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The map label for this gene is ycsN [H]

Identifier: 116872027

GI number: 116872027

Start: 643362

End: 644279

Strand: Direct

Name: ycsN [H]

Synonym: lwe0607

Alternate gene names: 116872027

Gene position: 643362-644279 (Clockwise)

Preceding gene: 116872026

Following gene: 116872028

Centisome position: 22.86

GC content: 36.6

Gene sequence:

>918_bases
TTGAAACGAATAACAATTGGTAACAGCGCTTTAACAGCTTCAGAAATTTCGCTTGGATGTATGAGAATGGCGGATCTTAG
TAAAGAGGATGCAAATAAAGTAATTAACACAGCACTTGAAAACGGTATTGATTTTTTTGATCACGCAGATATTTATGGTG
GCGGTAAATCAGAAGAAGTCTTTGCTGATGCAATTGATATGAACGCAACGATTCGTGAAAAAATGATTCTTCAATCAAAA
TGTGGGATTCGTCAAGGATTCTTTGATTTTTCAAAAGAGCATATTATTTCTTCTGTAGAAGGTAGCTTAAAGCGCCTAAA
AACAGATTATTTAGATACACTATTACTTCATCGTCCGGATACACTTTTTGAACCAGAAGAAGTAGCAGCTGCTTTCACAG
AGCTAGAAAAAAGTGGAAAAGTTCGTCATTTTGGTGTAAGTAATCAAAATCCAGGTCAAATCGAGCTACTAAAAAAATAC
GTAGACCAAGAATTAATTGCCAACCAACTACAATTTAGCATTATGCACACAGGAATGATTGATACTGGTTTTAACGTAAA
TATGACGATTGATCCTTCGCTTGATCGTGATGGTGGTATTTTAGAATATAGTCGCTTAAATAATATGACTATCCAAGCAT
GGTCCCCGTTCCAATATGGTTTCTTTGAAGGGGTATTCTTAGATAACGATAAATTCCCTGAATTAAATAAAACAATCGAT
AAAATAGCTGCTGATAAAGGTGTAACCAATTCAGCAATTGCTGTGGCGTGGATTCAGCGCCATCCAGCTAGCTTCCAAAC
AGTTGTTGGTACAATGAATCCGGGAAGAATTGCAGACATCGCAAAAGCTTCTGATGTAACACTTAGCCGTGAAGAATGGT
ATGAAATTTACCGTGCGGCTGGAAATCAATTACCTTAA

Upstream 100 bases:

>100_bases
TACCGAAAAAGGGATTAATTTTTATTCAGAAGGTTAAGCTTGGTAACGATTACAACAAAGTGTTAGAATAAGGATATACT
TTTCGAAAGAGGTGCTTGAT

Downstream 100 bases:

>100_bases
TAGGAATAGACACTTGGGCATGTTGCTCAAGTGTTTTTTTATGTAATCGAATGATACTGAATTTCATTCTCAATTAGATA
TTAATTTTATCAATTAGTTT

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MKRITIGNSALTASEISLGCMRMADLSKEDANKVINTALENGIDFFDHADIYGGGKSEEVFADAIDMNATIREKMILQSK
CGIRQGFFDFSKEHIISSVEGSLKRLKTDYLDTLLLHRPDTLFEPEEVAAAFTELEKSGKVRHFGVSNQNPGQIELLKKY
VDQELIANQLQFSIMHTGMIDTGFNVNMTIDPSLDRDGGILEYSRLNNMTIQAWSPFQYGFFEGVFLDNDKFPELNKTID
KIAADKGVTNSAIAVAWIQRHPASFQTVVGTMNPGRIADIAKASDVTLSREEWYEIYRAAGNQLP

Sequences:

>Translated_305_residues
MKRITIGNSALTASEISLGCMRMADLSKEDANKVINTALENGIDFFDHADIYGGGKSEEVFADAIDMNATIREKMILQSK
CGIRQGFFDFSKEHIISSVEGSLKRLKTDYLDTLLLHRPDTLFEPEEVAAAFTELEKSGKVRHFGVSNQNPGQIELLKKY
VDQELIANQLQFSIMHTGMIDTGFNVNMTIDPSLDRDGGILEYSRLNNMTIQAWSPFQYGFFEGVFLDNDKFPELNKTID
KIAADKGVTNSAIAVAWIQRHPASFQTVVGTMNPGRIADIAKASDVTLSREEWYEIYRAAGNQLP
>Mature_305_residues
MKRITIGNSALTASEISLGCMRMADLSKEDANKVINTALENGIDFFDHADIYGGGKSEEVFADAIDMNATIREKMILQSK
CGIRQGFFDFSKEHIISSVEGSLKRLKTDYLDTLLLHRPDTLFEPEEVAAAFTELEKSGKVRHFGVSNQNPGQIELLKKY
VDQELIANQLQFSIMHTGMIDTGFNVNMTIDPSLDRDGGILEYSRLNNMTIQAWSPFQYGFFEGVFLDNDKFPELNKTID
KIAADKGVTNSAIAVAWIQRHPASFQTVVGTMNPGRIADIAKASDVTLSREEWYEIYRAAGNQLP

Specific function: Unknown

COG id: COG4989

COG function: function code R; Predicted oxidoreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=316, Percent_Identity=23.4177215189873, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI27436962, Length=311, Percent_Identity=23.1511254019293, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI27436966, Length=316, Percent_Identity=23.1012658227848, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI27436969, Length=295, Percent_Identity=24.7457627118644, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4504825, Length=294, Percent_Identity=24.4897959183673, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI27436971, Length=165, Percent_Identity=29.0909090909091, Blast_Score=75, Evalue=5e-14,
Organism=Escherichia coli, GI48994888, Length=317, Percent_Identity=33.1230283911672, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI87081735, Length=329, Percent_Identity=24.3161094224924, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1788070, Length=332, Percent_Identity=25, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1788081, Length=275, Percent_Identity=26.9090909090909, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1789375, Length=333, Percent_Identity=22.8228228228228, Blast_Score=71, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6325169, Length=347, Percent_Identity=24.207492795389, Blast_Score=99, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34033; Mature: 34033

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00136 SUBTILASE_ASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRITIGNSALTASEISLGCMRMADLSKEDANKVINTALENGIDFFDHADIYGGGKSEEV
CCEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCHH
FADAIDMNATIREKMILQSKCGIRQGFFDFSKEHIISSVEGSLKRLKTDYLDTLLLHRPD
HHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TLFEPEEVAAAFTELEKSGKVRHFGVSNQNPGQIELLKKYVDQELIANQLQFSIMHTGMI
CCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCE
DTGFNVNMTIDPSLDRDGGILEYSRLNNMTIQAWSPFQYGFFEGVFLDNDKFPELNKTID
ECCCEEEEEECCCCCCCCCEEEECCCCCEEEEEECCCCCCCEEEEEECCCCCCHHHHHHH
KIAADKGVTNSAIAVAWIQRHPASFQTVVGTMNPGRIADIAKASDVTLSREEWYEIYRAA
HHHHCCCCCCCHHEEEEHHHCCCCHHHEEECCCCCCHHHHHCCCCCEECHHHHHHHHHHH
GNQLP
CCCCC
>Mature Secondary Structure
MKRITIGNSALTASEISLGCMRMADLSKEDANKVINTALENGIDFFDHADIYGGGKSEEV
CCEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCHH
FADAIDMNATIREKMILQSKCGIRQGFFDFSKEHIISSVEGSLKRLKTDYLDTLLLHRPD
HHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TLFEPEEVAAAFTELEKSGKVRHFGVSNQNPGQIELLKKYVDQELIANQLQFSIMHTGMI
CCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCE
DTGFNVNMTIDPSLDRDGGILEYSRLNNMTIQAWSPFQYGFFEGVFLDNDKFPELNKTID
ECCCEEEEEECCCCCCCCCEEEECCCCCEEEEEECCCCCCCEEEEEECCCCCCHHHHHHH
KIAADKGVTNSAIAVAWIQRHPASFQTVVGTMNPGRIADIAKASDVTLSREEWYEIYRAA
HHHHCCCCCCCHHEEEEHHHCCCCHHHEEECCCCCCHHHHHCCCCCEECHHHHHHHHHHH
GNQLP
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]