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The map label for this gene is trpD [H]

Identifier: 117919966

GI number: 117919966

Start: 1768657

End: 1769700

Strand: Reverse

Name: trpD [H]

Synonym: Shewana3_1518

Alternate gene names: 117919966

Gene position: 1769700-1768657 (Counterclockwise)

Preceding gene: 117919967

Following gene: 117919965

Centisome position: 35.59

GC content: 53.16

Gene sequence:

>1044_bases
ATGAGCGCAACATCGATTCAGCCCCTGCTCGATATCTTGTTTCTGGGTAAAGCATTAACCCGCGAGCAAACCGCCAGCCT
CTTTAGCACCCTTATCCAAGGTGAAATGAATGAGGCCGTGATGGCGGCAATGTTAATGGCCCTTAAAATTCGCGGCGAAA
CCATTGCCGAAATCAGTGGCGCCGCCGATGCGATGCGCGCCGCCGCCAAGCCATTCCCCTATCCAGCCTCAAGCCGTAGC
CAAGGGATTATCGATATCGTCGGCACAGGTGGTGATGGTTTTAATACCATCAATATCTCCACCACAGCAGCCTTTGTCGC
GGCAGCCGCTGGCGCCAAGGTCGCAAAACACGGTAATCGCTCGGTCTCGAGCAAATCGGGCTCTTCGGATTTACTCGCCC
AATTTGGCATCGATTTAACCATGTCACCCGAGCTGGCGAGCCGTTGCCTGGAATCACTCAATCTGTGCTTCCTGTTTGCG
CCCCACTACCATGGCGGTGTCAAACATGCGGTGCCTGTTCGCCAAGCGCTGAAAACTCGCACCTTATTCAATGTGTTAGG
GCCATTGATTAACCCTGCGCGCCCAGAATTTATGTTGCTTGGGGTGTATAGCCCAGAGCTAGTGACGCCCATCGCCCGCG
TACTGCAAGCCCTTGGTACGCAAAGAGCCATGGTGGTACACGGCAGTGGTTTAGATGAAGTAGCGCTCCATGGCAGCACG
CAAGTCGCCGAACTTAAAGACGGTGAGATTATTGAATATCAACTAACGCCTGCGGATTTTGGCGTGCCACAAGCCCAAAT
TAGCGAGCTTGAAGGCGGAGAGCCCGCACAAAACGCCCAAATCACTCAATCTATTTTGCAAGGACAAGGCAGCGATGCCC
ACACCCATGCGGTTGCCATCAATGCAGGTTGTGCCTTATATCTGTGTGGCCTGTCGGACTCAGTCAAAGCTGGCACCGCC
CTTGCGCTCAATACCATAAAAAGCGGCAAAGCCTTTGAATTACTGAATCAACTCGCTAAAGTCAGCAGCGAAGCACAGGA
ATAA

Upstream 100 bases:

>100_bases
ACCCAGAATCCATCTTAACCACCTTGGGCAGCACATTGTTAACCCAAACCTTACGCTTTTTGACTCAAGACATCGTCCAC
AATACCGCAGGAGCCCAATA

Downstream 100 bases:

>100_bases
TGACCATGACACAGGTTCAACAACCCGACGCCCATCGCTCGGAAGATAATCAAGCATCGCAGGATGTAAGGGGTAGCATG
CAAACCAGCACCGCAAAAGC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSATSIQPLLDILFLGKALTREQTASLFSTLIQGEMNEAVMAAMLMALKIRGETIAEISGAADAMRAAAKPFPYPASSRS
QGIIDIVGTGGDGFNTINISTTAAFVAAAAGAKVAKHGNRSVSSKSGSSDLLAQFGIDLTMSPELASRCLESLNLCFLFA
PHYHGGVKHAVPVRQALKTRTLFNVLGPLINPARPEFMLLGVYSPELVTPIARVLQALGTQRAMVVHGSGLDEVALHGST
QVAELKDGEIIEYQLTPADFGVPQAQISELEGGEPAQNAQITQSILQGQGSDAHTHAVAINAGCALYLCGLSDSVKAGTA
LALNTIKSGKAFELLNQLAKVSSEAQE

Sequences:

