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The map label for this gene is trkH [H]

Identifier: 117918486

GI number: 117918486

Start: 34058

End: 35515

Strand: Direct

Name: trkH [H]

Synonym: Shewana3_0027

Alternate gene names: 117918486

Gene position: 34058-35515 (Clockwise)

Preceding gene: 117918485

Following gene: 117918487

Centisome position: 0.68

GC content: 50.34

Gene sequence:

>1458_bases
ATGCAATACAAAACCATAATAAGAATCATAGGTCTACTTATCGGCCTGTTCTCCATCACTATGCTGCCGCCAGCCTTAAT
CGCCATTTGGTATAACGATGGCGGTGGTACTGCGTTTATTCAGGCATTTTTTGTCAGCTTATTTATCGGTTTTTGGCTCT
GGTATCCTAATCGTCGCTGCAAAGAGGAATTGCGAACCCGTGAGGGGTTTCTGATTGTGGTCCTGTTCTGGACCGTTCTT
GGCTCCATCGGTGCTTTACCTTTTATCTTCTCAAGCCAGCCCGATCTCAGCTGGACCGACAGTTTTTTCGAATCATTTTC
CGCACTGACCACCACGGGAGCCACAGTTATTGTCGGACTGGACTCCTTGCCTAAGGCCATTCTGTTTTATCGACATATGC
TGCAATGGCTCGGCGGTATGGGGATCATCGTTTTAGCCGTGGCGATTCTGCCTGTGCTGGGCGTTGGGGGCATGCAGCTG
TATCGCGCCGAGATTCCTGGCCCTGTGAAGGACAGTAAGATGACGCCGAGGATTGCCGAAACGGCCAAGGCGTTATGGTA
CATCTATCTATTGCTAACCATTGCCTGTGCTGGCGCTTATTGGCTGGCGGGAATGAGCGTTTTCGATGCCGTGTGTCACT
CGTTTTCGACCATCGCTATCGGGGGCTTTTCGACCCACGATGCCAGTATGGGATACTTCGACAGCTCAGTGATCAACCTG
ATTTGCGTGTTCTTTTTGATTGTCTCTGCGGTGAACTTTAGCGTGCACTTTGCGGCATTTTCGCGTCGCGGGATCAATTT
TAGAGTCTATTTTCGAGATACCGAGTTCAAAATGCTGGTGGCGATTCAGTTGGTGCTGACGGCGATTTGCTTCTTAACCC
TTTATCACTCAGGGATTTATGACTCGCCAGAAGAAACCTTAGATCACGCCTTATTCCAAGCGGTTTCGGTGGCGACAACC
GCCGGCTTTGGTACCGAAAGCTTCCATATGTGGCCGCTGTTCCTGCCGATTCTGTTGATCTTCTCAAGCTTTATCGGTGG
TTGTGGTGGTTCAACTGCGGGCGGGATTAAGGTGATCCGGGTTATCCTGCTGCTGTTACAAGGTTCACGCGAACTTAAAC
GCCTTGTTCACCCTAAGGCGATGTTCTCGATTCGTATCGGCTCCAAGGCATTACCTGACCGGGTTGTCGATGCCGTGTGG
GGATTTTTCTCCGCCTATGCCTTAGTCTTCGTGCTGTGTATGTTAGCGCTGATGGCTATGGGGCTAGATGATATTACCGC
CTTTAGTGCCACGGCGGCCTGCTTAAATAACCTCGGTCCGGGTCTTGGGGAAGTAGCAAGTAACTACGCCAGTATTGGTG
ATGGTGCTAAATGGGTGCTGGTGGTAGCCATGTTATTTGGCCGCCTCGAAGTCTTTACCTTGCTGATTTTGTTCACGCCA
ACTTTCTGGAGGGATTAA

Upstream 100 bases:

>100_bases
TGCGCGCAGAGTTTGAGCTGTGATGCCCGCGTAAATTATGCCAAAATATGCAAAATGCTGAAAATACCTTTGCAGCCAAT
GGAATAATTGAACACGCGGA

Downstream 100 bases:

>100_bases
CATGCAGACACTAATCATCTATTCGACAATTGATGGCCAAACACTGGAAATCTGCCGCAAAATCAAAACGCTTGCCGAAC
AAGCGGGTGAGCAGGTGTCT

Product: TrkH family potassium uptake protein

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MQYKTIIRIIGLLIGLFSITMLPPALIAIWYNDGGGTAFIQAFFVSLFIGFWLWYPNRRCKEELRTREGFLIVVLFWTVL
GSIGALPFIFSSQPDLSWTDSFFESFSALTTTGATVIVGLDSLPKAILFYRHMLQWLGGMGIIVLAVAILPVLGVGGMQL
YRAEIPGPVKDSKMTPRIAETAKALWYIYLLLTIACAGAYWLAGMSVFDAVCHSFSTIAIGGFSTHDASMGYFDSSVINL
ICVFFLIVSAVNFSVHFAAFSRRGINFRVYFRDTEFKMLVAIQLVLTAICFLTLYHSGIYDSPEETLDHALFQAVSVATT
AGFGTESFHMWPLFLPILLIFSSFIGGCGGSTAGGIKVIRVILLLLQGSRELKRLVHPKAMFSIRIGSKALPDRVVDAVW
GFFSAYALVFVLCMLALMAMGLDDITAFSATAACLNNLGPGLGEVASNYASIGDGAKWVLVVAMLFGRLEVFTLLILFTP
TFWRD

Sequences:

>Translated_485_residues
MQYKTIIRIIGLLIGLFSITMLPPALIAIWYNDGGGTAFIQAFFVSLFIGFWLWYPNRRCKEELRTREGFLIVVLFWTVL
GSIGALPFIFSSQPDLSWTDSFFESFSALTTTGATVIVGLDSLPKAILFYRHMLQWLGGMGIIVLAVAILPVLGVGGMQL
YRAEIPGPVKDSKMTPRIAETAKALWYIYLLLTIACAGAYWLAGMSVFDAVCHSFSTIAIGGFSTHDASMGYFDSSVINL
ICVFFLIVSAVNFSVHFAAFSRRGINFRVYFRDTEFKMLVAIQLVLTAICFLTLYHSGIYDSPEETLDHALFQAVSVATT
AGFGTESFHMWPLFLPILLIFSSFIGGCGGSTAGGIKVIRVILLLLQGSRELKRLVHPKAMFSIRIGSKALPDRVVDAVW
GFFSAYALVFVLCMLALMAMGLDDITAFSATAACLNNLGPGLGEVASNYASIGDGAKWVLVVAMLFGRLEVFTLLILFTP
TFWRD
>Mature_485_residues
MQYKTIIRIIGLLIGLFSITMLPPALIAIWYNDGGGTAFIQAFFVSLFIGFWLWYPNRRCKEELRTREGFLIVVLFWTVL
GSIGALPFIFSSQPDLSWTDSFFESFSALTTTGATVIVGLDSLPKAILFYRHMLQWLGGMGIIVLAVAILPVLGVGGMQL
YRAEIPGPVKDSKMTPRIAETAKALWYIYLLLTIACAGAYWLAGMSVFDAVCHSFSTIAIGGFSTHDASMGYFDSSVINL
ICVFFLIVSAVNFSVHFAAFSRRGINFRVYFRDTEFKMLVAIQLVLTAICFLTLYHSGIYDSPEETLDHALFQAVSVATT
AGFGTESFHMWPLFLPILLIFSSFIGGCGGSTAGGIKVIRVILLLLQGSRELKRLVHPKAMFSIRIGSKALPDRVVDAVW
GFFSAYALVFVLCMLALMAMGLDDITAFSATAACLNNLGPGLGEVASNYASIGDGAKWVLVVAMLFGRLEVFTLLILFTP
TFWRD

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=485, Percent_Identity=65.5670103092783, Blast_Score=623, Evalue=1e-180,
Organism=Escherichia coli, GI1787626, Length=484, Percent_Identity=42.1487603305785, Blast_Score=411, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 53278; Mature: 53278

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: PS00778 HIS_ACID_PHOSPHAT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYKTIIRIIGLLIGLFSITMLPPALIAIWYNDGGGTAFIQAFFVSLFIGFWLWYPNRRC
CCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHH
KEELRTREGFLIVVLFWTVLGSIGALPFIFSSQPDLSWTDSFFESFSALTTTGATVIVGL
HHHHHHCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEC
DSLPKAILFYRHMLQWLGGMGIIVLAVAILPVLGVGGMQLYRAEIPGPVKDSKMTPRIAE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHEECCCCCCCCCCCCCCCHHHH
TAKALWYIYLLLTIACAGAYWLAGMSVFDAVCHSFSTIAIGGFSTHDASMGYFDSSVINL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHH
ICVFFLIVSAVNFSVHFAAFSRRGINFRVYFRDTEFKMLVAIQLVLTAICFLTLYHSGIY
HHHHHHHHHHHHHHHEEHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCC
DSPEETLDHALFQAVSVATTAGFGTESFHMWPLFLPILLIFSSFIGGCGGSTAGGIKVIR
CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
VILLLLQGSRELKRLVHPKAMFSIRIGSKALPDRVVDAVWGFFSAYALVFVLCMLALMAM
HHHHHHCCCHHHHHHHCCHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLDDITAFSATAACLNNLGPGLGEVASNYASIGDGAKWVLVVAMLFGRLEVFTLLILFTP
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
TFWRD
HHCCC
>Mature Secondary Structure
MQYKTIIRIIGLLIGLFSITMLPPALIAIWYNDGGGTAFIQAFFVSLFIGFWLWYPNRRC
CCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHH
KEELRTREGFLIVVLFWTVLGSIGALPFIFSSQPDLSWTDSFFESFSALTTTGATVIVGL
HHHHHHCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEC
DSLPKAILFYRHMLQWLGGMGIIVLAVAILPVLGVGGMQLYRAEIPGPVKDSKMTPRIAE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHEECCCCCCCCCCCCCCCHHHH
TAKALWYIYLLLTIACAGAYWLAGMSVFDAVCHSFSTIAIGGFSTHDASMGYFDSSVINL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHH
ICVFFLIVSAVNFSVHFAAFSRRGINFRVYFRDTEFKMLVAIQLVLTAICFLTLYHSGIY
HHHHHHHHHHHHHHHEEHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCC
DSPEETLDHALFQAVSVATTAGFGTESFHMWPLFLPILLIFSSFIGGCGGSTAGGIKVIR
CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
VILLLLQGSRELKRLVHPKAMFSIRIGSKALPDRVVDAVWGFFSAYALVFVLCMLALMAM
HHHHHHCCCHHHHHHHCCHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLDDITAFSATAACLNNLGPGLGEVASNYASIGDGAKWVLVVAMLFGRLEVFTLLILFTP
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
TFWRD
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]