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The map label for this gene is 117920574

Identifier: 117920574

GI number: 117920574

Start: 2555501

End: 2556478

Strand: Reverse

Name: 117920574

Synonym: Shewana3_2130

Alternate gene names: NA

Gene position: 2556478-2555501 (Counterclockwise)

Preceding gene: 117920575

Following gene: 117920573

Centisome position: 51.42

GC content: 49.59

Gene sequence:

>978_bases
GTGGCAGAAATGAATATGTTACAGGCCGTCAATGAGGCCTTGTCTATCGCCATGCAATCTGACGAGCGCATGGTGGTATT
TGGTGAAGACGTTGGCCACTTTGGCGGTGTGTTTCGCGCAACCTCAGGTTTACAGGAAAAGTTTGGTCGCAGCCGTTGCT
TTAACACGCCGCTGACTGAACAAGGCATTGCGGGTTTTGCCAACGGTTTAGCCTCTAATGGCATGACCGCCGTAGCGGAA
ATCCAGTTCGCCGATTACATCTTTCCAGCGTTCGATCAGATAGTGAACGAGTCTGCTAAATTCCGTTACCGCAGTGGTAA
TGAATTTAATGTGGGAAGCCTAGTGTTTCGTACACCTTATGGTGGCGGTATTGCGGGCGGCCATTATCATTCACAATCGC
CAGAAGCTTATTTTACCCAAACCCCAGGCTTAAAAGTGGTTGTGCCACGCAATCCAGAGCAGGCCAAGGGCTTATTATTA
GCCTCTATTCGCGATAAAAACCCTGTGGTGTTCTTCGAGCCAAAGCGTTTATACCGTGCTTCAGTGGGTGAAGTCCCTGC
GGGCGATTATGAAATCGAGCTGGGTAAAGCCGAAGTAGTGCGTGAAGGGAAAGACATCACCTTAGTAGCCTGGGGCGCAC
AGATGGAAATCATCGAAAAAGCGGCCGACATGGCGGCAAAAGAGGGGATTTCCTGCGAAATTATCGACCTACGTACACTC
GCGCCTTGGGATGTAGATACAGTTGCAGATTCTGTGAAGAAGACAGGCCGCTTACTGATCAACCACGAAGCGCCATTGAC
GGGTGGTTTTGCCGGTGAAATCGCCGCGACGATTCAGCAAGAGTGTTTCTTGTATTTAGAATCACCCATCAGCCGTGTAT
GTGGTCTAGATACCCCATATCCACTGGTCCACGAAAAAGAATATATGCCCGATGCGCTCAAAACCTTTGAAGCCATTAAG
GCATCGGTGAACTTCTAG

Upstream 100 bases:

>100_bases
CAAGCCAACACCAGCGCTGAAAAAGCAGCTGAGTGAACTTAAAGAACACATCAAGAAATATCCGCAATCCTATCCCAAAA
GTGCAGGGAGGCTATAAGCC

Downstream 100 bases:

>100_bases
GAGTCCGGTATGATTAAAGATTTTATTTTGCCGGACATTGGTGAAGGCGTTGTCGAGTGCGAACTCGTCGAGTGGTTGGT
GCAAGAGGGCGACACGATTG

Product: transketolase, central region

Products: NA

Alternate protein names: Branched-chain alpha-keto acid dehydrogenase E1 component beta chain; BCKDH E1-beta [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MAEMNMLQAVNEALSIAMQSDERMVVFGEDVGHFGGVFRATSGLQEKFGRSRCFNTPLTEQGIAGFANGLASNGMTAVAE
IQFADYIFPAFDQIVNESAKFRYRSGNEFNVGSLVFRTPYGGGIAGGHYHSQSPEAYFTQTPGLKVVVPRNPEQAKGLLL
ASIRDKNPVVFFEPKRLYRASVGEVPAGDYEIELGKAEVVREGKDITLVAWGAQMEIIEKAADMAAKEGISCEIIDLRTL
APWDVDTVADSVKKTGRLLINHEAPLTGGFAGEIAATIQQECFLYLESPISRVCGLDTPYPLVHEKEYMPDALKTFEAIK
ASVNF

Sequences:

>Translated_325_residues
MAEMNMLQAVNEALSIAMQSDERMVVFGEDVGHFGGVFRATSGLQEKFGRSRCFNTPLTEQGIAGFANGLASNGMTAVAE
IQFADYIFPAFDQIVNESAKFRYRSGNEFNVGSLVFRTPYGGGIAGGHYHSQSPEAYFTQTPGLKVVVPRNPEQAKGLLL
ASIRDKNPVVFFEPKRLYRASVGEVPAGDYEIELGKAEVVREGKDITLVAWGAQMEIIEKAADMAAKEGISCEIIDLRTL
APWDVDTVADSVKKTGRLLINHEAPLTGGFAGEIAATIQQECFLYLESPISRVCGLDTPYPLVHEKEYMPDALKTFEAIK
ASVNF
>Mature_324_residues
AEMNMLQAVNEALSIAMQSDERMVVFGEDVGHFGGVFRATSGLQEKFGRSRCFNTPLTEQGIAGFANGLASNGMTAVAEI
QFADYIFPAFDQIVNESAKFRYRSGNEFNVGSLVFRTPYGGGIAGGHYHSQSPEAYFTQTPGLKVVVPRNPEQAKGLLLA
SIRDKNPVVFFEPKRLYRASVGEVPAGDYEIELGKAEVVREGKDITLVAWGAQMEIIEKAADMAAKEGISCEIIDLRTLA
PWDVDTVADSVKKTGRLLINHEAPLTGGFAGEIAATIQQECFLYLESPISRVCGLDTPYPLVHEKEYMPDALKTFEAIKA
SVNF

Specific function: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components:branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltran

COG id: COG0022

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4557353, Length=324, Percent_Identity=61.7283950617284, Blast_Score=428, Evalue=1e-120,
Organism=Homo sapiens, GI34101272, Length=324, Percent_Identity=61.7283950617284, Blast_Score=428, Evalue=1e-120,
Organism=Homo sapiens, GI156564403, Length=329, Percent_Identity=34.6504559270517, Blast_Score=197, Evalue=8e-51,
Organism=Homo sapiens, GI291084858, Length=329, Percent_Identity=32.8267477203647, Blast_Score=183, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17506935, Length=325, Percent_Identity=61.2307692307692, Blast_Score=395, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17538422, Length=328, Percent_Identity=37.1951219512195, Blast_Score=207, Evalue=5e-54,
Organism=Saccharomyces cerevisiae, GI6319698, Length=324, Percent_Identity=35.4938271604938, Blast_Score=199, Evalue=4e-52,
Organism=Drosophila melanogaster, GI160714828, Length=324, Percent_Identity=58.0246913580247, Blast_Score=399, Evalue=1e-111,
Organism=Drosophila melanogaster, GI160714832, Length=324, Percent_Identity=58.0246913580247, Blast_Score=399, Evalue=1e-111,
Organism=Drosophila melanogaster, GI21358145, Length=303, Percent_Identity=37.953795379538, Blast_Score=204, Evalue=5e-53,
Organism=Drosophila melanogaster, GI24650940, Length=303, Percent_Identity=37.953795379538, Blast_Score=204, Evalue=5e-53,
Organism=Drosophila melanogaster, GI160714826, Length=65, Percent_Identity=52.3076923076923, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24650943, Length=91, Percent_Identity=34.0659340659341, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24650945, Length=91, Percent_Identity=34.0659340659341, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005476 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: =1.2.4.4 [H]

Molecular weight: Translated: 35478; Mature: 35347

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEMNMLQAVNEALSIAMQSDERMVVFGEDVGHFGGVFRATSGLQEKFGRSRCFNTPLTE
CCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHCHHHHHHHHHHHHHCHHHCCCCCCCH
QGIAGFANGLASNGMTAVAEIQFADYIFPAFDQIVNESAKFRYRSGNEFNVGSLVFRTPY
HHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEEEECCC
GGGIAGGHYHSQSPEAYFTQTPGLKVVVPRNPEQAKGLLLASIRDKNPVVFFEPKRLYRA
CCCCCCCCCCCCCCCEEEECCCCEEEEECCCCHHHCCEEEEEECCCCCEEEECCHHHHHH
SVGEVPAGDYEIELGKAEVVREGKDITLVAWGAQMEIIEKAADMAAKEGISCEIIDLRTL
CCCCCCCCCEEEEECHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEECCC
APWDVDTVADSVKKTGRLLINHEAPLTGGFAGEIAATIQQECFLYLESPISRVCGLDTPY
CCCCHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PLVHEKEYMPDALKTFEAIKASVNF
CCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AEMNMLQAVNEALSIAMQSDERMVVFGEDVGHFGGVFRATSGLQEKFGRSRCFNTPLTE
CCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHCHHHHHHHHHHHHHCHHHCCCCCCCH
QGIAGFANGLASNGMTAVAEIQFADYIFPAFDQIVNESAKFRYRSGNEFNVGSLVFRTPY
HHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEEEECCC
GGGIAGGHYHSQSPEAYFTQTPGLKVVVPRNPEQAKGLLLASIRDKNPVVFFEPKRLYRA
CCCCCCCCCCCCCCCEEEECCCCEEEEECCCCHHHCCEEEEEECCCCCEEEECCHHHHHH
SVGEVPAGDYEIELGKAEVVREGKDITLVAWGAQMEIIEKAADMAAKEGISCEIIDLRTL
CCCCCCCCCEEEEECHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEECCC
APWDVDTVADSVKKTGRLLINHEAPLTGGFAGEIAATIQQECFLYLESPISRVCGLDTPY
CCCCHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PLVHEKEYMPDALKTFEAIKASVNF
CCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA