Click here to switch to the map view.

The map label for this gene is aprE [H]

Identifier: 117918837

GI number: 117918837

Start: 421769

End: 423151

Strand: Reverse

Name: aprE [H]

Synonym: Shewana3_0380

Alternate gene names: 117918837

Gene position: 423151-421769 (Counterclockwise)

Preceding gene: 117918838

Following gene: 117918836

Centisome position: 8.51

GC content: 42.81

Gene sequence:

>1383_bases
ATGAGCAAACACCTCACGGCAAATGATTTAGATATGGTCGATGATGTTTATGGCGCAATTATGACTGATGCTCCTAGTGG
GCACAGATTAATTATTTGGGCTTTAGCTGCCATGGTCGCCTGTTTTTTGTTATGGGCAGGTTTTGCCAAACTCGATAAGG
TGACAACGGGTTCTGGGAAAGTTATCCCTTCTTCTCAAGTTCAAGTCATTCAAAGTCTCGACGGCGGTATCATGCAAGAA
CTCTTTGTGAGAGAAGGGGATATTGTCACTAAAGGGCAACCCCTTGTTAGGATTGATGATACACGTTTTCGTTCTGACTT
TGCTCAACAGGAGCAAGAGGTTTTAGGTTTAAAAACGAATGCAATTCGCATGCGCGCAGAATTAGATAGCATTCTAATCT
CTGATATGACTTCTGACTGGCGTGAGCAAGTAAAAATAACCAAAAAAGCTTTGGTATTCCCCGATAGCATTACAGAAGCA
GAGCCTGCATTAGTTAGGAGGCAGCAAGAAGAATATAATGGGCGCTTAGACAATCTGAGCAACCAACTGGAGATTCTGGT
TCGTCAGATACAACAAAGACAACAAGAAATCGATGACCTTGCCTCAAAAACTACGACCTTAACAACCAGTATGCAGTTGA
TTTCTAGGGAGTTAGAGCTTACGAGGCCTCTGGCTAAAAAAGGGATTGTGCCCGAAGTTGAATTACTTAAACTCGAACGC
GCAGTGAACGATGCCCAAGGGGAATTAAACTCATTGAGACTGCTTAGACCAAAACTGAAAGCAGCATTAGATGAAGCCAT
ATTAAAACGCCGTGAGGCGGTGTTTGTTTATGCCGCAGACCTTCGTGCACAGCTAAACGAAACACAAACTCGATTATCAA
GAATGAACGAAGCCCAAGTTGGTGCCCAGGATAAGGTAAGCAAAGCGGTGATTACATCGCCGGTAAATGGCACGATCAAA
ACTGTGCATATCAATACGTTAGGAGGAGTTGTCCAACCGGGTGTTGATATTATTGAAATTGTCCCATCCGAAGATCAACT
ATTGATAGAAACCAAAATCCTTCCTAAGGATATTGCGTTTTTACACACAGGTTTACCTGCAGTCGTTAAGGTAACGGCAT
ATGATTTTACTCGTTACGGGGGTCTTAAAGGTACAGTCGAACATATTAGTGCCGATACATCACAGGACGATGAGGGAAAT
AGCTTCTACCTTATAAAGGTGAGAACCGAAGAATCAAGTTTAATCAAAGACGATGGCACGCAGATGCCAATTATACCGGG
GATGTTAACGACCGTTGATGTCATAACCGGACAAAGATCCATTCTTGAGTACATTTTAAATCCAATTTTAAGGGCTAAGG
ACACAGCGCTCAGAGAGCGTTAA

Upstream 100 bases:

>100_bases
GAATTATTGTGCTGGAACGCGGCCATGTGGTTGCCGACGGTCCTAAAGCCGAAGTGTTAGAAAAACTCAATTTTGGCCTA
GTTAATGGAGGCGCCAGAAA

Downstream 100 bases:

>100_bases
GCCTGTTATAAACCGGGAGGTTTGCAATGAAGACTTTAGTAAGACGACAATTTCAATGTTCAAAAATAGCTGTGTTGTTA
TCAGCTATCTTGCTTCCACT

Product: HlyD family type I secretion membrane fusion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MSKHLTANDLDMVDDVYGAIMTDAPSGHRLIIWALAAMVACFLLWAGFAKLDKVTTGSGKVIPSSQVQVIQSLDGGIMQE
LFVREGDIVTKGQPLVRIDDTRFRSDFAQQEQEVLGLKTNAIRMRAELDSILISDMTSDWREQVKITKKALVFPDSITEA
EPALVRRQQEEYNGRLDNLSNQLEILVRQIQQRQQEIDDLASKTTTLTTSMQLISRELELTRPLAKKGIVPEVELLKLER
AVNDAQGELNSLRLLRPKLKAALDEAILKRREAVFVYAADLRAQLNETQTRLSRMNEAQVGAQDKVSKAVITSPVNGTIK
TVHINTLGGVVQPGVDIIEIVPSEDQLLIETKILPKDIAFLHTGLPAVVKVTAYDFTRYGGLKGTVEHISADTSQDDEGN
SFYLIKVRTEESSLIKDDGTQMPIIPGMLTTVDVITGQRSILEYILNPILRAKDTALRER

Sequences:

>Translated_460_residues
MSKHLTANDLDMVDDVYGAIMTDAPSGHRLIIWALAAMVACFLLWAGFAKLDKVTTGSGKVIPSSQVQVIQSLDGGIMQE
LFVREGDIVTKGQPLVRIDDTRFRSDFAQQEQEVLGLKTNAIRMRAELDSILISDMTSDWREQVKITKKALVFPDSITEA
EPALVRRQQEEYNGRLDNLSNQLEILVRQIQQRQQEIDDLASKTTTLTTSMQLISRELELTRPLAKKGIVPEVELLKLER
AVNDAQGELNSLRLLRPKLKAALDEAILKRREAVFVYAADLRAQLNETQTRLSRMNEAQVGAQDKVSKAVITSPVNGTIK
TVHINTLGGVVQPGVDIIEIVPSEDQLLIETKILPKDIAFLHTGLPAVVKVTAYDFTRYGGLKGTVEHISADTSQDDEGN
SFYLIKVRTEESSLIKDDGTQMPIIPGMLTTVDVITGQRSILEYILNPILRAKDTALRER
>Mature_459_residues
SKHLTANDLDMVDDVYGAIMTDAPSGHRLIIWALAAMVACFLLWAGFAKLDKVTTGSGKVIPSSQVQVIQSLDGGIMQEL
FVREGDIVTKGQPLVRIDDTRFRSDFAQQEQEVLGLKTNAIRMRAELDSILISDMTSDWREQVKITKKALVFPDSITEAE
PALVRRQQEEYNGRLDNLSNQLEILVRQIQQRQQEIDDLASKTTTLTTSMQLISRELELTRPLAKKGIVPEVELLKLERA
VNDAQGELNSLRLLRPKLKAALDEAILKRREAVFVYAADLRAQLNETQTRLSRMNEAQVGAQDKVSKAVITSPVNGTIKT
VHINTLGGVVQPGVDIIEIVPSEDQLLIETKILPKDIAFLHTGLPAVVKVTAYDFTRYGGLKGTVEHISADTSQDDEGNS
FYLIKVRTEESSLIKDDGTQMPIIPGMLTTVDVITGQRSILEYILNPILRAKDTALRER

Specific function: Involved in the secretion of alkaline protease [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 51137; Mature: 51005

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKHLTANDLDMVDDVYGAIMTDAPSGHRLIIWALAAMVACFLLWAGFAKLDKVTTGSGK
CCCCCCCCCHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCEECCCCC
VIPSSQVQVIQSLDGGIMQELFVREGDIVTKGQPLVRIDDTRFRSDFAQQEQEVLGLKTN
CCCCHHHHHHHHHCCHHHHHHHHCCCCEEECCCCEEEECCHHHHHHHHHHHHHHHCCCHH
AIRMRAELDSILISDMTSDWREQVKITKKALVFPDSITEAEPALVRRQQEEYNGRLDNLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHCCCHHHHH
NQLEILVRQIQQRQQEIDDLASKTTTLTTSMQLISRELELTRPLAKKGIVPEVELLKLER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
AVNDAQGELNSLRLLRPKLKAALDEAILKRREAVFVYAADLRAQLNETQTRLSRMNEAQV
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEHHHHHHHHHHHHHHHHHHHHHC
GAQDKVSKAVITSPVNGTIKTVHINTLGGVVQPGVDIIEIVPSEDQLLIETKILPKDIAF
CCHHHHHHHHEECCCCCCEEEEEEECCCCCCCCCCCEEEEECCCCCEEEEEECCHHHHHH
LHTGLPAVVKVTAYDFTRYGGLKGTVEHISADTSQDDEGNSFYLIKVRTEESSLIKDDGT
HHCCCCHHEEEEEHHHHHHCCCCCHHHHHCCCCCCCCCCCEEEEEEEECCCCHHHCCCCC
QMPIIPGMLTTVDVITGQRSILEYILNPILRAKDTALRER
CCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKHLTANDLDMVDDVYGAIMTDAPSGHRLIIWALAAMVACFLLWAGFAKLDKVTTGSGK
CCCCCCCCHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCEECCCCC
VIPSSQVQVIQSLDGGIMQELFVREGDIVTKGQPLVRIDDTRFRSDFAQQEQEVLGLKTN
CCCCHHHHHHHHHCCHHHHHHHHCCCCEEECCCCEEEECCHHHHHHHHHHHHHHHCCCHH
AIRMRAELDSILISDMTSDWREQVKITKKALVFPDSITEAEPALVRRQQEEYNGRLDNLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHCCCHHHHH
NQLEILVRQIQQRQQEIDDLASKTTTLTTSMQLISRELELTRPLAKKGIVPEVELLKLER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
AVNDAQGELNSLRLLRPKLKAALDEAILKRREAVFVYAADLRAQLNETQTRLSRMNEAQV
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEHHHHHHHHHHHHHHHHHHHHHC
GAQDKVSKAVITSPVNGTIKTVHINTLGGVVQPGVDIIEIVPSEDQLLIETKILPKDIAF
CCHHHHHHHHEECCCCCCEEEEEEECCCCCCCCCCCEEEEECCCCCEEEEEECCHHHHHH
LHTGLPAVVKVTAYDFTRYGGLKGTVEHISADTSQDDEGNSFYLIKVRTEESSLIKDDGT
HHCCCCHHEEEEEHHHHHHCCCCCHHHHHCCCCCCCCCCCEEEEEEEECCCCHHHCCCCC
QMPIIPGMLTTVDVITGQRSILEYILNPILRAKDTALRER
CCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]