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The map label for this gene is ppiD [H]

Identifier: 117921098

GI number: 117921098

Start: 3170350

End: 3172215

Strand: Reverse

Name: ppiD [H]

Synonym: Shewana3_2657

Alternate gene names: 117921098

Gene position: 3172215-3170350 (Counterclockwise)

Preceding gene: 117921099

Following gene: 117921089

Centisome position: 63.8

GC content: 47.96

Gene sequence:

>1866_bases
ATGTTAGAAAAGATCCGCGACGGTTCGCAAGGCGTGATTGCTAAAGGCATTCTCGTACTTGTGATTTTATCTTTTGCATT
TGCAGGCGTGAGTAGCTATTTAGGCTCAAAATCGGACGTCCCTGCCGCAGAAGTCAACGGTGACAAAATCACTAAAGCCG
AGTTAGAGCAGGCCTATCAGAGCGAACGCGCTCGTATGGAGCAACAACTGGGCGAAATGTTTGCTGCGTTATCTGCCGAC
GAAAGATACCTAGAAAGCATCAAGCAGAGCGTACTCGAACGTTTAGTGGCCGATAAATTGATTGATCAAGCTGCCGCCGC
GATGGGGCTGCGTGTGTCTGACGAGCAAATTATCACGGCGATTAAATCAGAACCCGCTTTCCAAACCGATGGCAAATTCG
ATAACGACCGTTATCAAGCGATTTTGCGCCAGTTAGGCTATCAGCCACAAACCTTCAGAAGCATGATGCGTGTCGATATG
ACCCGTCGTCAGTTAACTGCAGCGTTAGTGGGCACTGAATTCGTATTACCTGGTGAAGCTAAGCAATTAGCTGAGCTGCA
AGGTCAAACTCGCGACATTCGTTACTTAGTTGTGGACTCTGCGCCATTCCTTGCGAATGCCTCTGTGACAGACGAGCAAG
TTAAAAACTACTACGACACCAACCAAGGCCAGTTTATGAGCCCTGAGAAGGTGAGCTTAGAGTATGTTGAGTTAAACGCG
GCGGATTTTGCTAAAGACAGCAAAGTGACGGATGAAGAAGCTCAGGCTTATTACGATGAACACAAGACGCAATATGTGTC
TAACGAGAAACGTTTAGCGGCGCACATTCTGATTGGCCCTGGCAGCGATGAAGCGGCGGCAAAAGCCAAGGCTGAAGATT
TAGCTAAGCAGTTAGATAACGGTGCTGATTTTGCTGAGTTAGCTAAAGCCAATTCTGAAGATACCTTAAGTGCGGAGCAG
GGCGGTAAATTAGACTGGTTTGAACCCGGTGTAATGGACCCAAGCTTTGATACTGCACTGTTTGCACTGCAAAAAGGTCA
GCATTCAGCGGTAGTGAAAACGGATTTTGGTTTCCACATCATCAAACTGTTAGACGTTCAGCCTGGTACTACAGTGCCAT
TTGCGGATGTGAAAGCGAAGATTGTGGCTCAGCTGCAAGAGAAGAAAGCGGTCGATCAATTCTATAGCTTACAAAGCAAA
CTGGCTGATACCAGCTACGAAGTGCCAGATACCTTAGCCGAAACCGCAAAAGTGGTGGGTGTTGAGATTAAGGCTACGCC
AATGTTCTCACGTGATGATGTGCCAACGGCATTGAACAAGCCTGATGTGGTTAAAGCGGCATTCTCTGACACTGTGTTAC
GCCAAGGTCTAAACAGTGAAGTCATTGAACTTGAGCCAAACCATGTTGTGGTTATCCGTATGAAGGAACATCACGATGCG
GGCACTATGCCATTAGCCGAAGTGAAGGCCGACATCGCTGAGCGTTTGAAGCAAGATCAAGCGAACGAAGCGGCACGTGC
TAAAGCGCAGGAGCTGATGACCCAAGTTAAAGCGGGCGCGACTGATGTGAGTTTAACGGCTAAGACTAAACTGGGTCGTG
GCGCACAAGACGTAGACGCAGCCATTGTAGGCAAAGCCTTCCAAATGCCAACCCCGACTGCTACACCTGTGGTTGACACT
GTTGGTTTAGCCAATGGCTACGCTGTGATTGCACTGGATAAAGTAAATGCGGCTGAGTCTGTTAGCGATGAGTTAGTTAA
TGCGCTGAAACAACGCTTAAATGCACAATACAGCGAAGCGGATTACCGCGGTCTGATTGAGTCACTGAAAGCGAATGCGA
AAGTTCATTACCCTGTAGAAGGTTAA

