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The map label for this gene is dctD [H]

Identifier: 117919860

GI number: 117919860

Start: 1635442

End: 1636821

Strand: Reverse

Name: dctD [H]

Synonym: Shewana3_1412

Alternate gene names: 117919860

Gene position: 1636821-1635442 (Counterclockwise)

Preceding gene: 117919861

Following gene: 117919857

Centisome position: 32.92

GC content: 50.0

Gene sequence:

>1380_bases
ATGAGTCTGCCCAATTCAATTCAAGACTATAGCGTACTGATCATCGACGATGAGCCCCATATTGGCACAGTGCTCGTACA
GCTTTTTGAGCTTGAAGGCATTAAAGCCTTCGCCACTACCGATCCCAAAGGGATTGCCAAATTACTCGACAGGGACTGGG
CGGGCGTGGTGATTTCCGATGTGAATATGCCGCAACTCGATGGCATCAGCCTGATGCAACAAATTCGTCAACAGGACCCC
GATTTACCCGTGGTGCTGCTCACAGGCTTTGGCGATATCGCCATGGCCGTCAATGCCTTAAAACAAGGTGCCTACGATTT
TCTCGAAAAACCCTTTAACAACGAACACATGTTAGATGTGGTGAAACGCGCCTTAGATAAACGCAGTCTCACCCTAGAGA
ACCGTAAATTAAAGAAAGAGTTAGAAAGCCATAACGTGCCCGGGCCAAGAATATTAGGCCACAGTGTCGGCATTTTGCGC
ATGCGTCATATCATAGACCAAGTAATCGATACCCCCGCCGATGTGCTTATCGAAGGTGAAACGGGTACGGGTAAGGAATT
GGTCGCCCGCTATCTACACGACCACAGCAGTCGCAATCAGGCCAACTTTGTCGCCATTAACTGCGGCGCGATTCCCGAAA
ACTTGATTGAGAGCGAACTCTTTGGCGCCGAAGCCGGAGCCTTTACCGGTGTCGATAAACTGCGTATCGGTAAGTTTGAG
TATGCCAACGGCGGCACACTCTTTTTAGATGAAATCGAAAGCACGCCACTGTCGTTACAGGTCAAACTGCTGCGGGTGCT
CGAAGATCGCAAGGTCGAGCGCTTAGGCTCCAATAAGAGCATTCATTTGGATATTCGAGTGATTGCCGCCACTAAGGTGG
ATTTAAAGTCCCTGTGCGACACCGGAGAGTTTCGCCAAGACTTGCTCTATCGCTTAAATCTGGTGACAGTGCCGATTCCA
CCACTCAGGGATCGCCGCGAAGATATTCCCTTATTATTCTTACATTTTGCCCGTATGGCTTCTGCACGTTACCACAAGGC
GCTGATTGCCCTCAATGCCGAGCAGAATGCTATCCTCACCTCCCACGACTGGCCGGGTAATGTGCGTGAGCTGCGAAATC
TGGCCGAACGTTATGTATTACTCGGTGGTGAAGCGGCCTTCGCCGGCAGCTTAGGTAATGCACCGAGCCTGCATACCAGT
ATGTCGCTGCTGCAACGGGTCGAGTTTTTTGAGCGGGTATTGATAGAAGAGGCCTTAAGCCATAACAAGGGCAGCATTAA
GCAGACCATGGAACAACTCGAACTGCCGCGTAAAACCTTATACGACAAGATGCGTAAGTACGATTTAGACCGCAAACAAT
ATATCAACGCTGACGAGTAA

Upstream 100 bases:

>100_bases
AGTCTATGCAGGGGCAAATTAATGTTGCCAATGCCGAGGACGGCGGCGCCATTTTCCATATTATTTTACCGATTTATTTA
GCCGAGGAACGTCAGTCATC

Downstream 100 bases:

