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The map label for this gene is phoR [H]

Identifier: 117921319

GI number: 117921319

Start: 3442246

End: 3443544

Strand: Reverse

Name: phoR [H]

Synonym: Shewana3_2878

Alternate gene names: 117921319

Gene position: 3443544-3442246 (Counterclockwise)

Preceding gene: 117921320

Following gene: 117921318

Centisome position: 69.26

GC content: 49.58

Gene sequence:

>1299_bases
ATGTTTGACTCTTATTCAGGGTACCGGCTGTTTTCGCGCTTAGCGGTGTTTTTACTGCTTTGTTTGCTGATTGGTTTATT
GGTAGGGAAACCCCTCTGGATACTTATCATTGGATTGCTAGGACTGGTGTTCTGGCATTACCGTCAGTTAGCGCGTCTCA
ATTTCTGGTTATGGCGAGATAGAAAATTAACACCTCCCCAGGGCAGTGGCAGTTGGGAAGGGGTGTTTAACGGCATATAC
CGTCTACAGGGCAAAAATCGTCGTCGAGTGGGTCAACTAGCCGCCTTGCTAGGACGTTTTCGCCAAGGGGCCGAGGCCTT
GCCCGATGCGGCAGTCGTGCTCGACTCTGAGCACAATATCTTATGGTGTAACAAGTTAGCTCAGCTGATATTAGGCTTTG
TCTGGCCACAGGATAATGGTCAACGCATCGATAACTTGATCCGCCATCCTGATTTTTCGGCCTATATCAAAGCCGGAAAA
TATAAAGATCCCTTAGAGCTGGCCTCGCCCGTGTCCGATAGACGGCTGCTGGAAATCCGTATCATGGCCTATGGCGATCG
GCAGTTATTGCTCATTGCCCGCGATATTACACGGATAAGACAACTCGAAGGTATGCGTAAAGAATTTGTCGCCAATGTGT
CACACGAACTGAAAACCCCGCTCACTGTATTGCAGGGTTATTTAGAGATGATGCAAAGCATGGCGGAACCCGGTTCGATG
AACGCTAAGCCCTTAGCCTTAATGCAGCAGCAGACACGGCGAATGCAGTCGATGGTGGAGCAATTATTGGTGTTATCACG
CATCGAAGATGCGGCGGATATTAACCTTGAGAACACCGTAAACATGGCGCAGCTGATGGAAGTCTTAAAGGAAGAGGCTA
AGGCGCTGGCGCAGGACAAGTACGAGCTAAGCTTCCACTGTGAAGCGGGACTTAACTCCCATGGCAATGAGTTACAGCTT
AGAAGTGCTTGTTCTAATTTGATTTCGAATGCGATTCGCTACACAGAGCCCGGCGGCAAAATTACCGTGCAATGGCGCAG
TGTGGCAACCGGTGGCCTCTTTAGTGTGACGGATACCGGTGAGGGGATCGCGCCGCAGCATATTAGCCGCTTAACCGAGC
GTTTTTATCGCGTCGACAGTGCGCGCTCAAGGCAAACCGGTGGTAGTGGCCTTGGCTTAGCCATTGTGAAACACGCTTTG
AGTCATCACCACAGTGAGCTCAATATCAGCAGCGAATTGGGTAAAGGCAGTACCTTTAGTTTTGTGATCCCATCCCATTT
GATTGAACGCAAAAAATAA

Upstream 100 bases:

>100_bases
GTTTCTCTACACGCATTTAGTGCCAAATAAGAGATAGGCACAGGTTAGCTTTTAAGCTATCTTGTGCTCCTCCTATTTAG
CCTGATGTCTGGGTTTATTT

Downstream 100 bases:

>100_bases
TTGTCATAGAAACGCATATTATTTTTACATATAAAACAGGCCATTATGGTCTGTTTTGTTTTTTAAACCTCAAGAGTGCG
AGGTTTTTTTCAAAAAAATG

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MFDSYSGYRLFSRLAVFLLLCLLIGLLVGKPLWILIIGLLGLVFWHYRQLARLNFWLWRDRKLTPPQGSGSWEGVFNGIY
RLQGKNRRRVGQLAALLGRFRQGAEALPDAAVVLDSEHNILWCNKLAQLILGFVWPQDNGQRIDNLIRHPDFSAYIKAGK
YKDPLELASPVSDRRLLEIRIMAYGDRQLLLIARDITRIRQLEGMRKEFVANVSHELKTPLTVLQGYLEMMQSMAEPGSM
NAKPLALMQQQTRRMQSMVEQLLVLSRIEDAADINLENTVNMAQLMEVLKEEAKALAQDKYELSFHCEAGLNSHGNELQL
RSACSNLISNAIRYTEPGGKITVQWRSVATGGLFSVTDTGEGIAPQHISRLTERFYRVDSARSRQTGGSGLGLAIVKHAL
SHHHSELNISSELGKGSTFSFVIPSHLIERKK

Sequences:

>Translated_432_residues
MFDSYSGYRLFSRLAVFLLLCLLIGLLVGKPLWILIIGLLGLVFWHYRQLARLNFWLWRDRKLTPPQGSGSWEGVFNGIY
RLQGKNRRRVGQLAALLGRFRQGAEALPDAAVVLDSEHNILWCNKLAQLILGFVWPQDNGQRIDNLIRHPDFSAYIKAGK
YKDPLELASPVSDRRLLEIRIMAYGDRQLLLIARDITRIRQLEGMRKEFVANVSHELKTPLTVLQGYLEMMQSMAEPGSM
NAKPLALMQQQTRRMQSMVEQLLVLSRIEDAADINLENTVNMAQLMEVLKEEAKALAQDKYELSFHCEAGLNSHGNELQL
RSACSNLISNAIRYTEPGGKITVQWRSVATGGLFSVTDTGEGIAPQHISRLTERFYRVDSARSRQTGGSGLGLAIVKHAL
SHHHSELNISSELGKGSTFSFVIPSHLIERKK
>Mature_432_residues
MFDSYSGYRLFSRLAVFLLLCLLIGLLVGKPLWILIIGLLGLVFWHYRQLARLNFWLWRDRKLTPPQGSGSWEGVFNGIY
RLQGKNRRRVGQLAALLGRFRQGAEALPDAAVVLDSEHNILWCNKLAQLILGFVWPQDNGQRIDNLIRHPDFSAYIKAGK
YKDPLELASPVSDRRLLEIRIMAYGDRQLLLIARDITRIRQLEGMRKEFVANVSHELKTPLTVLQGYLEMMQSMAEPGSM
NAKPLALMQQQTRRMQSMVEQLLVLSRIEDAADINLENTVNMAQLMEVLKEEAKALAQDKYELSFHCEAGLNSHGNELQL
RSACSNLISNAIRYTEPGGKITVQWRSVATGGLFSVTDTGEGIAPQHISRLTERFYRVDSARSRQTGGSGLGLAIVKHAL
SHHHSELNISSELGKGSTFSFVIPSHLIERKK

Specific function: Member of the two-component regulatory system phoR/phoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates phoB in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=410, Percent_Identity=52.6829268292683, Blast_Score=444, Evalue=1e-126,
Organism=Escherichia coli, GI1786783, Length=234, Percent_Identity=33.7606837606838, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788393, Length=250, Percent_Identity=26.8, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1790346, Length=210, Percent_Identity=32.8571428571429, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI145693157, Length=221, Percent_Identity=29.4117647058824, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1789149, Length=253, Percent_Identity=29.6442687747036, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1790861, Length=323, Percent_Identity=27.2445820433437, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87082128, Length=233, Percent_Identity=27.4678111587983, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1787894, Length=234, Percent_Identity=29.4871794871795, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI48994928, Length=276, Percent_Identity=27.1739130434783, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788713, Length=227, Percent_Identity=24.2290748898678, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789403, Length=203, Percent_Identity=30.0492610837438, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788549, Length=345, Percent_Identity=23.768115942029, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1789808, Length=218, Percent_Identity=30.7339449541284, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790436, Length=250, Percent_Identity=26, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1790551, Length=217, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788279, Length=217, Percent_Identity=25.3456221198157, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786912, Length=232, Percent_Identity=24.5689655172414, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR021766
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014310 [H]

Pfam domain/function: PF11808 DUF3329; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48745; Mature: 48745

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: PS50109 HIS_KIN ; PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDSYSGYRLFSRLAVFLLLCLLIGLLVGKPLWILIIGLLGLVFWHYRQLARLNFWLWRD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
RKLTPPQGSGSWEGVFNGIYRLQGKNRRRVGQLAALLGRFRQGAEALPDAAVVLDSEHNI
CCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCE
LWCNKLAQLILGFVWPQDNGQRIDNLIRHPDFSAYIKAGKYKDPLELASPVSDRRLLEIR
EHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHCCCCCCCCHHHHCCCCCCEEEEEE
IMAYGDRQLLLIARDITRIRQLEGMRKEFVANVSHELKTPLTVLQGYLEMMQSMAEPGSM
EEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCC
NAKPLALMQQQTRRMQSMVEQLLVLSRIEDAADINLENTVNMAQLMEVLKEEAKALAQDK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHCCC
YELSFHCEAGLNSHGNELQLRSACSNLISNAIRYTEPGGKITVQWRSVATGGLFSVTDTG
CEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCEEECCCC
EGIAPQHISRLTERFYRVDSARSRQTGGSGLGLAIVKHALSHHHSELNISSELGKGSTFS
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCCCEEE
FVIPSHLIERKK
EECCHHHHCCCC
>Mature Secondary Structure
MFDSYSGYRLFSRLAVFLLLCLLIGLLVGKPLWILIIGLLGLVFWHYRQLARLNFWLWRD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
RKLTPPQGSGSWEGVFNGIYRLQGKNRRRVGQLAALLGRFRQGAEALPDAAVVLDSEHNI
CCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCE
LWCNKLAQLILGFVWPQDNGQRIDNLIRHPDFSAYIKAGKYKDPLELASPVSDRRLLEIR
EHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHCCCCCCCCHHHHCCCCCCEEEEEE
IMAYGDRQLLLIARDITRIRQLEGMRKEFVANVSHELKTPLTVLQGYLEMMQSMAEPGSM
EEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCC
NAKPLALMQQQTRRMQSMVEQLLVLSRIEDAADINLENTVNMAQLMEVLKEEAKALAQDK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHCCC
YELSFHCEAGLNSHGNELQLRSACSNLISNAIRYTEPGGKITVQWRSVATGGLFSVTDTG
CEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCEEECCCC
EGIAPQHISRLTERFYRVDSARSRQTGGSGLGLAIVKHALSHHHSELNISSELGKGSTFS
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCCCEEE
FVIPSHLIERKK
EECCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3550103; 9278503; 2187152; 8391104 [H]