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The map label for this gene is ligA [H]

Identifier: 117920844

GI number: 117920844

Start: 2879692

End: 2880606

Strand: Reverse

Name: ligA [H]

Synonym: Shewana3_2401

Alternate gene names: 117920844

Gene position: 2880606-2879692 (Counterclockwise)

Preceding gene: 117920846

Following gene: 117920843

Centisome position: 57.93

GC content: 49.18

Gene sequence:

>915_bases
ATGACTCTTACAACTCGCTTACAATTTTTAACATTTGCATTTGTGCTGCGTGTCGCTGTTTTCTTCGGTCTTTACTGCGG
AATTTGCGGCTTATTCATGGCTGTGAGTGACGCCAATCCCGAAGCACCGAATATTCAATTAGCGACAGAGTTTTCAAAGG
AGAAGAGTGCCCACATCAGTGATTTTCTTGTCAGCGAAAAACTCGATGGTGTGCGCGGTTATTGGGATGGCAAACGCTTA
ATGACTCGTCAGGGCAATCCCATCTTAGCGCCTAGTTGGTTTACTGCGGATTTTCCGCCCACCCCGATGGACGGTGAATT
ATGGCTCGGGCGAGGGCGGTTTGAGGCCATATCAGGGCTGATTCGCCAAGCGTCCGCGAATGAGAGCGAGTGGCAGAATG
TGCGTTTTATGGTGTTTGATTTACCCAAGGCGCAAGGGAGTTTTGCAGCGCGGTATCAGCAGATGCAAACCTTGATTGCA
GGTAAATCGGTTTACCTGCAAGTGATTGAACAAGTGAGCGTAGAAAGTGTCGAGGCGCTGTATCAGAAATTAGACACCTT
AGTGGCTCAGGGTGGTGAAGGCTTAATCCTGCATCGACGCACGGCGTTATATACGCCGGGTCGTAATCCTAACGTGATGA
AGTTAAAGCCCTATTTAGATGCTGAGGCCAAAGTGATTGGCCATATAGCGGGTAAAGGACAGTTTGCCGGGCAACTGGGC
GCATTGAGAGTGCAAACAGCTGATGGCCGTGTTTTTAGTATTGGCACGGGTTTTAGCTTGGCCGAGCGTCAGCATCCGCC
CGCGATTGGTACGCTTATCACTTACAAATATCTTGGATTAACCGTCAATGGCTTACCGCGCTTTGCGAGCTTCTTGCGGA
TAAGAAGTGACATGCCGCCAGAGAATAAAGAATAG

Upstream 100 bases:

>100_bases
AGTCCTGCTAGGGTGTTACCTGACAGTGGTCGTATTCGCGGCGAATAAATCTTAAGACTAAGCTTGAAGCTCAATACCGC
TTTAATGAAGAGGCAAAGGA

Downstream 100 bases:

>100_bases
GTTGCGAAATTGTTGGTTTTTGATAAAGATCGAATGCTTAACAACAGTTTTGCCGGGTATCGTATTGATTATTAATGGGC
AATCATATCAAGGAGTGAGT

Product: DNA ligase

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MTLTTRLQFLTFAFVLRVAVFFGLYCGICGLFMAVSDANPEAPNIQLATEFSKEKSAHISDFLVSEKLDGVRGYWDGKRL
MTRQGNPILAPSWFTADFPPTPMDGELWLGRGRFEAISGLIRQASANESEWQNVRFMVFDLPKAQGSFAARYQQMQTLIA
GKSVYLQVIEQVSVESVEALYQKLDTLVAQGGEGLILHRRTALYTPGRNPNVMKLKPYLDAEAKVIGHIAGKGQFAGQLG
ALRVQTADGRVFSIGTGFSLAERQHPPAIGTLITYKYLGLTVNGLPRFASFLRIRSDMPPENKE

Sequences:

>Translated_304_residues
MTLTTRLQFLTFAFVLRVAVFFGLYCGICGLFMAVSDANPEAPNIQLATEFSKEKSAHISDFLVSEKLDGVRGYWDGKRL
MTRQGNPILAPSWFTADFPPTPMDGELWLGRGRFEAISGLIRQASANESEWQNVRFMVFDLPKAQGSFAARYQQMQTLIA
GKSVYLQVIEQVSVESVEALYQKLDTLVAQGGEGLILHRRTALYTPGRNPNVMKLKPYLDAEAKVIGHIAGKGQFAGQLG
ALRVQTADGRVFSIGTGFSLAERQHPPAIGTLITYKYLGLTVNGLPRFASFLRIRSDMPPENKE
>Mature_303_residues
TLTTRLQFLTFAFVLRVAVFFGLYCGICGLFMAVSDANPEAPNIQLATEFSKEKSAHISDFLVSEKLDGVRGYWDGKRLM
TRQGNPILAPSWFTADFPPTPMDGELWLGRGRFEAISGLIRQASANESEWQNVRFMVFDLPKAQGSFAARYQQMQTLIAG
KSVYLQVIEQVSVESVEALYQKLDTLVAQGGEGLILHRRTALYTPGRNPNVMKLKPYLDAEAKVIGHIAGKGQFAGQLGA
LRVQTADGRVFSIGTGFSLAERQHPPAIGTLITYKYLGLTVNGLPRFASFLRIRSDMPPENKE

Specific function: Catalyzes efficient strand joining on a single nicked DNA [H]

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF01068 DNA_ligase_A_M [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 33659; Mature: 33528

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTTRLQFLTFAFVLRVAVFFGLYCGICGLFMAVSDANPEAPNIQLATEFSKEKSAHIS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHCHHHHHHHH
DFLVSEKLDGVRGYWDGKRLMTRQGNPILAPSWFTADFPPTPMDGELWLGRGRFEAISGL
HHHHHHHCCCCCCEECCCHHEECCCCEEECCCCEECCCCCCCCCCCEEECCCHHHHHHHH
IRQASANESEWQNVRFMVFDLPKAQGSFAARYQQMQTLIAGKSVYLQVIEQVSVESVEAL
HHHCCCCCCHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
YQKLDTLVAQGGEGLILHRRTALYTPGRNPNVMKLKPYLDAEAKVIGHIAGKGQFAGQLG
HHHHHHHHHCCCCEEEEEECEEEECCCCCCCEEEECCCCCCCHHHEEECCCCCCCCCCCC
ALRVQTADGRVFSIGTGFSLAERQHPPAIGTLITYKYLGLTVNGLPRFASFLRIRSDMPP
EEEEEECCCEEEEEECCCCHHHHCCCCCHHHHHHHHHHCEEECCHHHHHHHHHHHCCCCC
ENKE
CCCC
>Mature Secondary Structure 
TLTTRLQFLTFAFVLRVAVFFGLYCGICGLFMAVSDANPEAPNIQLATEFSKEKSAHIS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHCHHHHHHHH
DFLVSEKLDGVRGYWDGKRLMTRQGNPILAPSWFTADFPPTPMDGELWLGRGRFEAISGL
HHHHHHHCCCCCCEECCCHHEECCCCEEECCCCEECCCCCCCCCCCEEECCCHHHHHHHH
IRQASANESEWQNVRFMVFDLPKAQGSFAARYQQMQTLIAGKSVYLQVIEQVSVESVEAL
HHHCCCCCCHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
YQKLDTLVAQGGEGLILHRRTALYTPGRNPNVMKLKPYLDAEAKVIGHIAGKGQFAGQLG
HHHHHHHHHCCCCEEEEEECEEEECCCCCCCEEEECCCCCCCHHHEEECCCCCCCCCCCC
ALRVQTADGRVFSIGTGFSLAERQHPPAIGTLITYKYLGLTVNGLPRFASFLRIRSDMPP
EEEEEECCCEEEEEECCCCHHHHCCCCCHHHHHHHHHHCEEECCHHHHHHHHHHHCCCCC
ENKE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550458; 7542800; 9060431 [H]