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The map label for this gene is ycfH [H]

Identifier: 117920216

GI number: 117920216

Start: 2082538

End: 2083338

Strand: Direct

Name: ycfH [H]

Synonym: Shewana3_1769

Alternate gene names: 117920216

Gene position: 2082538-2083338 (Clockwise)

Preceding gene: 117920215

Following gene: 117920218

Centisome position: 41.88

GC content: 50.44

Gene sequence:

>801_bases
GTGGAAATTGCTGTGCTTATCGATTCACATTGCCATCTCGATCGCCTGAAAGCGGCGCCCGATCAACAAACCTTAGAACT
TATCCTCGCCAACGCTAAGGCGCGCGGTGTCGACTATATGCTCTGTGTCAATGTGCGCCAGCAGGGATTCGAGTCGATGC
GTGACAAGGTTGCAGCTTTCGAACAAGTGTTTTTGTCTTCGGGCGTGCATCCGCTGGATGTGAAAGACGGCCTAGATGTT
GAGCAAATTCGCCGTTTTGCGATGGATCCGAAAGTGGTGGCCATTGGCGAAACCGGCTTAGATTATTTTTATGCCGATGA
GACCAAAGCCCTGCAACAACAGTGTTTTGAGCAACAAATTGCCTTAGCGGTTGAAGTCAATAAGCCGCTGATTGTGCATA
CCCGCGATGCCCGTGAAGACACCATCAATATGCTCAAAGCGGGGCAGGCGGACAAAGTCGGTGGCGTGTTGCATTGCTTT
ACGGAAAACTGGGAAATGGCCAAGGCGGCGATTGACTTAGGTTTTTATATTTCCGTCTCAGGCATTGTGACCTTTAAAAA
TGCCGGTGAGTTAAGAACCGTGATCCGCAAAGTGCCGAAAGAGCGTTTATTGGTGGAAACCGATTCGCCTTATCTTGCGC
CTATTCCACACCGTGGACAGGAGAATCAACCCGCCTATGTGCGTGATGTGGCTGAATTTGTGGCAGAGCTGCGCGGAGAG
CGTTACGAGGAGCTTGCCGAGTACACCAGTGAGAACTTCTTTAACTTGTTTAAGGATGCGGCCCGTTTAATCGGCCGATA
A

Upstream 100 bases:

>100_bases
TTATCCCGAGCTCAGGTTATTTAGTGCTGAGTGAAGCCTTAGCGGAATTTGACCTCGATCCCATCGCTGAGTATCCTTGT
GCTCCTTTTTGTTTCTCTGT

Downstream 100 bases:

>100_bases
GAGGTGTAACTCTTGCTTGCGCCTTGTGAGTAAAGTGGCAGTCAGTAAAGCTCGCTCTATAAAGCTAAAACCCAAAAGCT
TAACTCATTAGGCGTAAGCC

Product: TatD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MEIAVLIDSHCHLDRLKAAPDQQTLELILANAKARGVDYMLCVNVRQQGFESMRDKVAAFEQVFLSSGVHPLDVKDGLDV
EQIRRFAMDPKVVAIGETGLDYFYADETKALQQQCFEQQIALAVEVNKPLIVHTRDAREDTINMLKAGQADKVGGVLHCF
TENWEMAKAAIDLGFYISVSGIVTFKNAGELRTVIRKVPKERLLVETDSPYLAPIPHRGQENQPAYVRDVAEFVAELRGE
RYEELAEYTSENFFNLFKDAARLIGR

Sequences:

