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The map label for this gene is betT [H]

Identifier: 117921160

GI number: 117921160

Start: 3249328

End: 3251304

Strand: Reverse

Name: betT [H]

Synonym: Shewana3_2719

Alternate gene names: 117921160

Gene position: 3251304-3249328 (Counterclockwise)

Preceding gene: 117921161

Following gene: 117921159

Centisome position: 65.39

GC content: 50.03

Gene sequence:

>1977_bases
ATGTCTATCAAGTCGAGTATTAATCCACCGGTTTTTTATTCGTCGGTCTTTTTTATCACCTTAATGGTGATGATCTGCGC
CATTTGGCCTACCGAGGCCAATCACTTTTTCAAATCCATGCAGTCTTGGCTAGAAGCGAAAGCAGGCTGGTTATATATCC
TTGGCGTGGCGATTTTTCTGATTTTTATCATCTTTGTCATGGTCAGTCGCTTTGGCGATATTAAGCTTGGCCCCGACCAT
GCTGTGCCCGATTATAGCTATAAGAGCTGGATTGCCATGCTGTTTTCGGCGGGGATGGGGATTGGATTGATGTTCTTCGG
CGTTGCCGAACCTGTGATGCATTACTTAGCGCCGCCCGATGCAACGCCTGAGAGTTTGGCCGCCGCCAAAGAAGCGATGA
AGATTACGTTCTTCCATTGGGGCATACATGCATGGGCGATTTACGGGGTGGTTGCCCTGAGTTTGGCCTATTTTGCCTAT
CGGCATAAGCTGCCACTGTTACCCCGCAGCGCACTCTATCCCTTAATCGGTGAGCGTATTCATGGTCCGATTGGCCACTG
CGTCGATACCTTTGCGGTATTGGGGACAATGTTTGGGGTCGCGACTTCCCTAGGGTTTGGAGTATTGCAGGTTAACTCGG
GCCTAAGCTATTTATTCGAGCAACTGCCGAATAACACCACTGTGCAAGTGTCGCTGATTATTGGCATTACCTTACTCGCC
ACTCTGTCGGTATTTTCGGGGCTCGATAAAGGAGTGAAGCGCTTAAGTGAGCTTAACTTAGGCTTGGCCCTTATCCTGTT
GCTGATTGTGCTAATCCTTGGCCCAACGGTGATGTTGCTGCAGGCCTTTGTGCAAAATACCGGCAGTTATCTCAGTGATA
TCGTTAATAAAACCTTTAATCTGTACGCCTATCAGCATAAGGAAGATTGGCTTGGCGGTTGGACGCTACTCTACTGGGGC
TGGTGGATCTCTTGGTCACCTTTTGTCGGCACCTTTATTGCGCGGGTGAGTCGCGGCCGTACCATACGTGAGTTCTTAGT
CGGCATTTTATTTGTGCCTTCGGCGCTGACCTTTTTATGGATGACGGTATTTGGTAACTCGGCCATCGACGCCATTATGA
ATCAAGGCGCGACCTACCTGAGCGAAGCGGTGAATACCAATGTGCCCGTGGCTCTGTTTGTGTTTTTTGAACATATGCCG
TTCCCGCATCTGTTATCGGGCATTGGGATTTGTTTAGTGGTGACCTTTTTTGTGACCTCATCAGACTCGGGATCCTTAGT
AATCGACAACCTGACCTCGGGGGGCGATAACAATGCGCCTGTCTGGCAACGGGTGTTTTGGGCATTGCTGCAGGGCGTGG
TGGCCTCGGTATTGCTGCTTGCGGGGGGGTTACAGGCGCTCCAAACCGCCGCTATTGCCAGTGCGATGCCATTTTTATGT
GTGATGCTGCTGATGTGTTTAGGGCTGTATAAGGCGCTGAAGGATGATTGGCTGAAAATCAACAGCGTGCAGCTCCATAC
CACCAGTGTGCAATATGCTAAGACCAATATCAGTTGGGAGGAGCGTATCGAAGTCTTAGTGTCGCATCCCACCGAAGATG
AGGCGCGTATCTTCCTCAATAATGTCGCGACACCGGCGTTATCTAAGGTGTGTCAGCAATTTATGAGCAAGGGCCTGACG
GCGGATCTTGAGTATCTCGACGGCAAAGTGCGATTGGTGATCAGTAACGAAGCCTATCAACCCTTCGTATACGGTGTGCG
GATGCGCTGCTTTGAAATCGTTAATCCCGTCGGCGAAGAGTTAGAGCAAGGCAACAATTGGTATTATCGCGCCGAAGTGT
ACTTAGAGCAGGGCGGCCAGCACTATGACGTGATGGGCTATACCGAAGAGCAGTTATTGGCGGATGTGGTCACTCAATAC
GAGAAATACCTGCATTATTTGCACTTGTCCAATGCCGACCAAGGACATGTCGCCTAA

Upstream 100 bases:

>100_bases
CCTGATCACATACTGCTGAGGCTAGAGTTATCTATTATTGAGCTATCTCTTCAAAATCGAAGGGATTTTAATAGGGAACT
GGCTAGAACAAGGGAGTTTT

Downstream 100 bases:

>100_bases
ACGCTTTGCGTGTCAGAAATATTGCCCCAAGGAATAACTCGGATTATCCTTGGGGCACTTTTTTAGGGGTCATCAGTTAG
GTGTGAGCATGTCAGCAAAT

Product: choline/carnitine/betaine transporter

Products: Proton [Cytoplasm]; choline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 658; Mature: 657

Protein sequence:

>658_residues
MSIKSSINPPVFYSSVFFITLMVMICAIWPTEANHFFKSMQSWLEAKAGWLYILGVAIFLIFIIFVMVSRFGDIKLGPDH
AVPDYSYKSWIAMLFSAGMGIGLMFFGVAEPVMHYLAPPDATPESLAAAKEAMKITFFHWGIHAWAIYGVVALSLAYFAY
RHKLPLLPRSALYPLIGERIHGPIGHCVDTFAVLGTMFGVATSLGFGVLQVNSGLSYLFEQLPNNTTVQVSLIIGITLLA
TLSVFSGLDKGVKRLSELNLGLALILLLIVLILGPTVMLLQAFVQNTGSYLSDIVNKTFNLYAYQHKEDWLGGWTLLYWG
WWISWSPFVGTFIARVSRGRTIREFLVGILFVPSALTFLWMTVFGNSAIDAIMNQGATYLSEAVNTNVPVALFVFFEHMP
FPHLLSGIGICLVVTFFVTSSDSGSLVIDNLTSGGDNNAPVWQRVFWALLQGVVASVLLLAGGLQALQTAAIASAMPFLC
VMLLMCLGLYKALKDDWLKINSVQLHTTSVQYAKTNISWEERIEVLVSHPTEDEARIFLNNVATPALSKVCQQFMSKGLT
ADLEYLDGKVRLVISNEAYQPFVYGVRMRCFEIVNPVGEELEQGNNWYYRAEVYLEQGGQHYDVMGYTEEQLLADVVTQY
EKYLHYLHLSNADQGHVA

Sequences:

>Translated_658_residues
MSIKSSINPPVFYSSVFFITLMVMICAIWPTEANHFFKSMQSWLEAKAGWLYILGVAIFLIFIIFVMVSRFGDIKLGPDH
AVPDYSYKSWIAMLFSAGMGIGLMFFGVAEPVMHYLAPPDATPESLAAAKEAMKITFFHWGIHAWAIYGVVALSLAYFAY
RHKLPLLPRSALYPLIGERIHGPIGHCVDTFAVLGTMFGVATSLGFGVLQVNSGLSYLFEQLPNNTTVQVSLIIGITLLA
TLSVFSGLDKGVKRLSELNLGLALILLLIVLILGPTVMLLQAFVQNTGSYLSDIVNKTFNLYAYQHKEDWLGGWTLLYWG
WWISWSPFVGTFIARVSRGRTIREFLVGILFVPSALTFLWMTVFGNSAIDAIMNQGATYLSEAVNTNVPVALFVFFEHMP
FPHLLSGIGICLVVTFFVTSSDSGSLVIDNLTSGGDNNAPVWQRVFWALLQGVVASVLLLAGGLQALQTAAIASAMPFLC
VMLLMCLGLYKALKDDWLKINSVQLHTTSVQYAKTNISWEERIEVLVSHPTEDEARIFLNNVATPALSKVCQQFMSKGLT
ADLEYLDGKVRLVISNEAYQPFVYGVRMRCFEIVNPVGEELEQGNNWYYRAEVYLEQGGQHYDVMGYTEEQLLADVVTQY
EKYLHYLHLSNADQGHVA
>Mature_657_residues
SIKSSINPPVFYSSVFFITLMVMICAIWPTEANHFFKSMQSWLEAKAGWLYILGVAIFLIFIIFVMVSRFGDIKLGPDHA
VPDYSYKSWIAMLFSAGMGIGLMFFGVAEPVMHYLAPPDATPESLAAAKEAMKITFFHWGIHAWAIYGVVALSLAYFAYR
HKLPLLPRSALYPLIGERIHGPIGHCVDTFAVLGTMFGVATSLGFGVLQVNSGLSYLFEQLPNNTTVQVSLIIGITLLAT
LSVFSGLDKGVKRLSELNLGLALILLLIVLILGPTVMLLQAFVQNTGSYLSDIVNKTFNLYAYQHKEDWLGGWTLLYWGW
WISWSPFVGTFIARVSRGRTIREFLVGILFVPSALTFLWMTVFGNSAIDAIMNQGATYLSEAVNTNVPVALFVFFEHMPF
PHLLSGIGICLVVTFFVTSSDSGSLVIDNLTSGGDNNAPVWQRVFWALLQGVVASVLLLAGGLQALQTAAIASAMPFLCV
MLLMCLGLYKALKDDWLKINSVQLHTTSVQYAKTNISWEERIEVLVSHPTEDEARIFLNNVATPALSKVCQQFMSKGLTA
DLEYLDGKVRLVISNEAYQPFVYGVRMRCFEIVNPVGEELEQGNNWYYRAEVYLEQGGQHYDVMGYTEEQLLADVVTQYE
KYLHYLHLSNADQGHVA

