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The map label for this gene is pduP [H]

Identifier: 116872539

GI number: 116872539

Start: 1134599

End: 1136008

Strand: Direct

Name: pduP [H]

Synonym: lwe1123

Alternate gene names: 116872539

Gene position: 1134599-1136008 (Clockwise)

Preceding gene: 116872538

Following gene: 116872540

Centisome position: 40.32

GC content: 38.51

Gene sequence:

>1410_bases
ATGGAATCATTAGAACTCGAACAACTGGTGAAAAAAGTTCTGTTAGAAAAATTAGCTGAACAAAAAGATGTACCAGTAAA
AACAACTACACAAGGCGCAAAAAGTGGGATTTTTGATACAGTGGATGAGGCAGTTCAAGCAGCTGTCCAAGCACAAAATA
GTTATAAAGAAAAATCTCTGGAAGAACGCCGCAATGTAGTAAAAGCAATTCGTGAAGCACTTTATCCAGAAATTGAGTCA
ATTGCCACAAGAGCAGTTGCTGAAACAGGAATGGGTAATGTGACAGATAAAATTTTGAAAAATACTTTAGCGATTGAAAA
AACGCCGGGCGTAGAAGATTTATATACAGAAGTAGCTACTGGTGATAATGGCATGACGCTTTATGAATTATCTCCGTATG
GTGTAATTGGTGCTGTGGCGCCGAGTACGAATCCAACCGAAACGTTAATTTGTAATACAATCGGTATGCTTGCAGCTGGG
AATGCAGTGTTTTATAGCCCACATCCTGGTGCAAAAAATATATCTCTTTGGTTGATTGAAAAGTTGAATACGATTGTTCG
TGAAAGTTGTGGTATTGATAACTTGGTTGTGACAGTGGAAAAACCTTCCATTCAAGCAGCGCAAGAAATGATGAATCATC
CAAAAGTACCATTACTTGTCATTACAGGTGGACCAGGCGTCGTGCTTCAAGCAATGCAATCAGGTAAAAAAGTCATTGGA
GCTGGTGCCGGAAATCCGCCTTCCATCGTAGACGAAACAGCTAATATCGAAAAAGCTGCAGCCGATATTGTTGACGGAGC
CTCTTTTGACCACAATATCTTATGTATTGCTGAAAAAAGCGTTGTTGCCGTTGATAGCATTACTGATTTCCTATTATTCC
AAATGGAAAAAAATGGAGCACTACATGTGACCAATCCGAGCGATATTAAAAAATTAGAAAAAGTTGCTGTAACGGATAAA
GGTGTAACGAATAAAAAATTAGTCGGAAAAAGCGCTTCTGAAATTTTAAAAGAAGCTGGAATAACTTGTGATTTTACCCC
GCGATTAATCATTGTGGAAACAGATAAATCACATCCATTTGCAACAGTAGAATTACTAATGCCAATCGTTCCAGTGGTAA
GAGTGCCTGATTTTGATGAAGCGCTTAAAGTAGCTATTGAATTAGAACAAGGACTACATCATACAGCAACAATGCATTCA
CAAAATATTTCCAGATTAAATAAAGCTGCAAGAGATATGCAAACATCGATCTTTGTGAAAAATGGTCCTTCCTTTGCAGG
TTTAGGTTTTAGAGGGGAAGGTAGTACTACATTTACTATTGCAACCCCAACTGGAGAAGGAACCACTACAGCACGTCATT
TTGCTAGACGCCGCCGTTGTGTTTTAACAGATGGTTTTTCGATTCGTTAA

Upstream 100 bases:

>100_bases
AGCAATTATTGGTGGAATGGGAATTAGCGGCGGTTCAGTGGAAGAAGATATCCACATTGCAAAAAAAGCATTATCAATGA
TAGAGAAGGGGTAATTCTGT

Downstream 100 bases:

>100_bases
GAGGAGGCAAAGTTAATGAATAGCTTTCAAATCAAGACAAAAGTAGCTTTTGGTACGAATAGTTTACAAGTATTAAAAGA
AATTAAAAATAAAAATGTCT

Product: CoA-dependent propionaldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MESLELEQLVKKVLLEKLAEQKDVPVKTTTQGAKSGIFDTVDEAVQAAVQAQNSYKEKSLEERRNVVKAIREALYPEIES
IATRAVAETGMGNVTDKILKNTLAIEKTPGVEDLYTEVATGDNGMTLYELSPYGVIGAVAPSTNPTETLICNTIGMLAAG
NAVFYSPHPGAKNISLWLIEKLNTIVRESCGIDNLVVTVEKPSIQAAQEMMNHPKVPLLVITGGPGVVLQAMQSGKKVIG
AGAGNPPSIVDETANIEKAAADIVDGASFDHNILCIAEKSVVAVDSITDFLLFQMEKNGALHVTNPSDIKKLEKVAVTDK
GVTNKKLVGKSASEILKEAGITCDFTPRLIIVETDKSHPFATVELLMPIVPVVRVPDFDEALKVAIELEQGLHHTATMHS
QNISRLNKAARDMQTSIFVKNGPSFAGLGFRGEGSTTFTIATPTGEGTTTARHFARRRRCVLTDGFSIR

Sequences:

>Translated_469_residues
MESLELEQLVKKVLLEKLAEQKDVPVKTTTQGAKSGIFDTVDEAVQAAVQAQNSYKEKSLEERRNVVKAIREALYPEIES
IATRAVAETGMGNVTDKILKNTLAIEKTPGVEDLYTEVATGDNGMTLYELSPYGVIGAVAPSTNPTETLICNTIGMLAAG
NAVFYSPHPGAKNISLWLIEKLNTIVRESCGIDNLVVTVEKPSIQAAQEMMNHPKVPLLVITGGPGVVLQAMQSGKKVIG
AGAGNPPSIVDETANIEKAAADIVDGASFDHNILCIAEKSVVAVDSITDFLLFQMEKNGALHVTNPSDIKKLEKVAVTDK
GVTNKKLVGKSASEILKEAGITCDFTPRLIIVETDKSHPFATVELLMPIVPVVRVPDFDEALKVAIELEQGLHHTATMHS
QNISRLNKAARDMQTSIFVKNGPSFAGLGFRGEGSTTFTIATPTGEGTTTARHFARRRRCVLTDGFSIR
>Mature_469_residues
MESLELEQLVKKVLLEKLAEQKDVPVKTTTQGAKSGIFDTVDEAVQAAVQAQNSYKEKSLEERRNVVKAIREALYPEIES
IATRAVAETGMGNVTDKILKNTLAIEKTPGVEDLYTEVATGDNGMTLYELSPYGVIGAVAPSTNPTETLICNTIGMLAAG
NAVFYSPHPGAKNISLWLIEKLNTIVRESCGIDNLVVTVEKPSIQAAQEMMNHPKVPLLVITGGPGVVLQAMQSGKKVIG
AGAGNPPSIVDETANIEKAAADIVDGASFDHNILCIAEKSVVAVDSITDFLLFQMEKNGALHVTNPSDIKKLEKVAVTDK
GVTNKKLVGKSASEILKEAGITCDFTPRLIIVETDKSHPFATVELLMPIVPVVRVPDFDEALKVAIELEQGLHHTATMHS
QNISRLNKAARDMQTSIFVKNGPSFAGLGFRGEGSTTFTIATPTGEGTTTARHFARRRRCVLTDGFSIR

Specific function: May act as an acetaldehyde dehydrogenase that converts acetaldehyde into acetyl-CoA [H]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI12007648, Length=421, Percent_Identity=23.7529691211401, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1788797, Length=474, Percent_Identity=46.6244725738397, Blast_Score=374, Evalue=1e-105,
Organism=Escherichia coli, GI1787493, Length=404, Percent_Identity=31.6831683168317, Blast_Score=166, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6323822, Length=407, Percent_Identity=24.3243243243243, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012408
- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: NA

Molecular weight: Translated: 50400; Mature: 50400

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESLELEQLVKKVLLEKLAEQKDVPVKTTTQGAKSGIFDTVDEAVQAAVQAQNSYKEKSL
CCCCCHHHHHHHHHHHHHHHHCCCCCEECCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHH
EERRNVVKAIREALYPEIESIATRAVAETGMGNVTDKILKNTLAIEKTPGVEDLYTEVAT
HHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHC
GDNGMTLYELSPYGVIGAVAPSTNPTETLICNTIGMLAAGNAVFYSPHPGAKNISLWLIE
CCCCEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHH
KLNTIVRESCGIDNLVVTVEKPSIQAAQEMMNHPKVPLLVITGGPGVVLQAMQSGKKVIG
HHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCEEEE
AGAGNPPSIVDETANIEKAAADIVDGASFDHNILCIAEKSVVAVDSITDFLLFQMEKNGA
CCCCCCCHHHCCCCCHHHHHHHHHCCCCCCCCEEEEECCCEEEHHHHHHHHHEEECCCCE
LHVTNPSDIKKLEKVAVTDKGVTNKKLVGKSASEILKEAGITCDFTPRLIIVETDKSHPF
EEECCHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHCCCEEECCCCEEEEECCCCCCH
ATVELLMPIVPVVRVPDFDEALKVAIELEQGLHHTATMHSQNISRLNKAARDMQTSIFVK
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEEEE
NGPSFAGLGFRGEGSTTFTIATPTGEGTTTARHFARRRRCVLTDGFSIR
CCCCEECCEEECCCCEEEEEECCCCCCCHHHHHHHHHCCEEECCCCCCC
>Mature Secondary Structure
MESLELEQLVKKVLLEKLAEQKDVPVKTTTQGAKSGIFDTVDEAVQAAVQAQNSYKEKSL
CCCCCHHHHHHHHHHHHHHHHCCCCCEECCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHH
EERRNVVKAIREALYPEIESIATRAVAETGMGNVTDKILKNTLAIEKTPGVEDLYTEVAT
HHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHC
GDNGMTLYELSPYGVIGAVAPSTNPTETLICNTIGMLAAGNAVFYSPHPGAKNISLWLIE
CCCCEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHH
KLNTIVRESCGIDNLVVTVEKPSIQAAQEMMNHPKVPLLVITGGPGVVLQAMQSGKKVIG
HHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCEEEE
AGAGNPPSIVDETANIEKAAADIVDGASFDHNILCIAEKSVVAVDSITDFLLFQMEKNGA
CCCCCCCHHHCCCCCHHHHHHHHHCCCCCCCCEEEEECCCEEEHHHHHHHHHEEECCCCE
LHVTNPSDIKKLEKVAVTDKGVTNKKLVGKSASEILKEAGITCDFTPRLIIVETDKSHPF
EEECCHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHCCCEEECCCCEEEEECCCCCCH
ATVELLMPIVPVVRVPDFDEALKVAIELEQGLHHTATMHSQNISRLNKAARDMQTSIFVK
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEEEE
NGPSFAGLGFRGEGSTTFTIATPTGEGTTTARHFARRRRCVLTDGFSIR
CCCCEECCEEECCCCEEEEEECCCCCCCHHHHHHHHHCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]