>Translated_266_residues
MEIAVLIDSHCHLDRLKAAPDQQTLELILANAKARGVDYMLCVNVRQQGFESMRDKVAAFEQVFLSSGVHPLDVKDGLDV
EQIRRFAMDPKVVAIGETGLDYFYADETKALQQQCFEQQIALAVEVNKPLIVHTRDAREDTINMLKAGQADKVGGVLHCF
TENWEMAKAAIDLGFYISVSGIVTFKNAGELRTVIRKVPKERLLVETDSPYLAPIPHRGQENQPAYVRDVAEFVAELRGE
RYEELAEYTSENFFNLFKDAARLIGR
>Mature_266_residues
MEIAVLIDSHCHLDRLKAAPDQQTLELILANAKARGVDYMLCVNVRQQGFESMRDKVAAFEQVFLSSGVHPLDVKDGLDV
EQIRRFAMDPKVVAIGETGLDYFYADETKALQQQCFEQQIALAVEVNKPLIVHTRDAREDTINMLKAGQADKVGGVLHCF
TENWEMAKAAIDLGFYISVSGIVTFKNAGELRTVIRKVPKERLLVETDSPYLAPIPHRGQENQPAYVRDVAEFVAELRGE
RYEELAEYTSENFFNLFKDAARLIGR

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=278, Percent_Identity=29.8561151079137, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI110349734, Length=278, Percent_Identity=29.8561151079137, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI226061853, Length=285, Percent_Identity=29.4736842105263, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI226061614, Length=265, Percent_Identity=29.811320754717, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI225903424, Length=128, Percent_Identity=38.28125, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI14042943, Length=193, Percent_Identity=30.0518134715026, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI225903439, Length=193, Percent_Identity=30.0518134715026, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI226061595, Length=235, Percent_Identity=29.7872340425532, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1787342, Length=259, Percent_Identity=55.5984555984556, Blast_Score=283, Evalue=7e-78,
Organism=Escherichia coli, GI48994985, Length=237, Percent_Identity=33.3333333333333, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI87082439, Length=263, Percent_Identity=31.1787072243346, Blast_Score=117, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17559024, Length=267, Percent_Identity=29.2134831460674, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71980746, Length=269, Percent_Identity=29.368029739777, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17543026, Length=292, Percent_Identity=27.0547945205479, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17565396, Length=147, Percent_Identity=32.6530612244898, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24586117, Length=290, Percent_Identity=28.6206896551724, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI221330018, Length=290, Percent_Identity=28.6206896551724, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24648690, Length=288, Percent_Identity=27.0833333333333, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29978; Mature: 29978

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIAVLIDSHCHLDRLKAAPDQQTLELILANAKARGVDYMLCVNVRQQGFESMRDKVAAF
CEEEEEECCCCCHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHH
EQVFLSSGVHPLDVKDGLDVEQIRRFAMDPKVVAIGETGLDYFYADETKALQQQCFEQQI
HHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCEEECCHHHHHHHHHHHHHH
ALAVEVNKPLIVHTRDAREDTINMLKAGQADKVGGVLHCFTENWEMAKAAIDLGFYISVS
EEEEECCCCEEEEECCCHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHCEEEEEE
GIVTFKNAGELRTVIRKVPKERLLVETDSPYLAPIPHRGQENQPAYVRDVAEFVAELRGE
EEEEECCCHHHHHHHHHCCHHHEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHCCH
RYEELAEYTSENFFNLFKDAARLIGR
HHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEIAVLIDSHCHLDRLKAAPDQQTLELILANAKARGVDYMLCVNVRQQGFESMRDKVAAF
CEEEEEECCCCCHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHH
EQVFLSSGVHPLDVKDGLDVEQIRRFAMDPKVVAIGETGLDYFYADETKALQQQCFEQQI
HHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCEEECCHHHHHHHHHHHHHH
ALAVEVNKPLIVHTRDAREDTINMLKAGQADKVGGVLHCFTENWEMAKAAIDLGFYISVS
EEEEECCCCEEEEECCCHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHCEEEEEE
GIVTFKNAGELRTVIRKVPKERLLVETDSPYLAPIPHRGQENQPAYVRDVAEFVAELRGE
EEEEECCCHHHHHHHHHCCHHHEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHCCH
RYEELAEYTSENFFNLFKDAARLIGR
HHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]