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The map label for this gene is yfhA [H]

Identifier: 117920258

GI number: 117920258

Start: 2136712

End: 2138136

Strand: Direct

Name: yfhA [H]

Synonym: Shewana3_1811

Alternate gene names: 117920258

Gene position: 2136712-2138136 (Clockwise)

Preceding gene: 117920256

Following gene: 117920259

Centisome position: 42.97

GC content: 42.18

Gene sequence:

>1425_bases
ATGACTGGCCCTATATGGGCGACAGTATCTGATGTGACCTTTGATCGGCTTGAGCTTATTTACAATTATCCGTCGGACCT
AGTTACTCCGTACCTTGAGCTACTCACTGGCAATCTGAGTTGTCCTGTCAATGCTCGTAAGGCCGATTTATCCTCGCCAG
TTGATTTCGGAGAAATTTACCTCGCTGCAGAACGGTTACTAGACGGTATTAATCGTGAAGCCATTCAACTGTCTGTTTTA
TTGAGTCCGGGTACACCTGCTATGCAGGCTGTGTGGATATTACTCGGTAAAACTCGATTCGCCTGCAACTTTTATCAAGC
ATCAAAAGAACAAGGCGTTAATATTGTAGAAATTCCTTTTAAGCTGACAGCTGAATATTTTCCTTCGATGACTAATCTAG
CCCCTATTGAACTTGGGCAACTTGGTCTATTGGGCTTTGATGCTGATCCCGCTTTTGATGACATTATTACCCTTGATCCT
GAAATGTTACTACTTAAAGCCAAGGCTCAAGTTTTAGCATCGCATGAAGTATCTGTGCTGATTTGTGGTGAGAGTGGTAC
CGGCAAAGAGATGTTTGCTCGGGCAATTCATAATGCAAGTGCGAGAAGGGACAAACCATTTGTTGCGATCAATTGTGGCG
CATTTCCCTCAGAACTTATCGATTCAATACTTTTTGGCCATAAAAAGGGGGCTTTTACTGGTGCGGTTTCAGATAAGGTA
GGAGTTTTTGAATTGGCGCATTCAGGTACTCTTTTTTTGGATGAGTTTGGCGAGCTTGATAGTTCAGCCCAAGTCAGGCT
CCTTAGAGTATTGCAAGATGGTAAATTCACTCGCTTGGGAGATAGTAAAGAACGTAGCAGCAATTTCCATTTAATCACAG
CAACTAATCGAGACTTGATGGCTGACGTTTCCAAGGGTAGGTTCAGAGAGGATTTATTCTATAGGGTTGCCATTGGTGTG
TTGTCCTTACCACCTCTAAGGTCTCGACAAAGCGATTTAGACCATCTAGCAGATCAGTTTACCGCCATGCTCACACAAGA
ATACCCTTCTCTAGGTGGTAAAAAAATTTCCACTGCTGCAAAAAAAATTATCAGTAATCATCGTTGGCCTGGAAATATCA
GAGAGCTGAAAGCAACGATTCTTAGGGCAGCCTTATGGTCTGAAACTGCCGTATTGGAAGAAGTTGATATACGCAGGGCG
ATACTTTCGACGTTCCAAAATAGTGAGAGCATTCTCGAAAGAGATATATCAAAAGGTGTTGATATAAATAGTATTATTGA
TCTAGTAGAACGGCACTATTTAGAACGAGGATTGGCATTTACGTCGGGGAATAAACGTAAAGCGGCGTTGTTACTCGGCT
ACAACAATCACCAAACTTTAAATAATCGCCTTAAAAAACTCGGTCTAGAAAACGACAATGACTAA

Upstream 100 bases:

>100_bases
ATTGATAAATTTAAATGTTGGTTTAGGGATGAACATAATTAACGAAAAAGTGTTGGTTAGTTGGATTGGTGGCAACGATT
TAGAATCAAAGGGGAGTAAA

Downstream 100 bases:

