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The map label for this gene is yqhT [H]

Identifier: 116872785

GI number: 116872785

Start: 1357686

End: 1358747

Strand: Direct

Name: yqhT [H]

Synonym: lwe1369

Alternate gene names: 116872785

Gene position: 1357686-1358747 (Clockwise)

Preceding gene: 116872781

Following gene: 116872786

Centisome position: 48.25

GC content: 35.78

Gene sequence:

>1062_bases
ATGTCTAAACTAACTAAAATTCAAGAAACACTTGGCAAAGAAAAGATTGAGGCAGTTCTTGTTACAAGTGAATTTAATAG
AAGGTATGTATCGGGTTTTACGGGTACAAGTGGTGTCGCACTCATTTTACCGGAAAAAGCTTATTTTATCACAGATTTTA
GATATACGGAACAAGCAGCGAAACAAGCAGAAGGATACGAAATCGTTAAACATACTGGACCTATTTTCGATACAGTAGAA
GAACTATTAGTAAAAAACGATACTAAAACGCTACATTTTGAAGCAGACTATGTAACGGTTTCGGAATTTAAACAAATGGA
GCGTATTTTTAATCGCCAATTAATCCCACTTACTGGGTTCTTTGAAGAAATGCGTAAAGTGAAAACAGCGAGTGAACTAA
AAGCCATTCGCACTGCTTGTGACATTGCAGATGCAGCATTTGCACACATCATTAAATTTATCAAACCGGGTATGGCAGAA
ATCGAAGTATCTAATGAACTAGAATTCTTTATGAGACGAGCTGGAGCTACTTCCTCTTCTTTCGATACAATTGTTGCTTC
TGGTCTTCGTTCAGCTTTACCACATGGTGTTGCAACTGATAAAAAAATCGAAGTTGGCGATTTTGTAACAATGGATTACG
GTTGTTATTATGATGGCTATTGTTCTGATATGACAAGAACGATTGCTGTAGGTGAACCCGCTGAAAAATTAAAAGAAATT
TATCAAATCACTTTGGATGCGCAATTAAAAGTAATTGATAGCTTAAAACCAGGTATGACCGGAATTGAAGCAGATGCTAT
TGCACGTGATTATATTTCTTCCTTTGGTTACGGTGACGCATTTGGTCACTCATTAGGTCATGGAATTGGATTAGAAATTC
ACGAAGGACCAAACTTATCTTTCAAAAGTCCTCAACAATTGGAAGTTGGACATGTAGTTACGGATGAACCAGGAATTTAT
TTACCAGGAATTGGTGGCGTTAGAATTGAAGATGATTTATTAATAACTGAAACTGGCAATGAGATTCTAATCCATTCTCC
AAAAGAATTAATTATTTTATAA

Upstream 100 bases:

>100_bases
AAAAAAGTTATTTTTTCTAAATTGTGATAAAATAGTTTCGAACGCGTTTAATAATGCGATTTTTGCGCGCCTAAAATTTA
ATTAAAGTGGGGGAATAATA

Downstream 100 bases:

>100_bases
GAATTCCTTTGTAACTTTGCGTGTTTTATGGTTAAATAAGGAAGAATGAGCAGTCTTAATATGCTCCAAATAAAGATACT
TTGCAAATTACAGGAGGAAA

Product: M24 family metallopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MSKLTKIQETLGKEKIEAVLVTSEFNRRYVSGFTGTSGVALILPEKAYFITDFRYTEQAAKQAEGYEIVKHTGPIFDTVE
ELLVKNDTKTLHFEADYVTVSEFKQMERIFNRQLIPLTGFFEEMRKVKTASELKAIRTACDIADAAFAHIIKFIKPGMAE
IEVSNELEFFMRRAGATSSSFDTIVASGLRSALPHGVATDKKIEVGDFVTMDYGCYYDGYCSDMTRTIAVGEPAEKLKEI
YQITLDAQLKVIDSLKPGMTGIEADAIARDYISSFGYGDAFGHSLGHGIGLEIHEGPNLSFKSPQQLEVGHVVTDEPGIY
LPGIGGVRIEDDLLITETGNEILIHSPKELIIL

Sequences:

>Translated_353_residues
MSKLTKIQETLGKEKIEAVLVTSEFNRRYVSGFTGTSGVALILPEKAYFITDFRYTEQAAKQAEGYEIVKHTGPIFDTVE
ELLVKNDTKTLHFEADYVTVSEFKQMERIFNRQLIPLTGFFEEMRKVKTASELKAIRTACDIADAAFAHIIKFIKPGMAE
IEVSNELEFFMRRAGATSSSFDTIVASGLRSALPHGVATDKKIEVGDFVTMDYGCYYDGYCSDMTRTIAVGEPAEKLKEI
YQITLDAQLKVIDSLKPGMTGIEADAIARDYISSFGYGDAFGHSLGHGIGLEIHEGPNLSFKSPQQLEVGHVVTDEPGIY
LPGIGGVRIEDDLLITETGNEILIHSPKELIIL
>Mature_352_residues
SKLTKIQETLGKEKIEAVLVTSEFNRRYVSGFTGTSGVALILPEKAYFITDFRYTEQAAKQAEGYEIVKHTGPIFDTVEE
LLVKNDTKTLHFEADYVTVSEFKQMERIFNRQLIPLTGFFEEMRKVKTASELKAIRTACDIADAAFAHIIKFIKPGMAEI
EVSNELEFFMRRAGATSSSFDTIVASGLRSALPHGVATDKKIEVGDFVTMDYGCYYDGYCSDMTRTIAVGEPAEKLKEIY
QITLDAQLKVIDSLKPGMTGIEADAIARDYISSFGYGDAFGHSLGHGIGLEIHEGPNLSFKSPQQLEVGHVVTDEPGIYL
PGIGGVRIEDDLLITETGNEILIHSPKELIIL

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI260593665, Length=328, Percent_Identity=28.0487804878049, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI149589008, Length=328, Percent_Identity=28.0487804878049, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI11559925, Length=261, Percent_Identity=28.735632183908, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI264681563, Length=227, Percent_Identity=32.5991189427313, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI264681565, Length=224, Percent_Identity=32.5892857142857, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI164420681, Length=244, Percent_Identity=25.4098360655738, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI93141226, Length=170, Percent_Identity=35.2941176470588, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1788728, Length=359, Percent_Identity=42.0612813370474, Blast_Score=287, Evalue=8e-79,
Organism=Escherichia coli, GI1789275, Length=270, Percent_Identity=31.1111111111111, Blast_Score=119, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17508215, Length=294, Percent_Identity=28.2312925170068, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17509539, Length=232, Percent_Identity=26.2931034482759, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71996291, Length=249, Percent_Identity=24.4979919678715, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321118, Length=295, Percent_Identity=27.4576271186441, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6320922, Length=272, Percent_Identity=26.1029411764706, Blast_Score=95, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6322999, Length=176, Percent_Identity=34.6590909090909, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI19920384, Length=280, Percent_Identity=30, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21357079, Length=295, Percent_Identity=27.4576271186441, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI21355531, Length=185, Percent_Identity=25.4054054054054, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161078230, Length=243, Percent_Identity=30.0411522633745, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21357287, Length=243, Percent_Identity=30.0411522633745, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 39059; Mature: 38928

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLTKIQETLGKEKIEAVLVTSEFNRRYVSGFTGTSGVALILPEKAYFITDFRYTEQAA
CCHHHHHHHHHCHHHEEEEEEECCCCCHHHCCCCCCCCEEEEECCCEEEEECHHHHHHHH
KQAEGYEIVKHTGPIFDTVEELLVKNDTKTLHFEADYVTVSEFKQMERIFNRQLIPLTGF
HHCCCCEEEHHCCCHHHHHHHHHHCCCCCEEEEEECEEEHHHHHHHHHHHCCCCCCHHHH
FEEMRKVKTASELKAIRTACDIADAAFAHIIKFIKPGMAEIEVSNELEFFMRRAGATSSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCCCCH
FDTIVASGLRSALPHGVATDKKIEVGDFVTMDYGCYYDGYCSDMTRTIAVGEPAEKLKEI
HHHHHHHHHHHHCCCCCCCCCEEECCCEEEECCCCCCCCHHHCCHHEEECCCHHHHHHHH
YQITLDAQLKVIDSLKPGMTGIEADAIARDYISSFGYGDAFGHSLGHGIGLEIHEGPNLS
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEECCCCCC
FKSPQQLEVGHVVTDEPGIYLPGIGGVRIEDDLLITETGNEILIHSPKELIIL
CCCCCCEECCEEEECCCCEEECCCCCEEEECCEEEEECCCEEEEECCCEEEEC
>Mature Secondary Structure 
SKLTKIQETLGKEKIEAVLVTSEFNRRYVSGFTGTSGVALILPEKAYFITDFRYTEQAA
CHHHHHHHHHCHHHEEEEEEECCCCCHHHCCCCCCCCEEEEECCCEEEEECHHHHHHHH
KQAEGYEIVKHTGPIFDTVEELLVKNDTKTLHFEADYVTVSEFKQMERIFNRQLIPLTGF
HHCCCCEEEHHCCCHHHHHHHHHHCCCCCEEEEEECEEEHHHHHHHHHHHCCCCCCHHHH
FEEMRKVKTASELKAIRTACDIADAAFAHIIKFIKPGMAEIEVSNELEFFMRRAGATSSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCCCCH
FDTIVASGLRSALPHGVATDKKIEVGDFVTMDYGCYYDGYCSDMTRTIAVGEPAEKLKEI
HHHHHHHHHHHHCCCCCCCCCEEECCCEEEECCCCCCCCHHHCCHHEEECCCHHHHHHHH
YQITLDAQLKVIDSLKPGMTGIEADAIARDYISSFGYGDAFGHSLGHGIGLEIHEGPNLS
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEECCCCCC
FKSPQQLEVGHVVTDEPGIYLPGIGGVRIEDDLLITETGNEILIHSPKELIIL
CCCCCCEECCEEEECCCCEEECCCCCEEEECCEEEEECCCEEEEECCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]