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The map label for this gene is map [H]

Identifier: 117921257

GI number: 117921257

Start: 3362783

End: 3363619

Strand: Direct

Name: map [H]

Synonym: Shewana3_2816

Alternate gene names: 117921257

Gene position: 3362783-3363619 (Clockwise)

Preceding gene: 117921239

Following gene: 117921258

Centisome position: 67.63

GC content: 47.67

Gene sequence:

>837_bases
ATGGCGCCAATAGACATCGAAGACACAAGAGAAAACGCAATGAGTATAGTCATTAAGACAGCAGAAGAAATCGAGAAAAT
GCGCGCAGCAGGTAAGCTGGCCGCACAAGTATTAGAAATGATCGCCCCCTATGTTAAGGCCGGCGTGAGCACTAATGAAC
TCAACGATATCTGCGCCAAATATACCGAAGAGCAAGGCGCGATTTCTGCCCCGCTCAACTACCATGGTTTTCCTAAGTCG
ATTTGTACTTCGCTAAACAACGTGATTTGCCATGGTATTCCGAGCGACCGCGTTCTCGAGGATGGCGATATTCTCAATAT
CGATATCACAGTCATCAAAGACGGTTACCACGGTGATACCTCTAAAATGTTCTTAATCGGTGAAGTCAGCCCTAAGGACA
AGCGCCTGTGCCGTATCGCGCAGGAGAGTTTATACCTCGCCATTCGTAAGGTTCGCCCGGGGTTAAAACTGGGTGAAATC
GGCAATACTATCGAAAAATTCATCAAAGCCAGCAAAACAGGCCTTGAGAAATATTCCATCGTGCAAGATTATTGTGGTCA
CGGTATTGGTGCCGGTTTCCATGAAGAGCCGCAAGTCATGCACTACCGTAATGGCGATAACACCATTTTACGCCCTGGCA
TGTGTTTTACCATTGAGCCGATGATCAACGCCGGTCGCCACACCACAGTGTTAGACCGTGACGATAAGTGGACTGTCACC
ACCTCCGATGGTAAAAACTCAGCCCAATGGGAACACACATTATTAGTGACCGAAACCGGTGTAGAAGTCCTGACTCTGCG
TGATGAGGAAGACTTCCCGCGTATCATTAATCACTAA

Upstream 100 bases:

>100_bases
GATAAGCAAAAGCTAACCTTAAACAACCTGCAAGACTTAAACATAACGGCGCGCTTTATACCATAAATAGCCCTAAAGCA
CAAATTTTTGCATCGGGTGG

Downstream 100 bases:

>100_bases
GCGACATACTTAGTACGTTAGGATTCAGAGGATTACTGAACACCTAACTCATCCAAACAAGGGACTCGATGAATACAGCT
CTGCTAGCTAAACAATCATT

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MAPIDIEDTRENAMSIVIKTAEEIEKMRAAGKLAAQVLEMIAPYVKAGVSTNELNDICAKYTEEQGAISAPLNYHGFPKS
ICTSLNNVICHGIPSDRVLEDGDILNIDITVIKDGYHGDTSKMFLIGEVSPKDKRLCRIAQESLYLAIRKVRPGLKLGEI
GNTIEKFIKASKTGLEKYSIVQDYCGHGIGAGFHEEPQVMHYRNGDNTILRPGMCFTIEPMINAGRHTTVLDRDDKWTVT
TSDGKNSAQWEHTLLVTETGVEVLTLRDEEDFPRIINH

Sequences:

