCTATGTGCTAACGATATTCAAACTTCTGCTGAGAACGTGAACACCATTTACCAAG
AGGTGAGCGAGATCCACACCTTTGCCCAGCAAAACGCGGTGGCCGCAGATCAGCAGCGCCAAGTGGTGCATGAAATCACT
AACAACATTCACTCCATCACCCAAACCAGCAGCGAAAACCTCGCCGCCACCCATCAAATTGGTGATGCCGCGAATCATTT
AAAACACAATGCCGAAAAGGCCCTAGGTCTACGCCGCGCCTTTGGCTAG

Upstream 100 bases:

>100_bases
ACCATTATCACATAATAAGCCGACTCCAATGAGAGCTGGCACCCGTTTTACCAGTTACATTTACCCAAAAAGTCGTATCG
GCCCTGAATGGACACACTAA

Downstream 100 bases:

>100_bases
TACTCCCGTCGCGCCATTATCAACTAAGATGATGGCGCGATACTCTCCCTCTATGTTTTCCCCTCTACAGTTTCAACCAC
ATCTAAAACCGCTTACAGAT

Product: methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 522; Mature: 521

Protein sequence:

>522_residues
MSQSNPSRSKTSQLHSNAQEVRLTPQDELISTTDTRGIITYVNQRFAEVSGYKAEELIGQPHNKVRHPDMPSAAFKEMWE
KLKSGQSWRGIVKNRCKNGGFYWVDAFVSPLFENGTIIGYQSVRIQPQAAYVSKATDIYRRLVQNKPIPKPLSLMQKRFV
SAVVATTGLLIAGYFWGWGVIFAGAILMSLNLAIFYDEAFRIPAKLVEMQEKYDSISRYIYSGADTSSILDFQLILLQAK
MNGVLGRTQDQAHHLHAIADQLVVTTEQTYVSLDQEKNQLEQLASAMEEMSSTIAEVAQNTQLTSTSINTAYDLCLKSSA
NMKANTQKVEQLAKSVADAANNAHQLNKEAERVASAMGEIDSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALSS
RTQLSTNSISQSVDKMFSMLNAWAKEMEQSRQHAELCANDIQTSAENVNTIYQEVSEIHTFAQQNAVAADQQRQVVHEIT
NNIHSITQTSSENLAATHQIGDAANHLKHNAEKALGLRRAFG

Sequences:

>Translated_522_residues
MSQSNPSRSKTSQLHSNAQEVRLTPQDELISTTDTRGIITYVNQRFAEVSGYKAEELIGQPHNKVRHPDMPSAAFKEMWE
KLKSGQSWRGIVKNRCKNGGFYWVDAFVSPLFENGTIIGYQSVRIQPQAAYVSKATDIYRRLVQNKPIPKPLSLMQKRFV
SAVVATTGLLIAGYFWGWGVIFAGAILMSLNLAIFYDEAFRIPAKLVEMQEKYDSISRYIYSGADTSSILDFQLILLQAK
MNGVLGRTQDQAHHLHAIADQLVVTTEQTYVSLDQEKNQLEQLASAMEEMSSTIAEVAQNTQLTSTSINTAYDLCLKSSA
NMKANTQKVEQLAKSVADAANNAHQLNKEAERVASAMGEIDSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALSS
RTQLSTNSISQSVDKMFSMLNAWAKEMEQSRQHAELCANDIQTSAENVNTIYQEVSEIHTFAQQNAVAADQQRQVVHEIT
NNIHSITQTSSENLAATHQIGDAANHLKHNAEKALGLRRAFG
>Mature_521_residues
SQSNPSRSKTSQLHSNAQEVRLTPQDELISTTDTRGIITYVNQRFAEVSGYKAEELIGQPHNKVRHPDMPSAAFKEMWEK
LKSGQSWRGIVKNRCKNGGFYWVDAFVSPLFENGTIIGYQSVRIQPQAAYVSKATDIYRRLVQNKPIPKPLSLMQKRFVS
AVVATTGLLIAGYFWGWGVIFAGAILMSLNLAIFYDEAFRIPAKLVEMQEKYDSISRYIYSGADTSSILDFQLILLQAKM
NGVLGRTQDQAHHLHAIADQLVVTTEQTYVSLDQEKNQLEQLASAMEEMSSTIAEVAQNTQLTSTSINTAYDLCLKSSAN
MKANTQKVEQLAKSVADAANNAHQLNKEAERVASAMGEIDSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALSSR
TQLSTNSISQSVDKMFSMLNAWAKEMEQSRQHAELCANDIQTSAENVNTIYQEVSEIHTFAQQNAVAADQQRQVVHEITN
NIHSITQTSSENLAATHQIGDAANHLKHNAEKALGLRRAFG

