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The map label for this gene is yocR [H]

Identifier: 116873195

GI number: 116873195

Start: 1807815

End: 1809170

Strand: Direct

Name: yocR [H]

Synonym: lwe1779

Alternate gene names: 116873195

Gene position: 1807815-1809170 (Clockwise)

Preceding gene: 116873194

Following gene: 116873212

Centisome position: 64.24

GC content: 38.57

Gene sequence:

>1356_bases
ATGCAAGAAAACAGAGAAGAATGGGGCTCAAAAATCGGATTTATTTTAGCATCCGCTGGGTCTGCAATAGGTATCGGTGC
GATTTGGAAACTGCCTTATGTGGCTGCAACTGCAGGAGGTGGCGCATTTTTCCTATTGTTTTTAGTTTTGACTTTACTCG
TTGTTATGCCACTTTTGATTGCCGAATTTGTCATTGGGCGTGGTTCAGGCGGAGATGCTGTTCAAGCTTATAAAACGCTC
GCTCCTTTGACAAAGTGGAATCTCCTTGGAAAATTAGGTGTCGTTGGCGCAAGTATTTTATTTTCGTTCTATAGTGTAGT
TGGTGGTTGGATAATCACTTACTTAATAAAAACATTAGTTGGTGGTATCGCTGGAGAAAACCAAGCGAGTCTGCTACATG
ATTTTCAAGTGACGACAGCGAATCCATGGATATCTGTCGGTGCAACGATTCTCTTTATTTTACTTAATGTGATTGTCATT
AGCCGCGGGGTTGTTAGCGGGATTGAAAAAATGAGTAAGTTTATGATGCCAGCTCTTTTTATATTATTTATTGTTTTGAT
AATCCGGTCCTTGACGCTTCCTGGGGCAATGGAGGGAGTAGCCTTTTTCTTACGACCAGATTTTAGCCATTTTACTGCTC
AAACCGTCCTTATAACACTTGGTCAGGCATTCTTTTCCTTAAGTGTGGGGATTTCTGTAATGGTGACATACAGTTCTTAT
TTGAATCGCTCGGTTAGTTTACCACAGTCAGCGATTTCGGTTTCACTAATGAATGTGTTTGTTTCACTCCTTGCTGGGTT
AGCAATTTTTCCAGCAGCTTTTTCGTTTAATATTACACCAGATGCAGGACCTGGATTGCTATTCGTTATTCTGCCATCCA
TTTTTAACCAAATGCCATTTGGAATGTTGTTCTTTATTATATTTTTGATTTTATTCTTATTCGCTGCTTTAACATCTAGT
TTCTCGATGCTTGAAGCGACAGTTGCGCCACTGATGAATGCTGGTGTAAATCGTAAAAAAGCAAGCCTCTTGATGGGACT
AGTGATCGTTATAATGGCTATCCCAAGTGCACTAAGTTTTGGCGTTTGGAGTGACGTTCAACTATTTGGACTGAGTATTT
TTGATGCTGCTGATTTTCTTGTATCAAATATTATTTTACCAGTAGGCGCCTTATTTATTGCGATTTTTGTTGGCTATAGA
CTACCACGCGAAATGCTTTTAAAAGAATTTACAACCAGTAGCCATTTTGGTAAAAAAATGTTTATTCTTTGGCTCTTTTT
AATTAAATATATTGCTCCCATTGCCATTATTTTTGTTTTTCTATCCGCAACTGGATTGATGGATTTCTTCTTTTAA

Upstream 100 bases:

>100_bases
GTTGTAGTTGGGATAGCTTTTATTTTATGGTATGATGAGGAAAATTTGATTTTATAATGACATCAGGGTTTTTACATAGA
AAAAAGGAAATGGGGATATT

Downstream 100 bases:

>100_bases
TGAAAAAAGCAATCACGCTAAATAATAAGCGGATTGCTTTTCTTATATTGCCATAAGGACGATACTAGCTACACAAATCA
GGATTCCACTAAGGCCAATT

Product: sodium/neurotransmitter symporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MQENREEWGSKIGFILASAGSAIGIGAIWKLPYVAATAGGGAFFLLFLVLTLLVVMPLLIAEFVIGRGSGGDAVQAYKTL
APLTKWNLLGKLGVVGASILFSFYSVVGGWIITYLIKTLVGGIAGENQASLLHDFQVTTANPWISVGATILFILLNVIVI
SRGVVSGIEKMSKFMMPALFILFIVLIIRSLTLPGAMEGVAFFLRPDFSHFTAQTVLITLGQAFFSLSVGISVMVTYSSY
LNRSVSLPQSAISVSLMNVFVSLLAGLAIFPAAFSFNITPDAGPGLLFVILPSIFNQMPFGMLFFIIFLILFLFAALTSS
FSMLEATVAPLMNAGVNRKKASLLMGLVIVIMAIPSALSFGVWSDVQLFGLSIFDAADFLVSNIILPVGALFIAIFVGYR
LPREMLLKEFTTSSHFGKKMFILWLFLIKYIAPIAIIFVFLSATGLMDFFF

Sequences:

>Translated_451_residues
MQENREEWGSKIGFILASAGSAIGIGAIWKLPYVAATAGGGAFFLLFLVLTLLVVMPLLIAEFVIGRGSGGDAVQAYKTL
APLTKWNLLGKLGVVGASILFSFYSVVGGWIITYLIKTLVGGIAGENQASLLHDFQVTTANPWISVGATILFILLNVIVI
SRGVVSGIEKMSKFMMPALFILFIVLIIRSLTLPGAMEGVAFFLRPDFSHFTAQTVLITLGQAFFSLSVGISVMVTYSSY
LNRSVSLPQSAISVSLMNVFVSLLAGLAIFPAAFSFNITPDAGPGLLFVILPSIFNQMPFGMLFFIIFLILFLFAALTSS
FSMLEATVAPLMNAGVNRKKASLLMGLVIVIMAIPSALSFGVWSDVQLFGLSIFDAADFLVSNIILPVGALFIAIFVGYR
LPREMLLKEFTTSSHFGKKMFILWLFLIKYIAPIAIIFVFLSATGLMDFFF
>Mature_451_residues
MQENREEWGSKIGFILASAGSAIGIGAIWKLPYVAATAGGGAFFLLFLVLTLLVVMPLLIAEFVIGRGSGGDAVQAYKTL
APLTKWNLLGKLGVVGASILFSFYSVVGGWIITYLIKTLVGGIAGENQASLLHDFQVTTANPWISVGATILFILLNVIVI
SRGVVSGIEKMSKFMMPALFILFIVLIIRSLTLPGAMEGVAFFLRPDFSHFTAQTVLITLGQAFFSLSVGISVMVTYSSY
LNRSVSLPQSAISVSLMNVFVSLLAGLAIFPAAFSFNITPDAGPGLLFVILPSIFNQMPFGMLFFIIFLILFLFAALTSS
FSMLEATVAPLMNAGVNRKKASLLMGLVIVIMAIPSALSFGVWSDVQLFGLSIFDAADFLVSNIILPVGALFIAIFVGYR
LPREMLLKEFTTSSHFGKKMFILWLFLIKYIAPIAIIFVFLSATGLMDFFF