>Translated_278_residues
MAPIDIEDTRENAMSIVIKTAEEIEKMRAAGKLAAQVLEMIAPYVKAGVSTNELNDICAKYTEEQGAISAPLNYHGFPKS
ICTSLNNVICHGIPSDRVLEDGDILNIDITVIKDGYHGDTSKMFLIGEVSPKDKRLCRIAQESLYLAIRKVRPGLKLGEI
GNTIEKFIKASKTGLEKYSIVQDYCGHGIGAGFHEEPQVMHYRNGDNTILRPGMCFTIEPMINAGRHTTVLDRDDKWTVT
TSDGKNSAQWEHTLLVTETGVEVLTLRDEEDFPRIINH
>Mature_277_residues
APIDIEDTRENAMSIVIKTAEEIEKMRAAGKLAAQVLEMIAPYVKAGVSTNELNDICAKYTEEQGAISAPLNYHGFPKSI
CTSLNNVICHGIPSDRVLEDGDILNIDITVIKDGYHGDTSKMFLIGEVSPKDKRLCRIAQESLYLAIRKVRPGLKLGEIG
NTIEKFIKASKTGLEKYSIVQDYCGHGIGAGFHEEPQVMHYRNGDNTILRPGMCFTIEPMINAGRHTTVLDRDDKWTVTT
SDGKNSAQWEHTLLVTETGVEVLTLRDEEDFPRIINH

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=273, Percent_Identity=42.4908424908425, Blast_Score=220, Evalue=1e-57,
Organism=Homo sapiens, GI40385867, Length=252, Percent_Identity=41.2698412698413, Blast_Score=199, Evalue=2e-51,
Organism=Escherichia coli, GI1786364, Length=268, Percent_Identity=60.0746268656716, Blast_Score=331, Evalue=3e-92,
Organism=Escherichia coli, GI1788728, Length=256, Percent_Identity=28.125, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1789275, Length=270, Percent_Identity=24.4444444444444, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI71996291, Length=263, Percent_Identity=44.8669201520913, Blast_Score=213, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6323273, Length=266, Percent_Identity=43.984962406015, Blast_Score=228, Evalue=1e-60,
Organism=Drosophila melanogaster, GI21355531, Length=251, Percent_Identity=47.808764940239, Blast_Score=233, Evalue=8e-62,
Organism=Drosophila melanogaster, GI24583427, Length=253, Percent_Identity=41.897233201581, Blast_Score=206, Evalue=2e-53,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 30888; Mature: 30756

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPIDIEDTRENAMSIVIKTAEEIEKMRAAGKLAAQVLEMIAPYVKAGVSTNELNDICAK
CCCCCCCHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
YTEEQGAISAPLNYHGFPKSICTSLNNVICHGIPSDRVLEDGDILNIDITVIKDGYHGDT
HHHCCCCEECCCCCCCCCHHHHHHHHHHEECCCCCCCEECCCCEEEEEEEEEECCCCCCC
SKMFLIGEVSPKDKRLCRIAQESLYLAIRKVRPGLKLGEIGNTIEKFIKASKTGLEKYSI
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHH
VQDYCGHGIGAGFHEEPQVMHYRNGDNTILRPGMCFTIEPMINAGRHTTVLDRDDKWTVT
HHHHHCCCCCCCCCCCCCEEEEECCCCCEECCCCEEEECHHHCCCCCEEEEECCCCEEEE
TSDGKNSAQWEHTLLVTETGVEVLTLRDEEDFPRIINH
ECCCCCCCCEEEEEEEEECCEEEEEECCCCCCHHHHCC
>Mature Secondary Structure 
APIDIEDTRENAMSIVIKTAEEIEKMRAAGKLAAQVLEMIAPYVKAGVSTNELNDICAK
CCCCCCHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
YTEEQGAISAPLNYHGFPKSICTSLNNVICHGIPSDRVLEDGDILNIDITVIKDGYHGDT
HHHCCCCEECCCCCCCCCHHHHHHHHHHEECCCCCCCEECCCCEEEEEEEEEECCCCCCC
SKMFLIGEVSPKDKRLCRIAQESLYLAIRKVRPGLKLGEIGNTIEKFIKASKTGLEKYSI
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHH
VQDYCGHGIGAGFHEEPQVMHYRNGDNTILRPGMCFTIEPMINAGRHTTVLDRDDKWTVT
HHHHHCCCCCCCCCCCCCEEEEECCCCCEECCCCEEEECHHHCCCCCEEEEECCCCEEEE
TSDGKNSAQWEHTLLVTETGVEVLTLRDEEDFPRIINH
ECCCCCCCCEEEEEEEEECCEEEEEECCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]