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The map label for this gene is yhcK [H]

Identifier: 117918765

GI number: 117918765

Start: 346356

End: 348101

Strand: Reverse

Name: yhcK [H]

Synonym: Shewana3_0308

Alternate gene names: 117918765

Gene position: 348101-346356 (Counterclockwise)

Preceding gene: 117918766

Following gene: 117918764

Centisome position: 7.0

GC content: 50.11

Gene sequence:

>1746_bases
ATGAGAATCTGTATGGGCCGAGCGACATGGATGGGTTTACTCACATTGGGAGCATTGCTGCTCATCTGCGTGGCATTCAC
GACCAAGGCCGCAACGGCAGAGATATCCTGGCAGGATAATACGACCAGTCTCACCGACTTTCCGATGAGCTATTTTGTCG
ATACCTCGGAGAACATGCCCTTTACTGAAGTCACGCAACAAACCTTTATCGACTCCAGCAATCGCGTATCTCTTGGCACA
GCCGCCATCAAAACCTGGGCAAAGATCCCCTTAGTTAATACCAGCAATAGCCCACAAACCCTGTATCTGCACCATCCCTA
CGCCTATCACAATCGCCAGGTTGGACTCTATGAAACAGTCGATGGGCAGGAGACACTGCGCCGAATACTCGACCTCGACG
ACCCTAGCACCTATGGCTGGCTCTATGGCGGTGCGGCGGTATTTGAGGTCACACTCGCGCCACACCAAAAGAAAACCCTA
TACGTCGAGAGCGTGTCCTTTTCACACCAATGGTTCTCAATCGATTTATACAACAAGGAACAATCCCAACGAGCATTGCT
CGGCAGCTTTACCGATATTGCGGTTATGGTGGGCATGCTACTGGCGCTGATTATCTACAACCTATTGTTATTTATGTATT
CCCGCCAGCGGGACAATCTGTTTTACGCCTGTTACTTAATCTCAGGCGGGATCTGGATTGCCCTCTCCTATGGGCTGGTC
GCCGAAGTATTCGCGTTTTACGGCTCAGCCAGCCTGTATTGGCACCTTACCCTGATGACCATGCCCATCTTTTTGATTTT
ATTTATGATGGATATTTTCGAGACTCGGCAACATTATCGCTTCGAGCATTATGCCCTCGTCTTTGTGCTCGTCCTGTTAG
TGGCCGAATTTTGTTATGGCGTGGTGGATATCATTGGTGCGCTGCGCTATTCCAGCAGCCTGGCTGCCTTGATGATGTTA
ACTACCCTCTCGGTCACGATTTCGCTGGTGATAAAACGACATCCCATCGCGAAATACTTTCTCCTCGGTCACTGTCTTTT
CGTCGGTTTTAGTGGTCTTGCGGTGATGTTTTACAAAGGCCGCGCCGAGTTTAGCTATCTCTCAAGCCACGGTGTCGGCG
TGGGCATTATGCTAGAGGCGCTAGTGCTTGCACTTATCATCGCCTATCGCATCCGTCTGCTCGAAGAAATTAAAGCCTCG
CAGGAAGAACTTAAATATCAAGCGGCGACAGATTCGCTCACCCATTTATTTAATCGCCGTCATTTCCACAAAGAAGCGCA
GCGGATCTATATGCAGGCTAGCGTGACACAACAACCCATGGCGGTGATTATCTGTGATATCGACCTGTTCAAACGGGTCA
ACGACAAATACGGCCATCTGATGGGCGATCAGGTCATTATCGATATTGCCACCACACTCAAACAGCATGCGCGTAAATGT
GACATAGTGGCGCGCTACGGCGGCGAAGAATTTATTATGTTGCTACATGACGTGTCCCTTACCGAGGCACACCAATGCGC
CGAACGCATTCGCAGCGCCGTTGCTGAGCTAAGCTTTATGGCCGAGACGCAAGAAGCCTTCACTGTCACCCTGAGTCTTG
GGGTGGCGGCCGTTGATTTTGTCCATCCCCTAGAGCATGCCATCAAGCTGGCGGACGATGCCCTGTATCGCGCTAAACAT
CAGGGCCGTAACAATGTGCAATCCAGCGAAATCAATCTATTAGAGATAAAGGAAGGCATAAACTAA

Upstream 100 bases:

>100_bases
CTTTATTTAACTCGATAAAATCCCCTAATCTCGCTGATTTTTTTTCATTCTCAGTACGCTATTGATACTTTATGGCATAC
TTGTTAGCTCAACGTTAATC

Downstream 100 bases:

