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The map label for this gene is gltT [H]

Identifier: 117920173

GI number: 117920173

Start: 2028777

End: 2030090

Strand: Reverse

Name: gltT [H]

Synonym: Shewana3_1726

Alternate gene names: 117920173

Gene position: 2030090-2028777 (Counterclockwise)

Preceding gene: 117920175

Following gene: 117920172

Centisome position: 40.83

GC content: 45.05

Gene sequence:

>1314_bases
ATGGCAACCTTATTACAAAAGAAATTCGGCCTTACAAGCAAAATTCTGTTCGGTATGGCAACAGGTATTGCTTTAGGTCT
CATACTCCGCAACGTCTTTCCAGAAAGCGATATCGTAAAAGACTATATTACTGAAGGTTTCTTACATGTTATCGGCACTA
TCTTTATCTCAAGTTTGAAAATGCTAGTGGTTCCACTGGTATTTATTTCATTAGTTTGTGGCACTTGCTCACTGAGTGAA
CCTTCAAAATTAGGTCGTTTAGGCGGCAAAACATTAGCCTTTTATTTATTCACAACAGCGATTGCTTTAATTCTCGCCAT
TGTCAGCGCGGTATTAGTTCATCCAGGTAATGCTTCGCTCGCTTCCGAAAAAATGGAGTACACAGCCAAAGAAGCGCCTA
GTCTTTCGAGCGTCCTAATCAATATAGTGCCAACGAATCCGATGCAAGCCATGAGCGAAGGCAATATGCTGCAGATTATT
ATCTTTGCGGTGATTTTTGGCTTTGCGATTGCGCATATTGGCGAACGTGGGAAACGTGTTGCCGCGTTATTTGAAGATTT
AAATGAAGTGATCATGCGGGTCGTTACGCTGATCATGCAGCTTGCGCCTTACGGGGTGTTTGCACTGATGGCAAAACTGG
CTTTAACGCTAGGTTTGGGAACATTCGAAAGTGTGGTCAAGTATTTCTTTGTCGTGTTGGTGGTGTTACTCATCCACGCC
TTTATCGTCTACCCGACCCTGCTTAAGTTATTCTCAGGCTTAAATCCGCTGATCTTTATTCGTAAGATGCGTGATGTGCA
GTTGTTTGCCTTTTCAACCGCAAGCTCAAACGCCACCTTACCGATTACGATTGAGGCGTCTGAGCACAGACTCGGTGTTG
ATAATAAAATTGCCTCTTTCACCCTGCCATTAGGTGCCACCATTAACATGGATGGCACGGCGATTATGCAAGGTGTCGCT
ACTGTATTTATCGCCCAAGTCTTTGGTATTGAGTTAACCATTACCGATTATGCTGCCGTTGTTGTCACCGCGACCTTAGC
GTCAATCGGTACTGCTGGGGTTCCGGGCGTAGGCTTGATCATGTTAGCTATGGTGCTTAACCAAGTTGGTCTGCCCGTTG
AAGGTATTGCCCTCATTATCGGGGTTGACCGACTGCTGGATATGGTGCGCACCGCGGTTAACGTAACAGGCGATTGCGTC
GCGACTGTGGTGATTGCCAAATCTGAAGGCGAATTTAACGAAACCGTATTCAACAATACTCAAGCCGGTAAAGTCGCCAG
TAACTTCGATGAACAAGTGCATAAAGTAGAGTAA

Upstream 100 bases:

>100_bases
GCAGTCAGTTTAACATCGGAACTCATTTAAACTTCTGCATTTTCTTGCTAGGCTTGTCGTCGCCAATATTAGAATGTATA
AAAAACACACAGGAATCCCC

Downstream 100 bases:

>100_bases
TCCTCACTTTCGAATGCATCTATATCTACTAAAAAGCCCAACTCAGTTGGGCTTTTTTATTTGTCTTATCCTAATTTTGT
GAACAAGCAAATAGAATAGT

Product: sodium:dicarboxylate symporter

Products: L-aspartate [Cytoplasm]; Proton [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate-aspartate carrier protein [H]