>100_bases
ATTGGCATAAAAGTCGCTATATGAGTTTGACCCTGAATTAAGCCAGGGAATGCAATTCAACATAAGGAGATCCACTGTGA
CACAATTAACGGCAATACAA

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MTGPIWATVSDVTFDRLELIYNYPSDLVTPYLELLTGNLSCPVNARKADLSSPVDFGEIYLAAERLLDGINREAIQLSVL
LSPGTPAMQAVWILLGKTRFACNFYQASKEQGVNIVEIPFKLTAEYFPSMTNLAPIELGQLGLLGFDADPAFDDIITLDP
EMLLLKAKAQVLASHEVSVLICGESGTGKEMFARAIHNASARRDKPFVAINCGAFPSELIDSILFGHKKGAFTGAVSDKV
GVFELAHSGTLFLDEFGELDSSAQVRLLRVLQDGKFTRLGDSKERSSNFHLITATNRDLMADVSKGRFREDLFYRVAIGV
LSLPPLRSRQSDLDHLADQFTAMLTQEYPSLGGKKISTAAKKIISNHRWPGNIRELKATILRAALWSETAVLEEVDIRRA
ILSTFQNSESILERDISKGVDINSIIDLVERHYLERGLAFTSGNKRKAALLLGYNNHQTLNNRLKKLGLENDND

Sequences:

>Translated_474_residues
MTGPIWATVSDVTFDRLELIYNYPSDLVTPYLELLTGNLSCPVNARKADLSSPVDFGEIYLAAERLLDGINREAIQLSVL
LSPGTPAMQAVWILLGKTRFACNFYQASKEQGVNIVEIPFKLTAEYFPSMTNLAPIELGQLGLLGFDADPAFDDIITLDP
EMLLLKAKAQVLASHEVSVLICGESGTGKEMFARAIHNASARRDKPFVAINCGAFPSELIDSILFGHKKGAFTGAVSDKV
GVFELAHSGTLFLDEFGELDSSAQVRLLRVLQDGKFTRLGDSKERSSNFHLITATNRDLMADVSKGRFREDLFYRVAIGV
LSLPPLRSRQSDLDHLADQFTAMLTQEYPSLGGKKISTAAKKIISNHRWPGNIRELKATILRAALWSETAVLEEVDIRRA
ILSTFQNSESILERDISKGVDINSIIDLVERHYLERGLAFTSGNKRKAALLLGYNNHQTLNNRLKKLGLENDND
>Mature_473_residues
TGPIWATVSDVTFDRLELIYNYPSDLVTPYLELLTGNLSCPVNARKADLSSPVDFGEIYLAAERLLDGINREAIQLSVLL
SPGTPAMQAVWILLGKTRFACNFYQASKEQGVNIVEIPFKLTAEYFPSMTNLAPIELGQLGLLGFDADPAFDDIITLDPE
MLLLKAKAQVLASHEVSVLICGESGTGKEMFARAIHNASARRDKPFVAINCGAFPSELIDSILFGHKKGAFTGAVSDKVG
VFELAHSGTLFLDEFGELDSSAQVRLLRVLQDGKFTRLGDSKERSSNFHLITATNRDLMADVSKGRFREDLFYRVAIGVL
SLPPLRSRQSDLDHLADQFTAMLTQEYPSLGGKKISTAAKKIISNHRWPGNIRELKATILRAALWSETAVLEEVDIRRAI
LSTFQNSESILERDISKGVDINSIIDLVERHYLERGLAFTSGNKRKAALLLGYNNHQTLNNRLKKLGLENDND

Specific function: Probable member of a two-component regulatory system yfhA/yfhK [H]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788905, Length=317, Percent_Identity=40.0630914826498, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI87082117, Length=321, Percent_Identity=42.0560747663551, Blast_Score=218, Evalue=8e-58,
Organism=Escherichia coli, GI1788550, Length=319, Percent_Identity=38.871473354232, Blast_Score=212, Evalue=4e-56,
Organism=Escherichia coli, GI87082152, Length=233, Percent_Identity=45.4935622317597, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI1789087, Length=249, Percent_Identity=43.7751004016064, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1790437, Length=307, Percent_Identity=39.7394136807818, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1790299, Length=337, Percent_Identity=38.2789317507418, Blast_Score=198, Evalue=6e-52,
Organism=Escherichia coli, GI1789233, Length=233, Percent_Identity=42.4892703862661, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI1787583, Length=319, Percent_Identity=35.7366771159875, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI87081872, Length=296, Percent_Identity=39.1891891891892, Blast_Score=186, Evalue=4e-48,
Organism=Escherichia coli, GI1786524, Length=246, Percent_Identity=40.650406504065, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1789828, Length=401, Percent_Identity=30.1745635910224, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI87081858, Length=312, Percent_Identity=27.8846153846154, Blast_Score=108, Evalue=6e-25,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 52404; Mature: 52272

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGPIWATVSDVTFDRLELIYNYPSDLVTPYLELLTGNLSCPVNARKADLSSPVDFGEIY
CCCCCEEEECHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHH
LAAERLLDGINREAIQLSVLLSPGTPAMQAVWILLGKTRFACNFYQASKEQGVNIVEIPF
HHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHCCHHHEEEHHHHHHHCCCEEEEECH
KLTAEYFPSMTNLAPIELGQLGLLGFDADPAFDDIITLDPEMLLLKAKAQVLASHEVSVL
HHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCEEECCHHHHHHHHHHHHHHCCCEEEE
ICGESGTGKEMFARAIHNASARRDKPFVAINCGAFPSELIDSILFGHKKGAFTGAVSDKV
EECCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCEECCCCCCC
GVFELAHSGTLFLDEFGELDSSAQVRLLRVLQDGKFTRLGDSKERSSNFHLITATNRDLM
CEEEECCCCCEEEHHHCCCCCHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEEECCCHHH
ADVSKGRFREDLFYRVAIGVLSLPPLRSRQSDLDHLADQFTAMLTQEYPSLGGKKISTAA
HHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
KKIISNHRWPGNIRELKATILRAALWSETAVLEEVDIRRAILSTFQNSESILERDISKGV
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
DINSIIDLVERHYLERGLAFTSGNKRKAALLLGYNNHQTLNNRLKKLGLENDND
CHHHHHHHHHHHHHHHCCEEECCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TGPIWATVSDVTFDRLELIYNYPSDLVTPYLELLTGNLSCPVNARKADLSSPVDFGEIY
CCCCEEEECHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHH
LAAERLLDGINREAIQLSVLLSPGTPAMQAVWILLGKTRFACNFYQASKEQGVNIVEIPF
HHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHCCHHHEEEHHHHHHHCCCEEEEECH
KLTAEYFPSMTNLAPIELGQLGLLGFDADPAFDDIITLDPEMLLLKAKAQVLASHEVSVL
HHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCEEECCHHHHHHHHHHHHHHCCCEEEE
ICGESGTGKEMFARAIHNASARRDKPFVAINCGAFPSELIDSILFGHKKGAFTGAVSDKV
EECCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCEECCCCCCC
GVFELAHSGTLFLDEFGELDSSAQVRLLRVLQDGKFTRLGDSKERSSNFHLITATNRDLM
CEEEECCCCCEEEHHHCCCCCHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEEECCCHHH
ADVSKGRFREDLFYRVAIGVLSLPPLRSRQSDLDHLADQFTAMLTQEYPSLGGKKISTAA
HHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
KKIISNHRWPGNIRELKATILRAALWSETAVLEEVDIRRAILSTFQNSESILERDISKGV
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
DINSIIDLVERHYLERGLAFTSGNKRKAALLLGYNNHQTLNNRLKKLGLENDND
CHHHHHHHHHHHHHHHCCEEECCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]