>100_bases
TACTGTCGGTGCCAATAAAAACCCCGCAAACCGATTCACGGCTGCGGGGTTTGCTTTATCTAAGGAACCTCAAGCTAGCA
TTTCAATGCTGATGTATCAA

Product: two component, sigma54 specific, Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MSLPNSIQDYSVLIIDDEPHIGTVLVQLFELEGIKAFATTDPKGIAKLLDRDWAGVVISDVNMPQLDGISLMQQIRQQDP
DLPVVLLTGFGDIAMAVNALKQGAYDFLEKPFNNEHMLDVVKRALDKRSLTLENRKLKKELESHNVPGPRILGHSVGILR
MRHIIDQVIDTPADVLIEGETGTGKELVARYLHDHSSRNQANFVAINCGAIPENLIESELFGAEAGAFTGVDKLRIGKFE
YANGGTLFLDEIESTPLSLQVKLLRVLEDRKVERLGSNKSIHLDIRVIAATKVDLKSLCDTGEFRQDLLYRLNLVTVPIP
PLRDRREDIPLLFLHFARMASARYHKALIALNAEQNAILTSHDWPGNVRELRNLAERYVLLGGEAAFAGSLGNAPSLHTS
MSLLQRVEFFERVLIEEALSHNKGSIKQTMEQLELPRKTLYDKMRKYDLDRKQYINADE

Sequences:

>Translated_459_residues
MSLPNSIQDYSVLIIDDEPHIGTVLVQLFELEGIKAFATTDPKGIAKLLDRDWAGVVISDVNMPQLDGISLMQQIRQQDP
DLPVVLLTGFGDIAMAVNALKQGAYDFLEKPFNNEHMLDVVKRALDKRSLTLENRKLKKELESHNVPGPRILGHSVGILR
MRHIIDQVIDTPADVLIEGETGTGKELVARYLHDHSSRNQANFVAINCGAIPENLIESELFGAEAGAFTGVDKLRIGKFE
YANGGTLFLDEIESTPLSLQVKLLRVLEDRKVERLGSNKSIHLDIRVIAATKVDLKSLCDTGEFRQDLLYRLNLVTVPIP
PLRDRREDIPLLFLHFARMASARYHKALIALNAEQNAILTSHDWPGNVRELRNLAERYVLLGGEAAFAGSLGNAPSLHTS
MSLLQRVEFFERVLIEEALSHNKGSIKQTMEQLELPRKTLYDKMRKYDLDRKQYINADE
>Mature_458_residues
SLPNSIQDYSVLIIDDEPHIGTVLVQLFELEGIKAFATTDPKGIAKLLDRDWAGVVISDVNMPQLDGISLMQQIRQQDPD
LPVVLLTGFGDIAMAVNALKQGAYDFLEKPFNNEHMLDVVKRALDKRSLTLENRKLKKELESHNVPGPRILGHSVGILRM
RHIIDQVIDTPADVLIEGETGTGKELVARYLHDHSSRNQANFVAINCGAIPENLIESELFGAEAGAFTGVDKLRIGKFEY
ANGGTLFLDEIESTPLSLQVKLLRVLEDRKVERLGSNKSIHLDIRVIAATKVDLKSLCDTGEFRQDLLYRLNLVTVPIPP
LRDRREDIPLLFLHFARMASARYHKALIALNAEQNAILTSHDWPGNVRELRNLAERYVLLGGEAAFAGSLGNAPSLHTSM
SLLQRVEFFERVLIEEALSHNKGSIKQTMEQLELPRKTLYDKMRKYDLDRKQYINADE

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. When activated by dctB acts in conjunction with sigma-54 to activate the transcription of dctA [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=452, Percent_Identity=38.9380530973451, Blast_Score=321, Evalue=8e-89,
Organism=Escherichia coli, GI1790299, Length=469, Percent_Identity=36.2473347547974, Blast_Score=290, Evalue=1e-79,
Organism=Escherichia coli, GI1790437, Length=449, Percent_Identity=38.0846325167038, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI1788905, Length=446, Percent_Identity=36.9955156950673, Blast_Score=279, Evalue=2e-76,
Organism=Escherichia coli, GI1789087, Length=339, Percent_Identity=41.5929203539823, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI87082117, Length=272, Percent_Identity=47.7941176470588, Blast_Score=232, Evalue=5e-62,
Organism=Escherichia coli, GI1789233, Length=321, Percent_Identity=39.5638629283489, Blast_Score=218, Evalue=9e-58,
Organism=Escherichia coli, GI1786524, Length=244, Percent_Identity=46.3114754098361, Blast_Score=201, Evalue=9e-53,
Organism=Escherichia coli, GI87081872, Length=238, Percent_Identity=42.8571428571429, Blast_Score=194, Evalue=8e-51,
Organism=Escherichia coli, GI87082152, Length=339, Percent_Identity=36.8731563421829, Blast_Score=194, Evalue=9e-51,
Organism=Escherichia coli, GI1787583, Length=321, Percent_Identity=36.7601246105919, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI87081858, Length=308, Percent_Identity=30.8441558441558, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1789828, Length=226, Percent_Identity=37.6106194690265, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1789809, Length=122, Percent_Identity=23.7704918032787, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51538; Mature: 51407

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPNSIQDYSVLIIDDEPHIGTVLVQLFELEGIKAFATTDPKGIAKLLDRDWAGVVISD
CCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHCCCCCCEEEEC
VNMPQLDGISLMQQIRQQDPDLPVVLLTGFGDIAMAVNALKQGAYDFLEKPFNNEHMLDV
CCCCCCCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
VKRALDKRSLTLENRKLKKELESHNVPGPRILGHSVGILRMRHIIDQVIDTPADVLIEGE
HHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHCHHHHHHHHHHHHHHHCCCCCEEEECC
TGTGKELVARYLHDHSSRNQANFVAINCGAIPENLIESELFGAEAGAFTGVDKLRIGKFE
CCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHEECCEE
YANGGTLFLDEIESTPLSLQVKLLRVLEDRKVERLGSNKSIHLDIRVIAATKVDLKSLCD
ECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECHHHHHHHHC
TGEFRQDLLYRLNLVTVPIPPLRDRREDIPLLFLHFARMASARYHKALIALNAEQNAILT
CHHHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCEEEE
SHDWPGNVRELRNLAERYVLLGGEAAFAGSLGNAPSLHTSMSLLQRVEFFERVLIEEALS
CCCCCCCHHHHHHHHHHHEEECCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
HNKGSIKQTMEQLELPRKTLYDKMRKYDLDRKQYINADE
CCCCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHCCCCCC
>Mature Secondary Structure 
SLPNSIQDYSVLIIDDEPHIGTVLVQLFELEGIKAFATTDPKGIAKLLDRDWAGVVISD
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHCCCCCCEEEEC
VNMPQLDGISLMQQIRQQDPDLPVVLLTGFGDIAMAVNALKQGAYDFLEKPFNNEHMLDV
CCCCCCCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
VKRALDKRSLTLENRKLKKELESHNVPGPRILGHSVGILRMRHIIDQVIDTPADVLIEGE
HHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHCHHHHHHHHHHHHHHHCCCCCEEEECC
TGTGKELVARYLHDHSSRNQANFVAINCGAIPENLIESELFGAEAGAFTGVDKLRIGKFE
CCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHEECCEE
YANGGTLFLDEIESTPLSLQVKLLRVLEDRKVERLGSNKSIHLDIRVIAATKVDLKSLCD
ECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECHHHHHHHHC
TGEFRQDLLYRLNLVTVPIPPLRDRREDIPLLFLHFARMASARYHKALIALNAEQNAILT
CHHHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCEEEE
SHDWPGNVRELRNLAERYVLLGGEAAFAGSLGNAPSLHTSMSLLQRVEFFERVLIEEALS
CCCCCCCHHHHHHHHHHHEEECCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
HNKGSIKQTMEQLELPRKTLYDKMRKYDLDRKQYINADE
CCCCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431 [H]