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The map label for this gene is cobC [H]

Identifier: 116872523

GI number: 116872523

Start: 1122210

End: 1122785

Strand: Direct

Name: cobC [H]

Synonym: lwe1107

Alternate gene names: 116872523

Gene position: 1122210-1122785 (Clockwise)

Preceding gene: 116872522

Following gene: 116872525

Centisome position: 39.88

GC content: 35.76

Gene sequence:

>576_bases
GTGCGACTTATTTTTGTGCGGCACGGAGAGACAGACTTGAATTTAGCTAGAAAATATTGTGGACAACTAGATGTTGGTTT
AAATGAACACGGGGTTCAGCAGATGGAGTTGCTGCGAGAAAAGCTTGATTCTTATTCGATTGATTTAGTTATTACAAGCG
ATTTACTGCGAGCACATCAGTCTGCTGAAATTCTAACTGATGTGAAAGCGTTTTGTTTTCCTGCATTTAATGAGATGGAT
TTTGGCGATTTTGAGGGATATACATATCAAGAAATTTACGCTAAGTTTCCTTTAGATTGGGCTAACTATTGTAATAATTG
GCAAACTGCAATATTTCCAAATGGAGAAAGCTTCCCGATTTTTTATGATCGTGTGATTGCTGCTTTTATGGAAGAATGGA
AAAAATGGCAGCAGTTCGATACTGTTTTGTTTGTTGGACATCTTGGGGTTTTAAGAGTAATTGCGCTTTTTTTACAAAAA
CAAAAAATAGCATTTTATTGGGATAACGATTTTAAGCAAGGTACTTATTCACTCTGGGACAATGAGTCTCAAAGGTTTGT
TATTTTGAATCAATAG

Upstream 100 bases:

>100_bases
ACGAATTGGTGGCATGAATGGAGATACGCTCGGTGCTGGTGGACAGATGGGGCAACTGGTGTGTTTATTTTGTCTAGTGC
TAGTTTGGGGGTTGATTTAA

Downstream 100 bases:

>100_bases
TATATTTTTGTCATGTCAGAGGGAAAAGCGTATTTTATAAGTCCTTTATGGTAAAATATAGATAGTTAAATAGGTCTTAA
GTTGGTGAAATGTATTTGCA

Product: alpha-ribazole-5'-phosphate phosphatase

Products: NA

Alternate protein names: Alpha-ribazole-5'-phosphate phosphatase [H]

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MRLIFVRHGETDLNLARKYCGQLDVGLNEHGVQQMELLREKLDSYSIDLVITSDLLRAHQSAEILTDVKAFCFPAFNEMD
FGDFEGYTYQEIYAKFPLDWANYCNNWQTAIFPNGESFPIFYDRVIAAFMEEWKKWQQFDTVLFVGHLGVLRVIALFLQK
QKIAFYWDNDFKQGTYSLWDNESQRFVILNQ

Sequences:

>Translated_191_residues
MRLIFVRHGETDLNLARKYCGQLDVGLNEHGVQQMELLREKLDSYSIDLVITSDLLRAHQSAEILTDVKAFCFPAFNEMD
FGDFEGYTYQEIYAKFPLDWANYCNNWQTAIFPNGESFPIFYDRVIAAFMEEWKKWQQFDTVLFVGHLGVLRVIALFLQK
QKIAFYWDNDFKQGTYSLWDNESQRFVILNQ
>Mature_191_residues
MRLIFVRHGETDLNLARKYCGQLDVGLNEHGVQQMELLREKLDSYSIDLVITSDLLRAHQSAEILTDVKAFCFPAFNEMD
FGDFEGYTYQEIYAKFPLDWANYCNNWQTAIFPNGESFPIFYDRVIAAFMEEWKKWQQFDTVLFVGHLGVLRVIALFLQK
QKIAFYWDNDFKQGTYSLWDNESQRFVILNQ

Specific function: Converts N1-(5-phospho-alpha-D-ribosyl)-5,6- dimethylbenzimidazole into N1-alpha-D-ribosyl-5,6- dimethylbenzimidazole; involved in the assembly of the nucleotide loop of cobalamin [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family [H]

Homologues:

Organism=Escherichia coli, GI1786857, Length=192, Percent_Identity=33.8541666666667, Blast_Score=102, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR017578 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =3.1.3.73 [H]

Molecular weight: Translated: 22587; Mature: 22587

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLIFVRHGETDLNLARKYCGQLDVGLNEHGVQQMELLREKLDSYSIDLVITSDLLRAHQ
CEEEEEECCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEHHHHHHHH
SAEILTDVKAFCFPAFNEMDFGDFEGYTYQEIYAKFPLDWANYCNNWQTAIFPNGESFPI
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHCCCCCEEECCCCCCCCH
FYDRVIAAFMEEWKKWQQFDTVLFVGHLGVLRVIALFLQKQKIAFYWDNDFKQGTYSLWD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEECC
NESQRFVILNQ
CCCCEEEEEEC
>Mature Secondary Structure
MRLIFVRHGETDLNLARKYCGQLDVGLNEHGVQQMELLREKLDSYSIDLVITSDLLRAHQ
CEEEEEECCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEHHHHHHHH
SAEILTDVKAFCFPAFNEMDFGDFEGYTYQEIYAKFPLDWANYCNNWQTAIFPNGESFPI
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHCCCCCEEECCCCCCCCH
FYDRVIAAFMEEWKKWQQFDTVLFVGHLGVLRVIALFLQKQKIAFYWDNDFKQGTYSLWD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEECC
NESQRFVILNQ
CCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]