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MATLLQKKFGLTSKILFGMATGIALGLILRNVFPESDIVKDYITEGFLHVIGTIFISSLKMLVVPLVFISLVCGTCSLSE
PSKLGRLGGKTLAFYLFTTAIALILAIVSAVLVHPGNASLASEKMEYTAKEAPSLSSVLINIVPTNPMQAMSEGNMLQII
IFAVIFGFAIAHIGERGKRVAALFEDLNEVIMRVVTLIMQLAPYGVFALMAKLALTLGLGTFESVVKYFFVVLVVLLIHA
FIVYPTLLKLFSGLNPLIFIRKMRDVQLFAFSTASSNATLPITIEASEHRLGVDNKIASFTLPLGATINMDGTAIMQGVA
TVFIAQVFGIELTITDYAAVVVTATLASIGTAGVPGVGLIMLAMVLNQVGLPVEGIALIIGVDRLLDMVRTAVNVTGDCV
ATVVIAKSEGEFNETVFNNTQAGKVASNFDEQVHKVE

Sequences:

>Translated_437_residues
MATLLQKKFGLTSKILFGMATGIALGLILRNVFPESDIVKDYITEGFLHVIGTIFISSLKMLVVPLVFISLVCGTCSLSE
PSKLGRLGGKTLAFYLFTTAIALILAIVSAVLVHPGNASLASEKMEYTAKEAPSLSSVLINIVPTNPMQAMSEGNMLQII
IFAVIFGFAIAHIGERGKRVAALFEDLNEVIMRVVTLIMQLAPYGVFALMAKLALTLGLGTFESVVKYFFVVLVVLLIHA
FIVYPTLLKLFSGLNPLIFIRKMRDVQLFAFSTASSNATLPITIEASEHRLGVDNKIASFTLPLGATINMDGTAIMQGVA
TVFIAQVFGIELTITDYAAVVVTATLASIGTAGVPGVGLIMLAMVLNQVGLPVEGIALIIGVDRLLDMVRTAVNVTGDCV
ATVVIAKSEGEFNETVFNNTQAGKVASNFDEQVHKVE
>Mature_436_residues
ATLLQKKFGLTSKILFGMATGIALGLILRNVFPESDIVKDYITEGFLHVIGTIFISSLKMLVVPLVFISLVCGTCSLSEP
SKLGRLGGKTLAFYLFTTAIALILAIVSAVLVHPGNASLASEKMEYTAKEAPSLSSVLINIVPTNPMQAMSEGNMLQIII
FAVIFGFAIAHIGERGKRVAALFEDLNEVIMRVVTLIMQLAPYGVFALMAKLALTLGLGTFESVVKYFFVVLVVLLIHAF
IVYPTLLKLFSGLNPLIFIRKMRDVQLFAFSTASSNATLPITIEASEHRLGVDNKIASFTLPLGATINMDGTAIMQGVAT
VFIAQVFGIELTITDYAAVVVTATLASIGTAGVPGVGLIMLAMVLNQVGLPVEGIALIIGVDRLLDMVRTAVNVTGDCVA
TVVIAKSEGEFNETVFNNTQAGKVASNFDEQVHKVE

Specific function: This carrier protein is part of the Na(+)-dependent, binding-protein-independent glutamate-aspartate transport system [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI169790839, Length=413, Percent_Identity=35.1089588377724, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI40254478, Length=492, Percent_Identity=31.0975609756098, Blast_Score=198, Evalue=1e-50,
Organism=Homo sapiens, GI4827012, Length=294, Percent_Identity=40.4761904761905, Blast_Score=192, Evalue=8e-49,
Organism=Homo sapiens, GI21314632, Length=449, Percent_Identity=31.8485523385301, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI66773030, Length=404, Percent_Identity=33.6633663366337, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI5032093, Length=371, Percent_Identity=37.7358490566038, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI194239697, Length=259, Percent_Identity=39.3822393822394, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI223468566, Length=255, Percent_Identity=39.6078431372549, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI223468564, Length=246, Percent_Identity=39.8373983739837, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI262359914, Length=341, Percent_Identity=33.1378299120235, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI301601644, Length=164, Percent_Identity=41.4634146341463, Blast_Score=118, Evalue=1e-26,
Organism=Escherichia coli, GI1790514, Length=439, Percent_Identity=36.2186788154898, Blast_Score=253, Evalue=1e-68,
Organism=Escherichia coli, GI1789947, Length=425, Percent_Identity=30.8235294117647, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1788024, Length=455, Percent_Identity=30.989010989011, Blast_Score=168, Evalue=6e-43,
Organism=Escherichia coli, GI1789473, Length=376, Percent_Identity=28.1914893617021, Blast_Score=121, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71983099, Length=434, Percent_Identity=33.1797235023041, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI71983106, Length=434, Percent_Identity=33.1797235023041, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI17537407, Length=466, Percent_Identity=34.549356223176, Blast_Score=228, Evalue=4e-60,
Organism=Caenorhabditis elegans, GI193206505, Length=431, Percent_Identity=34.5707656612529, Blast_Score=220, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI71996953, Length=461, Percent_Identity=32.7548806941432, Blast_Score=214, Evalue=6e-56,
Organism=Caenorhabditis elegans, GI193206654, Length=432, Percent_Identity=31.4814814814815, Blast_Score=195, Evalue=5e-50,
Organism=Caenorhabditis elegans, GI17541374, Length=392, Percent_Identity=32.1428571428571, Blast_Score=181, Evalue=8e-46,
Organism=Drosophila melanogaster, GI24583025, Length=435, Percent_Identity=32.4137931034483, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI17137668, Length=435, Percent_Identity=32.4137931034483, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24583023, Length=435, Percent_Identity=32.4137931034483, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI281360481, Length=452, Percent_Identity=31.1946902654867, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI281360483, Length=452, Percent_Identity=31.1946902654867, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI17137666, Length=452, Percent_Identity=31.1946902654867, Blast_Score=152, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR018107 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 46637; Mature: 46506

