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The map label for this gene is cpxA [H]

Identifier: 117918709

GI number: 117918709

Start: 283974

End: 285323

Strand: Reverse

Name: cpxA [H]

Synonym: Shewana3_0252

Alternate gene names: 117918709

Gene position: 285323-283974 (Counterclockwise)

Preceding gene: 117918710

Following gene: 117918707

Centisome position: 5.74

GC content: 51.41

Gene sequence:

>1350_bases
GTGCCTAATCGCTTATTTATCAAGTTACTACTCGGATTTTGGATCTGTAGCTCGCTGATTATCGCTTTGGTCGGCCTGCT
GCCATTGCTGCAGCAAAATCATGACCGCGCCCCAATTCCGCCGCATCTGCAAAAGGTGTTGGCAAGCATAGCGCAGCGTA
TTCAAGACAATCCCGAGCTAGTCACATCTGATTTTCTGCGCCGCTGGGAAAGACGTGGCGATATGGAAGGCAAACCCCTT
AGGCTCTATCTGGCCAACAGCCAAGGCCAAGTGATTAATACCAGCCGAGTGAGCCGCGGTGTACGCAGCTTTATGCTGAT
GACCGACGAGGAAAAACAGCCGATTAGTCATCAATTTAAAGATGAATTGGTCTTCGGCCCACACCAATTTACCCTTCAGG
GTGAAACCTATTATCTCTATGGCCGCTTGCCGGATATTCACCCTCGCCCCTGGTTCTTCTTCTTTATCGAAAATAAGCTG
CTCACCCTAAGCCTAGCCATAGTGCTCTCGGGATTACTGTGCGCCATACTCGCTTGGCATTTAGGTAAACCATTAAACTC
GCTCAAGAAAAGTGCCGATGCCCTCGCCGAAGGTGATCTCAGCAATCGCGTCGATAAGGCGACCACTCAACGTAACGATG
AAATCGGCCAGCTCGCCACCGCCTTTAATAGCATGGCGGATTCGATCGAAGCCATGGTGAAGAATCAGCAACGTTTGATG
GGGGATATTTCCCACGAACTGCGCACCCCACTGACCCGCCTACAATTATCACTGGCATTGGCCCGCAAGAAAGGCCAACA
GACTACGGAAACCGACCGTATCGCCTATGAGGCCGAGCAACTAGAGAAATTGATCGCAGAGCTCTTGGAGTTGTCGCGGG
TCAAACTCAGCACCAATGAGACTAAGGTGCGCCTCGGATTGGCCGAGTCTCTCAGTCAAGTGCTTGATGACGCTGAATTT
GAGGCCGATCAACAGGGTAAAAAGATCACTATCGATATCGATGAAGCCATCGAGCTCAGCCATTATCCGAAATCCCTGTC
CCGTGCGATAGAAAACCTGCTGCGCAACGCGATTCGTTATGCCCAGAGCGATATTCATCTGCTCGCGAGCCAAGCCAACG
GCCAAGTACAGATCACCATTAAAGACGATGGTCCAGGGATTGATCCTGCTGAGCTTGAGGCAATTTTCAAACCCTTCTAT
CGCCCCGATTCGGCAAGACAGCGAGAAAGCGGTGGCTGGGGCCTAGGACTCGCCATTACCGAAGCAGCCATTAGCGCCCA
TAAAGGTAAAATCAGGGCCGAGAATCGCCAGCCCCACGGCCTTGAAGTCAATATCAGTTTACCAACCTAA

Upstream 100 bases:

>100_bases
ATCTACGCAAAAAACTCCCCGAGCGAAGCGACGGCAGACCTAGGGTGAAAACCATCCGTGGCAAAGGCTATATCTGGCTA
CCATAACGGCGGGAACAACT

Downstream 100 bases:

>100_bases
AAACATAAGGCTCGCTAACACAGTTAGCGGGGCTTATATCATCAACAGTCAACTGCCGTTAATCCTTAATCCCTAGCTGT
TTTAACTTGCGATACAAGGC

Product: ATPase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MPNRLFIKLLLGFWICSSLIIALVGLLPLLQQNHDRAPIPPHLQKVLASIAQRIQDNPELVTSDFLRRWERRGDMEGKPL
RLYLANSQGQVINTSRVSRGVRSFMLMTDEEKQPISHQFKDELVFGPHQFTLQGETYYLYGRLPDIHPRPWFFFFIENKL
LTLSLAIVLSGLLCAILAWHLGKPLNSLKKSADALAEGDLSNRVDKATTQRNDEIGQLATAFNSMADSIEAMVKNQQRLM
GDISHELRTPLTRLQLSLALARKKGQQTTETDRIAYEAEQLEKLIAELLELSRVKLSTNETKVRLGLAESLSQVLDDAEF
EADQQGKKITIDIDEAIELSHYPKSLSRAIENLLRNAIRYAQSDIHLLASQANGQVQITIKDDGPGIDPAELEAIFKPFY
RPDSARQRESGGWGLGLAITEAAISAHKGKIRAENRQPHGLEVNISLPT

Sequences:

>Translated_449_residues
MPNRLFIKLLLGFWICSSLIIALVGLLPLLQQNHDRAPIPPHLQKVLASIAQRIQDNPELVTSDFLRRWERRGDMEGKPL
RLYLANSQGQVINTSRVSRGVRSFMLMTDEEKQPISHQFKDELVFGPHQFTLQGETYYLYGRLPDIHPRPWFFFFIENKL
LTLSLAIVLSGLLCAILAWHLGKPLNSLKKSADALAEGDLSNRVDKATTQRNDEIGQLATAFNSMADSIEAMVKNQQRLM
GDISHELRTPLTRLQLSLALARKKGQQTTETDRIAYEAEQLEKLIAELLELSRVKLSTNETKVRLGLAESLSQVLDDAEF
EADQQGKKITIDIDEAIELSHYPKSLSRAIENLLRNAIRYAQSDIHLLASQANGQVQITIKDDGPGIDPAELEAIFKPFY
RPDSARQRESGGWGLGLAITEAAISAHKGKIRAENRQPHGLEVNISLPT
>Mature_448_residues
PNRLFIKLLLGFWICSSLIIALVGLLPLLQQNHDRAPIPPHLQKVLASIAQRIQDNPELVTSDFLRRWERRGDMEGKPLR
LYLANSQGQVINTSRVSRGVRSFMLMTDEEKQPISHQFKDELVFGPHQFTLQGETYYLYGRLPDIHPRPWFFFFIENKLL
TLSLAIVLSGLLCAILAWHLGKPLNSLKKSADALAEGDLSNRVDKATTQRNDEIGQLATAFNSMADSIEAMVKNQQRLMG
DISHELRTPLTRLQLSLALARKKGQQTTETDRIAYEAEQLEKLIAELLELSRVKLSTNETKVRLGLAESLSQVLDDAEFE
ADQQGKKITIDIDEAIELSHYPKSLSRAIENLLRNAIRYAQSDIHLLASQANGQVQITIKDDGPGIDPAELEAIFKPFYR
PDSARQRESGGWGLGLAITEAAISAHKGKIRAENRQPHGLEVNISLPT

Specific function: This protein is involved in several diverse cellular processes, such as the functioning of acetohydroxyacid synthetase I, in the biosynthesis of isoleucine and valine, the TraJ protein activation activity for tra gene expression in F plasmid, and the synt

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790346, Length=372, Percent_Identity=38.1720430107527, Blast_Score=213, Evalue=1e-56,
Organism=Escherichia coli, GI1787894, Length=332, Percent_Identity=29.8192771084337, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786783, Length=303, Percent_Identity=31.023102310231, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1788393, Length=273, Percent_Identity=32.6007326007326, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1789808, Length=294, Percent_Identity=28.2312925170068, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1786600, Length=220, Percent_Identity=27.7272727272727, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI145693157, Length=242, Percent_Identity=27.6859504132231, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786912, Length=219, Percent_Identity=31.5068493150685, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790551, Length=277, Percent_Identity=27.0758122743682, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788279, Length=302, Percent_Identity=28.476821192053, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787374, Length=289, Percent_Identity=25.9515570934256, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1790436, Length=218, Percent_Identity=27.9816513761468, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789403, Length=289, Percent_Identity=28.0276816608997, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1789149, Length=336, Percent_Identity=23.5119047619048, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1788549, Length=224, Percent_Identity=27.6785714285714, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87082128, Length=315, Percent_Identity=23.8095238095238, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788713, Length=256, Percent_Identity=25.390625, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87081816, Length=331, Percent_Identity=25.9818731117825, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50431; Mature: 50299

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNRLFIKLLLGFWICSSLIIALVGLLPLLQQNHDRAPIPPHLQKVLASIAQRIQDNPEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHH
VTSDFLRRWERRGDMEGKPLRLYLANSQGQVINTSRVSRGVRSFMLMTDEEKQPISHQFK
HHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHCCCCCCCCHHHHHH
DELVFGPHQFTLQGETYYLYGRLPDIHPRPWFFFFIENKLLTLSLAIVLSGLLCAILAWH
HHHEECCCEEEEECCEEEEEECCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHH
LGKPLNSLKKSADALAEGDLSNRVDKATTQRNDEIGQLATAFNSMADSIEAMVKNQQRLM
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GDISHELRTPLTRLQLSLALARKKGQQTTETDRIAYEAEQLEKLIAELLELSRVKLSTNE
HHHHHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
TKVRLGLAESLSQVLDDAEFEADQQGKKITIDIDEAIELSHYPKSLSRAIENLLRNAIRY
HHEEECHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AQSDIHLLASQANGQVQITIKDDGPGIDPAELEAIFKPFYRPDSARQRESGGWGLGLAIT
HHHHHHHHEECCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHCCCCCEEHHHHH
EAAISAHKGKIRAENRQPHGLEVNISLPT
HHHHHHHCCCEEECCCCCCCEEEEEECCC
>Mature Secondary Structure 
PNRLFIKLLLGFWICSSLIIALVGLLPLLQQNHDRAPIPPHLQKVLASIAQRIQDNPEL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHH
VTSDFLRRWERRGDMEGKPLRLYLANSQGQVINTSRVSRGVRSFMLMTDEEKQPISHQFK
HHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHCCCCCCCCHHHHHH
DELVFGPHQFTLQGETYYLYGRLPDIHPRPWFFFFIENKLLTLSLAIVLSGLLCAILAWH
HHHEECCCEEEEECCEEEEEECCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHH
LGKPLNSLKKSADALAEGDLSNRVDKATTQRNDEIGQLATAFNSMADSIEAMVKNQQRLM
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GDISHELRTPLTRLQLSLALARKKGQQTTETDRIAYEAEQLEKLIAELLELSRVKLSTNE
HHHHHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
TKVRLGLAESLSQVLDDAEFEADQQGKKITIDIDEAIELSHYPKSLSRAIENLLRNAIRY
HHEEECHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AQSDIHLLASQANGQVQITIKDDGPGIDPAELEAIFKPFYRPDSARQRESGGWGLGLAIT
HHHHHHHHEECCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHCCCCCEEHHHHH
EAAISAHKGKIRAENRQPHGLEVNISLPT
HHHHHHHCCCEEECCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]