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI4507043, Length=400, Percent_Identity=24.75, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI21361581, Length=403, Percent_Identity=26.5508684863524, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI197276623, Length=379, Percent_Identity=25.8575197889182, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI54607094, Length=379, Percent_Identity=25.8575197889182, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI171184408, Length=399, Percent_Identity=23.0576441102757, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI171184406, Length=399, Percent_Identity=23.0576441102757, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI171184404, Length=399, Percent_Identity=23.0576441102757, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI7657587, Length=487, Percent_Identity=22.9979466119097, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI134304856, Length=408, Percent_Identity=25.2450980392157, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI188528618, Length=405, Percent_Identity=23.4567901234568, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI4507041, Length=389, Percent_Identity=25.1928020565553, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI92859670, Length=529, Percent_Identity=21.7391304347826, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI289191351, Length=392, Percent_Identity=25.765306122449, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI4557046, Length=392, Percent_Identity=25.765306122449, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI289191377, Length=392, Percent_Identity=25.765306122449, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI51468073, Length=535, Percent_Identity=22.4299065420561, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI194018524, Length=327, Percent_Identity=27.217125382263, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI11181770, Length=299, Percent_Identity=26.0869565217391, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI33354281, Length=303, Percent_Identity=23.1023102310231, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI58219014, Length=303, Percent_Identity=26.7326732673267, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI5032097, Length=386, Percent_Identity=24.0932642487047, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI12408638, Length=278, Percent_Identity=23.3812949640288, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI300360519, Length=217, Percent_Identity=27.1889400921659, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI218563756, Length=378, Percent_Identity=24.3386243386243, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI197276625, Length=152, Percent_Identity=26.9736842105263, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI289191353, Length=198, Percent_Identity=28.7878787878788, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI21361693, Length=121, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25146584, Length=388, Percent_Identity=23.4536082474227, Blast_Score=105, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17554804, Length=345, Percent_Identity=23.768115942029, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI133952791, Length=217, Percent_Identity=29.0322580645161, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17555248, Length=179, Percent_Identity=28.4916201117318, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71998244, Length=295, Percent_Identity=26.7796610169492, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115534083, Length=442, Percent_Identity=22.8506787330317, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71995588, Length=199, Percent_Identity=24.6231155778894, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17542050, Length=125, Percent_Identity=28.8, Blast_Score=65, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17535731, Length=123, Percent_Identity=30.8943089430894, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI17136952, Length=431, Percent_Identity=24.5939675174014, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI281364394, Length=378, Percent_Identity=25.6613756613757, Blast_Score=131, Evalue=9e-31,
Organism=Drosophila melanogaster, GI28574704, Length=378, Percent_Identity=25.6613756613757, Blast_Score=131, Evalue=9e-31,
Organism=Drosophila melanogaster, GI17136950, Length=378, Percent_Identity=25.6613756613757, Blast_Score=131, Evalue=9e-31,
Organism=Drosophila melanogaster, GI28574702, Length=378, Percent_Identity=25.6613756613757, Blast_Score=131, Evalue=9e-31,
Organism=Drosophila melanogaster, GI24762620, Length=414, Percent_Identity=25.3623188405797, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI221329674, Length=505, Percent_Identity=23.3663366336634, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24639514, Length=503, Percent_Identity=23.2604373757455, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24582567, Length=483, Percent_Identity=24.6376811594203, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI45550877, Length=416, Percent_Identity=23.5576923076923, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI45551183, Length=415, Percent_Identity=23.855421686747, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24639516, Length=523, Percent_Identity=22.1797323135755, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI19921936, Length=401, Percent_Identity=24.1895261845387, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI45551088, Length=377, Percent_Identity=25.7294429708223, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24652942, Length=377, Percent_Identity=25.7294429708223, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI281365034, Length=410, Percent_Identity=24.6341463414634, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24661428, Length=386, Percent_Identity=25.3886010362694, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281363702, Length=359, Percent_Identity=25.6267409470752, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI19921352, Length=416, Percent_Identity=24.7596153846154, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24584353, Length=416, Percent_Identity=24.7596153846154, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281363700, Length=302, Percent_Identity=25.1655629139073, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24654186, Length=179, Percent_Identity=30.7262569832402, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281364136, Length=305, Percent_Identity=25.2459016393443, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24655079, Length=303, Percent_Identity=24.0924092409241, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24582569, Length=453, Percent_Identity=22.2958057395143, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 48749; Mature: 48749

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]