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The map label for this gene is recU [H]

Identifier: 116873326

GI number: 116873326

Start: 1939430

End: 1940035

Strand: Direct

Name: recU [H]

Synonym: lwe1910

Alternate gene names: 116873326

Gene position: 1939430-1940035 (Clockwise)

Preceding gene: 116873315

Following gene: 116873327

Centisome position: 68.92

GC content: 36.47

Gene sequence:

>606_bases
ATGGCTATTGGCTATCCTAACGGCAAGAAGTATGCAGCGAGTCACGAGGGAATTCCGCAAAAAAAACGGAAAGCTCCTGT
TACTTATGGAAAACGTGGTATGTCTTTGGAAGATGACTTAAATGATACAATAGCTTATTACCTAGCTCAAGATATCGCCG
TCATTCATAAAAAACCTACCCCAGTCCAAATTGTCAGTGTGGATTATCCAAAAAGAAGTAGTGCAAAAATTAAGGAAGCC
TATTTCAAAACACCATCCACGACAGACTATAATGGTGTATACAAAGGAAAGTATATTGATTTTGAAGCAAAAGAAACGCA
AAATACTACCTCCTTTCCATTAAGTAATTTTCACGACCACCAAATGATTCATATGGCAAATGTGTTAAAACAAGATGGCA
TTGTTTTTGTCATTATTGCCTTCCAAAAAATCGGTGAAACTTATTTCATTCCCTTTGAAAAGTTTTATCCATTTTGGCAA
AGAATGCAAAGCGGCGGCAGAAAATCCGTCACTATTGCAGAAATACAAGATGTATCAGACCAAATTCCTTATGGTCTAAA
TCCAAGGCTTGACTTCTTGAAATCAATCGAGAAATTATACTTCTAG

Upstream 100 bases:

>100_bases
TATTTTGCATTTATTTACTACTATCATTTTCATTTTTATTTGTTATAATAGATGATAGTCTAAAATTCAGAATAGAAATT
TTCTGATTGAGGTGAAAAAA

Downstream 100 bases:

>100_bases
TCAGCTTTTTTAAAGGAGAGAGATTTTTAATGGCAGATAAACCGCAGACAAGATCTCAGTATCGCAGCAAAAAAAATGGA
AATTCTAAAAAGAATCCATC

Product: Holliday junction-specific endonuclease

Products: NA

Alternate protein names: Recombination protein U homolog [H]

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MAIGYPNGKKYAASHEGIPQKKRKAPVTYGKRGMSLEDDLNDTIAYYLAQDIAVIHKKPTPVQIVSVDYPKRSSAKIKEA
YFKTPSTTDYNGVYKGKYIDFEAKETQNTTSFPLSNFHDHQMIHMANVLKQDGIVFVIIAFQKIGETYFIPFEKFYPFWQ
RMQSGGRKSVTIAEIQDVSDQIPYGLNPRLDFLKSIEKLYF

Sequences:

>Translated_201_residues
MAIGYPNGKKYAASHEGIPQKKRKAPVTYGKRGMSLEDDLNDTIAYYLAQDIAVIHKKPTPVQIVSVDYPKRSSAKIKEA
YFKTPSTTDYNGVYKGKYIDFEAKETQNTTSFPLSNFHDHQMIHMANVLKQDGIVFVIIAFQKIGETYFIPFEKFYPFWQ
RMQSGGRKSVTIAEIQDVSDQIPYGLNPRLDFLKSIEKLYF
>Mature_200_residues
AIGYPNGKKYAASHEGIPQKKRKAPVTYGKRGMSLEDDLNDTIAYYLAQDIAVIHKKPTPVQIVSVDYPKRSSAKIKEAY
FKTPSTTDYNGVYKGKYIDFEAKETQNTTSFPLSNFHDHQMIHMANVLKQDGIVFVIIAFQKIGETYFIPFEKFYPFWQR
MQSGGRKSVTIAEIQDVSDQIPYGLNPRLDFLKSIEKLYF

Specific function: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair

COG id: COG3331

COG function: function code R; Penicillin-binding protein-related factor A, putative recombinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recU family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004612
- InterPro:   IPR011335 [H]

Pfam domain/function: PF03838 RecU [H]

EC number: NA

Molecular weight: Translated: 23054; Mature: 22922

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIGYPNGKKYAASHEGIPQKKRKAPVTYGKRGMSLEDDLNDTIAYYLAQDIAVIHKKPT
CCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCC
PVQIVSVDYPKRSSAKIKEAYFKTPSTTDYNGVYKGKYIDFEAKETQNTTSFPLSNFHDH
CEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCEECCEEEECCCCCCCCCCCCCCCCCCCH
QMIHMANVLKQDGIVFVIIAFQKIGETYFIPFEKFYPFWQRMQSGGRKSVTIAEIQDVSD
HHHHHHHHHHCCCEEEEEEEEHHHCCEEEECHHHHHHHHHHHHCCCCCEEEHHHHHHHHH
QIPYGLNPRLDFLKSIEKLYF
CCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
AIGYPNGKKYAASHEGIPQKKRKAPVTYGKRGMSLEDDLNDTIAYYLAQDIAVIHKKPT
CCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCC
PVQIVSVDYPKRSSAKIKEAYFKTPSTTDYNGVYKGKYIDFEAKETQNTTSFPLSNFHDH
CEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCEECCEEEECCCCCCCCCCCCCCCCCCCH
QMIHMANVLKQDGIVFVIIAFQKIGETYFIPFEKFYPFWQRMQSGGRKSVTIAEIQDVSD
HHHHHHHHHHCCCEEEEEEEEHHHCCEEEECHHHHHHHHHHHHCCCCCEEEHHHHHHHHH
QIPYGLNPRLDFLKSIEKLYF
CCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]