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=494, Percent_Identity=30.9716599190283, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI2367378, Length=318, Percent_Identity=26.4150943396226, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1787690, Length=234, Percent_Identity=28.2051282051282, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788195, Length=255, Percent_Identity=28.6274509803922, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788194, Length=278, Percent_Identity=26.6187050359712, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 57703; Mature: 57571

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSNPSRSKTSQLHSNAQEVRLTPQDELISTTDTRGIITYVNQRFAEVSGYKAEELIGQ
CCCCCCCHHHHHHHHCCHHHEECCCHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHCC
PHNKVRHPDMPSAAFKEMWEKLKSGQSWRGIVKNRCKNGGFYWVDAFVSPLFENGTIIGY
CHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEHHHHHHHHHCCCCEEEE
QSVRIQPQAAYVSKATDIYRRLVQNKPIPKPLSLMQKRFVSAVVATTGLLIAGYFWGWGV
ECEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFAGAILMSLNLAIFYDEAFRIPAKLVEMQEKYDSISRYIYSGADTSSILDFQLILLQAK
HHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
MNGVLGRTQDQAHHLHAIADQLVVTTEQTYVSLDQEKNQLEQLASAMEEMSSTIAEVAQN
HHHCCCCCHHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TQLTSTSINTAYDLCLKSSANMKANTQKVEQLAKSVADAANNAHQLNKEAERVASAMGEI
CCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALSSRTQLSTNSISQSVDKMFSML
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NAWAKEMEQSRQHAELCANDIQTSAENVNTIYQEVSEIHTFAQQNAVAADQQRQVVHEIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
NNIHSITQTSSENLAATHQIGDAANHLKHNAEKALGLRRAFG
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQSNPSRSKTSQLHSNAQEVRLTPQDELISTTDTRGIITYVNQRFAEVSGYKAEELIGQ
CCCCCCHHHHHHHHCCHHHEECCCHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHCC
PHNKVRHPDMPSAAFKEMWEKLKSGQSWRGIVKNRCKNGGFYWVDAFVSPLFENGTIIGY
CHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEHHHHHHHHHCCCCEEEE
QSVRIQPQAAYVSKATDIYRRLVQNKPIPKPLSLMQKRFVSAVVATTGLLIAGYFWGWGV
ECEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFAGAILMSLNLAIFYDEAFRIPAKLVEMQEKYDSISRYIYSGADTSSILDFQLILLQAK
HHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
MNGVLGRTQDQAHHLHAIADQLVVTTEQTYVSLDQEKNQLEQLASAMEEMSSTIAEVAQN
HHHCCCCCHHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TQLTSTSINTAYDLCLKSSANMKANTQKVEQLAKSVADAANNAHQLNKEAERVASAMGEI
CCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALSSRTQLSTNSISQSVDKMFSML
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NAWAKEMEQSRQHAELCANDIQTSAENVNTIYQEVSEIHTFAQQNAVAADQQRQVVHEIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
NNIHSITQTSSENLAATHQIGDAANHLKHNAEKALGLRRAFG
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]