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The map label for this gene is glcK [H]

Identifier: 116872770

GI number: 116872770

Start: 1345289

End: 1346257

Strand: Direct

Name: glcK [H]

Synonym: lwe1354

Alternate gene names: 116872770

Gene position: 1345289-1346257 (Clockwise)

Preceding gene: 116872769

Following gene: 116872771

Centisome position: 47.8

GC content: 36.64

Gene sequence:

>969_bases
ATGAACAAAAAATTAATTGGTGTAGATTTAGGCGGTACAACCGCAAAATTAGCTATTTTAACAAAAGATGGAGATATTCA
AGAGAAATGGACGATTGATACTAATATCGAAGACAAAGGTTCTCATATTGTAAAAGATATTGGTGACTCCATTAATCAAA
AACTAACTGATTTACAGCTTGATAATGACAATTTTTACGGAATTGGAATGGGAACACCCGGAACTGTCAATTATGAAACT
GGAACTGTAAAAGGTGCTTATAATCTAGGTTGGGCAGAAGAGCAGAATATTAGCGAAGACTTAGAAAAAATTACCGGCTT
AACAATCAGATTGGACAATGATGCTAACGTAGCTGCTCTTGGTGAACGTTGGAAGGGTGCAGGAGAAGGCGGAGCAAACG
TTGTATTTGTTACACTTGGAACTGGCGTTGGCGGCGGAATTTTTGCAGAAGGAAAGATTTTACATGGTGTACGTGGTGCA
GCTGGTGAAATTGGCCATGTAACAGTAGTTCCAGAAAATGGTTATGACTGTACATGTGGTAAAAAAGGTTGTTTAGAAAC
TGTAGCATCTGCAACTGGTATTGTTCGTGTTGCAAAAGATTTCGCAAAAGAGTTTAATGGTGAATCCAAACTTAAAAAAG
CAATTGAAAATCAAGAAAATATTACATCTAAATTAATTTTTGAGTTAGGTGCTGAAGGCGATGAATTAGCAACAGAAACA
ATTGACAAAATTTCGTTTTACTTAGCTCTTGCGCTTAGTCATATAGGAAACATGTTAAATCCAGAAAAAATTATTATTGG
TGGCGGCGTTTCAGCAGCAGGAGATCAACTATTGACGCCAGTTAAAAATTATTTTGAAACGATGGTATTTCCAGCAGTTA
AAGAGTCGACCAAGTTATCTATTGCAACAAAAGGAAATGATGCGGGTATTATTGGCGCAGCTTGGTTAGCTTTACCAACA
GAAGATTAA

Upstream 100 bases:

>100_bases
AATATTTGCCACCGCTAGAAGCATCTTAAAACAAGAATTAATAAAAGAACAACGTAAAAATAGTAGTTTAAACTAAATTG
ATTAGAAGGAGAACAGCAAA

Downstream 100 bases:

>100_bases
TTTTATTTATACAAGCTACAATAACTTTCCATTATTGTAGCTTGTTTTTATAAGGATAACCTTCCAAAAGGGCATTGTTT
TAGCTTCCTATGAAAAGGGT

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MNKKLIGVDLGGTTAKLAILTKDGDIQEKWTIDTNIEDKGSHIVKDIGDSINQKLTDLQLDNDNFYGIGMGTPGTVNYET
GTVKGAYNLGWAEEQNISEDLEKITGLTIRLDNDANVAALGERWKGAGEGGANVVFVTLGTGVGGGIFAEGKILHGVRGA
AGEIGHVTVVPENGYDCTCGKKGCLETVASATGIVRVAKDFAKEFNGESKLKKAIENQENITSKLIFELGAEGDELATET
IDKISFYLALALSHIGNMLNPEKIIIGGGVSAAGDQLLTPVKNYFETMVFPAVKESTKLSIATKGNDAGIIGAAWLALPT
ED

Sequences:

>Translated_322_residues
MNKKLIGVDLGGTTAKLAILTKDGDIQEKWTIDTNIEDKGSHIVKDIGDSINQKLTDLQLDNDNFYGIGMGTPGTVNYET
GTVKGAYNLGWAEEQNISEDLEKITGLTIRLDNDANVAALGERWKGAGEGGANVVFVTLGTGVGGGIFAEGKILHGVRGA
AGEIGHVTVVPENGYDCTCGKKGCLETVASATGIVRVAKDFAKEFNGESKLKKAIENQENITSKLIFELGAEGDELATET
IDKISFYLALALSHIGNMLNPEKIIIGGGVSAAGDQLLTPVKNYFETMVFPAVKESTKLSIATKGNDAGIIGAAWLALPT
ED
>Mature_322_residues
MNKKLIGVDLGGTTAKLAILTKDGDIQEKWTIDTNIEDKGSHIVKDIGDSINQKLTDLQLDNDNFYGIGMGTPGTVNYET
GTVKGAYNLGWAEEQNISEDLEKITGLTIRLDNDANVAALGERWKGAGEGGANVVFVTLGTGVGGGIFAEGKILHGVRGA
AGEIGHVTVVPENGYDCTCGKKGCLETVASATGIVRVAKDFAKEFNGESKLKKAIENQENITSKLIFELGAEGDELATET
IDKISFYLALALSHIGNMLNPEKIIIGGGVSAAGDQLLTPVKNYFETMVFPAVKESTKLSIATKGNDAGIIGAAWLALPT
ED

Specific function: Unknown

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=273, Percent_Identity=30.4029304029304, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI298566315, Length=273, Percent_Identity=30.4029304029304, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI4885285, Length=273, Percent_Identity=30.4029304029304, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI190014632, Length=273, Percent_Identity=30.4029304029304, Blast_Score=88, Evalue=9e-18,
Organism=Escherichia coli, GI87081733, Length=321, Percent_Identity=33.3333333333333, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787878, Length=274, Percent_Identity=26.6423357664234, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787363, Length=325, Percent_Identity=28.6153846153846, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786891, Length=300, Percent_Identity=27, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI87082127, Length=220, Percent_Identity=25.9090909090909, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87082230, Length=280, Percent_Identity=28.2142857142857, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790522, Length=323, Percent_Identity=24.4582043343653, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 33934; Mature: 33934

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKLIGVDLGGTTAKLAILTKDGDIQEKWTIDTNIEDKGSHIVKDIGDSINQKLTDLQL
CCCEEEEEECCCCEEEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHEEEE
DNDNFYGIGMGTPGTVNYETGTVKGAYNLGWAEEQNISEDLEKITGLTIRLDNDANVAAL
CCCCEEEEECCCCCEEEECCCEECCCCCCCCCCCCCHHHHHHHHCCEEEEECCCCCEEEH
GERWKGAGEGGANVVFVTLGTGVGGGIFAEGKILHGVRGAAGEIGHVTVVPENGYDCTCG
HHHCCCCCCCCCEEEEEEECCCCCCCEEECCEEEECCCCCCCCCCEEEEEECCCCCCCCC
KKGCLETVASATGIVRVAKDFAKEFNGESKLKKAIENQENITSKLIFELGAEGDELATET
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
IDKISFYLALALSHIGNMLNPEKIIIGGGVSAAGDQLLTPVKNYFETMVFPAVKESTKLS
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEE
IATKGNDAGIIGAAWLALPTED
EEECCCCCCEEEEEEEEECCCC
>Mature Secondary Structure
MNKKLIGVDLGGTTAKLAILTKDGDIQEKWTIDTNIEDKGSHIVKDIGDSINQKLTDLQL
CCCEEEEEECCCCEEEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHEEEE
DNDNFYGIGMGTPGTVNYETGTVKGAYNLGWAEEQNISEDLEKITGLTIRLDNDANVAAL
CCCCEEEEECCCCCEEEECCCEECCCCCCCCCCCCCHHHHHHHHCCEEEEECCCCCEEEH
GERWKGAGEGGANVVFVTLGTGVGGGIFAEGKILHGVRGAAGEIGHVTVVPENGYDCTCG
HHHCCCCCCCCCEEEEEEECCCCCCCEEECCEEEECCCCCCCCCCEEEEEECCCCCCCCC
KKGCLETVASATGIVRVAKDFAKEFNGESKLKKAIENQENITSKLIFELGAEGDELATET
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
IDKISFYLALALSHIGNMLNPEKIIIGGGVSAAGDQLLTPVKNYFETMVFPAVKESTKLS
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEE
IATKGNDAGIIGAAWLALPTED
EEECCCCCCEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]