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The map label for this gene is cvrA [H]

Identifier: 117920767

GI number: 117920767

Start: 2798036

End: 2800048

Strand: Reverse

Name: cvrA [H]

Synonym: Shewana3_2324

Alternate gene names: 117920767

Gene position: 2800048-2798036 (Counterclockwise)

Preceding gene: 117920768

Following gene: 117920765

Centisome position: 56.31

GC content: 49.03

Gene sequence:

>2013_bases
ATGGTTGAAAAAATCACTGGGATGTTAGCACTCATCGGGGTGCTTTCGTTATTTTGTCAATGGGTTGGTTGGAAGCTTAG
ATTACCTGCAATTTTACCCTTATTACTCTGTGGTTTGATGTTAGGCCCGGCATTTGGGGTGCTCAATCCCGATGAAATCT
TTGGGGATTTATTGTTTCCTATCATTTCACTCGGTGTAGCCGTGATCCTGTTTGAGGGCGCATTGACCCTCAATTTTAAA
GAGATAAAAGATCATGGTCGCATGGTGACGCACTTAGTGAGCATCGGCATGGTGATCACTTGGGGCTGTATCAGTGTCGC
GACCTTTTACCTACTGAATTTTAGCTGGGAGGTCGCACTGTTATTTGGCGCCCTCGTGGTGGTCACAGGCCCGACCGTGA
TAGTACCTATGCTGCGCAGCGTACGGCCTAAGTCGCAACTGGCGAGTATTTTACGCTGGGAAGGGATTGTGATTGACCCG
ATTGGTGCGCTACTTGCTGTATTAGTCTTTGAATACATTACGGTGTCTGGCGATCCCACTAGCCATGTGCTCTATGCACT
AGGCTCCATGCTCACGCTTGGCTTAGGCTTAGGTGCGGCGTCAGGTTACTTAATTGGCCAAGTGATCCGCCGTAATTTAT
TGCCGCATTATTTACGAAATACCGCAGTATTAACCCTTATGCTGGGGATTTTCGTCGGCTCCAACCTACTGCAGGAAGAG
TCGGGGTTACTCACTGTGACTGTGATGGGGATTTGGCTGGCGAATATGCGCGGTGTGGATATTGCTGAAATCCTTGAATT
TAAAGAGACACTGACAGTGCTGTTGATCTCGGCCTTATTTATCCTGTTAGCTGCCAGACTCGACTCGAATGCCATGATGG
ATTTAGGTTGGGGCGGGGTAGGCGTACTCGCCGTGACTATGCTGGTTGCGCGGCCGCTCAGTATTTGGGTGTCGGGCATT
GGGACGTCACTATCAAAGGCCGATAAGTGGTTCCTATGTTGGATTGCGCCGCGGGGGATTGTGGCGGCGGCGGTATCTTC
CTTATTCGCCATTAAGTTAGAGGCAACCAATGTGCAGGGCGCCGATGCCATTGTACCCTTAGTGTTTTTAATTATTATCG
GCACTGTGGTTATCCAAAGTTTAACTGCGGGCCGCTGGGCGAAATACCTTGGGGTGACCTCGGGGTCGGCGCAAGGATTA
TTAATCTTTGGCGCCTCCAAATTTTCCCGCGAGCTAGCAAAAATCTTAAAGGCCAAAGATATCAAAGTGCTGCTGGCCGA
CAGCAACTGGGATAACATTCGCCTCGCGCGGATGGACAATATTCCGGTCTATTTTGGTAATCCTGCCTCTGAACATGCTG
AAACCTATATGGATTTAACTGGGATTGGCCGAGTGCTGATCATGTCGCCTTATAAGCAGTTAAACCCGCTGGTGACCTTT
TATTTTCAAGATGTATTAGGTTCTAAAAAGGTCTTTGGCCTTAACAATGCCGAGCAGGGCAGCGCGCGCCATCAATTATC
AGAGACTTACAAACAGCGATTGTGTTTGTTTGGTGATGCCGTGTCCTACGCCAAAATTGCCAGTCAAATGGCGAAAGGGG
CACAGCTTAAAGTCACTAACTTAACTGAAAACTTCACCTTCGAGCATTTCCGCAAACGTTATGGCGAAACGGCATTGCCG
TTAGTGTATTTGACCAAAGAAGGCAAAGTCGTGATTGTGTCAGGTAATGACACCCAATTCCCCAATGGCATCGAGTTAAT
CAGCCTATTGCCCGTTGAGGCGCTTGAAGAAGCGAAAATTCAACAGGCGATTGCCGAGCAAGAGGTGATAGCTGCTCAGG
CCAAAGCGGCGGAAGAAGCGGCTCTAGCGAAAGCCAAGGCCGAGGAGGAAGCTGAAGCTGAGCGCCAACGACTTGAGCAG
CAAGCGAAAACTAAGGCTGATGAGCCATCACAACCTGAAGCTGACGTACAAGATAACATCAATACCTCGGATGAAACGTT
GGCGAAGGGATAA

Upstream 100 bases:

>100_bases
TTGCTGCTATTGTTATCACCAATAGTTCATTTTTCTGTATGAAAAAAGCGTGTTAGGTTGAGTTAATACTGACCACTCCA
TACCAACTAAAGGAAGTTAT

Downstream 100 bases:

>100_bases
TGGACAAGGCCAAGGTTAACTCAGGTGAGCTTGGCAATTGCGAAGAGATAAGCCTGTGAGGCGAAAATAAAAAAGGCACT
ACATAGGTAGTGCCTTTTTG

Product: sodium/hydrogen exchanger

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 670; Mature: 670

Protein sequence:

>670_residues
MVEKITGMLALIGVLSLFCQWVGWKLRLPAILPLLLCGLMLGPAFGVLNPDEIFGDLLFPIISLGVAVILFEGALTLNFK
EIKDHGRMVTHLVSIGMVITWGCISVATFYLLNFSWEVALLFGALVVVTGPTVIVPMLRSVRPKSQLASILRWEGIVIDP
IGALLAVLVFEYITVSGDPTSHVLYALGSMLTLGLGLGAASGYLIGQVIRRNLLPHYLRNTAVLTLMLGIFVGSNLLQEE
SGLLTVTVMGIWLANMRGVDIAEILEFKETLTVLLISALFILLAARLDSNAMMDLGWGGVGVLAVTMLVARPLSIWVSGI
GTSLSKADKWFLCWIAPRGIVAAAVSSLFAIKLEATNVQGADAIVPLVFLIIIGTVVIQSLTAGRWAKYLGVTSGSAQGL
LIFGASKFSRELAKILKAKDIKVLLADSNWDNIRLARMDNIPVYFGNPASEHAETYMDLTGIGRVLIMSPYKQLNPLVTF
YFQDVLGSKKVFGLNNAEQGSARHQLSETYKQRLCLFGDAVSYAKIASQMAKGAQLKVTNLTENFTFEHFRKRYGETALP
LVYLTKEGKVVIVSGNDTQFPNGIELISLLPVEALEEAKIQQAIAEQEVIAAQAKAAEEAALAKAKAEEEAEAERQRLEQ
QAKTKADEPSQPEADVQDNINTSDETLAKG

Sequences:

>Translated_670_residues
MVEKITGMLALIGVLSLFCQWVGWKLRLPAILPLLLCGLMLGPAFGVLNPDEIFGDLLFPIISLGVAVILFEGALTLNFK
EIKDHGRMVTHLVSIGMVITWGCISVATFYLLNFSWEVALLFGALVVVTGPTVIVPMLRSVRPKSQLASILRWEGIVIDP
IGALLAVLVFEYITVSGDPTSHVLYALGSMLTLGLGLGAASGYLIGQVIRRNLLPHYLRNTAVLTLMLGIFVGSNLLQEE
SGLLTVTVMGIWLANMRGVDIAEILEFKETLTVLLISALFILLAARLDSNAMMDLGWGGVGVLAVTMLVARPLSIWVSGI
GTSLSKADKWFLCWIAPRGIVAAAVSSLFAIKLEATNVQGADAIVPLVFLIIIGTVVIQSLTAGRWAKYLGVTSGSAQGL
LIFGASKFSRELAKILKAKDIKVLLADSNWDNIRLARMDNIPVYFGNPASEHAETYMDLTGIGRVLIMSPYKQLNPLVTF
YFQDVLGSKKVFGLNNAEQGSARHQLSETYKQRLCLFGDAVSYAKIASQMAKGAQLKVTNLTENFTFEHFRKRYGETALP
LVYLTKEGKVVIVSGNDTQFPNGIELISLLPVEALEEAKIQQAIAEQEVIAAQAKAAEEAALAKAKAEEEAEAERQRLEQ
QAKTKADEPSQPEADVQDNINTSDETLAKG
>Mature_670_residues
MVEKITGMLALIGVLSLFCQWVGWKLRLPAILPLLLCGLMLGPAFGVLNPDEIFGDLLFPIISLGVAVILFEGALTLNFK
EIKDHGRMVTHLVSIGMVITWGCISVATFYLLNFSWEVALLFGALVVVTGPTVIVPMLRSVRPKSQLASILRWEGIVIDP
IGALLAVLVFEYITVSGDPTSHVLYALGSMLTLGLGLGAASGYLIGQVIRRNLLPHYLRNTAVLTLMLGIFVGSNLLQEE
SGLLTVTVMGIWLANMRGVDIAEILEFKETLTVLLISALFILLAARLDSNAMMDLGWGGVGVLAVTMLVARPLSIWVSGI
GTSLSKADKWFLCWIAPRGIVAAAVSSLFAIKLEATNVQGADAIVPLVFLIIIGTVVIQSLTAGRWAKYLGVTSGSAQGL
LIFGASKFSRELAKILKAKDIKVLLADSNWDNIRLARMDNIPVYFGNPASEHAETYMDLTGIGRVLIMSPYKQLNPLVTF
YFQDVLGSKKVFGLNNAEQGSARHQLSETYKQRLCLFGDAVSYAKIASQMAKGAQLKVTNLTENFTFEHFRKRYGETALP
LVYLTKEGKVVIVSGNDTQFPNGIELISLLPVEALEEAKIQQAIAEQEVIAAQAKAAEEAALAKAKAEEEAEAERQRLEQ
QAKTKADEPSQPEADVQDNINTSDETLAKG

Specific function: Participates in control of cell volume in low-osmolarity conditions [H]

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR016169
- InterPro:   IPR006037
- InterPro:   IPR005170 [H]

Pfam domain/function: PF03471 CorC_HlyC; PF00999 Na_H_Exchanger; PF02080 TrkA_C [H]

EC number: NA

Molecular weight: Translated: 72631; Mature: 72631

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCHHHCCC
>Mature Secondary Structure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CCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]