Upstream 100 bases:

>100_bases
ACCAGTGGTAGCGTCTGAATAATCCCCATAAATTACAGAAAGGCGCATCTCAAGTTGATGCGCCTTTTTATTTTGTTAAT
CGCAACGAGCGAGAAATCTG

Downstream 100 bases:

>100_bases
TGATGATAAGGGATAGCTGAGCTTATCCCTTATATTGGCGAAGCAATAAAAGCTTTCGCGAAGCAAATAGAAAAGGCCAA
GTGTTTACTTGGCCTTTTTG

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 621; Mature: 621

Protein sequence:

>621_residues
MLEKIRDGSQGVIAKGILVLVILSFAFAGVSSYLGSKSDVPAAEVNGDKITKAELEQAYQSERARMEQQLGEMFAALSAD
ERYLESIKQSVLERLVADKLIDQAAAAMGLRVSDEQIITAIKSEPAFQTDGKFDNDRYQAILRQLGYQPQTFRSMMRVDM
TRRQLTAALVGTEFVLPGEAKQLAELQGQTRDIRYLVVDSAPFLANASVTDEQVKNYYDTNQGQFMSPEKVSLEYVELNA
ADFAKDSKVTDEEAQAYYDEHKTQYVSNEKRLAAHILIGPGSDEAAAKAKAEDLAKQLDNGADFAELAKANSEDTLSAEQ
GGKLDWFEPGVMDPSFDTALFALQKGQHSAVVKTDFGFHIIKLLDVQPGTTVPFADVKAKIVAQLQEKKAVDQFYSLQSK
LADTSYEVPDTLAETAKVVGVEIKATPMFSRDDVPTALNKPDVVKAAFSDTVLRQGLNSEVIELEPNHVVVIRMKEHHDA
GTMPLAEVKADIAERLKQDQANEAARAKAQELMTQVKAGATDVSLTAKTKLGRGAQDVDAAIVGKAFQMPTPTATPVVDT
VGLANGYAVIALDKVNAAESVSDELVNALKQRLNAQYSEADYRGLIESLKANAKVHYPVEG

Sequences:

>Translated_621_residues
MLEKIRDGSQGVIAKGILVLVILSFAFAGVSSYLGSKSDVPAAEVNGDKITKAELEQAYQSERARMEQQLGEMFAALSAD
ERYLESIKQSVLERLVADKLIDQAAAAMGLRVSDEQIITAIKSEPAFQTDGKFDNDRYQAILRQLGYQPQTFRSMMRVDM
TRRQLTAALVGTEFVLPGEAKQLAELQGQTRDIRYLVVDSAPFLANASVTDEQVKNYYDTNQGQFMSPEKVSLEYVELNA
ADFAKDSKVTDEEAQAYYDEHKTQYVSNEKRLAAHILIGPGSDEAAAKAKAEDLAKQLDNGADFAELAKANSEDTLSAEQ
GGKLDWFEPGVMDPSFDTALFALQKGQHSAVVKTDFGFHIIKLLDVQPGTTVPFADVKAKIVAQLQEKKAVDQFYSLQSK
LADTSYEVPDTLAETAKVVGVEIKATPMFSRDDVPTALNKPDVVKAAFSDTVLRQGLNSEVIELEPNHVVVIRMKEHHDA
GTMPLAEVKADIAERLKQDQANEAARAKAQELMTQVKAGATDVSLTAKTKLGRGAQDVDAAIVGKAFQMPTPTATPVVDT
VGLANGYAVIALDKVNAAESVSDELVNALKQRLNAQYSEADYRGLIESLKANAKVHYPVEG
>Mature_621_residues
MLEKIRDGSQGVIAKGILVLVILSFAFAGVSSYLGSKSDVPAAEVNGDKITKAELEQAYQSERARMEQQLGEMFAALSAD
ERYLESIKQSVLERLVADKLIDQAAAAMGLRVSDEQIITAIKSEPAFQTDGKFDNDRYQAILRQLGYQPQTFRSMMRVDM
TRRQLTAALVGTEFVLPGEAKQLAELQGQTRDIRYLVVDSAPFLANASVTDEQVKNYYDTNQGQFMSPEKVSLEYVELNA
ADFAKDSKVTDEEAQAYYDEHKTQYVSNEKRLAAHILIGPGSDEAAAKAKAEDLAKQLDNGADFAELAKANSEDTLSAEQ
GGKLDWFEPGVMDPSFDTALFALQKGQHSAVVKTDFGFHIIKLLDVQPGTTVPFADVKAKIVAQLQEKKAVDQFYSLQSK
LADTSYEVPDTLAETAKVVGVEIKATPMFSRDDVPTALNKPDVVKAAFSDTVLRQGLNSEVIELEPNHVVVIRMKEHHDA
GTMPLAEVKADIAERLKQDQANEAARAKAQELMTQVKAGATDVSLTAKTKLGRGAQDVDAAIVGKAFQMPTPTATPVVDT
VGLANGYAVIALDKVNAAESVSDELVNALKQRLNAQYSEADYRGLIESLKANAKVHYPVEG

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=630, Percent_Identity=32.5396825396825, Blast_Score=347, Evalue=1e-96,
Organism=Escherichia coli, GI1786238, Length=340, Percent_Identity=28.2352941176471, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 67651; Mature: 67651

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKIRDGSQGVIAKGILVLVILSFAFAGVSSYLGSKSDVPAAEVNGDKITKAELEQAYQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
SERARMEQQLGEMFAALSADERYLESIKQSVLERLVADKLIDQAAAAMGLRVSDEQIITA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
IKSEPAFQTDGKFDNDRYQAILRQLGYQPQTFRSMMRVDMTRRQLTAALVGTEFVLPGEA
HHCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCH
KQLAELQGQTRDIRYLVVDSAPFLANASVTDEQVKNYYDTNQGQFMSPEKVSLEYVELNA
HHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEEEECH
ADFAKDSKVTDEEAQAYYDEHKTQYVSNEKRLAAHILIGPGSDEAAAKAKAEDLAKQLDN
HHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHCC
GADFAELAKANSEDTLSAEQGGKLDWFEPGVMDPSFDTALFALQKGQHSAVVKTDFGFHI
CCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCEEE
IKLLDVQPGTTVPFADVKAKIVAQLQEKKAVDQFYSLQSKLADTSYEVPDTLAETAKVVG
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHE
VEIKATPMFSRDDVPTALNKPDVVKAAFSDTVLRQGLNSEVIELEPNHVVVIRMKEHHDA
EEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEEECCCCC
GTMPLAEVKADIAERLKQDQANEAARAKAQELMTQVKAGATDVSLTAKTKLGRGAQDVDA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCCCCHHHHH
AIVGKAFQMPTPTATPVVDTVGLANGYAVIALDKVNAAESVSDELVNALKQRLNAQYSEA
HHHHHHHCCCCCCCCCHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHH
DYRGLIESLKANAKVHYPVEG
HHHHHHHHHHCCCEEECCCCC
>Mature Secondary Structure
MLEKIRDGSQGVIAKGILVLVILSFAFAGVSSYLGSKSDVPAAEVNGDKITKAELEQAYQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
SERARMEQQLGEMFAALSADERYLESIKQSVLERLVADKLIDQAAAAMGLRVSDEQIITA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
IKSEPAFQTDGKFDNDRYQAILRQLGYQPQTFRSMMRVDMTRRQLTAALVGTEFVLPGEA
HHCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCH
KQLAELQGQTRDIRYLVVDSAPFLANASVTDEQVKNYYDTNQGQFMSPEKVSLEYVELNA
HHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEEEECH
ADFAKDSKVTDEEAQAYYDEHKTQYVSNEKRLAAHILIGPGSDEAAAKAKAEDLAKQLDN
HHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHCC
GADFAELAKANSEDTLSAEQGGKLDWFEPGVMDPSFDTALFALQKGQHSAVVKTDFGFHI
CCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCEEE
IKLLDVQPGTTVPFADVKAKIVAQLQEKKAVDQFYSLQSKLADTSYEVPDTLAETAKVVG
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHE
VEIKATPMFSRDDVPTALNKPDVVKAAFSDTVLRQGLNSEVIELEPNHVVVIRMKEHHDA
EEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEEECCCCC
GTMPLAEVKADIAERLKQDQANEAARAKAQELMTQVKAGATDVSLTAKTKLGRGAQDVDA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCCCCHHHHH
AIVGKAFQMPTPTATPVVDTVGLANGYAVIALDKVNAAESVSDELVNALKQRLNAQYSEA
HHHHHHHCCCCCCCCCHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHH
DYRGLIESLKANAKVHYPVEG
HHHHHHHHHHCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]