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The map label for this gene is trpG [H]

Identifier: 117919967

GI number: 117919967

Start: 1769700

End: 1770308

Strand: Reverse

Name: trpG [H]

Synonym: Shewana3_1519

Alternate gene names: 117919967

Gene position: 1770308-1769700 (Counterclockwise)

Preceding gene: 117919968

Following gene: 117919966

Centisome position: 35.6

GC content: 51.07

Gene sequence:

>609_bases
ATGAAACTCTATTTACTCGATAACTTCGACTCCTTTACCTACAACTTAGTCGACCAATTTAGAAGCCTTGGCTGTGAAGT
GGTGATCTACCGTAACGATGTTGCCGCCGACTATATTGCCAACAAGCTGTTAGCGGAAACAGAGCCCAGCGCCTTAGTCC
TATCGCCAGGCCCAGGTGCGCCCCATGAAGCGGGCTCCATGATGTCGCTGATCGACAAAGTCGCGGGCAAAGTGCCTATG
CTTGGGATCTGCTTAGGCCATCAAGCCATGGTGGAATATTACGGTGGTAAAGTGGAGCGCGCGCCTTTTGTGGTGCACGG
TAAAGCCAGCCCCACCTTCCATAATGGTACAGGTGTGTTTGCTAACTTGCCTTCGCCCTTACCTGTCGCCCGTTATCACA
GCTTAGTCGCCACAAAAGTCCCCGATTGTCTTGAAGTGATTGCCACCACAGAAGAGATGCCAATGGCGATTTTGCATGCC
GAGCACAGGGCGGTCGGTTTTCAGTTTCACCCAGAATCCATCTTAACCACCTTGGGCAGCACATTGTTAACCCAAACCTT
ACGCTTTTTGACTCAAGACATCGTCCACAATACCGCAGGAGCCCAATAA

Upstream 100 bases:

>100_bases
CAGGCTGTGATTTCGGCCATCAAGATGGGCGCAGGCTTGGATGAAAGCCAGCAAGCAACTGCGACCACTACGACTGAACA
ACAAAGATAAGGAGCCCAAG

Downstream 100 bases:

>100_bases
TGAGCGCAACATCGATTCAGCCCCTGCTCGATATCTTGTTTCTGGGTAAAGCATTAACCCGCGAGCAAACCGCCAGCCTC
TTTAGCACCCTTATCCAAGG

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MKLYLLDNFDSFTYNLVDQFRSLGCEVVIYRNDVAADYIANKLLAETEPSALVLSPGPGAPHEAGSMMSLIDKVAGKVPM
LGICLGHQAMVEYYGGKVERAPFVVHGKASPTFHNGTGVFANLPSPLPVARYHSLVATKVPDCLEVIATTEEMPMAILHA
EHRAVGFQFHPESILTTLGSTLLTQTLRFLTQDIVHNTAGAQ

Sequences:

>Translated_202_residues
MKLYLLDNFDSFTYNLVDQFRSLGCEVVIYRNDVAADYIANKLLAETEPSALVLSPGPGAPHEAGSMMSLIDKVAGKVPM
LGICLGHQAMVEYYGGKVERAPFVVHGKASPTFHNGTGVFANLPSPLPVARYHSLVATKVPDCLEVIATTEEMPMAILHA
EHRAVGFQFHPESILTTLGSTLLTQTLRFLTQDIVHNTAGAQ
>Mature_202_residues
MKLYLLDNFDSFTYNLVDQFRSLGCEVVIYRNDVAADYIANKLLAETEPSALVLSPGPGAPHEAGSMMSLIDKVAGKVPM
LGICLGHQAMVEYYGGKVERAPFVVHGKASPTFHNGTGVFANLPSPLPVARYHSLVATKVPDCLEVIATTEEMPMAILHA
EHRAVGFQFHPESILTTLGSTLLTQTLRFLTQDIVHNTAGAQ

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=192, Percent_Identity=54.1666666666667, Blast_Score=205, Evalue=1e-54,
Organism=Escherichia coli, GI1789760, Length=190, Percent_Identity=48.4210526315789, Blast_Score=168, Evalue=3e-43,
Organism=Escherichia coli, GI1788854, Length=200, Percent_Identity=27.5, Blast_Score=68, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6322638, Length=187, Percent_Identity=41.7112299465241, Blast_Score=151, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6324361, Length=140, Percent_Identity=32.8571428571429, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 21896; Mature: 21896

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYLLDNFDSFTYNLVDQFRSLGCEVVIYRNDVAADYIANKLLAETEPSALVLSPGPGA
CEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCC
PHEAGSMMSLIDKVAGKVPMLGICLGHQAMVEYYGGKVERAPFVVHGKASPTFHNGTGVF
CCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCCCCCEEEECCCCCCEECCCEEE
ANLPSPLPVARYHSLVATKVPDCLEVIATTEEMPMAILHAEHRAVGFQFHPESILTTLGS
EECCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHCCEEECHHHHHHHHHH
TLLTQTLRFLTQDIVHNTAGAQ
HHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKLYLLDNFDSFTYNLVDQFRSLGCEVVIYRNDVAADYIANKLLAETEPSALVLSPGPGA
CEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCC
PHEAGSMMSLIDKVAGKVPMLGICLGHQAMVEYYGGKVERAPFVVHGKASPTFHNGTGVF
CCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCCCCCEEEECCCCCCEECCCEEE
ANLPSPLPVARYHSLVATKVPDCLEVIATTEEMPMAILHAEHRAVGFQFHPESILTTLGS
EECCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHCCEEECHHHHHHHHHH
TLLTQTLRFLTQDIVHNTAGAQ
HHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1773058; 12620739 [H]