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The map label for this gene is rbgA [H]

Identifier: 116872705

GI number: 116872705

Start: 1278088

End: 1278951

Strand: Direct

Name: rbgA [H]

Synonym: lwe1289

Alternate gene names: 116872705

Gene position: 1278088-1278951 (Clockwise)

Preceding gene: 116872704

Following gene: 116872706

Centisome position: 45.42

GC content: 36.81

Gene sequence:

>864_bases
ATGACAATTCAATGGTTTCCAGGTCATATGGCCAAAGCTCGTCGTGAGGTAACAGAAAAATTAAAATTAGTGGATGTGAT
TTTTGAATTAGTAGACGCGCGAATTCCGCTTTCTTCTTCAAATCCAATGTTGGAAGAAATCATTCACCAAAAAAGACGAG
TGATAATTTTAAATAAAGCAGATACAGCAGATGAAAAAACGACCAAAGAATGGATTGATTATTTTGCAGATAAAGGCTTG
CCTGCTGTAGCGGTTAATGCTCAAGAAGGTAAAGGACTCTTCAAAATAGAACAAGCAGCAGAAAAATTAATGGCTGAAAA
ATTTGATCGCTTAAGAAGTAAAGGTATGAAACCTAGAGCGATTCGAGCGATGATTTTGGGAATTCCAAACGTCGGGAAAT
CTACTTTAATTAATCGATTAGCCAAAAAAAATATTGCTCGAACTGGTAATAAGCCTGGTGTAACAAAAGCACAACAATGG
ATTAAAGTCGGAAAAACGTTAGAGCTTCTTGATACCCCAGGGATATTATGGCCAAAATTTGAAGATCAAGAAATTGGTTA
CAAACTGGCTTTAACAGGTGCTATTAAAGATGATTTACTTCAAATGGAAGATATCGCTGGCTATGGTTTACGGTTTTTAG
AAAAAAATTATCCGGACCGGCTCGAAAACTGGTTGAAGGTAGAGAAAGTTTCGGAAGATCCAATTGAAACCCTAGCTTTT
ATTGCTGAAAAACGAGGACTTTTAGATCGATATAATGATCCAGATTATTCACGCGCAGCTGAAACAGTTGTTCGTGAAAT
TCGTCAACAAAAACTGGGAAGAATGTCCTTTGATTTTCCTAACTGGGAAGATGATGCGAAATGA

Upstream 100 bases:

>100_bases
CAGAATAATTGGTCCAATTCCTTTAAGCAAAGTATTAGGAACGACACCAATTTGTTATTGGCCGATTAAAGACGCCAAAC
TTATAGATTAGGAGTATATG

Downstream 100 bases:

>100_bases
GTGAATCTATCTCCGTTATTCGAGAGAAACTAAGTCATGTGATCTCGGAACAAGATGCTTTTTTTCAATTATGTTTACAA
GATGAACGTAAAGGTGTTAT

Product: ribosomal biogenesis GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MTIQWFPGHMAKARREVTEKLKLVDVIFELVDARIPLSSSNPMLEEIIHQKRRVIILNKADTADEKTTKEWIDYFADKGL
PAVAVNAQEGKGLFKIEQAAEKLMAEKFDRLRSKGMKPRAIRAMILGIPNVGKSTLINRLAKKNIARTGNKPGVTKAQQW
IKVGKTLELLDTPGILWPKFEDQEIGYKLALTGAIKDDLLQMEDIAGYGLRFLEKNYPDRLENWLKVEKVSEDPIETLAF
IAEKRGLLDRYNDPDYSRAAETVVREIRQQKLGRMSFDFPNWEDDAK

Sequences:

>Translated_287_residues
MTIQWFPGHMAKARREVTEKLKLVDVIFELVDARIPLSSSNPMLEEIIHQKRRVIILNKADTADEKTTKEWIDYFADKGL
PAVAVNAQEGKGLFKIEQAAEKLMAEKFDRLRSKGMKPRAIRAMILGIPNVGKSTLINRLAKKNIARTGNKPGVTKAQQW
IKVGKTLELLDTPGILWPKFEDQEIGYKLALTGAIKDDLLQMEDIAGYGLRFLEKNYPDRLENWLKVEKVSEDPIETLAF
IAEKRGLLDRYNDPDYSRAAETVVREIRQQKLGRMSFDFPNWEDDAK
>Mature_286_residues
TIQWFPGHMAKARREVTEKLKLVDVIFELVDARIPLSSSNPMLEEIIHQKRRVIILNKADTADEKTTKEWIDYFADKGLP
AVAVNAQEGKGLFKIEQAAEKLMAEKFDRLRSKGMKPRAIRAMILGIPNVGKSTLINRLAKKNIARTGNKPGVTKAQQWI
KVGKTLELLDTPGILWPKFEDQEIGYKLALTGAIKDDLLQMEDIAGYGLRFLEKNYPDRLENWLKVEKVSEDPIETLAFI
AEKRGLLDRYNDPDYSRAAETVVREIRQQKLGRMSFDFPNWEDDAK

Specific function: Binds GTP and GDP [H]

COG id: COG1161

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI93277113, Length=296, Percent_Identity=32.0945945945946, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI296317324, Length=184, Percent_Identity=33.695652173913, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI9506611, Length=184, Percent_Identity=33.695652173913, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI7019419, Length=264, Percent_Identity=28.030303030303, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI45643129, Length=185, Percent_Identity=29.7297297297297, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI45643127, Length=185, Percent_Identity=29.7297297297297, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI45593130, Length=185, Percent_Identity=29.7297297297297, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI193211047, Length=228, Percent_Identity=29.8245614035088, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17534827, Length=269, Percent_Identity=30.4832713754647, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI32563985, Length=244, Percent_Identity=26.6393442622951, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71990926, Length=244, Percent_Identity=26.6393442622951, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32563983, Length=244, Percent_Identity=26.6393442622951, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI25143545, Length=285, Percent_Identity=26.6666666666667, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI115535155, Length=286, Percent_Identity=26.9230769230769, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71982363, Length=191, Percent_Identity=27.2251308900524, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323744, Length=229, Percent_Identity=29.6943231441048, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324381, Length=263, Percent_Identity=25.8555133079848, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6320842, Length=170, Percent_Identity=31.1764705882353, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI85815858, Length=309, Percent_Identity=31.3915857605178, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28572990, Length=175, Percent_Identity=35.4285714285714, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI19922460, Length=262, Percent_Identity=26.7175572519084, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023179
- InterPro:   IPR019991
- InterPro:   IPR016478
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 32839; Mature: 32708

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIQWFPGHMAKARREVTEKLKLVDVIFELVDARIPLSSSNPMLEEIIHQKRRVIILNKA
CEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEEECC
DTADEKTTKEWIDYFADKGLPAVAVNAQEGKGLFKIEQAAEKLMAEKFDRLRSKGMKPRA
CCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHH
IRAMILGIPNVGKSTLINRLAKKNIARTGNKPGVTKAQQWIKVGKTLELLDTPGILWPKF
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHCCCCCCCCCC
EDQEIGYKLALTGAIKDDLLQMEDIAGYGLRFLEKNYPDRLENWLKVEKVSEDPIETLAF
CCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHH
IAEKRGLLDRYNDPDYSRAAETVVREIRQQKLGRMSFDFPNWEDDAK
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TIQWFPGHMAKARREVTEKLKLVDVIFELVDARIPLSSSNPMLEEIIHQKRRVIILNKA
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEEECC
DTADEKTTKEWIDYFADKGLPAVAVNAQEGKGLFKIEQAAEKLMAEKFDRLRSKGMKPRA
CCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHH
IRAMILGIPNVGKSTLINRLAKKNIARTGNKPGVTKAQQWIKVGKTLELLDTPGILWPKF
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHCCCCCCCCCC
EDQEIGYKLALTGAIKDDLLQMEDIAGYGLRFLEKNYPDRLENWLKVEKVSEDPIETLAF
CCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHH
IAEKRGLLDRYNDPDYSRAAETVVREIRQQKLGRMSFDFPNWEDDAK
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]