Specific function: High-affinity uptake of choline driven by a proton- motive force [H]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family [H]

Homologues:

Organism=Escherichia coli, GI1786506, Length=664, Percent_Identity=38.5542168674699, Blast_Score=508, Evalue=1e-145,
Organism=Escherichia coli, GI1788102, Length=460, Percent_Identity=30.2173913043478, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI1786224, Length=500, Percent_Identity=26.4, Blast_Score=177, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000060
- InterPro:   IPR018093 [H]

Pfam domain/function: PF02028 BCCT [H]

EC number: NA

Molecular weight: Translated: 73204; Mature: 73073

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS01303 BCCT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKSSINPPVFYSSVFFITLMVMICAIWPTEANHFFKSMQSWLEAKAGWLYILGVAIFL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
IFIIFVMVSRFGDIKLGPDHAVPDYSYKSWIAMLFSAGMGIGLMFFGVAEPVMHYLAPPD
HHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
ATPESLAAAKEAMKITFFHWGIHAWAIYGVVALSLAYFAYRHKLPLLPRSALYPLIGERI
CCHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
HGPIGHCVDTFAVLGTMFGVATSLGFGVLQVNSGLSYLFEQLPNNTTVQVSLIIGITLLA
CCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHCCCCCEEEEHHHHHHHHHH
TLSVFSGLDKGVKRLSELNLGLALILLLIVLILGPTVMLLQAFVQNTGSYLSDIVNKTFN
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
LYAYQHKEDWLGGWTLLYWGWWISWSPFVGTFIARVSRGRTIREFLVGILFVPSALTFLW
HEEEECCHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
MTVFGNSAIDAIMNQGATYLSEAVNTNVPVALFVFFEHMPFPHLLSGIGICLVVTFFVTS
HHHHCCHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
SDSGSLVIDNLTSGGDNNAPVWQRVFWALLQGVVASVLLLAGGLQALQTAAIASAMPFLC
CCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
VMLLMCLGLYKALKDDWLKINSVQLHTTSVQYAKTNISWEERIEVLVSHPTEDEARIFLN
HHHHHHHHHHHHHHHCCEEECEEEEEECEEHHHCCCCCHHHHHHHHHCCCCCCHHHHHHH
NVATPALSKVCQQFMSKGLTADLEYLDGKVRLVISNEAYQPFVYGVRMRCFEIVNPVGEE
HCCCHHHHHHHHHHHHCCCCCCHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
LEQGNNWYYRAEVYLEQGGQHYDVMGYTEEQLLADVVTQYEKYLHYLHLSNADQGHVA
HHCCCCEEEEEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SIKSSINPPVFYSSVFFITLMVMICAIWPTEANHFFKSMQSWLEAKAGWLYILGVAIFL
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH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HHCCCCEEEEEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; choline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + choline [Periplasm] = Proton [Cytoplasm] + choline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]