>Translated_347_residues
MSATSIQPLLDILFLGKALTREQTASLFSTLIQGEMNEAVMAAMLMALKIRGETIAEISGAADAMRAAAKPFPYPASSRS
QGIIDIVGTGGDGFNTINISTTAAFVAAAAGAKVAKHGNRSVSSKSGSSDLLAQFGIDLTMSPELASRCLESLNLCFLFA
PHYHGGVKHAVPVRQALKTRTLFNVLGPLINPARPEFMLLGVYSPELVTPIARVLQALGTQRAMVVHGSGLDEVALHGST
QVAELKDGEIIEYQLTPADFGVPQAQISELEGGEPAQNAQITQSILQGQGSDAHTHAVAINAGCALYLCGLSDSVKAGTA
LALNTIKSGKAFELLNQLAKVSSEAQE
>Mature_346_residues
SATSIQPLLDILFLGKALTREQTASLFSTLIQGEMNEAVMAAMLMALKIRGETIAEISGAADAMRAAAKPFPYPASSRSQ
GIIDIVGTGGDGFNTINISTTAAFVAAAAGAKVAKHGNRSVSSKSGSSDLLAQFGIDLTMSPELASRCLESLNLCFLFAP
HYHGGVKHAVPVRQALKTRTLFNVLGPLINPARPEFMLLGVYSPELVTPIARVLQALGTQRAMVVHGSGLDEVALHGSTQ
VAELKDGEIIEYQLTPADFGVPQAQISELEGGEPAQNAQITQSILQGQGSDAHTHAVAINAGCALYLCGLSDSVKAGTAL
ALNTIKSGKAFELLNQLAKVSSEAQE

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=337, Percent_Identity=54.0059347181009, Blast_Score=318, Evalue=4e-88,
Organism=Saccharomyces cerevisiae, GI6320561, Length=360, Percent_Identity=31.6666666666667, Blast_Score=130, Evalue=3e-31,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 36225; Mature: 36094

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATSIQPLLDILFLGKALTREQTASLFSTLIQGEMNEAVMAAMLMALKIRGETIAEISG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHH
AADAMRAAAKPFPYPASSRSQGIIDIVGTGGDGFNTINISTTAAFVAAAAGAKVAKHGNR
HHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEHHHHHHHHHHHCHHHHHCCCC
SVSSKSGSSDLLAQFGIDLTMSPELASRCLESLNLCFLFAPHYHGGVKHAVPVRQALKTR
CCCCCCCCHHHHHHHCCCEEECHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHH
TLFNVLGPLINPARPEFMLLGVYSPELVTPIARVLQALGTQRAMVVHGSGLDEVALHGST
HHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHCCCCC
QVAELKDGEIIEYQLTPADFGVPQAQISELEGGEPAQNAQITQSILQGQGSDAHTHAVAI
EEEECCCCCEEEEEECCHHCCCCHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEE
NAGCALYLCGLSDSVKAGTALALNTIKSGKAFELLNQLAKVSSEAQE
ECCCEEEEECCCCCCCCCHHEEEHHHCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SATSIQPLLDILFLGKALTREQTASLFSTLIQGEMNEAVMAAMLMALKIRGETIAEISG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHH
AADAMRAAAKPFPYPASSRSQGIIDIVGTGGDGFNTINISTTAAFVAAAAGAKVAKHGNR
HHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEHHHHHHHHHHHCHHHHHCCCC
SVSSKSGSSDLLAQFGIDLTMSPELASRCLESLNLCFLFAPHYHGGVKHAVPVRQALKTR
CCCCCCCCHHHHHHHCCCEEECHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHH
TLFNVLGPLINPARPEFMLLGVYSPELVTPIARVLQALGTQRAMVVHGSGLDEVALHGST
HHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHCCCCC
QVAELKDGEIIEYQLTPADFGVPQAQISELEGGEPAQNAQITQSILQGQGSDAHTHAVAI
EEEECCCCCEEEEEECCHHCCCCHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEE
NAGCALYLCGLSDSVKAGTALALNTIKSGKAFELLNQLAKVSSEAQE
ECCCEEEEECCCCCCCCCHHEEEHHHCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]