>100_bases
CACGGCAAACCAAAGCGAGTGCCATCGCCTACTCTACAAAATCGACTCGGTCTATAGGGTGCTGTGTCGGCTTTGTGAGC
TATCACTCGCTTTTACCACG

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 581; Mature: 581

Protein sequence:

>581_residues
MRICMGRATWMGLLTLGALLLICVAFTTKAATAEISWQDNTTSLTDFPMSYFVDTSENMPFTEVTQQTFIDSSNRVSLGT
AAIKTWAKIPLVNTSNSPQTLYLHHPYAYHNRQVGLYETVDGQETLRRILDLDDPSTYGWLYGGAAVFEVTLAPHQKKTL
YVESVSFSHQWFSIDLYNKEQSQRALLGSFTDIAVMVGMLLALIIYNLLLFMYSRQRDNLFYACYLISGGIWIALSYGLV
AEVFAFYGSASLYWHLTLMTMPIFLILFMMDIFETRQHYRFEHYALVFVLVLLVAEFCYGVVDIIGALRYSSSLAALMML
TTLSVTISLVIKRHPIAKYFLLGHCLFVGFSGLAVMFYKGRAEFSYLSSHGVGVGIMLEALVLALIIAYRIRLLEEIKAS
QEELKYQAATDSLTHLFNRRHFHKEAQRIYMQASVTQQPMAVIICDIDLFKRVNDKYGHLMGDQVIIDIATTLKQHARKC
DIVARYGGEEFIMLLHDVSLTEAHQCAERIRSAVAELSFMAETQEAFTVTLSLGVAAVDFVHPLEHAIKLADDALYRAKH
QGRNNVQSSEINLLEIKEGIN

Sequences:

>Translated_581_residues
MRICMGRATWMGLLTLGALLLICVAFTTKAATAEISWQDNTTSLTDFPMSYFVDTSENMPFTEVTQQTFIDSSNRVSLGT
AAIKTWAKIPLVNTSNSPQTLYLHHPYAYHNRQVGLYETVDGQETLRRILDLDDPSTYGWLYGGAAVFEVTLAPHQKKTL
YVESVSFSHQWFSIDLYNKEQSQRALLGSFTDIAVMVGMLLALIIYNLLLFMYSRQRDNLFYACYLISGGIWIALSYGLV
AEVFAFYGSASLYWHLTLMTMPIFLILFMMDIFETRQHYRFEHYALVFVLVLLVAEFCYGVVDIIGALRYSSSLAALMML
TTLSVTISLVIKRHPIAKYFLLGHCLFVGFSGLAVMFYKGRAEFSYLSSHGVGVGIMLEALVLALIIAYRIRLLEEIKAS
QEELKYQAATDSLTHLFNRRHFHKEAQRIYMQASVTQQPMAVIICDIDLFKRVNDKYGHLMGDQVIIDIATTLKQHARKC
DIVARYGGEEFIMLLHDVSLTEAHQCAERIRSAVAELSFMAETQEAFTVTLSLGVAAVDFVHPLEHAIKLADDALYRAKH
QGRNNVQSSEINLLEIKEGIN
>Mature_581_residues
MRICMGRATWMGLLTLGALLLICVAFTTKAATAEISWQDNTTSLTDFPMSYFVDTSENMPFTEVTQQTFIDSSNRVSLGT
AAIKTWAKIPLVNTSNSPQTLYLHHPYAYHNRQVGLYETVDGQETLRRILDLDDPSTYGWLYGGAAVFEVTLAPHQKKTL
YVESVSFSHQWFSIDLYNKEQSQRALLGSFTDIAVMVGMLLALIIYNLLLFMYSRQRDNLFYACYLISGGIWIALSYGLV
AEVFAFYGSASLYWHLTLMTMPIFLILFMMDIFETRQHYRFEHYALVFVLVLLVAEFCYGVVDIIGALRYSSSLAALMML
TTLSVTISLVIKRHPIAKYFLLGHCLFVGFSGLAVMFYKGRAEFSYLSSHGVGVGIMLEALVLALIIAYRIRLLEEIKAS
QEELKYQAATDSLTHLFNRRHFHKEAQRIYMQASVTQQPMAVIICDIDLFKRVNDKYGHLMGDQVIIDIATTLKQHARKC
DIVARYGGEEFIMLLHDVSLTEAHQCAERIRSAVAELSFMAETQEAFTVTLSLGVAAVDFVHPLEHAIKLADDALYRAKH
QGRNNVQSSEINLLEIKEGIN

Specific function: Unknown

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI145693134, Length=270, Percent_Identity=31.4814814814815, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI87081881, Length=171, Percent_Identity=42.1052631578947, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI87082007, Length=214, Percent_Identity=32.7102803738318, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1787262, Length=165, Percent_Identity=42.4242424242424, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788381, Length=177, Percent_Identity=35.0282485875706, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786584, Length=169, Percent_Identity=29.585798816568, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1788085, Length=161, Percent_Identity=32.9192546583851, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787802, Length=177, Percent_Identity=29.3785310734463, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1787541, Length=174, Percent_Identity=33.9080459770115, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1787816, Length=163, Percent_Identity=34.3558282208589, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1788956, Length=167, Percent_Identity=34.1317365269461, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081974, Length=189, Percent_Identity=29.6296296296296, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI87081977, Length=168, Percent_Identity=26.7857142857143, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 65715; Mature: 65715

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRICMGRATWMGLLTLGALLLICVAFTTKAATAEISWQDNTTSLTDFPMSYFVDTSENMP
CCEECCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHEEECCCCCC
FTEVTQQTFIDSSNRVSLGTAAIKTWAKIPLVNTSNSPQTLYLHHPYAYHNRQVGLYETV
HHHHHHHHHCCCCCCEEEHHHHHHHHHHCEEEECCCCCCEEEEECCCHHCCCCCCEEECC
DGQETLRRILDLDDPSTYGWLYGGAAVFEVTLAPHQKKTLYVESVSFSHQWFSIDLYNKE
CHHHHHHHHHCCCCCCCCCEEECCEEEEEEEECCCCCCEEEEEEEECCCEEEEEEEECCC
QSQRALLGSFTDIAVMVGMLLALIIYNLLLFMYSRQRDNLFYACYLISGGIWIALSYGLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEHHHHH
AEVFAFYGSASLYWHLTLMTMPIFLILFMMDIFETRQHYRFEHYALVFVLVLLVAEFCYG
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVDIIGALRYSSSLAALMMLTTLSVTISLVIKRHPIAKYFLLGHCLFVGFSGLAVMFYKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEEEEEC
RAEFSYLSSHGVGVGIMLEALVLALIIAYRIRLLEEIKASQEELKYQAATDSLTHLFNRR
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
HFHKEAQRIYMQASVTQQPMAVIICDIDLFKRVNDKYGHLMGDQVIIDIATTLKQHARKC
HHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHCHHHCHHCCCHHHHHHHHHHHHHHHHC
DIVARYGGEEFIMLLHDVSLTEAHQCAERIRSAVAELSFMAETQEAFTVTLSLGVAAVDF
CHHEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEEEHHHHHHHH
VHPLEHAIKLADDALYRAKHQGRNNVQSSEINLLEIKEGIN
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCC
>Mature Secondary Structure
MRICMGRATWMGLLTLGALLLICVAFTTKAATAEISWQDNTTSLTDFPMSYFVDTSENMP
CCEECCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHEEECCCCCC
FTEVTQQTFIDSSNRVSLGTAAIKTWAKIPLVNTSNSPQTLYLHHPYAYHNRQVGLYETV
HHHHHHHHHCCCCCCEEEHHHHHHHHHHCEEEECCCCCCEEEEECCCHHCCCCCCEEECC
DGQETLRRILDLDDPSTYGWLYGGAAVFEVTLAPHQKKTLYVESVSFSHQWFSIDLYNKE
CHHHHHHHHHCCCCCCCCCEEECCEEEEEEEECCCCCCEEEEEEEECCCEEEEEEEECCC
QSQRALLGSFTDIAVMVGMLLALIIYNLLLFMYSRQRDNLFYACYLISGGIWIALSYGLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEHHHHH
AEVFAFYGSASLYWHLTLMTMPIFLILFMMDIFETRQHYRFEHYALVFVLVLLVAEFCYG
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVDIIGALRYSSSLAALMMLTTLSVTISLVIKRHPIAKYFLLGHCLFVGFSGLAVMFYKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEEEEEC
RAEFSYLSSHGVGVGIMLEALVLALIIAYRIRLLEEIKASQEELKYQAATDSLTHLFNRR
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
HFHKEAQRIYMQASVTQQPMAVIICDIDLFKRVNDKYGHLMGDQVIIDIATTLKQHARKC
HHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHCHHHCHHCCCHHHHHHHHHHHHHHHHC
DIVARYGGEEFIMLLHDVSLTEAHQCAERIRSAVAELSFMAETQEAFTVTLSLGVAAVDF
CHHEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEEEHHHHHHHH
VHPLEHAIKLADDALYRAKHQGRNNVQSSEINLLEIKEGIN
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]