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The map label for this gene is ppnK [H]

Identifier: 117921344

GI number: 117921344

Start: 3472655

End: 3473584

Strand: Direct

Name: ppnK [H]

Synonym: Shewana3_2903

Alternate gene names: 117921344

Gene position: 3472655-3473584 (Clockwise)

Preceding gene: 117921342

Following gene: 117921345

Centisome position: 69.84

GC content: 51.29

Gene sequence:

>930_bases
ATGGGGATCAATTTTGACGTTTCAAGGCCTAAGGCCAGATCTAGCATAAATATGACCACAAAGTTCCACACCATTGGCCT
GATTGGCAAGCCGCACCACCCAGGGACAAATCAAACCCTCAAACGTCTGCACCACTGGCTGACGGTGCAAGGGTATGAAG
TCCTCGTGGAAGAGCGCGTTGCCAGCGAGTTAGGGACCAATATCATCGCGGTCGATTTATTAGAGATTGGCGCACGCTGC
GATTTAGCGATAGTCGTGGGTGGCGATGGCAATATGCTCGGCGCCGCCAGAGTGCTGGCCCGCTTCGATGTGGGCGTGAT
TGGTGTAAACCGTGGCAATCTAGGTTTTTTAACGGATTTACCGCCCGATGCCTTTGAAGAAGCGCTCGCCAAAGTGCTCG
ATGGGGAATTTGATACCGAGCACCGCTTTTTACTCGAAGCCGAGGTCTATCGTCACGGCATGTTAAAAGCGAGCAATACC
GCAGTGAATGAGGCAGTGCTGCATCCTGGTAAAATCGCCCATATGATTGAATTTGAAGTCTATATAGACAATCAATTCAT
GTACAGTCAACGTGCCGACGGCATGATAGTCTCAACCCCGACGGGGTCTACCGCCTATGCCCTGTCGGCAGGTGGCGCCA
TTCTGACCCCCAATTTACAGGCATTAATCTTAGTGCCTATGTTTCCACATACACTGTCGTGTCGCCCCATAGTGGTCGAT
GCCTGCAGCACCATTAAGATGGTCGTCTCCCCTGAAAATGGCGAAAATCTCGAAGTAAGTTGTGATGGCCACGTGCATTT
AGCCGTCTTACCCGGCGATGAAATCATAGTGCGCCGCAGCTCCGAGCAGCTCAGACTTATCCACCCTAAAGGCCATAATT
ACTTCCATGTGTTACGCAGTAAGCTCGGCTGGGGCAGTAAGCTGTTTTAA

Upstream 100 bases:

>100_bases
CTACACCCTCTTGGATCAGATCCTGTTCTGCTTTAATCGACTCGTTGCTCATTTTCACTCCAGCTAAAAATGCTTTGTTT
CTAAATACTCTGGGCATATT

Downstream 100 bases:

>100_bases
GCCCACATTAGGCGAAGGCATAATGGCCACAAAGGCACGCCATCATTAATCACTCAGGTTAATTCCCATACCAGTTGTTA
ACAGAATGGTGTGTTGCGGC

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MGINFDVSRPKARSSINMTTKFHTIGLIGKPHHPGTNQTLKRLHHWLTVQGYEVLVEERVASELGTNIIAVDLLEIGARC
DLAIVVGGDGNMLGAARVLARFDVGVIGVNRGNLGFLTDLPPDAFEEALAKVLDGEFDTEHRFLLEAEVYRHGMLKASNT
AVNEAVLHPGKIAHMIEFEVYIDNQFMYSQRADGMIVSTPTGSTAYALSAGGAILTPNLQALILVPMFPHTLSCRPIVVD
ACSTIKMVVSPENGENLEVSCDGHVHLAVLPGDEIIVRRSSEQLRLIHPKGHNYFHVLRSKLGWGSKLF

Sequences:

>Translated_309_residues
MGINFDVSRPKARSSINMTTKFHTIGLIGKPHHPGTNQTLKRLHHWLTVQGYEVLVEERVASELGTNIIAVDLLEIGARC
DLAIVVGGDGNMLGAARVLARFDVGVIGVNRGNLGFLTDLPPDAFEEALAKVLDGEFDTEHRFLLEAEVYRHGMLKASNT
AVNEAVLHPGKIAHMIEFEVYIDNQFMYSQRADGMIVSTPTGSTAYALSAGGAILTPNLQALILVPMFPHTLSCRPIVVD
ACSTIKMVVSPENGENLEVSCDGHVHLAVLPGDEIIVRRSSEQLRLIHPKGHNYFHVLRSKLGWGSKLF
>Mature_308_residues
GINFDVSRPKARSSINMTTKFHTIGLIGKPHHPGTNQTLKRLHHWLTVQGYEVLVEERVASELGTNIIAVDLLEIGARCD
LAIVVGGDGNMLGAARVLARFDVGVIGVNRGNLGFLTDLPPDAFEEALAKVLDGEFDTEHRFLLEAEVYRHGMLKASNTA
VNEAVLHPGKIAHMIEFEVYIDNQFMYSQRADGMIVSTPTGSTAYALSAGGAILTPNLQALILVPMFPHTLSCRPIVVDA
CSTIKMVVSPENGENLEVSCDGHVHLAVLPGDEIIVRRSSEQLRLIHPKGHNYFHVLRSKLGWGSKLF

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=263, Percent_Identity=31.1787072243346, Blast_Score=99, Evalue=5e-21,
Organism=Escherichia coli, GI1788968, Length=293, Percent_Identity=56.6552901023891, Blast_Score=347, Evalue=7e-97,
Organism=Saccharomyces cerevisiae, GI6320794, Length=242, Percent_Identity=28.9256198347107, Blast_Score=122, Evalue=9e-29,
Organism=Saccharomyces cerevisiae, GI6322509, Length=240, Percent_Identity=30.4166666666667, Blast_Score=120, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6325068, Length=214, Percent_Identity=31.7757009345794, Blast_Score=110, Evalue=3e-25,
Organism=Drosophila melanogaster, GI28573828, Length=253, Percent_Identity=32.4110671936759, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28573830, Length=253, Percent_Identity=32.4110671936759, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28573826, Length=253, Percent_Identity=32.4110671936759, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28573832, Length=253, Percent_Identity=32.4110671936759, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI161077047, Length=253, Percent_Identity=32.4110671936759, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI20129957, Length=276, Percent_Identity=27.1739130434783, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24653422, Length=278, Percent_Identity=26.978417266187, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI281363323, Length=278, Percent_Identity=26.978417266187, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24653424, Length=278, Percent_Identity=26.978417266187, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI281363321, Length=278, Percent_Identity=26.978417266187, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 33773; Mature: 33642

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGINFDVSRPKARSSINMTTKFHTIGLIGKPHHPGTNQTLKRLHHWLTVQGYEVLVEERV
CCCCCCCCCCCCCCCEEEEEEEEEEEEEECCCCCCCHHHHHHHHHHEEECCHHHHHHHHH
ASELGTNIIAVDLLEIGARCDLAIVVGGDGNMLGAARVLARFDVGVIGVNRGNLGFLTDL
HHHHCCCEEEEEHHHCCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCEEEEECC
PPDAFEEALAKVLDGEFDTEHRFLLEAEVYRHGMLKASNTAVNEAVLHPGKIAHMIEFEV
CHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHCCCEECCCCHHHHHHCCCCCEEEEEEEEE
YIDNQFMYSQRADGMIVSTPTGSTAYALSAGGAILTPNLQALILVPMFPHTLSCRPIVVD
EECCEEEECCCCCCEEEECCCCCEEEEEECCCEEECCCCEEEEEEECCCCCCCCCEEEEE
ACSTIKMVVSPENGENLEVSCDGHVHLAVLPGDEIIVRRSSEQLRLIHPKGHNYFHVLRS
CCCEEEEEECCCCCCEEEEEECCEEEEEEECCCEEEEEECCCCEEEECCCCCCHHHHHHH
KLGWGSKLF
HCCCCCCCC
>Mature Secondary Structure 
GINFDVSRPKARSSINMTTKFHTIGLIGKPHHPGTNQTLKRLHHWLTVQGYEVLVEERV
CCCCCCCCCCCCCCEEEEEEEEEEEEEECCCCCCCHHHHHHHHHHEEECCHHHHHHHHH
ASELGTNIIAVDLLEIGARCDLAIVVGGDGNMLGAARVLARFDVGVIGVNRGNLGFLTDL
HHHHCCCEEEEEHHHCCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCEEEEECC
PPDAFEEALAKVLDGEFDTEHRFLLEAEVYRHGMLKASNTAVNEAVLHPGKIAHMIEFEV
CHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHCCCEECCCCHHHHHHCCCCCEEEEEEEEE
YIDNQFMYSQRADGMIVSTPTGSTAYALSAGGAILTPNLQALILVPMFPHTLSCRPIVVD
EECCEEEECCCCCCEEEECCCCCEEEEEECCCEEECCCCEEEEEEECCCCCCCCCEEEEE
ACSTIKMVVSPENGENLEVSCDGHVHLAVLPGDEIIVRRSSEQLRLIHPKGHNYFHVLRS
CCCEEEEEECCCCCCEEEEEECCEEEEEEECCCEEEEEECCCCEEEECCCCCCHHHHHHH
KLGWGSKLF
HCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA