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The map label for this gene is cpxR [H]

Identifier: 117920404

GI number: 117920404

Start: 2333086

End: 2333766

Strand: Direct

Name: cpxR [H]

Synonym: Shewana3_1959

Alternate gene names: 117920404

Gene position: 2333086-2333766 (Clockwise)

Preceding gene: 117920403

Following gene: 117920405

Centisome position: 46.92

GC content: 45.96

Gene sequence:

>681_bases
ATGAGTAAAATACTGTTAGTCGATGATGATCCATTATTCAGAGTTTGGTTAACTGAAGCGCTTAAAGCACAGGGACATGA
AGTTGAATGTGCCGTAAACGGCGTTGAAGGGCTCAAACGTATTCGCAGCTTTAGGCCTGATATTATTATGCTCGATCTGG
TGATGCCGCAAATGGATGGTTTCTCACTACTAGAGGCGAGGGACTGTATAACGCCTATCATGATGTTATCTGCCCGTGAT
AATGAGGCTGACAGGATCCGAAGCTACGAGCTTGGTGCGGATGATTTCTTAACGAAACCCTTTAGCATTAGAGAGTTATT
GGTGCGTTTGCATGCCTTAGAGCGTCGATTAATCCCGCGCGCCACAGAGCCAATGGCAATCGAGCAGGCGACAATCCAGC
CGGTCAAATTCGATGAGGCTGCTTATAGGATCACTATTGGTAAAAATGCCGTGGAGCTCACCCAAACCGAGTTTAGGTTG
TTTAAGTATCTGTTCGAGCGTAAGGGGCAAGTGATCACTAAGCAAGAGCTGCAAAAATCCGTATTGCAGAAGGACTTAGG
CCGTTTTGATCGTAACTTGGATATGCATATTAGTAATACAAGGCGCAAACTGGCGAATACCCGTTTACCGCGGACATTAA
TCAATACGGTCCGTGGTCAAGGGTACAGTTTTTCCGCTTGA

Upstream 100 bases:

>100_bases
CAATTAAGCGAATACTGATTTTTAATCATCTTCTAATGCTAGAGACATATTTTAAGTTATGGTAACATAAATGATATTGA
TTCTCGTTTGGTGTTTAGGG

Downstream 100 bases:

>100_bases
TGTGTTGTGAGAGGTTAACAAACTAGGCACTGATGAATTACAGTGCGACTGCTGGCTTCTTAGGCAATTTTAGTCGCTTT
CATTTTCCCCTGATACGGAT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MSKILLVDDDPLFRVWLTEALKAQGHEVECAVNGVEGLKRIRSFRPDIIMLDLVMPQMDGFSLLEARDCITPIMMLSARD
NEADRIRSYELGADDFLTKPFSIRELLVRLHALERRLIPRATEPMAIEQATIQPVKFDEAAYRITIGKNAVELTQTEFRL
FKYLFERKGQVITKQELQKSVLQKDLGRFDRNLDMHISNTRRKLANTRLPRTLINTVRGQGYSFSA

Sequences:

>Translated_226_residues
MSKILLVDDDPLFRVWLTEALKAQGHEVECAVNGVEGLKRIRSFRPDIIMLDLVMPQMDGFSLLEARDCITPIMMLSARD
NEADRIRSYELGADDFLTKPFSIRELLVRLHALERRLIPRATEPMAIEQATIQPVKFDEAAYRITIGKNAVELTQTEFRL
FKYLFERKGQVITKQELQKSVLQKDLGRFDRNLDMHISNTRRKLANTRLPRTLINTVRGQGYSFSA
>Mature_225_residues
SKILLVDDDPLFRVWLTEALKAQGHEVECAVNGVEGLKRIRSFRPDIIMLDLVMPQMDGFSLLEARDCITPIMMLSARDN
EADRIRSYELGADDFLTKPFSIRELLVRLHALERRLIPRATEPMAIEQATIQPVKFDEAAYRITIGKNAVELTQTEFRLF
KYLFERKGQVITKQELQKSVLQKDLGRFDRNLDMHISNTRRKLANTRLPRTLINTVRGQGYSFSA

Specific function: Member of a two-component regulatory system [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=37.9310344827586, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=32.1739130434783, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=32.7433628318584, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=34.8214285714286, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=30.6666666666667, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=30.8370044052863, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1786911, Length=230, Percent_Identity=35.2173913043478, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=30.4721030042918, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=29.5964125560538, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=31.2775330396476, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=32.3404255319149, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=28.1938325991189, Blast_Score=94, Evalue=5e-21,
Organism=Escherichia coli, GI1787229, Length=236, Percent_Identity=26.6949152542373, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=25.5230125523013, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=33.0275229357798, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787487, Length=101, Percent_Identity=36.6336633663366, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790299, Length=105, Percent_Identity=35.2380952380952, Blast_Score=68, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6322000, Length=132, Percent_Identity=29.5454545454545, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26082; Mature: 25951

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKILLVDDDPLFRVWLTEALKAQGHEVECAVNGVEGLKRIRSFRPDIIMLDLVMPQMDG
CCEEEEECCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHCCCCEEEEEEHHCCCCC
FSLLEARDCITPIMMLSARDNEADRIRSYELGADDFLTKPFSIRELLVRLHALERRLIPR
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCC
ATEPMAIEQATIQPVKFDEAAYRITIGKNAVELTQTEFRLFKYLFERKGQVITKQELQKS
CCCCCEEHHHHCCCEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCEECHHHHHHH
VLQKDLGRFDRNLDMHISNTRRKLANTRLPRTLINTVRGQGYSFSA
HHHHHHHHHCCCCCEEEHHHHHHHHHCCCCHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SKILLVDDDPLFRVWLTEALKAQGHEVECAVNGVEGLKRIRSFRPDIIMLDLVMPQMDG
CEEEEECCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHCCCCEEEEEEHHCCCCC
FSLLEARDCITPIMMLSARDNEADRIRSYELGADDFLTKPFSIRELLVRLHALERRLIPR
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCC
ATEPMAIEQATIQPVKFDEAAYRITIGKNAVELTQTEFRLFKYLFERKGQVITKQELQKS
CCCCCEEHHHHCCCEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCEECHHHHHHH
VLQKDLGRFDRNLDMHISNTRRKLANTRLPRTLINTVRGQGYSFSA
HHHHHHHHHCCCCCEEEHHHHHHHHHCCCCHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]