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The map label for this gene is namA [H]

Identifier: 117920872

GI number: 117920872

Start: 2912312

End: 2913424

Strand: Reverse

Name: namA [H]

Synonym: Shewana3_2429

Alternate gene names: 117920872

Gene position: 2913424-2912312 (Counterclockwise)

Preceding gene: 117920875

Following gene: 117920869

Centisome position: 58.59

GC content: 52.29

Gene sequence:

>1113_bases
ATGACCCAGCTATTTTCTCCTTTCAGATTAAAAGATATCACGCTTAAAAACCGCATTGCCGTGGCACCTATGTGTCAGTA
TCAGGCTCACGACGGGCTGAGTAACGATTGGCATCAAGTACATTACACTAGTCTCGCTCGCGGCGGCGCAGGTTTAGTGG
TGGTTGAGGCGACGGCCGTATCGCCTGAGGGACGGATCACCCCGCGCTGCTTAGGATTGTGGAACGAGGAACAAGCGGCA
GGTTTGGCCAACATCGCCTCGGCGATTAAAGGTGCTGGCGCGGTGGCGGGGATCCAAATCGCCCATGCTGGTCGTAAAGC
CAGTGCCAACATTCCTTGGGAAGGGGATGACCATATTGAAGGTGACGAAGGATGGCAAACGCTTTCGCCATCGGCCGTGG
CATTTGGTGCTAACCTTGGCAAAGTACCAACAGCCATGACGATTGACGATATTCAACGTGTGAAAGCCGATTTCGTTGCA
GCGGCCAAGCGGGCGCTCGAGGCAGGGTTTGAATGGTTAGAGTTGCACTTTGCCCACGGTTATTTAGCGCAAAGCTTCTT
CTCGACCTATGCCAACCAACGTACCGATGAATACGGTGGTGATGCACAAGGGCGAGGCCGTTTTCTTATCGAGACGGTTG
AGGCGGTGAGGGCGGTTTGGCCTGAACATTTACCGTTAACGGCGCGCTTTGGGGTGATTGAATTTGATGATAAAGACGAG
CAAACCCTGAGTGAGTCCATCGCCTTGGTGAAGCAATTTAAGCGCGCTGGTCTCGATATGCTTAACGTCAGTATTTGTTT
TTCAACACCTACGGCCAATATTCCATGGCGCCCGGCTTTTTTGGCGCCTATTGCCGAGCGAGTGCGTCGTGAAGTGGGTT
TCCCGGTGGCAACGTCATGGGGCATGGATAATCCTCACCACGCAGAGCAAGCGATTCAAGATCAGCAAATGGATTTAGTC
ATGATAGGTAAAGCGTTCTTGGCTAACCCTCACTGGCCGTATCAAGCGGCACAAACCTTAAAGGTTTCGCGTCCATCTTG
GGTGTTACCTTCATCCTACGCCCATTGGTTAGAGCGTTATTCCACCGTGAAGGCGGAATCATCCATAGATTGA

Upstream 100 bases:

>100_bases
AACGAAATCTTATAGAACCTATAATATGGTGATACTTTTAATTATGGCACGTTCGTTTTAGTCTGTCCTCATCTAGTTAA
CCCATGGTTAGGACTGTCAG

Downstream 100 bases:

>100_bases
GCTAGTTCTTAGCCAAATAAAAAGCCCCACGATGAAGTGGGGCTTTTTGTTTATTGTTTATTTTTTTCTCGTTTTAATCC
AAGCTTTACTGGGAGCAATA

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MTQLFSPFRLKDITLKNRIAVAPMCQYQAHDGLSNDWHQVHYTSLARGGAGLVVVEATAVSPEGRITPRCLGLWNEEQAA
GLANIASAIKGAGAVAGIQIAHAGRKASANIPWEGDDHIEGDEGWQTLSPSAVAFGANLGKVPTAMTIDDIQRVKADFVA
AAKRALEAGFEWLELHFAHGYLAQSFFSTYANQRTDEYGGDAQGRGRFLIETVEAVRAVWPEHLPLTARFGVIEFDDKDE
QTLSESIALVKQFKRAGLDMLNVSICFSTPTANIPWRPAFLAPIAERVRREVGFPVATSWGMDNPHHAEQAIQDQQMDLV
MIGKAFLANPHWPYQAAQTLKVSRPSWVLPSSYAHWLERYSTVKAESSID

Sequences:

>Translated_370_residues
MTQLFSPFRLKDITLKNRIAVAPMCQYQAHDGLSNDWHQVHYTSLARGGAGLVVVEATAVSPEGRITPRCLGLWNEEQAA
GLANIASAIKGAGAVAGIQIAHAGRKASANIPWEGDDHIEGDEGWQTLSPSAVAFGANLGKVPTAMTIDDIQRVKADFVA
AAKRALEAGFEWLELHFAHGYLAQSFFSTYANQRTDEYGGDAQGRGRFLIETVEAVRAVWPEHLPLTARFGVIEFDDKDE
QTLSESIALVKQFKRAGLDMLNVSICFSTPTANIPWRPAFLAPIAERVRREVGFPVATSWGMDNPHHAEQAIQDQQMDLV
MIGKAFLANPHWPYQAAQTLKVSRPSWVLPSSYAHWLERYSTVKAESSID
>Mature_369_residues
TQLFSPFRLKDITLKNRIAVAPMCQYQAHDGLSNDWHQVHYTSLARGGAGLVVVEATAVSPEGRITPRCLGLWNEEQAAG
LANIASAIKGAGAVAGIQIAHAGRKASANIPWEGDDHIEGDEGWQTLSPSAVAFGANLGKVPTAMTIDDIQRVKADFVAA
AKRALEAGFEWLELHFAHGYLAQSFFSTYANQRTDEYGGDAQGRGRFLIETVEAVRAVWPEHLPLTARFGVIEFDDKDEQ
TLSESIALVKQFKRAGLDMLNVSICFSTPTANIPWRPAFLAPIAERVRREVGFPVATSWGMDNPHHAEQAIQDQQMDLVM
IGKAFLANPHWPYQAAQTLKVSRPSWVLPSSYAHWLERYSTVKAESSID

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=347, Percent_Identity=26.8011527377522, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1789463, Length=334, Percent_Identity=26.0479041916168, Blast_Score=104, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17540738, Length=297, Percent_Identity=28.6195286195286, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17559802, Length=282, Percent_Identity=28.0141843971631, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17565138, Length=267, Percent_Identity=26.9662921348315, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI72001454, Length=343, Percent_Identity=26.2390670553936, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17559804, Length=274, Percent_Identity=28.4671532846715, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17564188, Length=298, Percent_Identity=26.510067114094, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17566914, Length=267, Percent_Identity=28.0898876404494, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6325086, Length=229, Percent_Identity=27.9475982532751, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6321973, Length=237, Percent_Identity=29.957805907173, Blast_Score=95, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 40664; Mature: 40533

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQLFSPFRLKDITLKNRIAVAPMCQYQAHDGLSNDWHQVHYTSLARGGAGLVVVEATAV
CCCCCCCCCEEEEEECCCEEECCHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEEEEEEE
SPEGRITPRCLGLWNEEQAAGLANIASAIKGAGAVAGIQIAHAGRKASANIPWEGDDHIE
CCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCHHEEEEEECCCCCCCCCCCCCCCCCC
GDEGWQTLSPSAVAFGANLGKVPTAMTIDDIQRVKADFVAAAKRALEAGFEWLELHFAHG
CCCCCCCCCCCCEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
YLAQSFFSTYANQRTDEYGGDAQGRGRFLIETVEAVRAVWPEHLPLTARFGVIEFDDKDE
HHHHHHHHHHHHCCCHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCEEEECCCHH
QTLSESIALVKQFKRAGLDMLNVSICFSTPTANIPWRPAFLAPIAERVRREVGFPVATSW
HHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEECC
GMDNPHHAEQAIQDQQMDLVMIGKAFLANPHWPYQAAQTLKVSRPSWVLPSSYAHWLERY
CCCCCHHHHHHHHHHCCCEEEECHHHHCCCCCCHHHHHHEECCCCCEECCHHHHHHHHHH
STVKAESSID
HHHCCCCCCC
>Mature Secondary Structure 
TQLFSPFRLKDITLKNRIAVAPMCQYQAHDGLSNDWHQVHYTSLARGGAGLVVVEATAV
CCCCCCCCEEEEEECCCEEECCHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEEEEEEE
SPEGRITPRCLGLWNEEQAAGLANIASAIKGAGAVAGIQIAHAGRKASANIPWEGDDHIE
CCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCHHEEEEEECCCCCCCCCCCCCCCCCC
GDEGWQTLSPSAVAFGANLGKVPTAMTIDDIQRVKADFVAAAKRALEAGFEWLELHFAHG
CCCCCCCCCCCCEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
YLAQSFFSTYANQRTDEYGGDAQGRGRFLIETVEAVRAVWPEHLPLTARFGVIEFDDKDE
HHHHHHHHHHHHCCCHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCEEEECCCHH
QTLSESIALVKQFKRAGLDMLNVSICFSTPTANIPWRPAFLAPIAERVRREVGFPVATSW
HHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEECC
GMDNPHHAEQAIQDQQMDLVMIGKAFLANPHWPYQAAQTLKVSRPSWVLPSSYAHWLERY
CCCCCHHHHHHHHHHCCCEEEECHHHHCCCCCCHHHHHHEECCCCCEECCHHHHHHHHHH
STVKAESSID
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA