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The map label for this gene is nhaB [H]

Identifier: 117920081

GI number: 117920081

Start: 1922960

End: 1924561

Strand: Reverse

Name: nhaB [H]

Synonym: Shewana3_1634

Alternate gene names: 117920081

Gene position: 1924561-1922960 (Counterclockwise)

Preceding gene: 117920083

Following gene: 117920080

Centisome position: 38.71

GC content: 47.13

Gene sequence:

>1602_bases
ATGCCGATGACAATGAGTCAGGCGTTTATTGGGAACTTCTTAGGGAATTCTCCTAAGTGGTACAAGATCGCAATACTGTC
GTTTTTAATAATCAATCCAATACTCTTTTTCTATGTCAGCCCCTTTGTGGCTGGTTGGGTATTAGTACTTGAGTTTATTT
TTACCTTGGCAATGGCGCTAAAATGCTACCCATTACAACCCGGTGGTCTATTAGCGATTGAAGCTGTCGCCATCGGCATG
ACCTCAGCAAGCCAAGTGCTGCACGAAATTGAAGCGAACCTTGAAGTGCTATTACTGCTGGTATTTATGGTGGCCGGCAT
TTACTTCATGAAGCAGCTACTGCTGTTTGTGTTCACTAAGATGATCACTAAAGTACGTTCGAAAATCTTAGTGTCTTTGT
TGTTCTGTCTAGCTTCCGCCTTCTTATCCGCCTTCTTAGATGCGTTAACTGTTATCGCCGTGATTATCACCGTGGCGGTT
GGTTTTTACTCCATCTATCACAAAGTCGCCTCAGGTAAAGATTTCTCGGCCGATCATGACCATACCTCCGAAGGCAAAAA
TGACGATGGTGAAAATCAGCTCAACGAAGACGAGCTGGAATCCTTCCGTGGTTTCCTACGTAACCTGTTAATGCACGCCG
GTGTCGGTACTGCATTGGGTGGCGTGTGTACTATGGTGGGTGAACCGCAAAACTTAATTATTGCAGCTCAAGCAAACTGG
CAATTTGGCGAATTTGCGATCCGTATGTCACCTGTGACAGTGCCTGTATTGTTCGCAGGTATCCTCACCTGCTTTATCGT
CGAGAAATTCCGTTGGTTTGGTTATGGTGCCCAGCTTCCGGATGCGGTGCATAAAATCCTATGTGATTACGCCGCCTATG
AAGACGCACGTCGTACCAACAAAGACAAGATGAAGCTGGTTATCCAAGCCTTTGTGGGTGTGTGGTTGATTGCGGGTCTC
GCGCTGCACTTAGCGTCTGTGGGCTTGATTGGTCTGTCTGTGATCATCTTAACCACGGCCTTTAACGGTATTACCGATGA
GCATGCGCTAGGTAAAGCCTTCGAAGAAGCCCTGCCCTTTACGGCCTTGTTAGCGGTGTTCTTTGCGGTTGTTGCCGTAA
TCATCGACCAACAACTGTTTGGCCCTGTCATCCAATGGGCACTAAACCATGAAGGTAATACCCAATTAGTGATCTTCTAT
ATCGCTAACGGTTTACTCTCTATGGTCAGTGATAACGTGTTTGTGGGCACGGTTTACATTAACGAGGTCAAAGCCGCCCT
GATTAACGGTCAAATCACCCGGGATCAATTCGACCTGTTAGCAGTTGCGATTAACACTGGTACTAACTTGCCTTCGGTGG
CAACACCAAACGGTCAAGCCGCATTCCTGTTCTTATTGACCTCGGCTCTTGCACCGCTGATCCGTTTATCCTACGGCAGA
ATGGTTTGGATGGCATTGCCCTACACTATCGTGCTATCGATTGTGGGCGTGATGGCTATTCAATCGGGCTTCTTAGAGCA
GATGACCCAGTACTTCTATGACTCCCATGCAATATTGCACCACAGTGTTAAAGAAGCGTTAGCGCCTGCTGCAGCTCACT
AA

Upstream 100 bases:

>100_bases
GTTACATTAGCATTCTCTTTAGGCTAGACTGATTTTCTAAAACAAATGCCAGAAACAATAACCTGTGCAATTTTAAAAGA
TAATTAGAAGAGAGGATGCC

Downstream 100 bases:

>100_bases
CATAAATATCGGAGTTGACTGAACTTTATGAGTTCAGTAAAGTCAAAAAAACGCCCTACCTTCGAGGGCGTTTTTTGTTG
ATACGGAGTTCACTTTTGAC

Product: sodium/proton antiporter

Products: Na (I) [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: Sodium/proton antiporter nhaB [H]

Number of amino acids: Translated: 533; Mature: 532

Protein sequence:

>533_residues
MPMTMSQAFIGNFLGNSPKWYKIAILSFLIINPILFFYVSPFVAGWVLVLEFIFTLAMALKCYPLQPGGLLAIEAVAIGM
TSASQVLHEIEANLEVLLLLVFMVAGIYFMKQLLLFVFTKMITKVRSKILVSLLFCLASAFLSAFLDALTVIAVIITVAV
GFYSIYHKVASGKDFSADHDHTSEGKNDDGENQLNEDELESFRGFLRNLLMHAGVGTALGGVCTMVGEPQNLIIAAQANW
QFGEFAIRMSPVTVPVLFAGILTCFIVEKFRWFGYGAQLPDAVHKILCDYAAYEDARRTNKDKMKLVIQAFVGVWLIAGL
ALHLASVGLIGLSVIILTTAFNGITDEHALGKAFEEALPFTALLAVFFAVVAVIIDQQLFGPVIQWALNHEGNTQLVIFY
IANGLLSMVSDNVFVGTVYINEVKAALINGQITRDQFDLLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGR
MVWMALPYTIVLSIVGVMAIQSGFLEQMTQYFYDSHAILHHSVKEALAPAAAH

Sequences:

>Translated_533_residues
MPMTMSQAFIGNFLGNSPKWYKIAILSFLIINPILFFYVSPFVAGWVLVLEFIFTLAMALKCYPLQPGGLLAIEAVAIGM
TSASQVLHEIEANLEVLLLLVFMVAGIYFMKQLLLFVFTKMITKVRSKILVSLLFCLASAFLSAFLDALTVIAVIITVAV
GFYSIYHKVASGKDFSADHDHTSEGKNDDGENQLNEDELESFRGFLRNLLMHAGVGTALGGVCTMVGEPQNLIIAAQANW
QFGEFAIRMSPVTVPVLFAGILTCFIVEKFRWFGYGAQLPDAVHKILCDYAAYEDARRTNKDKMKLVIQAFVGVWLIAGL
ALHLASVGLIGLSVIILTTAFNGITDEHALGKAFEEALPFTALLAVFFAVVAVIIDQQLFGPVIQWALNHEGNTQLVIFY
IANGLLSMVSDNVFVGTVYINEVKAALINGQITRDQFDLLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGR
MVWMALPYTIVLSIVGVMAIQSGFLEQMTQYFYDSHAILHHSVKEALAPAAAH
>Mature_532_residues
PMTMSQAFIGNFLGNSPKWYKIAILSFLIINPILFFYVSPFVAGWVLVLEFIFTLAMALKCYPLQPGGLLAIEAVAIGMT
SASQVLHEIEANLEVLLLLVFMVAGIYFMKQLLLFVFTKMITKVRSKILVSLLFCLASAFLSAFLDALTVIAVIITVAVG
FYSIYHKVASGKDFSADHDHTSEGKNDDGENQLNEDELESFRGFLRNLLMHAGVGTALGGVCTMVGEPQNLIIAAQANWQ
FGEFAIRMSPVTVPVLFAGILTCFIVEKFRWFGYGAQLPDAVHKILCDYAAYEDARRTNKDKMKLVIQAFVGVWLIAGLA
LHLASVGLIGLSVIILTTAFNGITDEHALGKAFEEALPFTALLAVFFAVVAVIIDQQLFGPVIQWALNHEGNTQLVIFYI
ANGLLSMVSDNVFVGTVYINEVKAALINGQITRDQFDLLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRM
VWMALPYTIVLSIVGVMAIQSGFLEQMTQYFYDSHAILHHSVKEALAPAAAH

