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The map label for this gene is ccpN [H]

Identifier: 116873300

GI number: 116873300

Start: 1912497

End: 1913126

Strand: Direct

Name: ccpN [H]

Synonym: lwe1884

Alternate gene names: 116873300

Gene position: 1912497-1913126 (Clockwise)

Preceding gene: 116873299

Following gene: 116873301

Centisome position: 67.96

GC content: 37.78

Gene sequence:

>630_bases
GTGATTCCCATCGAACTTTCCCCTAGACAACATCAAATTGTTGCCTATGTACGCGCGAATGAGCCAGCTACTGGTGACTC
CATTGCCGCCCATTTAAAACTAACACGAGCCACCATACGAGCTGACTTATCCATTTTAACAATGACTGGAATTTTAGATG
CCCGCCCTAAAGTTGGCTACTTCTATTCTGGTTTAGAAACAAATCCTATTCATTTTGATGAAATCCGTCAATTAAAAATT
TCTGAAATTATGACACAACCTTTTTTCGCAAAAAAAGAAACAAGTGTTTATGACGCTATTGTAATGCTCTTTATGGAAGA
TATTGGTAGTTTATACGTTATTGATGAAGAGGAATTAGTTGGTCTTGTCTCCAGAAAGGATTTACTTAAAGGAGCACTTG
CAGATGCTGACACAAAGGCTACTCCTATAGCGACAATTATGACGCGCATGCCAAACCTTGTTACTGTCGCTAAAAATGAC
ACTGTCTTGCACGCCGCAGAACAACTCGTTTTTCATCAAATTGATTCCCTTCCTGTGCTTGAAAATAAATCTGGTAAAGC
AAAAGTCATCGGGAAAATATCAAAAACACGTATTACTGCATTATTTGTTGATACAATAAAAAAGGTTTAA

Upstream 100 bases:

>100_bases
TTCTCATTATTGAGAAGGTTTTTATATAGTATGACATAATTGAGGCTTGTTTTTAATTATGTCATACTATATAATAATTA
GCATAACATAATAAAAGGAT

Downstream 100 bases:

>100_bases
TAGGAGGAACATATGGAAAAATCGGTTATTATATACGTTATTTCAGATGCTATCGGAGAAACTGCTCAACATATTATTCG
CGCGGTAACGGCACAGTTTT

Product: CBS domain-containing protein

Products: NA

Alternate protein names: Catabolite control protein N; Control catabolite protein of gluconeogenesis [H]

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MIPIELSPRQHQIVAYVRANEPATGDSIAAHLKLTRATIRADLSILTMTGILDARPKVGYFYSGLETNPIHFDEIRQLKI
SEIMTQPFFAKKETSVYDAIVMLFMEDIGSLYVIDEEELVGLVSRKDLLKGALADADTKATPIATIMTRMPNLVTVAKND
TVLHAAEQLVFHQIDSLPVLENKSGKAKVIGKISKTRITALFVDTIKKV

Sequences:

>Translated_209_residues
MIPIELSPRQHQIVAYVRANEPATGDSIAAHLKLTRATIRADLSILTMTGILDARPKVGYFYSGLETNPIHFDEIRQLKI
SEIMTQPFFAKKETSVYDAIVMLFMEDIGSLYVIDEEELVGLVSRKDLLKGALADADTKATPIATIMTRMPNLVTVAKND
TVLHAAEQLVFHQIDSLPVLENKSGKAKVIGKISKTRITALFVDTIKKV
>Mature_209_residues
MIPIELSPRQHQIVAYVRANEPATGDSIAAHLKLTRATIRADLSILTMTGILDARPKVGYFYSGLETNPIHFDEIRQLKI
SEIMTQPFFAKKETSVYDAIVMLFMEDIGSLYVIDEEELVGLVSRKDLLKGALADADTKATPIATIMTRMPNLVTVAKND
TVLHAAEQLVFHQIDSLPVLENKSGKAKVIGKISKTRITALFVDTIKKV

Specific function: Transcription repressor that binds to the promoter of gapB and pckA genes, preventing their expression. Acts as a regulator for catabolite repression of gluconeogenic genes [H]

COG id: COG0517

COG function: function code R; FOG: CBS domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000644
- InterPro:   IPR013196
- InterPro:   IPR001034
- InterPro:   IPR016842
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00571 CBS; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 23134; Mature: 23134

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS00894 HTH_DEOR_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPIELSPRQHQIVAYVRANEPATGDSIAAHLKLTRATIRADLSILTMTGILDARPKVGY
CCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECHHCCCCCCCE
FYSGLETNPIHFDEIRQLKISEIMTQPFFAKKETSVYDAIVMLFMEDIGSLYVIDEEELV
EECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECHHHHH
GLVSRKDLLKGALADADTKATPIATIMTRMPNLVTVAKNDTVLHAAEQLVFHQIDSLPVL
HHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCE
ENKSGKAKVIGKISKTRITALFVDTIKKV
ECCCCCEEEEECHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIPIELSPRQHQIVAYVRANEPATGDSIAAHLKLTRATIRADLSILTMTGILDARPKVGY
CCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECHHCCCCCCCE
FYSGLETNPIHFDEIRQLKISEIMTQPFFAKKETSVYDAIVMLFMEDIGSLYVIDEEELV
EECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECHHHHH
GLVSRKDLLKGALADADTKATPIATIMTRMPNLVTVAKNDTVLHAAEQLVFHQIDSLPVL
HHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCE
ENKSGKAKVIGKISKTRITALFVDTIKKV
ECCCCCEEEEECHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]