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLLQKKFGLTSKILFGMATGIALGLILRNVFPESDIVKDYITEGFLHVIGTIFISSLK
CCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MLVVPLVFISLVCGTCSLSEPSKLGRLGGKTLAFYLFTTAIALILAIVSAVLVHPGNASL
HHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
ASEKMEYTAKEAPSLSSVLINIVPTNPMQAMSEGNMLQIIIFAVIFGFAIAHIGERGKRV
HHHHHHHHHHCCCCHHHHHEEEECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AALFEDLNEVIMRVVTLIMQLAPYGVFALMAKLALTLGLGTFESVVKYFFVVLVVLLIHA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
FIVYPTLLKLFSGLNPLIFIRKMRDVQLFAFSTASSNATLPITIEASEHRLGVDNKIASF
HHHHHHHHHHHCCCCHHHHHHHHCCEEEEEEEECCCCCEEEEEEECCCCCCCCCCCHHEE
TLPLGATINMDGTAIMQGVATVFIAQVFGIELTITDYAAVVVTATLASIGTAGVPGVGLI
EECCCCEECCCHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHCCCCCCHHHHH
MLAMVLNQVGLPVEGIALIIGVDRLLDMVRTAVNVTGDCVATVVIAKSEGEFNETVFNNT
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEECCCCCCHHHHHCCC
QAGKVASNFDEQVHKVE
CCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATLLQKKFGLTSKILFGMATGIALGLILRNVFPESDIVKDYITEGFLHVIGTIFISSLK
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MLVVPLVFISLVCGTCSLSEPSKLGRLGGKTLAFYLFTTAIALILAIVSAVLVHPGNASL
HHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
ASEKMEYTAKEAPSLSSVLINIVPTNPMQAMSEGNMLQIIIFAVIFGFAIAHIGERGKRV
HHHHHHHHHHCCCCHHHHHEEEECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AALFEDLNEVIMRVVTLIMQLAPYGVFALMAKLALTLGLGTFESVVKYFFVVLVVLLIHA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
FIVYPTLLKLFSGLNPLIFIRKMRDVQLFAFSTASSNATLPITIEASEHRLGVDNKIASF
HHHHHHHHHHHCCCCHHHHHHHHCCEEEEEEEECCCCCEEEEEEECCCCCCCCCCCHHEE
TLPLGATINMDGTAIMQGVATVFIAQVFGIELTITDYAAVVVTATLASIGTAGVPGVGLI
EECCCCEECCCHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHCCCCCCHHHHH
MLAMVLNQVGLPVEGIALIIGVDRLLDMVRTAVNVTGDCVATVVIAKSEGEFNETVFNNT
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEECCCCCCHHHHHCCC
QAGKVASNFDEQVHKVE
CCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate [Periplasm]; Proton [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-aspartate [Periplasm] = Proton [Cytoplasm] + L-aspartate [Cytoplasm] Proton [Periplasm] + L-glutamate [Periplasm] = Proton [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]