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The map label for this gene is sdhB [H]

Identifier: 117920156

GI number: 117920156

Start: 2011730

End: 2012437

Strand: Direct

Name: sdhB [H]

Synonym: Shewana3_1709

Alternate gene names: 117920156

Gene position: 2011730-2012437 (Clockwise)

Preceding gene: 117920155

Following gene: 117920157

Centisome position: 40.46

GC content: 46.61

Gene sequence:

>708_bases
ATGAAATTGGAATTTGCAGTTTATCGTTACAATCCTGATGTAGATACAAAACCTTACATGCAGGATTACAGCCTCGAAGT
GGCTGAAGGCTCTGACATGATGGTGCTTGATGCACTGATCAAGTTAAAAGAACAGGACCCAACGTTAGCGTTCCGTCGCT
CATGCCGTGAAGGTGTTTGCGGTAGTGACGGTGTGAACATGAACGGTAAAAACGGTCTGGCTTGTATTACGCCAATCTCT
ACCTTCAAAGGTAAGAAGTTGGAAATTCGTCCACTGCCAGGTATGCCAGTCGTACGTGACTTAGTGGTTGATTTAACTCA
GTTCTACAAGCAGTACGAGAAGATCAAGCCGTTCCTCATCAACGATGAGAAGATGCCTGCTCGTGAACATTTACAGTCAC
CTGAACAGCGTGCGCATTTAGATGGTCTGTACGAATGTATCATGTGTGCATGTTGTTCTACGGCTTGTCCATCGTTCTGG
TGGAATCCTGATAAGTTTATCGGTCCTAGCGGTCTGCTACACGCTTACCGTTTCTTGATCGACAGCCGCGATACAGCGAC
AGAAGAACGTCTTTCTGAGCTGGACGACGCCTACAGCGTGTTCCGTTGCCACGGCATCATGAACTGCGTTGACGTCTGTC
CAAAAGGACTTAATCCGACTAAAGCAATTGGTCACATTAAGTCAATGCTGCTTAAGCGAGCTGTGTAA

Upstream 100 bases:

>100_bases
ACCCTGTGACTGAAACCATGGACCGTCGTGCTGTGAATATGGCGCCTAAGTTACGTGAAGCATTCCCGCCGAAGAAACGT
ACCTACTAGGAGTTGCAAAG

Downstream 100 bases:

>100_bases
TGCGAGAACCCGAGCTTAAATCAATAATAATATAGCTCTCGAAGAGTCACTTTCTGGGTATAGAAGGTGGCTCTTTTGTG
TATGTAATGGAAGACAACGC

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MKLEFAVYRYNPDVDTKPYMQDYSLEVAEGSDMMVLDALIKLKEQDPTLAFRRSCREGVCGSDGVNMNGKNGLACITPIS
TFKGKKLEIRPLPGMPVVRDLVVDLTQFYKQYEKIKPFLINDEKMPAREHLQSPEQRAHLDGLYECIMCACCSTACPSFW
WNPDKFIGPSGLLHAYRFLIDSRDTATEERLSELDDAYSVFRCHGIMNCVDVCPKGLNPTKAIGHIKSMLLKRAV

Sequences:

>Translated_235_residues
MKLEFAVYRYNPDVDTKPYMQDYSLEVAEGSDMMVLDALIKLKEQDPTLAFRRSCREGVCGSDGVNMNGKNGLACITPIS
TFKGKKLEIRPLPGMPVVRDLVVDLTQFYKQYEKIKPFLINDEKMPAREHLQSPEQRAHLDGLYECIMCACCSTACPSFW
WNPDKFIGPSGLLHAYRFLIDSRDTATEERLSELDDAYSVFRCHGIMNCVDVCPKGLNPTKAIGHIKSMLLKRAV
>Mature_235_residues
MKLEFAVYRYNPDVDTKPYMQDYSLEVAEGSDMMVLDALIKLKEQDPTLAFRRSCREGVCGSDGVNMNGKNGLACITPIS
TFKGKKLEIRPLPGMPVVRDLVVDLTQFYKQYEKIKPFLINDEKMPAREHLQSPEQRAHLDGLYECIMCACCSTACPSFW
WNPDKFIGPSGLLHAYRFLIDSRDTATEERLSELDDAYSVFRCHGIMNCVDVCPKGLNPTKAIGHIKSMLLKRAV

Specific function: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth [H]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=231, Percent_Identity=56.7099567099567, Blast_Score=267, Evalue=7e-72,
Organism=Escherichia coli, GI1786943, Length=236, Percent_Identity=77.5423728813559, Blast_Score=394, Evalue=1e-111,
Organism=Escherichia coli, GI1790596, Length=228, Percent_Identity=37.719298245614, Blast_Score=153, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17533915, Length=232, Percent_Identity=52.5862068965517, Blast_Score=252, Evalue=1e-67,
Organism=Saccharomyces cerevisiae, GI6322987, Length=230, Percent_Identity=55.2173913043478, Blast_Score=258, Evalue=8e-70,
Organism=Drosophila melanogaster, GI17137106, Length=233, Percent_Identity=56.2231759656652, Blast_Score=273, Evalue=6e-74,
Organism=Drosophila melanogaster, GI24643156, Length=231, Percent_Identity=51.9480519480519, Blast_Score=250, Evalue=4e-67,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 26612; Mature: 26612

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
8.9 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
8.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLEFAVYRYNPDVDTKPYMQDYSLEVAEGSDMMVLDALIKLKEQDPTLAFRRSCREGVC
CCCEEEEEEECCCCCCCCCHHHCEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCC
GSDGVNMNGKNGLACITPISTFKGKKLEIRPLPGMPVVRDLVVDLTQFYKQYEKIKPFLI
CCCCCCCCCCCCEEEECCHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEE
NDEKMPAREHLQSPEQRAHLDGLYECIMCACCSTACPSFWWNPDKFIGPSGLLHAYRFLI
CCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
DSRDTATEERLSELDDAYSVFRCHGIMNCVDVCPKGLNPTKAIGHIKSMLLKRAV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLEFAVYRYNPDVDTKPYMQDYSLEVAEGSDMMVLDALIKLKEQDPTLAFRRSCREGVC
CCCEEEEEEECCCCCCCCCHHHCEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCC
GSDGVNMNGKNGLACITPISTFKGKKLEIRPLPGMPVVRDLVVDLTQFYKQYEKIKPFLI
CCCCCCCCCCCCEEEECCHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEE
NDEKMPAREHLQSPEQRAHLDGLYECIMCACCSTACPSFWWNPDKFIGPSGLLHAYRFLI
CCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
DSRDTATEERLSELDDAYSVFRCHGIMNCVDVCPKGLNPTKAIGHIKSMLLKRAV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6388571; 8905232; 9278503; 6376123; 9298646 [H]