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The map label for this gene is engA [H]

Identifier: 117919682

GI number: 117919682

Start: 1437022

End: 1438488

Strand: Direct

Name: engA [H]

Synonym: Shewana3_1233

Alternate gene names: 117919682

Gene position: 1437022-1438488 (Clockwise)

Preceding gene: 117919681

Following gene: 117919684

Centisome position: 28.9

GC content: 51.33

Gene sequence:

>1467_bases
ATGATCCCTGTAGTGGCCCTTGTTGGTCGGCCGAACGTCGGTAAATCCACTTTATTTAACCGCCTTACGCGTACGCGTGA
TGCGCTGGTTGCTGACTTTCCTGGCCTAACACGTGACCGTAAATATGGTCGAGCATTCCTATCCGGCTATGAGTTTATCG
TGGTGGATACCGGCGGTATCGACGGCACCGAAGAGGGGATCGAAACTAAGATGGCCGAGCAGTCCCTTGCCGCTATCGAA
GAAGCCGATGTTGTCTTATTTATGACCGATGCGCGCGCGGGCTTAACCGCCGCGGATTTGTCTATCGCTCAACACTTACG
TAGCCGTCAAAAAACCACTTTCGTGGTCGCTAACAAGATTGACGGTATCGATGCCGATTCTGCCTGCGCCGAGTTTTGGT
CGTTAGGTTTAGGTGAGGTCTACCAAATGGCTGCCGCCCAAGGCCGCGGCGTGACCAACATGATTGAGTACGCCTTAACT
CCTTATGCTGAAGCGATGGGGATTGAACGCCAAGGCGAAGAGGAAGAGGTCGACGAGCGTCAGTACACCGAAGAAGAAGC
CGAAGCCGAGCAGAAGCGTCTGCAGGATTTACCGATTAAGCTTGCGATTATCGGTAAGCCTAACGTAGGTAAATCGACGC
TGACTAACCGTATTTTAGGTGAAGAGCGTGTGGTGGTTTACGACGAGCCGGGCACCACTCGCGACAGTATTTACATTCCG
ATGGAACGCGATGGCCGCGAATACGTGATTATCGATACAGCTGGTGTGCGTCGCCGCAGTAAAGTCCATGAAGTGATTGA
AAAATTCTCGGTGATCAAAACCCTAAAAGCGGTTGAAGATGCCAACGTTGTGCTGCTGATCATCGATGCCCGTGAAGGGA
TTGCCGAGCAGGATTTAGGTCTATTAGGTTTTGCTTTGAACGCGGGCCGCGCCTTAGTTATCGCCGTCAACAAGTGGGAC
GGTATCGATCAGGGCATTAAAGACCGGGTTAAGAGTGAACTCGACCGCCGTTTAGGCTTTATCGACTTTGCTCGTATTCA
CTTTATTTCGGCGCTACATGGTACGGGCGTTGGCCATCTGTTTGAGTCGATTGAAGAAGCTTACGACAGTGCGACTCGCC
GCGTGAGCACCTCTATGCTGACCCGCATTATGCAAATGTCGCAGGATGACCATCAGCCACCATTGGTGAACGGTCGCCGT
GTGAAACTGAAATACGCCCACGCCGGTGGTTATAACCCGCCAATTGTGGTTATTCACGGTAACCAAGTCAGCAAGCTACC
GGATTCTTACAAGCGCTACATGATGAACTACTTCCGTCGTTCATTAAAAGTGGTCGGTACGCCAATTCAGCTGCGTTTCC
AAGAGGGTGATAACCCGTTTGAAAACAAGGTTGAAAAGCTGACCATGAGCCAAGAGCGTCGTCGTAAGCGCGCACTGAGC
CATATTAAAGATCGCAAGACAAAGTAA

Upstream 100 bases:

>100_bases
GCTGTTGTAACACTTCCTTAGTTAAAAGTGTTATCCTTGTAGAGCCCCTGGAAGTGTGTTCCGGGGGCTTTTTATTGAAA
AGTTTTTTAGAGGCAAAATC

Downstream 100 bases:

>100_bases
ATCTGTGCTATTGGCTTAAGCGGAACATAAAAAAGGAACCCTAGGGTTCCTTTTTTATTGGCGTATTTTAGGGCGCAATC
ATAAGTCTTGTTTAGATAAA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAFLSGYEFIVVDTGGIDGTEEGIETKMAEQSLAAIE
EADVVLFMTDARAGLTAADLSIAQHLRSRQKTTFVVANKIDGIDADSACAEFWSLGLGEVYQMAAAQGRGVTNMIEYALT
PYAEAMGIERQGEEEEVDERQYTEEEAEAEQKRLQDLPIKLAIIGKPNVGKSTLTNRILGEERVVVYDEPGTTRDSIYIP
MERDGREYVIIDTAGVRRRSKVHEVIEKFSVIKTLKAVEDANVVLLIIDAREGIAEQDLGLLGFALNAGRALVIAVNKWD
GIDQGIKDRVKSELDRRLGFIDFARIHFISALHGTGVGHLFESIEEAYDSATRRVSTSMLTRIMQMSQDDHQPPLVNGRR
VKLKYAHAGGYNPPIVVIHGNQVSKLPDSYKRYMMNYFRRSLKVVGTPIQLRFQEGDNPFENKVEKLTMSQERRRKRALS
HIKDRKTK

Sequences:

>Translated_488_residues
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAFLSGYEFIVVDTGGIDGTEEGIETKMAEQSLAAIE
EADVVLFMTDARAGLTAADLSIAQHLRSRQKTTFVVANKIDGIDADSACAEFWSLGLGEVYQMAAAQGRGVTNMIEYALT
PYAEAMGIERQGEEEEVDERQYTEEEAEAEQKRLQDLPIKLAIIGKPNVGKSTLTNRILGEERVVVYDEPGTTRDSIYIP
MERDGREYVIIDTAGVRRRSKVHEVIEKFSVIKTLKAVEDANVVLLIIDAREGIAEQDLGLLGFALNAGRALVIAVNKWD
GIDQGIKDRVKSELDRRLGFIDFARIHFISALHGTGVGHLFESIEEAYDSATRRVSTSMLTRIMQMSQDDHQPPLVNGRR
VKLKYAHAGGYNPPIVVIHGNQVSKLPDSYKRYMMNYFRRSLKVVGTPIQLRFQEGDNPFENKVEKLTMSQERRRKRALS
HIKDRKTK
>Mature_488_residues
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAFLSGYEFIVVDTGGIDGTEEGIETKMAEQSLAAIE
EADVVLFMTDARAGLTAADLSIAQHLRSRQKTTFVVANKIDGIDADSACAEFWSLGLGEVYQMAAAQGRGVTNMIEYALT
PYAEAMGIERQGEEEEVDERQYTEEEAEAEQKRLQDLPIKLAIIGKPNVGKSTLTNRILGEERVVVYDEPGTTRDSIYIP
MERDGREYVIIDTAGVRRRSKVHEVIEKFSVIKTLKAVEDANVVLLIIDAREGIAEQDLGLLGFALNAGRALVIAVNKWD
GIDQGIKDRVKSELDRRLGFIDFARIHFISALHGTGVGHLFESIEEAYDSATRRVSTSMLTRIMQMSQDDHQPPLVNGRR
VKLKYAHAGGYNPPIVVIHGNQVSKLPDSYKRYMMNYFRRSLKVVGTPIQLRFQEGDNPFENKVEKLTMSQERRRKRALS
HIKDRKTK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=490, Percent_Identity=71.2244897959184, Blast_Score=725, Evalue=0.0,
Organism=Escherichia coli, GI2367268, Length=103, Percent_Identity=38.8349514563107, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=144, Percent_Identity=34.0277777777778, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 54647; Mature: 54647

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAFLSGYEFIVVDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEEEEECCCC
DGTEEGIETKMAEQSLAAIEEADVVLFMTDARAGLTAADLSIAQHLRSRQKTTFVVANKI
CCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECC
DGIDADSACAEFWSLGLGEVYQMAAAQGRGVTNMIEYALTPYAEAMGIERQGEEEEVDER
CCCCCHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHCCCCCCCHHHHHHH
QYTEEEAEAEQKRLQDLPIKLAIIGKPNVGKSTLTNRILGEERVVVYDEPGTTRDSIYIP
HHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCCCEEEEECCCCCCCCCEEEE
MERDGREYVIIDTAGVRRRSKVHEVIEKFSVIKTLKAVEDANVVLLIIDAREGIAEQDLG
ECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHCCC
LLGFALNAGRALVIAVNKWDGIDQGIKDRVKSELDRRLGFIDFARIHFISALHGTGVGHL
CEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHH
FESIEEAYDSATRRVSTSMLTRIMQMSQDDHQPPLVNGRRVKLKYAHAGGYNPPIVVIHG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEC
NQVSKLPDSYKRYMMNYFRRSLKVVGTPIQLRFQEGDNPFENKVEKLTMSQERRRKRALS
CCHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
HIKDRKTK
HHHHCCCC
>Mature Secondary Structure
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAFLSGYEFIVVDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEEEEECCCC
DGTEEGIETKMAEQSLAAIEEADVVLFMTDARAGLTAADLSIAQHLRSRQKTTFVVANKI
CCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECC
DGIDADSACAEFWSLGLGEVYQMAAAQGRGVTNMIEYALTPYAEAMGIERQGEEEEVDER
CCCCCHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHCCCCCCCHHHHHHH
QYTEEEAEAEQKRLQDLPIKLAIIGKPNVGKSTLTNRILGEERVVVYDEPGTTRDSIYIP
HHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCCCEEEEECCCCCCCCCEEEE
MERDGREYVIIDTAGVRRRSKVHEVIEKFSVIKTLKAVEDANVVLLIIDAREGIAEQDLG
ECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHCCC
LLGFALNAGRALVIAVNKWDGIDQGIKDRVKSELDRRLGFIDFARIHFISALHGTGVGHL
CEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHH
FESIEEAYDSATRRVSTSMLTRIMQMSQDDHQPPLVNGRRVKLKYAHAGGYNPPIVVIHG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEC
NQVSKLPDSYKRYMMNYFRRSLKVVGTPIQLRFQEGDNPFENKVEKLTMSQERRRKRALS
CCHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
HIKDRKTK
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA