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The map label for this gene is fbp [H]

Identifier: 117919100

GI number: 117919100

Start: 765288

End: 766280

Strand: Reverse

Name: fbp [H]

Synonym: Shewana3_0648

Alternate gene names: 117919100

Gene position: 766280-765288 (Counterclockwise)

Preceding gene: 117919102

Following gene: 117919099

Centisome position: 15.41

GC content: 50.05

Gene sequence:

>993_bases
ATGCAGACTCTTGCCCAGCACTTAACCTCAAAGGCAGTGAACGAATCCCTCTCGCAACTGATTTTGACCTTAGCCGACAC
CTCCAAAGCCATCAGCCATGCCGTGCGCCATGGTGCCTTAGCCGGTGTGTTAGGCGCGACCGAACAGGAAAACGTGCAAG
GTGAAACCCAGAAAAAACTGGATATCATTACCAACGATATGCTCAAAGATGCATTAAAAGCCGACGGCACAGTGCGCGGC
TTAGCCTCTGAGGAAGAAGATCATGTGGTTGAAGTCTGCGCCAATGGTCAATATCTGGTATGTTTCGACCCTTTAGATGG
TTCATCGAATATCGATATCAACTCACTGGTCGGCACGATTTTCTCTGTTCTGCCCGCCCCACAGGGCGAGTTGACTGAAA
CAAGCTTTTTGCAATCGGGTCGCAATCAGTTAGCCGCAGGTTATGTGCTCTACGGCCCATCAACCATGCTCGCCCTCACC
ACAGGCCAAGGCGTGCAACTCTTTACCCTGCACCCAGAAACCAACGAATTTTTACTGACCAACGCGGCCATGAGCATCAG
CCCAGACACCCAAGAGTTCGCCATTAACATGTCGAACCAACGTTTTTGGGAAGCGCCAATGCAGACCTACATCGCCGATT
TACTGCTAGGCAAAATTGGCCCGCGCGAAAAATCCTTCAACATGCGCTGGATTGCCGCCATGGTCGGTGACGTGCACCGC
GTACTTTCTCGCGGCGGTATCTTTACTTATCCAACCGACAATAAAGATCCGAAAAAGCCATACAAGCTGCGTTTAATGTA
CGAAGCCAACCCAATGGCCCTTTTAGTCGAGCAAGCTGGCGGTAAAGCCTCTACGGGTTATGAAACCATTTTGGATATTC
AACCAACGCAAATTCACCAACGCGTTGCAGTTATCCTAGGTAGCGCCAATGAAGTAGACGCTTGCCTAAGCTACCATGGT
TTGGATTACAGTGAAGAACCAAGTCTAGACTAA

Upstream 100 bases:

>100_bases
AAAACCCACAGCAACATCGCTGAAATTGTCGACTAACTGAGTTATTATTCGCGGCAAATAATGAAATTGACCTCAATGTT
GAACCCCTAAAGGACCTAAC

Downstream 100 bases:

>100_bases
GCCGAATCGCTTAAGCTTTGATTTTTTTTCAGATAAAAGCCACTGACCACAGTGGCTTTTTTGTTATCGCAGAATGCGAC
ATTTGAGTTTTATGCGGCTT

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MQTLAQHLTSKAVNESLSQLILTLADTSKAISHAVRHGALAGVLGATEQENVQGETQKKLDIITNDMLKDALKADGTVRG
LASEEEDHVVEVCANGQYLVCFDPLDGSSNIDINSLVGTIFSVLPAPQGELTETSFLQSGRNQLAAGYVLYGPSTMLALT
TGQGVQLFTLHPETNEFLLTNAAMSISPDTQEFAINMSNQRFWEAPMQTYIADLLLGKIGPREKSFNMRWIAAMVGDVHR
VLSRGGIFTYPTDNKDPKKPYKLRLMYEANPMALLVEQAGGKASTGYETILDIQPTQIHQRVAVILGSANEVDACLSYHG
LDYSEEPSLD

Sequences:

>Translated_330_residues
MQTLAQHLTSKAVNESLSQLILTLADTSKAISHAVRHGALAGVLGATEQENVQGETQKKLDIITNDMLKDALKADGTVRG
LASEEEDHVVEVCANGQYLVCFDPLDGSSNIDINSLVGTIFSVLPAPQGELTETSFLQSGRNQLAAGYVLYGPSTMLALT
TGQGVQLFTLHPETNEFLLTNAAMSISPDTQEFAINMSNQRFWEAPMQTYIADLLLGKIGPREKSFNMRWIAAMVGDVHR
VLSRGGIFTYPTDNKDPKKPYKLRLMYEANPMALLVEQAGGKASTGYETILDIQPTQIHQRVAVILGSANEVDACLSYHG
LDYSEEPSLD
>Mature_330_residues
MQTLAQHLTSKAVNESLSQLILTLADTSKAISHAVRHGALAGVLGATEQENVQGETQKKLDIITNDMLKDALKADGTVRG
LASEEEDHVVEVCANGQYLVCFDPLDGSSNIDINSLVGTIFSVLPAPQGELTETSFLQSGRNQLAAGYVLYGPSTMLALT
TGQGVQLFTLHPETNEFLLTNAAMSISPDTQEFAINMSNQRFWEAPMQTYIADLLLGKIGPREKSFNMRWIAAMVGDVHR
VLSRGGIFTYPTDNKDPKKPYKLRLMYEANPMALLVEQAGGKASTGYETILDIQPTQIHQRVAVILGSANEVDACLSYHG
LDYSEEPSLD

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI189083692, Length=301, Percent_Identity=44.1860465116279, Blast_Score=234, Evalue=6e-62,
Organism=Homo sapiens, GI16579888, Length=301, Percent_Identity=44.1860465116279, Blast_Score=234, Evalue=6e-62,
Organism=Homo sapiens, GI22907028, Length=326, Percent_Identity=40.4907975460123, Blast_Score=234, Evalue=8e-62,
Organism=Escherichia coli, GI1790679, Length=313, Percent_Identity=44.7284345047923, Blast_Score=241, Evalue=4e-65,
Organism=Caenorhabditis elegans, GI17508131, Length=305, Percent_Identity=43.2786885245902, Blast_Score=236, Evalue=9e-63,
Organism=Saccharomyces cerevisiae, GI6323409, Length=297, Percent_Identity=41.0774410774411, Blast_Score=226, Evalue=3e-60,
Organism=Drosophila melanogaster, GI45550998, Length=320, Percent_Identity=41.25, Blast_Score=212, Evalue=4e-55,
Organism=Drosophila melanogaster, GI19921562, Length=320, Percent_Identity=41.25, Blast_Score=211, Evalue=4e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 35890; Mature: 35890

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00659 GLYCOSYL_HYDROL_F5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTLAQHLTSKAVNESLSQLILTLADTSKAISHAVRHGALAGVLGATEQENVQGETQKKL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
DIITNDMLKDALKADGTVRGLASEEEDHVVEVCANGQYLVCFDPLDGSSNIDINSLVGTI
HHHHHHHHHHHHHCCCCEECCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCHHHHHHHH
FSVLPAPQGELTETSFLQSGRNQLAAGYVLYGPSTMLALTTGQGVQLFTLHPETNEFLLT
HHHCCCCCCCCHHHHHHHCCCHHHCCCEEEECCCEEEEEECCCCEEEEEECCCCCCEEEE
NAAMSISPDTQEFAINMSNQRFWEAPMQTYIADLLLGKIGPREKSFNMRWIAAMVGDVHR
ECEEECCCCCHHEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
VLSRGGIFTYPTDNKDPKKPYKLRLMYEANPMALLVEQAGGKASTGYETILDIQPTQIHQ
HHHCCCEEECCCCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCEEEEECCHHHHHH
RVAVILGSANEVDACLSYHGLDYSEEPSLD
HHHHEECCCCHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MQTLAQHLTSKAVNESLSQLILTLADTSKAISHAVRHGALAGVLGATEQENVQGETQKKL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
DIITNDMLKDALKADGTVRGLASEEEDHVVEVCANGQYLVCFDPLDGSSNIDINSLVGTI
HHHHHHHHHHHHHCCCCEECCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCHHHHHHHH
FSVLPAPQGELTETSFLQSGRNQLAAGYVLYGPSTMLALTTGQGVQLFTLHPETNEFLLT
HHHCCCCCCCCHHHHHHHCCCHHHCCCEEEECCCEEEEEECCCCEEEEEECCCCCCEEEE
NAAMSISPDTQEFAINMSNQRFWEAPMQTYIADLLLGKIGPREKSFNMRWIAAMVGDVHR
ECEEECCCCCHHEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
VLSRGGIFTYPTDNKDPKKPYKLRLMYEANPMALLVEQAGGKASTGYETILDIQPTQIHQ
HHHCCCEEECCCCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCEEEEECCHHHHHH
RVAVILGSANEVDACLSYHGLDYSEEPSLD
HHHHEECCCCHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA