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The map label for this gene is yhcG [H]

Identifier: 116872128

GI number: 116872128

Start: 733794

End: 734483

Strand: Direct

Name: yhcG [H]

Synonym: lwe0708

Alternate gene names: 116872128

Gene position: 733794-734483 (Clockwise)

Preceding gene: 116872127

Following gene: 116872129

Centisome position: 26.08

GC content: 34.49

Gene sequence:

>690_bases
ATGTTGGTGGGAAATAATATTGCGAAATCATATCCAAATAAATTAGTGTTACAAAACTTGGATTTTGAAGCAAAACCAGG
CGACATGATTGTACTAACTGGTGAAAACGGTAGTGGCAAAACGACCTTGCTAGATATGTTAGCGAATTTGAAGAAACCAG
ATAGTGGCACATTAGAATTAGATAATGAAGTTTTTGCTGCTAATAACATCCGTCAGCACATCGCTTATCTAAATAATGAA
CTTTATGCTAAAAAAAGTATCACCATCGAAGAATTTATGAAACAACATGCTTTGCTTTTTGAAGATATTCAATTAGATAA
ATGGGACAGATTGCTTTCAGGCTGGCGCATTAACAAGCGGCTAAAACTTGGTGAATTATCGACTGGTATGCTAATGAAAG
TGAAAATTGGCGGTGTTTTAGCAAGAAAAGCCAAAGTATATCTTTATGATGAACCTTTTGCGAACATCGATATTATGGCT
CGTTCAGAAGTAATGAAAGCTATTATTAGCGAAACAGAGCCAGATGTTATCACGATTATTTCTTCGCATCATTTAGAAGG
AACGGAAAAATTATATAACAAACTGTGGTTAATCAAAGAAGGCACACTAAAAATAATTGAAACAGAAGATTACCGCGAGG
AAACAGGCAATTCATTAATCGATTTCTATAAGGAGGAAATGAACAAATGA

Upstream 100 bases:

>100_bases
AAACAACTTACCGAAAATTTTATTAACGAAATGAGTAAATTAGGAATTAATAAAGAAAAAATTATCGCTTGGGTGAAAAA
AGTAGAGGAGGTAGAAGTTA

Downstream 100 bases:

>100_bases
AAAAAATGATTACTTTTTATTTAAAACAAATTAGTCCTATTCTTTTAATCGGGCTTGCAATTATCTTAGGACTGAATTTA
GTAGGCCTAACAATGAATCT

Product: ABC transporter, ATP-binding protein

Products: ADP; phosphate; L-glutamine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MLVGNNIAKSYPNKLVLQNLDFEAKPGDMIVLTGENGSGKTTLLDMLANLKKPDSGTLELDNEVFAANNIRQHIAYLNNE
LYAKKSITIEEFMKQHALLFEDIQLDKWDRLLSGWRINKRLKLGELSTGMLMKVKIGGVLARKAKVYLYDEPFANIDIMA
RSEVMKAIISETEPDVITIISSHHLEGTEKLYNKLWLIKEGTLKIIETEDYREETGNSLIDFYKEEMNK

Sequences:

>Translated_229_residues
MLVGNNIAKSYPNKLVLQNLDFEAKPGDMIVLTGENGSGKTTLLDMLANLKKPDSGTLELDNEVFAANNIRQHIAYLNNE
LYAKKSITIEEFMKQHALLFEDIQLDKWDRLLSGWRINKRLKLGELSTGMLMKVKIGGVLARKAKVYLYDEPFANIDIMA
RSEVMKAIISETEPDVITIISSHHLEGTEKLYNKLWLIKEGTLKIIETEDYREETGNSLIDFYKEEMNK
>Mature_229_residues
MLVGNNIAKSYPNKLVLQNLDFEAKPGDMIVLTGENGSGKTTLLDMLANLKKPDSGTLELDNEVFAANNIRQHIAYLNNE
LYAKKSITIEEFMKQHALLFEDIQLDKWDRLLSGWRINKRLKLGELSTGMLMKVKIGGVLARKAKVYLYDEPFANIDIMA
RSEVMKAIISETEPDVITIISSHHLEGTEKLYNKLWLIKEGTLKIIETEDYREETGNSLIDFYKEEMNK

Specific function: Part Of The Binding-Protein-Dependent Transport System For Glutamine. Probably Responsible For Energy Coupling To The Transport System. [C]

COG id: COG1131

COG function: function code V; ABC-type multidrug transport system, ATPase component

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI27881501, Length=223, Percent_Identity=25.5605381165919, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI30795238, Length=223, Percent_Identity=25.5605381165919, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI31657092, Length=214, Percent_Identity=24.7663551401869, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI27436953, Length=202, Percent_Identity=25.2475247524752, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI153792144, Length=213, Percent_Identity=27.2300469483568, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI45446740, Length=225, Percent_Identity=25.3333333333333, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI47078218, Length=225, Percent_Identity=25.3333333333333, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787029, Length=216, Percent_Identity=27.7777777777778, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788225, Length=220, Percent_Identity=24.5454545454545, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI1789593, Length=212, Percent_Identity=24.0566037735849, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1789672, Length=221, Percent_Identity=24.8868778280543, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1788165, Length=155, Percent_Identity=26.4516129032258, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87081782, Length=218, Percent_Identity=28.8990825688073, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786319, Length=212, Percent_Identity=24.5283018867925, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787089, Length=222, Percent_Identity=24.7747747747748, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1790739, Length=213, Percent_Identity=26.2910798122066, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1788761, Length=247, Percent_Identity=23.0769230769231, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1787105, Length=198, Percent_Identity=27.7777777777778, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI48995001, Length=211, Percent_Identity=23.696682464455, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1789991, Length=210, Percent_Identity=24.7619047619048, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788210, Length=208, Percent_Identity=24.5192307692308, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87081709, Length=236, Percent_Identity=24.1525423728814, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1788472, Length=220, Percent_Identity=22.7272727272727, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1786563, Length=218, Percent_Identity=22.9357798165138, Blast_Score=60, Evalue=9e-11,
Organism=Escherichia coli, GI1787792, Length=214, Percent_Identity=23.3644859813084, Blast_Score=60, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=216, Percent_Identity=25, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24666092, Length=218, Percent_Identity=27.9816513761468, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221512771, Length=219, Percent_Identity=25.5707762557078, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24643674, Length=227, Percent_Identity=26.431718061674, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI116007328, Length=204, Percent_Identity=25.4901960784314, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28574150, Length=204, Percent_Identity=25.4901960784314, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 26141; Mature: 26141

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVGNNIAKSYPNKLVLQNLDFEAKPGDMIVLTGENGSGKTTLLDMLANLKKPDSGTLEL
CCCCCCHHHHCCCEEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEE
DNEVFAANNIRQHIAYLNNELYAKKSITIEEFMKQHALLFEDIQLDKWDRLLSGWRINKR
CCCEEEHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCE
LKLGELSTGMLMKVKIGGVLARKAKVYLYDEPFANIDIMARSEVMKAIISETEPDVITII
EEECCCCCCEEEEEEECCEEEECEEEEEEECCCCCEEEEHHHHHHHHHHCCCCCCEEEEE
SSHHLEGTEKLYNKLWLIKEGTLKIIETEDYREETGNSLIDFYKEEMNK
ECCCCCHHHHHHHHEEEEECCCEEEEECCHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure
MLVGNNIAKSYPNKLVLQNLDFEAKPGDMIVLTGENGSGKTTLLDMLANLKKPDSGTLEL
CCCCCCHHHHCCCEEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEE
DNEVFAANNIRQHIAYLNNELYAKKSITIEEFMKQHALLFEDIQLDKWDRLLSGWRINKR
CCCEEEHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCE
LKLGELSTGMLMKVKIGGVLARKAKVYLYDEPFANIDIMARSEVMKAIISETEPDVITII
EEECCCCCCEEEEEEECCEEEECEEEEEEECCCCCEEEEHHHHHHHHHHCCCCCCEEEEE
SSHHLEGTEKLYNKLWLIKEGTLKIIETEDYREETGNSLIDFYKEEMNK
ECCCCCHHHHHHHHEEEEECCCEEEEECCHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamine [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamine [Periplasm] + H2O = ADP + phosphate + L-glutamine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]