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG3067

COG function: function code P; Na+/H+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nhaB Na(+)/H(+) (TC 2.A.34) antiporter family [H]

Homologues:

Organism=Escherichia coli, GI1787435, Length=488, Percent_Identity=68.2377049180328, Blast_Score=660, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004671 [H]

Pfam domain/function: PF06450 NhaB [H]

EC number: NA

Molecular weight: Translated: 58228; Mature: 58097

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMTMSQAFIGNFLGNSPKWYKIAILSFLIINPILFFYVSPFVAGWVLVLEFIFTLAMAL
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KCYPLQPGGLLAIEAVAIGMTSASQVLHEIEANLEVLLLLVFMVAGIYFMKQLLLFVFTK
HCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MITKVRSKILVSLLFCLASAFLSAFLDALTVIAVIITVAVGFYSIYHKVASGKDFSADHD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
HTSEGKNDDGENQLNEDELESFRGFLRNLLMHAGVGTALGGVCTMVGEPQNLIIAAQANW
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCC
QFGEFAIRMSPVTVPVLFAGILTCFIVEKFRWFGYGAQLPDAVHKILCDYAAYEDARRTN
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC
KDKMKLVIQAFVGVWLIAGLALHLASVGLIGLSVIILTTAFNGITDEHALGKAFEEALPF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCH
TALLAVFFAVVAVIIDQQLFGPVIQWALNHEGNTQLVIFYIANGLLSMVSDNVFVGTVYI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHCCCEEEEEEEH
NEVKAALINGQITRDQFDLLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGR
HHHHHHHHCCCCCHHHHHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
MVWMALPYTIVLSIVGVMAIQSGFLEQMTQYFYDSHAILHHSVKEALAPAAAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PMTMSQAFIGNFLGNSPKWYKIAILSFLIINPILFFYVSPFVAGWVLVLEFIFTLAMAL
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KCYPLQPGGLLAIEAVAIGMTSASQVLHEIEANLEVLLLLVFMVAGIYFMKQLLLFVFTK
HCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MITKVRSKILVSLLFCLASAFLSAFLDALTVIAVIITVAVGFYSIYHKVASGKDFSADHD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
HTSEGKNDDGENQLNEDELESFRGFLRNLLMHAGVGTALGGVCTMVGEPQNLIIAAQANW
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCC
QFGEFAIRMSPVTVPVLFAGILTCFIVEKFRWFGYGAQLPDAVHKILCDYAAYEDARRTN
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC
KDKMKLVIQAFVGVWLIAGLALHLASVGLIGLSVIILTTAFNGITDEHALGKAFEEALPF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCH
TALLAVFFAVVAVIIDQQLFGPVIQWALNHEGNTQLVIFYIANGLLSMVSDNVFVGTVYI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHCCCEEEEEEEH
NEVKAALINGQITRDQFDLLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGR
HHHHHHHHCCCCCHHHHHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
MVWMALPYTIVLSIVGVMAIQSGFLEQMTQYFYDSHAILHHSVKEALAPAAAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3 Proton [Periplasm]; Na (I) [Cytoplasm] [C]

Specific reaction: 3 Proton [Periplasm] + 2 Na (I) [Cytoplasm] = 2 Na (I) [Periplasm] + 3 Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA